Ontology type: schema:ScholarlyArticle Open Access: True
2013-02-27
AUTHORSFaruk Skenderi, Fikreta Krakonja, Semir Vranic
ABSTRACTIntroductionFibroadenomas are the most common benign breast tumors in young women. Infarction is rarely observed in fibroadenomas and when present, it is usually associated with pregnancy or lactation. Infarction can exceptionally occur as a complication of previous fine-needle aspiration biopsy or during lactation and pregnancy.Materials and methodsRetrospective review of 650 cases of fibroadenomas diagnosed at our institution during the 8-years period identified two cases of fibroadenomas with infarction (rate ~0.3%).ResultsTwo partially infarcted fibroadenomas were diagnosed on core biopsy and frozen section in an adolescent girl (13 years old) and in a young woman (25 years old), respectively. No preceding fine-needle aspiration biopsy was performed in these cases, nor were the patients pregnant or lactating at the time of the diagnosis.ConclusionSpontaneous infarction within fibroadenoma is a rare phenomenon in younger patients. The presence of necrosis on core biopsy or frozen section should be cautiously interpreted and is not a sign of malignancy.Virtual SlidesThe virtual slide(s) for this article can be found here:http://www.diagnosticpathology.diagnomx.eu/vs/1556060549847356 More... »
PAGES38
http://scigraph.springernature.com/pub.10.1186/1746-1596-8-38
DOIhttp://dx.doi.org/10.1186/1746-1596-8-38
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/23445683
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