Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-12

AUTHORS

Huai-Chin Chiang, Sreejith J Nair, I-Tien Yeh, Alfredo A Santillan, Yanfen Hu, Richard Elledge, Rong Li

ABSTRACT

Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of BRCA1-associated cancer remains unclear. Here we studied fresh breast tissue from a BRCA1 mutation carrier who was initially treated with a lumpectomy and RT for a unilateral cancer and two years later chose a prophylactic bilateral mastectomy while remaining cancer-free. Flow cytometry analysis demonstrated a strikingly lower luminal cell population in the irradiated breast as compared to the non-irradiated breast, which was confirmed by immunohistochemistry. Furthermore, the irradiated breast tissue exhibited very low progenitor cell activity in vitro. Given the emerging evidence that BRCA1 tumors originate from luminal progenitor cells, our observations suggest that preferential and long-lasting elimination of luminal ductal epithelium may partly underlie the mechanism of RT-associated reduction in recurrence of BRCA1-associated cancer. More... »

PAGES

31

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/2162-3619-1-31

DOI

http://dx.doi.org/10.1186/2162-3619-1-31

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031634291

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23210696


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chiang", 
        "givenName": "Huai-Chin", 
        "id": "sg:person.01311040104.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311040104.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nair", 
        "givenName": "Sreejith J", 
        "id": "sg:person.0615227516.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615227516.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Medicine, Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yeh", 
        "givenName": "I-Tien", 
        "id": "sg:person.014552653337.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014552653337.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Medicine, Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Santillan", 
        "givenName": "Alfredo A", 
        "id": "sg:person.0736647067.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736647067.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hu", 
        "givenName": "Yanfen", 
        "id": "sg:person.0653503375.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653503375.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Medicine, Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Elledge", 
        "givenName": "Richard", 
        "id": "sg:person.01253032564.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253032564.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Rong", 
        "id": "sg:person.0655145177.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655145177.65"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1200/jco.2007.11.0379", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000730181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcp.10257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004338049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.1791", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013358013", 
          "https://doi.org/10.1038/nm.1791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1010615124301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013545902", 
          "https://doi.org/10.1023/a:1010615124301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016211736", 
          "https://doi.org/10.1038/nrc1431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016211736", 
          "https://doi.org/10.1038/nrc1431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(11)61629-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019167359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.stem.2010.07.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024464845"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19850901)56:5<979::aid-cncr2820560502>3.0.co;2-n", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031176250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/bgq069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033130899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040185730", 
          "https://doi.org/10.1038/nature04496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040185730", 
          "https://doi.org/10.1038/nature04496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040185730", 
          "https://doi.org/10.1038/nature04496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67887-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040467534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045151043", 
          "https://doi.org/10.1038/nm.2000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045151043", 
          "https://doi.org/10.1038/nm.2000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.stem.2010.12.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045228325"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/path.2457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045510384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-010-1336-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045600243", 
          "https://doi.org/10.1007/s10549-010-1336-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ppo.0b013e3181cf0204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046895053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ppo.0b013e3181cf0204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046895053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ppo.0b013e3181cf0204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046895053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1990.8.1.113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078390138"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2012-12", 
    "datePublishedReg": "2012-12-01", 
    "description": " Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of BRCA1-associated cancer remains unclear. Here we studied fresh breast tissue from a BRCA1 mutation carrier who was initially treated with a lumpectomy and RT for a unilateral cancer and two years later chose a prophylactic bilateral mastectomy while remaining cancer-free. Flow cytometry analysis demonstrated a strikingly lower luminal cell population in the irradiated breast as compared to the non-irradiated breast, which was confirmed by immunohistochemistry. Furthermore, the irradiated breast tissue exhibited very low progenitor cell activity in vitro. Given the emerging evidence that BRCA1 tumors originate from luminal progenitor cells, our observations suggest that preferential and long-lasting elimination of luminal ductal epithelium may partly underlie the mechanism of RT-associated reduction in recurrence of BRCA1-associated cancer.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/2162-3619-1-31", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2478503", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2475774", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1047344", 
        "issn": [
          "2162-3619"
        ], 
        "name": "Experimental Hematology & Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "1"
      }
    ], 
    "name": "Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier", 
    "pagination": "31", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "96b2f7e7bd3774ea64eccfcdbfc4ff6becf1f57142473aba75d725a7bc6e0399"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23210696"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101590676"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/2162-3619-1-31"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1031634291"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/2162-3619-1-31", 
      "https://app.dimensions.ai/details/publication/pub.1031634291"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89804_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F2162-3619-1-31"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/2162-3619-1-31'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/2162-3619-1-31'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/2162-3619-1-31'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/2162-3619-1-31'


 

This table displays all metadata directly associated to this object as RDF triples.

