A feasibility study examining the effect on lung cancer diagnosis of offering a chest X-ray to higher-risk patients with chest ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Christopher N Hurt, Kirsty Roberts, Trevor K Rogers, Gareth O Griffiths, Kerry Hood, Hayley Prout, Annmarie Nelson, Jim Fitzgibbon, Allan Barham, Emma Thomas-Jones, Rhiannon Tudor Edwards, Seow Tien Yeo, William Hamilton, Angela Tod, Richard D Neal

ABSTRACT

BACKGROUND: In order to improve lung cancer survival in the UK, a greater proportion of resectable cancers must be diagnosed. It is likely that resectability rates would be increased by more timely diagnosis. Aside from screening, the only way of achieving this is to reduce the time to diagnosis in symptomatic cancers. Currently, lung cancers are mainly diagnosed by general practitioners (GPs) using the National Institute for Health and Clinical Excellence (NICE) guidelines for urgent referral for chest X-ray, which recommend urgent imaging or referral for patients who have one of a number of chest symptoms for more than 3 weeks. We are proposing to expand this recommendation to include one of a number of chest symptoms of any duration in higher-risk patients. METHODS/DESIGN: We intend to conduct a trial of imaging in these higher-risk patients and compare it with NICE guidelines to see if imaging improves stage at diagnosis and resection rates. This trial would have to be large (and consequently resource-intensive) because most of these patients will not have lung cancer, making optimal design crucial. We are therefore conducting a pilot trial that will ascertain the feasibility of running a full trial and provide key information that will be required in order to design the full trial. DISCUSSION: This trial will assess the feasibility and inform the design of a large, UK-wide, clinical trial of a change to the NICE guidelines for urgent referral for chest X-ray for suspected lung cancer. It utilizes a combination of workshop, health economic, quality of life, qualitative, and quantitative methods in order to fully assess feasibility. TRIAL REGISTRATION: Clinicaltrials.gov NCT01344005. More... »

PAGES

405

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1745-6215-14-405

DOI

http://dx.doi.org/10.1186/1745-6215-14-405

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018707395

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24279296


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