Improving delirium care in the intensive care unit: The design of a pragmatic study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-12

AUTHORS

Noll L Campbell, Babar A Khan, Mark Farber, Tiffany Campbell, Anthony J Perkins, Siu L Hui, Greg Abernathy, John Buckley, Regg Sing, Jason Tricker, Mohammad Zawahiri, Malaz A Boustani

ABSTRACT

BACKGROUND: Delirium prevalence in the intensive care unit (ICU) is high. Numerous psychotropic agents are used to manage delirium in the ICU with limited data regarding their efficacy or harms. METHODS/DESIGN: This is a randomized controlled trial of 428 patients aged 18 and older suffering from delirium and admitted to the ICU of Wishard Memorial Hospital in Indianapolis. Subjects assigned to the intervention group will receive a multicomponent pharmacological management protocol for delirium (PMD) and those assigned to the control group will receive no change in their usual ICU care. The primary outcomes of the trial are (1) delirium severity as measured by the Delirium Rating Scale revised-98 (DRS-R-98) and (2) delirium duration as determined by the Confusion Assessment Method for the ICU (CAM-ICU). The PMD protocol targets the three neurotransmitter systems thought to be compromised in delirious patients: dopamine, acetylcholine, and gamma-aminobutyric acid. The PMD protocol will target the reduction of anticholinergic medications and benzodiazepines, and introduce a low-dose of haloperidol at 0.5-1 mg for 7 days. The protocol will be delivered by a combination of computer (artificial intelligence) and pharmacist (human intelligence) decision support system to increase adherence to the PMD protocol. DISCUSSION: The proposed study will evaluate the content and the delivery process of a multicomponent pharmacological management program for delirium in the ICU. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00842608. More... »

