Rapidly reversible multiorgan failure after ingestion of “Molly” (pure 3,4-methylenedioxymethamphetamine): a case report View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Trupti Vakde, Manuel Diaz, Kalpana Uday, Richard Duncalf

ABSTRACT

INTRODUCTION: "Molly" is a street name for pure 3,4-methylenedioxymethamphetamine, an amphetamine derivative which acts by enhancing the release of neurotransmitters such as serotonin, dopamine and norepinephrine. This produces euphoria, increased sensory awareness and central stimulation that make it a popular club drug. Nevertheless, it is also associated with serious side effects. We report an unusual case of rapid multiorgan failure after ingestion of "Molly". Unlike previously described patterns of 3,4-methylenedioxymethamphetamine-related organ failure, our case does not appear to be related to hyperthermia, rhabdomyolysis or hyponatremia. CASE PRESENTATION: A 24-year-old Hispanic man presented to our hospital with an episode of seizure and subsequently developed acute kidney injury, respiratory failure requiring mechanical ventilation and congestive heart failure after ingestion of "Molly". He rapidly recovered with supportive care and was discharged home. CONCLUSIONS: The spectrum of complications associated with 3,4-methylenedioxymethamphetamine is wide and patient presentation may vary. Moreover, there appears to be multiple mechanisms involved in organ failure. Drug toxicity should be suspected while evaluating a patient with multisystem organ failure of unclear etiology. Treatment is generally supportive sometimes requiring mechanical ventilation and hemodialysis. Nevertheless, complete reversal of organ failure can be expected. More... »

PAGES

204

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1752-1947-8-204

DOI

http://dx.doi.org/10.1186/1752-1947-8-204

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035048357

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24942782


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