172 TRIPLES      21 PREDICATES      46 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/2162-3619-1-31 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author Ndc12d75ee96149fc8e1a9030a97884bb
4 schema:citation sg:pub.10.1007/s10549-010-1336-7
5 sg:pub.10.1023/a:1010615124301
6 sg:pub.10.1038/nature04496
7 sg:pub.10.1038/nm.1791
8 sg:pub.10.1038/nm.2000
9 sg:pub.10.1038/nrc1431
10 https://doi.org/10.1002/1097-0142(19850901)56:5<979::aid-cncr2820560502>3.0.co;2-n
11 https://doi.org/10.1002/jcp.10257
12 https://doi.org/10.1002/path.2457
13 https://doi.org/10.1016/j.stem.2010.07.010
14 https://doi.org/10.1016/j.stem.2010.12.007
15 https://doi.org/10.1016/s0140-6736(05)67887-7
16 https://doi.org/10.1016/s0140-6736(11)61629-2
17 https://doi.org/10.1093/carcin/bgq069
18 https://doi.org/10.1097/ppo.0b013e3181cf0204
19 https://doi.org/10.1200/jco.1990.8.1.113
20 https://doi.org/10.1200/jco.2007.11.0379
21 schema:datePublished 2012-12
22 schema:datePublishedReg 2012-12-01
23 schema:description Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of BRCA1-associated cancer remains unclear. Here we studied fresh breast tissue from a BRCA1 mutation carrier who was initially treated with a lumpectomy and RT for a unilateral cancer and two years later chose a prophylactic bilateral mastectomy while remaining cancer-free. Flow cytometry analysis demonstrated a strikingly lower luminal cell population in the irradiated breast as compared to the non-irradiated breast, which was confirmed by immunohistochemistry. Furthermore, the irradiated breast tissue exhibited very low progenitor cell activity in vitro. Given the emerging evidence that BRCA1 tumors originate from luminal progenitor cells, our observations suggest that preferential and long-lasting elimination of luminal ductal epithelium may partly underlie the mechanism of RT-associated reduction in recurrence of BRCA1-associated cancer.
24 schema:genre research_article
25 schema:inLanguage en
26 schema:isAccessibleForFree true
27 schema:isPartOf Nee127dcd1e56499795567261da4146f0
28 Nfe1a5460500440829eb55d980f6083f0
29 sg:journal.1047344
30 schema:name Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier
31 schema:pagination 31
32 schema:productId N27edf178a5ba4a17978ff93bf539cc93
33 N32aa6a7e9c324b6aa763e0a8d2a91db8
34 Na3b25e3f97774796b772045f3776f3c1
35 Ne2ed663250874d39aae9ee4f60b6c3ec
36 Nff4b8c174c574da4ab77f07dd9dd2bdc
37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031634291
38 https://doi.org/10.1186/2162-3619-1-31
39 schema:sdDatePublished 2019-04-11T09:56
40 schema:sdLicense https://scigraph.springernature.com/explorer/license/
41 schema:sdPublisher N30289b1c2c7d4a6292d1fc1ce1b0c93e
42 schema:url http://link.springer.com/10.1186%2F2162-3619-1-31
43 sgo:license sg:explorer/license/
44 sgo:sdDataset articles
45 rdf:type schema:ScholarlyArticle
46 N10655bddea8b4e95918bb086240f0d32 rdf:first sg:person.0653503375.89
47 rdf:rest Ncfeeef47294b4c23943faa333e5f3955
48 N1f58fb93492748569b5f3c812a6ede28 rdf:first sg:person.0615227516.45
49 rdf:rest Nab945a4482c640cfa37123d18d250d3e
50 N25056a1485554564bffe606681d6a536 rdf:first sg:person.0736647067.46
51 rdf:rest N10655bddea8b4e95918bb086240f0d32
52 N27edf178a5ba4a17978ff93bf539cc93 schema:name pubmed_id
53 schema:value 23210696
54 rdf:type schema:PropertyValue
55 N30289b1c2c7d4a6292d1fc1ce1b0c93e schema:name Springer Nature - SN SciGraph project
56 rdf:type schema:Organization
57 N32aa6a7e9c324b6aa763e0a8d2a91db8 schema:name nlm_unique_id
58 schema:value 101590676
59 rdf:type schema:PropertyValue
60 N7bb1b96737f147b3aabaff121de1d851 rdf:first sg:person.0655145177.65
61 rdf:rest rdf:nil
62 Na3b25e3f97774796b772045f3776f3c1 schema:name readcube_id
63 schema:value 96b2f7e7bd3774ea64eccfcdbfc4ff6becf1f57142473aba75d725a7bc6e0399
64 rdf:type schema:PropertyValue
65 Nab945a4482c640cfa37123d18d250d3e rdf:first sg:person.014552653337.45
66 rdf:rest N25056a1485554564bffe606681d6a536
67 Ncfeeef47294b4c23943faa333e5f3955 rdf:first sg:person.01253032564.40
68 rdf:rest N7bb1b96737f147b3aabaff121de1d851
69 Ndc12d75ee96149fc8e1a9030a97884bb rdf:first sg:person.01311040104.80
70 rdf:rest N1f58fb93492748569b5f3c812a6ede28
71 Ne2ed663250874d39aae9ee4f60b6c3ec schema:name doi
72 schema:value 10.1186/2162-3619-1-31
73 rdf:type schema:PropertyValue
74 Nee127dcd1e56499795567261da4146f0 schema:issueNumber 1
75 rdf:type schema:PublicationIssue
76 Nfe1a5460500440829eb55d980f6083f0 schema:volumeNumber 1
77 rdf:type schema:PublicationVolume
78 Nff4b8c174c574da4ab77f07dd9dd2bdc schema:name dimensions_id
79 schema:value pub.1031634291
80 rdf:type schema:PropertyValue
81 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
82 schema:name Medical and Health Sciences
83 rdf:type schema:DefinedTerm
84 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
85 schema:name Oncology and Carcinogenesis
86 rdf:type schema:DefinedTerm
