Peripheral doses in patients undergoing Cyberknife treatment for intracranial lesions. A single centre experience View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-11-14

AUTHORS

Vassiliki Vlachopoulou, Christos Antypas, Harry Delis, Argyrios Tzouras, Nikolaos Salvaras, Dimitrios Kardamakis, George Panayiotakis

ABSTRACT

BACKGROUND: Stereotactic radiosurgery/radiotherapy procedures are known to deliver a very high dose per fraction, and thus, the corresponding peripheral dose could be a limiting factor for the long term surviving patients. The aim of this clinical study was to measure the peripheral dose delivered to patients undergoing intracranial Cyberknife treatment, using the MOSFET dosimeters. The influence of the supplemental shielding, the number of monitor units and the collimator size to the peripheral dose were investigated. METHODS: MOSFET dosimeters were placed in preselected anatomical regions of the patient undergoing Cyberknife treatment, namely the thyroid gland, the nipple, the umbilicus and the pubic symphysis. RESULTS: The mean peripheral doses before the supplemental shielding was added to the Cyberknife unit were 51.79 cGy, 13.31 cGy and 10.07 cGy while after the shielding upgrade they were 38.40 cGy, 10.94 cGy, and 8.69 cGy, in the thyroid gland, the umbilicus and the pubic symphysis, respectively. The increase of the collimator size corresponds to an increase of the PD and becomes less significant at larger distances, indicating that at these distances the PD is predominate due to the head leakage and collimator scatter. CONCLUSION: Weighting the effect of the number of monitor units and the collimator size can be effectively used during the optimization procedure in order to choose the most suitable treatment plan that will deliver the maximum dose to the tumor, while being compatible with the dose constraints for the surrounding organs at risk. Attention is required in defining the thyroid gland as a structure of avoidance in the treatment plan especially in patients with benign diseases. More... »

PAGES

157-157

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1748-717x-6-157

DOI

http://dx.doi.org/10.1186/1748-717x-6-157

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041823709

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22082279


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