Mesenchymal stromal cells: Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2007-02

AUTHORS

Catherine M Kolf, Elizabeth Cho, Rocky S Tuan

ABSTRACT

Recent advances in understanding the cellular and molecular signaling pathways and global transcriptional regulators of adult mesenchymal stem cells have provided new insights into their biology and potential clinical applications, particularly for tissue repair and regeneration. This review focuses on these advances, specifically in the context of self-renewal and regulation of lineage-specific differentiation of mesenchymal stem cells. In addition we review recent research on the concept of stem cell niche, and its relevance to adult mesenchymal stem cells. More... »

PAGES

204

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/ar2116

DOI

http://dx.doi.org/10.1186/ar2116

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032169750

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17316462


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