Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2004-09

AUTHORS

P'ng Loke, James P Allison

ABSTRACT

Whereas B7-1/B7-2 and CD28/cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) serve as the main switches regulating the clonal composition of activated naive T cells, other B7 family members fine-tune the expansion and properties of activated T cells. Inducible costimulatory molecule (ICOS)-B7h promotes T-dependent antibody isotype switching and expansion of effector cells. Effector T cells trafficking into inflamed tissues interact with antigen-presenting cells there and are regulated by PD-1 and its ligands. B7-H3 and B7x could control the interaction between effector T cells and the peripheral tissues. The different varieties of regulatory T cells could regulate both naive T cell activation and effector function through costimulatory receptor/ligands. More... »

PAGES

208

References to SciGraph publications

  • 2003-05. Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity in NATURE MEDICINE
  • 2003-05. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease in NATURE
  • 2002-02. Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance in NATURE IMMUNOLOGY
  • 2003-08. Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses in NATURE IMMUNOLOGY
  • 2003-02. CTLA-4 regulates the requirement for cytokine-induced signals in TH2 lineage commitment in NATURE IMMUNOLOGY
  • 2001-03. B7-H3: A costimulatory molecule for T cell activation and IFN-γ production in NATURE IMMUNOLOGY
  • 2002-07. CTLA-4: new insights into its biological function and use in tumor immunotherapy in NATURE IMMUNOLOGY
  • 1997-10. A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis in NATURE
  • 2002-09. Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity in NATURE MEDICINE
  • 2003-01. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype in NATURE
  • 2003-04. An essential role for Scurfin in CD4+CD25+ T regulatory cells in NATURE IMMUNOLOGY
  • 2003-12. Modulation of tryptophan catabolism by regulatory T cells in NATURE IMMUNOLOGY
  • 2003-04. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells in NATURE IMMUNOLOGY
  • 2003-09. The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses in NATURE IMMUNOLOGY
  • 2002-11. CTLA-4–Ig regulates tryptophan catabolism in vivo in NATURE IMMUNOLOGY
  • 2003-07. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 in NATURE IMMUNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/ar1225

