What makes cancer stem cell markers different? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Uwe Karsten, Steffen Goletz

ABSTRACT

Since the cancer stem cell concept has been widely accepted, several strategies have been proposed to attack cancer stem cells (CSC). Accordingly, stem cell markers are now preferred therapeutic targets. However, the problem of tumor specificity has not disappeared but shifted to another question: how can cancer stem cells be distinguished from normal stem cells, or more specifically, how do CSC markers differ from normal stem cell markers? A hypothesis is proposed which might help to solve this problem in at least a subgroup of stem cell markers. Glycosylation may provide the key. More... »

PAGES

301

Journal

TITLE

SpringerPlus

ISSUE

1

VOLUME

2

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/2193-1801-2-301

DOI

http://dx.doi.org/10.1186/2193-1801-2-301

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025275071

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23888272


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