87 sg:grant.2475774 http://pending.schema.org/fundedItem sg:pub.10.1186/2162-3619-1-31
88 rdf:type schema:MonetaryGrant
89 sg:grant.2478503 http://pending.schema.org/fundedItem sg:pub.10.1186/2162-3619-1-31
90 rdf:type schema:MonetaryGrant
91 sg:journal.1047344 schema:issn 2162-3619
92 schema:name Experimental Hematology & Oncology
93 rdf:type schema:Periodical
94 sg:person.01253032564.40 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
95 schema:familyName Elledge
96 schema:givenName Richard
97 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253032564.40
98 rdf:type schema:Person
99 sg:person.01311040104.80 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
100 schema:familyName Chiang
101 schema:givenName Huai-Chin
102 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311040104.80
103 rdf:type schema:Person
104 sg:person.014552653337.45 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
105 schema:familyName Yeh
106 schema:givenName I-Tien
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014552653337.45
108 rdf:type schema:Person
109 sg:person.0615227516.45 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
110 schema:familyName Nair
111 schema:givenName Sreejith J
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615227516.45
113 rdf:type schema:Person
114 sg:person.0653503375.89 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
115 schema:familyName Hu
116 schema:givenName Yanfen
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653503375.89
118 rdf:type schema:Person
119 sg:person.0655145177.65 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
120 schema:familyName Li
121 schema:givenName Rong
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655145177.65
123 rdf:type schema:Person
124 sg:person.0736647067.46 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
125 schema:familyName Santillan
126 schema:givenName Alfredo A
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736647067.46
128 rdf:type schema:Person
129 sg:pub.10.1007/s10549-010-1336-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045600243
130 https://doi.org/10.1007/s10549-010-1336-7
131 rdf:type schema:CreativeWork
132 sg:pub.10.1023/a:1010615124301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013545902
133 https://doi.org/10.1023/a:1010615124301
134 rdf:type schema:CreativeWork
135 sg:pub.10.1038/nature04496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040185730
136 https://doi.org/10.1038/nature04496
137 rdf:type schema:CreativeWork
138 sg:pub.10.1038/nm.1791 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013358013
139 https://doi.org/10.1038/nm.1791
140 rdf:type schema:CreativeWork
141 sg:pub.10.1038/nm.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045151043
142 https://doi.org/10.1038/nm.2000
143 rdf:type schema:CreativeWork
144 sg:pub.10.1038/nrc1431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016211736
145 https://doi.org/10.1038/nrc1431
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1002/1097-0142(19850901)56:5<979::aid-cncr2820560502>3.0.co;2-n schema:sameAs https://app.dimensions.ai/details/publication/pub.1031176250
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1002/jcp.10257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004338049
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1002/path.2457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045510384
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/j.stem.2010.07.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024464845
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/j.stem.2010.12.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045228325
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/s0140-6736(05)67887-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040467534
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/s0140-6736(11)61629-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019167359
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1093/carcin/bgq069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033130899
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1097/ppo.0b013e3181cf0204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046895053
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1200/jco.1990.8.1.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078390138
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1200/jco.2007.11.0379 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000730181
168 rdf:type schema:CreativeWork
169 https://www.grid.ac/institutes/grid.267309.9 schema:alternateName The University of Texas Health Science Center at San Antonio
170 schema:name Department of Medicine, Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA
171 Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 78245, San Antonio, TX, USA
172 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...