    DOI

    http://dx.doi.org/10.1186/ar1225

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1002640528

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/15380035


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Immunology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Antigens, CD", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "B7-1 Antigen", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "B7-2 Antigen", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Immune System", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Membrane Glycoproteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "T-Lymphocytes", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of California, Berkeley", 
              "id": "https://www.grid.ac/institutes/grid.47840.3f", 
              "name": [
                "Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Loke", 
            "givenName": "P'ng", 
            "id": "sg:person.01102622437.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102622437.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, Berkeley", 
              "id": "https://www.grid.ac/institutes/grid.47840.3f", 
              "name": [
                "Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Allison", 
            "givenName": "James P", 
            "id": "sg:person.013745230632.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013745230632.15"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/s1074-7613(01)00259-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001155163"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni967", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001422927", 
              "https://doi.org/10.1038/ni967"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni967", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001422927", 
              "https://doi.org/10.1038/ni967"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni846", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001764721", 
              "https://doi.org/10.1038/ni846"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni846", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001764721", 
              "https://doi.org/10.1038/ni846"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.coi.2003.09.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002220848"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.coi.2003.09.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002220848"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni1003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002549018", 
              "https://doi.org/10.1038/ni1003"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni1003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002549018", 
              "https://doi.org/10.1038/ni1003"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01621", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004357092", 
              "https://doi.org/10.1038/nature01621"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01621", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004357092", 
              "https://doi.org/10.1038/nature01621"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.immuni.2004.06.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004930039"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(03)00147-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005016484"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.immunol.19.1.683", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005225110"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01315", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005567988", 
              "https://doi.org/10.1038/nature01315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01315", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005567988", 
              "https://doi.org/10.1038/nature01315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(00)80284-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008312845"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20020298", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008536963"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20022235", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009491946"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm745", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010343102", 
              "https://doi.org/10.1038/nm745"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm745", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010343102", 
              "https://doi.org/10.1038/nm745"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/85339", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011112369", 
              "https://doi.org/10.1038/85339"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/85339", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011112369", 
              "https://doi.org/10.1038/85339"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1078231", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011368985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20022089", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011548742"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni944", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014449844", 
              "https://doi.org/10.1038/ni944"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni944", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014449844", 
              "https://doi.org/10.1038/ni944"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0952-7915(02)00398-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016043733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20020632", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017876515"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(04)00050-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019451311"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm863", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019635782", 
              "https://doi.org/10.1038/nm863"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm863", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019635782", 
              "https://doi.org/10.1038/nm863"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0952-7915(02)00378-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020675193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.iy.07.040189.002305", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020907670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni759", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021808391", 
              "https://doi.org/10.1038/ni759"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni759", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021808391", 
              "https://doi.org/10.1038/ni759"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni947", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023001086", 
              "https://doi.org/10.1038/ni947"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni947", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023001086", 
              "https://doi.org/10.1038/ni947"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni0702-611", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024203574", 
              "https://doi.org/10.1038/ni0702-611"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni0702-611", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024203574", 
              "https://doi.org/10.1038/ni0702-611"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.immunol.18.1.367", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024965874"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.172.7.4100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026513597"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.220423597", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029749501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(03)00152-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031144294"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni884", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031636557", 
              "https://doi.org/10.1038/ni884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni884", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031636557", 
              "https://doi.org/10.1038/ni884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni909", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032222092", 
              "https://doi.org/10.1038/ni909"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni909", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032222092", 
              "https://doi.org/10.1038/ni909"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20011629", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032767073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/eji.200324270", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034464187"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.2334901100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034837935"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20030242", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038110890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(00)00011-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038551385"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20021466", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039946230"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1533209100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042168438"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood.v99.6.2138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042452185"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1434299100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042814615"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/eji.200324228", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043261839"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.171.9.4650", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043622656"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0830997100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045843488"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1079490", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047445436"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.20021752", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047835476"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00130832-200312000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047917659"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0931259100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048217395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.042684699", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048368635"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni904", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053106484", 
              "https://doi.org/10.1038/ni904"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni904", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053106484", 
              "https://doi.org/10.1038/ni904"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1074-7613(02)00280-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053270683"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/eji.200324084", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053516192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.169.10.5538", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053529581"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/39614", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053642209", 
              "https://doi.org/10.1038/39614"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/39614", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053642209", 
              "https://doi.org/10.1038/39614"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.8202711", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062653595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.169.7.3581", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1075128315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.170.5.2310", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1075240014"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.171.8.4156", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1076576951"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076581609", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4049/jimmunol.172.4.2530", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1076635548"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2004-09", 
        "datePublishedReg": "2004-09-01", 
        "description": "Whereas B7-1/B7-2 and CD28/cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) serve as the main switches regulating the clonal composition of activated naive T cells, other B7 family members fine-tune the expansion and properties of activated T cells. Inducible costimulatory molecule (ICOS)-B7h promotes T-dependent antibody isotype switching and expansion of effector cells. Effector T cells trafficking into inflamed tissues interact with antigen-presenting cells there and are regulated by PD-1 and its ligands. B7-H3 and B7x could control the interaction between effector T cells and the peripheral tissues. The different varieties of regulatory T cells could regulate both naive T cell activation and effector function through costimulatory receptor/ligands.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/ar1225", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1297499", 
            "issn": [
              "1478-6354", 
              "1478-6362"
            ], 
            "name": "Arthritis Research & Therapy", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "6"
          }
        ], 
        "name": "Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells", 
        "pagination": "208", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "0c9270ae216161188401d7a256f05830190651416f43877ab7f37174e644f029"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "15380035"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101154438"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/ar1225"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1002640528"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/ar1225", 
          "https://app.dimensions.ai/details/publication/pub.1002640528"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T17:31", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000509.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1186%2Far1225"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/ar1225'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/ar1225'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/ar1225'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/ar1225'


     

    This table displays all metadata directly associated to this object as RDF triples.

