Completion of the swine genome will simplify the production of swine as a large animal biomedical model View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-12

AUTHORS

Eric M Walters, Eckhard Wolf, Jeffery J Whyte, Jiude Mao, Simone Renner, Hiroshi Nagashima, Eiji Kobayashi, Jianguo Zhao, Kevin D Wells, John K Critser, Lela K Riley, Randall S Prather

ABSTRACT

BACKGROUND: Anatomic and physiological similarities to the human make swine an excellent large animal model for human health and disease. METHODS: Cloning from a modified somatic cell, which can be determined in cells prior to making the animal, is the only method available for the production of targeted modifications in swine. RESULTS: Since some strains of swine are similar in size to humans, technologies that have been developed for swine can be readily adapted to humans and vice versa. Here the importance of swine as a biomedical model, current technologies to produce genetically enhanced swine, current biomedical models, and how the completion of the swine genome will promote swine as a biomedical model are discussed. CONCLUSIONS: The completion of the swine genome will enhance the continued use and development of swine as models of human health, syndromes and conditions. More... »

PAGES

55

References to SciGraph publications

  • 1996. Sinclair Miniature Swine Melanoma as a Model for Evaluating Novel Lymphography Contrast Agents in ADVANCES IN SWINE IN BIOMEDICAL RESEARCH
  • 2002-03. Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs in NATURE BIOTECHNOLOGY
  • 2011-12. Disruption of the Survival Motor Neuron (SMN) gene in pigs using ssDNA in TRANSGENIC RESEARCH
  • 2011-06. Pig transgenesis by Sleeping Beauty DNA transposition in TRANSGENIC RESEARCH
  • 2010-07. Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer in CELL AND TISSUE RESEARCH
  • 2007-10. Pigs taking wing with transposons and recombinases in GENOME BIOLOGY
  • 1997-03. Infection of human cells by an endogenous retrovirus of pigs in NATURE MEDICINE
  • 2007-12. Enzymatic engineering of the porcine genome with transposons and recombinases in BMC BIOTECHNOLOGY
  • 1981-11. Introduction of a rabbit β-globin gene into the mouse germ line in NATURE
  • 1985-06. Production of transgenic rabbits, sheep and pigs by microinjection in NATURE
  • 2010-07. Transgenic pigs as models for translational biomedical research in JOURNAL OF MOLECULAR MEDICINE
  • 2005-12. Microarray analysis of gene expression profiles of cardiac myocytes and fibroblasts after mechanical stress, ionising or ultraviolet radiation in BMC GENOMICS
  • 2011-02. Recommendations for the design of laboratory studies on non-target arthropods for risk assessment of genetically engineered plants in TRANSGENIC RESEARCH
  • 2007-07. Xenotransplantation: current status and a perspective on the future in NATURE REVIEWS IMMUNOLOGY
  • 2006-08. Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly in NATURE PROTOCOLS
  • 2007-02. Humanized mice in translational biomedical research in NATURE REVIEWS IMMUNOLOGY
  • 2011-06. Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus in TRANSGENIC RESEARCH
  • 2007-03. Incretin mimetics vie for slice of type 2 diabetes market in NATURE BIOTECHNOLOGY
  • 1998-01. Repeat-induced gene silencing in mammals in NATURE GENETICS
  • 2008. Gene Targeting in Drosophila and Caenorhabditis elegans With Zinc-Finger Nucleases in CHROMOSOMAL MUTAGENESIS
  • 2011-06. Targeted disruption of the porcine immunoglobulin kappa light chain locus in TRANSGENIC RESEARCH
  • 1972-06. Of pigs and men and research in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 2011-10. Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system in TRANSGENIC RESEARCH
  • 2011-02. Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition in TRANSGENIC RESEARCH
  • 2010-06. Zinc-finger nucleases: a powerful tool for genetic engineering of animals in TRANSGENIC RESEARCH
  • 2002-04. Efficient Generation of α(1,3) Galactosyltransferase Knockout Porcine Fetal Fibroblasts for Nuclear Transfer in TRANSGENIC RESEARCH
  • 2010-12. Pig genome sequence - analysis and publication strategy in BMC GENOMICS
  • 2009-10. Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays in NATURE PROTOCOLS
  • 2005-12. Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing in BMC GENOMICS
  • 1994-07. Insertional mutagenesis in transgenic mice in TRANSGENIC RESEARCH
  • 2005-06. Highly efficient endogenous human gene correction using designed zinc-finger nucleases in NATURE
  • 2011-06. Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning in CELL RESEARCH
  • 1997-10. Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa in NATURE BIOTECHNOLOGY
  • 2008-12. Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation in MOLECULAR CANCER
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1755-8794-5-55

    DOI

    http://dx.doi.org/10.1186/1755-8794-5-55

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1042464870

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23151353


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