Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-07-25

AUTHORS

Zafiria G Papathanassiou, Marco Alberghini, Philippe Thiesse, Marco Gambarotti, Giuseppe Bianchi, Cristina Tranfaglia, Daniel Vanel

ABSTRACT

ObjectiveParosteal osteosarcoma is a well-differentiated variant of osteosarcoma that affects the surface of the bone. The imaging pattern is very typical. We report two cases mimicking an osteochondroma, radiologically and histologically and propose an explanation.MaterialThe review of 86 parosteal osteosarcomas of bone revealed this atypical pattern only once. A consultation case was received in the same time, and added to ours. Patients were 28 years old and 56 years old females. Imaging studies included two radiographs, two CTscans, one MRI examination and one bone scan and the results were compared to histology.ResultsOn imaging, both lesions presented as ossified lobulated masses attached with a broad base to the underlying cortex. No radiolucent cleft separated the masses and the host bone and cortex continuity between the mass and the femur was seen, with medullary communication. The marrow of the mass had a different density and intensity compared to normal marrow. So, there were features of an osteochondroma (cortex and medullary continuity) and of a parosteal osteosarcoma (ossified marrow). Pathological assessment on the final specimen confirmed the presence of low-grade parosteal osteosarcomas, after an erroneous diagnosis of osteochondroma on the initial biopsy.ConclusionsParosteal osteosarcoma can be rarely confused with osteochondroma. A radiologic-pathologic correlation is essential. Cortex continuity is the most misleading imaging feature that may occur in parosteal osteosarcomas. A knowledge of this misleading pattern will help diagnose the lesion from the beginning. More... »

PAGES

2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/2045-3329-1-2

DOI

http://dx.doi.org/10.1186/2045-3329-1-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019059342

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22613734


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