    306 TRIPLES      21 PREDICATES      98 URIs      29 LITERALS      17 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/ar1225 schema:about N054b28da53774611b8dd2ba7c6dab947
    2 N19233bfcbaf3472493ec4e58c54580a2
    3 N3007a2d3acf846da9febf89a5a5894b3
    4 N601521dea8a74b5b88aec6cc7748f3e3
    5 N90727927c3924ca49ea9b60bcdde97cc
    6 N91ac03bb79cc41ddbc6613bfe5508753
    7 N98c3cac8ed1e4f71b1d1195a767e862a
    8 Nc2340393139a4b1cae5f6e311c15d65f
    9 anzsrc-for:11
    10 anzsrc-for:1107
    11 schema:author N4849f7d1c7564769b3600fd92fbc843f
    12 schema:citation sg:pub.10.1038/39614
    13 sg:pub.10.1038/85339
    14 sg:pub.10.1038/nature01315
    15 sg:pub.10.1038/nature01621
    16 sg:pub.10.1038/ni0702-611
    17 sg:pub.10.1038/ni1003
    18 sg:pub.10.1038/ni759
    19 sg:pub.10.1038/ni846
    20 sg:pub.10.1038/ni884
    21 sg:pub.10.1038/ni904
    22 sg:pub.10.1038/ni909
    23 sg:pub.10.1038/ni944
    24 sg:pub.10.1038/ni947
    25 sg:pub.10.1038/ni967
    26 sg:pub.10.1038/nm745
    27 sg:pub.10.1038/nm863
    28 https://app.dimensions.ai/details/publication/pub.1076581609
    29 https://doi.org/10.1002/eji.200324084
    30 https://doi.org/10.1002/eji.200324228
    31 https://doi.org/10.1002/eji.200324270
    32 https://doi.org/10.1016/j.coi.2003.09.011
    33 https://doi.org/10.1016/j.immuni.2004.06.017
    34 https://doi.org/10.1016/s0952-7915(02)00378-3
    35 https://doi.org/10.1016/s0952-7915(02)00398-9
    36 https://doi.org/10.1016/s1074-7613(00)00011-x
    37 https://doi.org/10.1016/s1074-7613(00)80284-8
    38 https://doi.org/10.1016/s1074-7613(01)00259-x
    39 https://doi.org/10.1016/s1074-7613(02)00280-7
    40 https://doi.org/10.1016/s1074-7613(03)00147-x
    41 https://doi.org/10.1016/s1074-7613(03)00152-3
    42 https://doi.org/10.1016/s1074-7613(04)00050-0
    43 https://doi.org/10.1073/pnas.042684699
    44 https://doi.org/10.1073/pnas.0830997100
    45 https://doi.org/10.1073/pnas.0931259100
    46 https://doi.org/10.1073/pnas.1434299100
    47 https://doi.org/10.1073/pnas.1533209100
    48 https://doi.org/10.1073/pnas.220423597
    49 https://doi.org/10.1073/pnas.2334901100
    50 https://doi.org/10.1084/jem.20011629
    51 https://doi.org/10.1084/jem.20020298
    52 https://doi.org/10.1084/jem.20020632
    53 https://doi.org/10.1084/jem.20021466
    54 https://doi.org/10.1084/jem.20021752
    55 https://doi.org/10.1084/jem.20022089
    56 https://doi.org/10.1084/jem.20022235
    57 https://doi.org/10.1084/jem.20030242
    58 https://doi.org/10.1097/00130832-200312000-00001
    59 https://doi.org/10.1126/science.1078231
    60 https://doi.org/10.1126/science.1079490
    61 https://doi.org/10.1126/science.8202711
    62 https://doi.org/10.1146/annurev.immunol.18.1.367
    63 https://doi.org/10.1146/annurev.immunol.19.1.683
    64 https://doi.org/10.1146/annurev.iy.07.040189.002305
    65 https://doi.org/10.1182/blood.v99.6.2138
    66 https://doi.org/10.4049/jimmunol.169.10.5538
    67 https://doi.org/10.4049/jimmunol.169.7.3581
    68 https://doi.org/10.4049/jimmunol.170.5.2310
    69 https://doi.org/10.4049/jimmunol.171.8.4156
    70 https://doi.org/10.4049/jimmunol.171.9.4650
    71 https://doi.org/10.4049/jimmunol.172.4.2530
    72 https://doi.org/10.4049/jimmunol.172.7.4100
    73 schema:datePublished 2004-09
    74 schema:datePublishedReg 2004-09-01
    75 schema:description Whereas B7-1/B7-2 and CD28/cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) serve as the main switches regulating the clonal composition of activated naive T cells, other B7 family members fine-tune the expansion and properties of activated T cells. Inducible costimulatory molecule (ICOS)-B7h promotes T-dependent antibody isotype switching and expansion of effector cells. Effector T cells trafficking into inflamed tissues interact with antigen-presenting cells there and are regulated by PD-1 and its ligands. B7-H3 and B7x could control the interaction between effector T cells and the peripheral tissues. The different varieties of regulatory T cells could regulate both naive T cell activation and effector function through costimulatory receptor/ligands.
    76 schema:genre research_article
    77 schema:inLanguage en
    78 schema:isAccessibleForFree true
    79 schema:isPartOf N613756bdd83a4d93855d9b6c2e2d4edd
    80 Nf1c04fc1e44643d9ad579544f4ffe0d5
    81 sg:journal.1297499
    82 schema:name Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells
    83 schema:pagination 208
    84 schema:productId N0acede0a7a1c48f4b5c1a79fcf15129f
    85 N21c3e03a8680428985f936a260117fcc
