Francisella tularensis subsp. novicida isolated from a human in Arizona View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-11-06

AUTHORS

Dawn N Birdsell, Tasha Stewart, Amy J Vogler, Elisabeth Lawaczeck, Alisa Diggs, Tammy L Sylvester, Jordan L Buchhagen, Raymond K Auerbach, Paul Keim, David M Wagner

ABSTRACT

BACKGROUND: Francisella tularensis is the etiologic agent of tularemia and is classified as a select agent by the Centers for Disease Control and Prevention. Currently four known subspecies of F. tularensis that differ in virulence and geographical distribution are recognized:tularensis (type A), holarctica (type B), mediasiatica, and novicida. Because of the Select Agent status and differences in virulence and geographical location, the molecular analysis of any clinical case of tularemia is of particular interest. We analyzed an unusual Francisella clinical isolate from a human infection in Arizona using multiple DNA-based approaches. FINDINGS: We report that the isolate is F. tularensis subsp. novicida, a subspecies that is rarely isolated. CONCLUSION: The rarity of this novicida subspecies in clinical settings makes each case study important for our understanding of its role in disease and its genetic relationship with other F. tularensis subspecies. More... »

PAGES

223-223

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1756-0500-2-223

DOI

http://dx.doi.org/10.1186/1756-0500-2-223

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037395386

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19895698


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187 grid-institutes:grid.47100.32 schema:alternateName Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA
188 schema:name Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ 86011-4073, USA
189 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA
190 rdf:type schema:Organization
191 grid-institutes:grid.490644.b schema:alternateName Maricopa County Department of Public Health, Phoenix, AZ 85012, USA
192 schema:name Maricopa County Department of Public Health, Phoenix, AZ 85012, USA
193 rdf:type schema:Organization
 




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