Translation of SBGN maps: Process Description to Activity Flow View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Torsten Vogt, Tobias Czauderna, Falk Schreiber

ABSTRACT

BACKGROUND: The Systems Biology Graphical Notation (SBGN) provides standard graphical languages for representing cellular processes, interactions, and biological networks. SBGN consists of three languages: Process Descriptions (PD), Entity Relationships (ER), and Activity Flows (AF). Maps in SBGN PD are often large, detailed, and complex, therefore there is a need for a simplified illustration. RESULTS: To solve this problem we define translations of SBGN PD maps into the more abstract SBGN AF maps. We present a template-based translation which allows the user to focus on different aspects of the underlying biological system. We also discuss aspects of laying out the AF map and of interactive navigation between both the PD and the AF map. The methods developed here have been implemented as part of SBGN-ED ( http://www.sbgn-ed.org). CONCLUSIONS: SBGN PD maps become much smaller and more manageable when translated into SBGN AF. The flexible translation of PD into AF and related interaction methods are an initial step in translating the different SBGN languages and open the path to future research for translation methods between other SBGN languages. More... »

PAGES

115

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1752-0509-7-115

DOI

http://dx.doi.org/10.1186/1752-0509-7-115

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043005395

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24176088


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