    86 Nae0281162e8f4c06b9fd69f0a8ff4a40
    87 Nec0467aebf6842de8e8b013d56eba344
    88 Nfde287971bd64f14acb853c6901631fe
    89 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002640528
    90 https://doi.org/10.1186/ar1225
    91 schema:sdDatePublished 2019-04-10T17:31
    92 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    93 schema:sdPublisher N333166222f9e450e85b27d8944e0af42
    94 schema:url http://link.springer.com/10.1186%2Far1225
    95 sgo:license sg:explorer/license/
    96 sgo:sdDataset articles
    97 rdf:type schema:ScholarlyArticle
    98 N054b28da53774611b8dd2ba7c6dab947 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    99 schema:name Membrane Glycoproteins
    100 rdf:type schema:DefinedTerm
    101 N0acede0a7a1c48f4b5c1a79fcf15129f schema:name doi
    102 schema:value 10.1186/ar1225
    103 rdf:type schema:PropertyValue
    104 N19233bfcbaf3472493ec4e58c54580a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    105 schema:name Immune System
    106 rdf:type schema:DefinedTerm
    107 N21c3e03a8680428985f936a260117fcc schema:name pubmed_id
    108 schema:value 15380035
    109 rdf:type schema:PropertyValue
    110 N3007a2d3acf846da9febf89a5a5894b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name T-Lymphocytes
    112 rdf:type schema:DefinedTerm
    113 N333166222f9e450e85b27d8944e0af42 schema:name Springer Nature - SN SciGraph project
    114 rdf:type schema:Organization
    115 N4849f7d1c7564769b3600fd92fbc843f rdf:first sg:person.01102622437.30
    116 rdf:rest Nabc09c485b7a4e1099cc65cfbc4ebf5a
    117 N601521dea8a74b5b88aec6cc7748f3e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Humans
    119 rdf:type schema:DefinedTerm
    120 N613756bdd83a4d93855d9b6c2e2d4edd schema:issueNumber 5
    121 rdf:type schema:PublicationIssue
    122 N90727927c3924ca49ea9b60bcdde97cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    123 schema:name Antigens, CD
    124 rdf:type schema:DefinedTerm
    125 N91ac03bb79cc41ddbc6613bfe5508753 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    126 schema:name B7-2 Antigen
    127 rdf:type schema:DefinedTerm
    128 N98c3cac8ed1e4f71b1d1195a767e862a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    129 schema:name B7-1 Antigen
    130 rdf:type schema:DefinedTerm
    131 Nabc09c485b7a4e1099cc65cfbc4ebf5a rdf:first sg:person.013745230632.15
    132 rdf:rest rdf:nil
    133 Nae0281162e8f4c06b9fd69f0a8ff4a40 schema:name nlm_unique_id
    134 schema:value 101154438
    135 rdf:type schema:PropertyValue
    136 Nc2340393139a4b1cae5f6e311c15d65f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    137 schema:name Animals
    138 rdf:type schema:DefinedTerm
    139 Nec0467aebf6842de8e8b013d56eba344 schema:name dimensions_id
    140 schema:value pub.1002640528
    141 rdf:type schema:PropertyValue
    142 Nf1c04fc1e44643d9ad579544f4ffe0d5 schema:volumeNumber 6
    143 rdf:type schema:PublicationVolume
    144 Nfde287971bd64f14acb853c6901631fe schema:name readcube_id
    145 schema:value 0c9270ae216161188401d7a256f05830190651416f43877ab7f37174e644f029
    146 rdf:type schema:PropertyValue
    147 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    148 schema:name Medical and Health Sciences
    149 rdf:type schema:DefinedTerm
    150 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
    151 schema:name Immunology
    152 rdf:type schema:DefinedTerm
    153 sg:journal.1297499 schema:issn 1478-6354
    154 1478-6362
    155 schema:name Arthritis Research & Therapy
    156 rdf:type schema:Periodical
    157 sg:person.01102622437.30 schema:affiliation https://www.grid.ac/institutes/grid.47840.3f
    158 schema:familyName Loke
    159 schema:givenName P'ng
    160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102622437.30
    161 rdf:type schema:Person
    162 sg:person.013745230632.15 schema:affiliation https://www.grid.ac/institutes/grid.47840.3f
    163 schema:familyName Allison
    164 schema:givenName James P
    165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013745230632.15
    166 rdf:type schema:Person
    167 sg:pub.10.1038/39614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053642209
    168 https://doi.org/10.1038/39614
    169 rdf:type schema:CreativeWork
    170 sg:pub.10.1038/85339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011112369
    171 https://doi.org/10.1038/85339
    172 rdf:type schema:CreativeWork
    173 sg:pub.10.1038/nature01315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005567988
