Bioengineering of a human whole tooth: progress and challenge View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Yanding Zhang, YiPing Chen

ABSTRACT

A major challenge in stem cell-based bioengineering of an implantable human tooth is to identify appropriate sources of postnatal stem cells that are odontogenic competent as the epithelial component due to the lack of enamel epithelial cells in adult teeth. In a recent issue (2013, 2:6) of Cell Regeneration, Cai and colleagues reported that epithelial sheets derived from human induced pluripotent stem cells (iPSCs) can functionally substitute for tooth germ epithelium to regenerate tooth-like structures, providing an appealing stem cell source for future human tooth regeneration. More... »

PAGES

8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/2045-9769-3-8

DOI

http://dx.doi.org/10.1186/2045-9769-3-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004595734

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25408887


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