    174 https://doi.org/10.1038/nature01315
    175 rdf:type schema:CreativeWork
    176 sg:pub.10.1038/nature01621 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004357092
    177 https://doi.org/10.1038/nature01621
    178 rdf:type schema:CreativeWork
    179 sg:pub.10.1038/ni0702-611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024203574
    180 https://doi.org/10.1038/ni0702-611
    181 rdf:type schema:CreativeWork
    182 sg:pub.10.1038/ni1003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002549018
    183 https://doi.org/10.1038/ni1003
    184 rdf:type schema:CreativeWork
    185 sg:pub.10.1038/ni759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021808391
    186 https://doi.org/10.1038/ni759
    187 rdf:type schema:CreativeWork
    188 sg:pub.10.1038/ni846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001764721
    189 https://doi.org/10.1038/ni846
    190 rdf:type schema:CreativeWork
    191 sg:pub.10.1038/ni884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031636557
    192 https://doi.org/10.1038/ni884
    193 rdf:type schema:CreativeWork
    194 sg:pub.10.1038/ni904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053106484
    195 https://doi.org/10.1038/ni904
    196 rdf:type schema:CreativeWork
    197 sg:pub.10.1038/ni909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032222092
    198 https://doi.org/10.1038/ni909
    199 rdf:type schema:CreativeWork
    200 sg:pub.10.1038/ni944 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014449844
    201 https://doi.org/10.1038/ni944
    202 rdf:type schema:CreativeWork
    203 sg:pub.10.1038/ni947 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023001086
    204 https://doi.org/10.1038/ni947
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1038/ni967 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001422927
    207 https://doi.org/10.1038/ni967
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1038/nm745 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010343102
    210 https://doi.org/10.1038/nm745
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1038/nm863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019635782
    213 https://doi.org/10.1038/nm863
    214 rdf:type schema:CreativeWork
    215 https://app.dimensions.ai/details/publication/pub.1076581609 schema:CreativeWork
    216 https://doi.org/10.1002/eji.200324084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053516192
    217 rdf:type schema:CreativeWork
    218 https://doi.org/10.1002/eji.200324228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043261839
    219 rdf:type schema:CreativeWork
    220 https://doi.org/10.1002/eji.200324270 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034464187
    221 rdf:type schema:CreativeWork
    222 https://doi.org/10.1016/j.coi.2003.09.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002220848
    223 rdf:type schema:CreativeWork
    224 https://doi.org/10.1016/j.immuni.2004.06.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004930039
    225 rdf:type schema:CreativeWork
    226 https://doi.org/10.1016/s0952-7915(02)00378-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020675193
    227 rdf:type schema:CreativeWork
    228 https://doi.org/10.1016/s0952-7915(02)00398-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016043733
    229 rdf:type schema:CreativeWork
    230 https://doi.org/10.1016/s1074-7613(00)00011-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038551385
    231 rdf:type schema:CreativeWork
    232 https://doi.org/10.1016/s1074-7613(00)80284-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008312845
    233 rdf:type schema:CreativeWork
    234 https://doi.org/10.1016/s1074-7613(01)00259-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001155163
    235 rdf:type schema:CreativeWork
    236 https://doi.org/10.1016/s1074-7613(02)00280-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053270683
    237 rdf:type schema:CreativeWork
    238 https://doi.org/10.1016/s1074-7613(03)00147-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005016484
    239 rdf:type schema:CreativeWork
    240 https://doi.org/10.1016/s1074-7613(03)00152-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031144294
    241 rdf:type schema:CreativeWork
    242 https://doi.org/10.1016/s1074-7613(04)00050-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019451311
    243 rdf:type schema:CreativeWork
    244 https://doi.org/10.1073/pnas.042684699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048368635
    245 rdf:type schema:CreativeWork
    246 https://doi.org/10.1073/pnas.0830997100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045843488
    247 rdf:type schema:CreativeWork
    248 https://doi.org/10.1073/pnas.0931259100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048217395
    249 rdf:type schema:CreativeWork
    250 https://doi.org/10.1073/pnas.1434299100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042814615
    251 rdf:type schema:CreativeWork
    252 https://doi.org/10.1073/pnas.1533209100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042168438
    253 rdf:type schema:CreativeWork
    254 https://doi.org/10.1073/pnas.220423597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029749501
    255 rdf:type schema:CreativeWork
    256 https://doi.org/10.1073/pnas.2334901100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034837935
    257 rdf:type schema:CreativeWork
    258 https://doi.org/10.1084/jem.20011629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032767073
    259 rdf:type schema:CreativeWork
    260 https://doi.org/10.1084/jem.20020298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008536963
    261 rdf:type schema:CreativeWork
    262 https://doi.org/10.1084/jem.20020632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017876515
    263 rdf:type schema:CreativeWork
    264 https://doi.org/10.1084/jem.20021466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039946230
    265 rdf:type schema:CreativeWork
    266 https://doi.org/10.1084/jem.20021752 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047835476
    267 rdf:type schema:CreativeWork
    268 https://doi.org/10.1084/jem.20022089 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011548742
    269 rdf:type schema:CreativeWork
    270 https://doi.org/10.1084/jem.20022235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009491946
    271 rdf:type schema:CreativeWork
    272 https://doi.org/10.1084/jem.20030242 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038110890
    273 rdf:type schema:CreativeWork
    274 https://doi.org/10.1097/00130832-200312000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047917659
    275 rdf:type schema:CreativeWork
    276 https://doi.org/10.1126/science.1078231 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011368985
    277 rdf:type schema:CreativeWork
    278 https://doi.org/10.1126/science.1079490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047445436
    279 rdf:type schema:CreativeWork
    280 https://doi.org/10.1126/science.8202711 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062653595
    281 rdf:type schema:CreativeWork
    282 https://doi.org/10.1146/annurev.immunol.18.1.367 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024965874
    283 rdf:type schema:CreativeWork
    284 https://doi.org/10.1146/annurev.immunol.19.1.683 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005225110
    285 rdf:type schema:CreativeWork
    286 https://doi.org/10.1146/annurev.iy.07.040189.002305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020907670
    287 rdf:type schema:CreativeWork
    288 https://doi.org/10.1182/blood.v99.6.2138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042452185
    289 rdf:type schema:CreativeWork
    290 https://doi.org/10.4049/jimmunol.169.10.5538 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053529581
    291 rdf:type schema:CreativeWork
    292 https://doi.org/10.4049/jimmunol.169.7.3581 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075128315
    293 rdf:type schema:CreativeWork
    294 https://doi.org/10.4049/jimmunol.170.5.2310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075240014
    295 rdf:type schema:CreativeWork
    296 https://doi.org/10.4049/jimmunol.171.8.4156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076576951
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.4049/jimmunol.171.9.4650 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043622656
    299 rdf:type schema:CreativeWork
    300 https://doi.org/10.4049/jimmunol.172.4.2530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076635548
    301 rdf:type schema:CreativeWork
    302 https://doi.org/10.4049/jimmunol.172.7.4100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026513597
    303 rdf:type schema:CreativeWork
    304 https://www.grid.ac/institutes/grid.47840.3f schema:alternateName University of California, Berkeley
    305 schema:name Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA
    306 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...