PAGES

139

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1745-6215-12-139

DOI

http://dx.doi.org/10.1186/1745-6215-12-139

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025677904

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21645330


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Artificial Intelligence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Benzodiazepines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholinergic Antagonists", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Critical Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Decision Support Systems, Clinical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Delirium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Therapy, Combination", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haloperidol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hospital Mortality", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Indiana", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intensive Care Units", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Length of Stay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Medical Order Entry Systems", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Psychiatric Status Rating Scales", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Psychotropic Drugs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality Improvement", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Research Design", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Severity of Illness Index", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Indiana University Health", 
          "id": "https://www.grid.ac/institutes/grid.411569.e", 
          "name": [
            "Department of Pharmacy Practice, Purdue University School of Pharmacy, West Lafayette, IN, USA", 
            "Indiana University Center for Aging Research, Indianapolis, IN, USA", 
            "Regenstrief Institute, Inc., Indianapolis, IN, USA", 
            "Wishard Health Services, Indianapolis, IN, USA", 
            "Indiana University Health, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campbell", 
        "givenName": "Noll L", 
        "id": "sg:person.0654062501.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654062501.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khan", 
        "givenName": "Babar A", 
        "id": "sg:person.01012364736.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012364736.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Richard L. Roudebush VA Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.280828.8", 
          "name": [
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA", 
            "Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Farber", 
        "givenName": "Mark", 
        "id": "sg:person.01027406060.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027406060.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Regenstrief Institute", 
          "id": "https://www.grid.ac/institutes/grid.448342.d", 
          "name": [
            "Regenstrief Institute, Inc., Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campbell", 
        "givenName": "Tiffany", 
        "id": "sg:person.01132454436.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132454436.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Regenstrief Institute", 
          "id": "https://www.grid.ac/institutes/grid.448342.d", 
          "name": [
            "Regenstrief Institute, Inc., Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Perkins", 
        "givenName": "Anthony J", 
        "id": "sg:person.0653267515.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653267515.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Indiana University Center for Aging Research, Indianapolis, IN, USA", 
            "Regenstrief Institute, Inc., Indianapolis, IN, USA", 
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hui", 
        "givenName": "Siu L", 
        "id": "sg:person.010414552502.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010414552502.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Regenstrief Institute, Inc., Indianapolis, IN, USA", 
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abernathy", 
        "givenName": "Greg", 
        "id": "sg:person.01042372204.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042372204.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Buckley", 
        "givenName": "John", 
        "id": "sg:person.01363131436.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363131436.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sing", 
        "givenName": "Regg", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wishard Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.417143.4", 
          "name": [
            "Wishard Health Services, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tricker", 
        "givenName": "Jason", 
        "id": "sg:person.01152652701.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152652701.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Regenstrief Institute", 
          "id": "https://www.grid.ac/institutes/grid.448342.d", 
          "name": [
            "Regenstrief Institute, Inc., Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zawahiri", 
        "givenName": "Mohammad", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
          "id": "https://www.grid.ac/institutes/grid.257413.6", 
          "name": [
            "Indiana University Center for Aging Research, Indianapolis, IN, USA", 
            "Regenstrief Institute, Inc., Indianapolis, IN, USA", 
            "Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boustani", 
        "givenName": "Malaz A", 
        "id": "sg:person.0605747301.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605747301.01"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/gerona/61.12.1281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000846048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1041610204000390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003616320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1041610204000390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003616320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmsa010181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004280910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra052321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004878770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccc.2007.10.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006791120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.289.22.2983", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007223166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-001-1132-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010248409", 
          "https://doi.org/10.1007/s00134-001-1132-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1444-0903.2004.00549.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013197988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.2107138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013441079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1993.03500240063027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014612948"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.163.22.2716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015418416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000146301.47334.bd", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016954307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000146301.47334.bd", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016954307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000146301.47334.bd", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016954307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jhm.691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017068726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jhm.691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017068726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2010.1013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019197250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccc.2007.07.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019241071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0021-9681(87)90171-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020988115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.286.21.2703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023293188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-198108000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024196548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-198108000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024196548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-198108000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024196548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000098033.94737.84", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024732733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000098033.94737.84", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024732733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.130.3.869", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024927161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200201000-00020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025932689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200201000-00020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025932689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2217/1745509x.4.3.311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028810673"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000542-200601000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029417168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000542-200601000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029417168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000542-200601000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029417168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-1781(88)90037-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029661976"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030818397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030818397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000095463.72353.ad", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032842113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000095463.72353.ad", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032842113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.298.22.2644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036794230"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/61.12.1277", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037877947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0447.1970.tb02066.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038841887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:nerv.0000028080.39602.17", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039840482", 
          "https://doi.org/10.1023/b:nerv.0000028080.39602.17"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-032303930-7.50023-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040626366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11606-009-0996-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043361147", 
          "https://doi.org/10.1007/s11606-009-0996-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11606-009-0996-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043361147", 
          "https://doi.org/10.1007/s11606-009-0996-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1176/appi.psy.45.3.235", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044175890"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jhm.589", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045346700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jhm.589", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045346700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.269.24.3119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054155631"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1176/ajp.153.2.231", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063484309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1176/jnp.13.2.229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063511770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1176/jnp.14.2.167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063511865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1192/bjp.154.5.672", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064170005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2146/ajhp090181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069099354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2146/ajhp090181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069099354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2146/ajhp090181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069099354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-135-8_part_2-200110161-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073705163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074458926", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074648241", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075177721", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077241887", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077525444", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077687981", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-12", 
    "datePublishedReg": "2011-12-01", 
    "description": "BACKGROUND: Delirium prevalence in the intensive care unit (ICU) is high. Numerous psychotropic agents are used to manage delirium in the ICU with limited data regarding their efficacy or harms.\nMETHODS/DESIGN: This is a randomized controlled trial of 428 patients aged 18 and older suffering from delirium and admitted to the ICU of Wishard Memorial Hospital in Indianapolis. Subjects assigned to the intervention group will receive a multicomponent pharmacological management protocol for delirium (PMD) and those assigned to the control group will receive no change in their usual ICU care. The primary outcomes of the trial are (1) delirium severity as measured by the Delirium Rating Scale revised-98 (DRS-R-98) and (2) delirium duration as determined by the Confusion Assessment Method for the ICU (CAM-ICU). The PMD protocol targets the three neurotransmitter systems thought to be compromised in delirious patients: dopamine, acetylcholine, and gamma-aminobutyric acid. The PMD protocol will target the reduction of anticholinergic medications and benzodiazepines, and introduce a low-dose of haloperidol at 0.5-1 mg for 7 days. The protocol will be delivered by a combination of computer (artificial intelligence) and pharmacist (human intelligence) decision support system to increase adherence to the PMD protocol.\nDISCUSSION: The proposed study will evaluate the content and the delivery process of a multicomponent pharmacological management program for delirium in the ICU.\nTRIAL REGISTRATION: ClinicalTrials.gov: NCT00842608.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1745-6215-12-139", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2448603", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1297400", 
        "issn": [
          "1468-6708", 
          "1745-6215"
        ], 
        "name": "Trials", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "12"
      }
    ], 
    "name": "Improving delirium care in the intensive care unit: The design of a pragmatic study", 
    "pagination": "139", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7a54b23488706f6be3599d77eeca06efcb7cd5d3f00c9b2f191056f088cc36d6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21645330"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101263253"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1745-6215-12-139"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1025677904"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1745-6215-12-139", 
      "https://app.dimensions.ai/details/publication/pub.1025677904"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000550.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1745-6215-12-139"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1745-6215-12-139'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1745-6215-12-139'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1745-6215-12-139'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1745-6215-12-139'


 

This table displays all metadata directly associated to this object as RDF triples.

407 TRIPLES      21 PREDICATES      102 URIs      47 LITERALS      35 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1745-6215-12-139 schema:about N0a5e8a25f31446bcb8de80b9a16c7796
2 N243af25132884692ba98197646de09af
3 N2c6f69d25f1040669e13a8d6716e64af
4 N34d80ab3fa8740b1bba6fb56683386e7
5 N3c0fa32e37914e3180a0ea7c3df5f790
6 N3c5dceb30288416e96c8ab07f745972b
7 N44e4eb3ceff74fbba49184bfbf647c68
8 N4ae72085896244b887283bf9eaaea69d
9 N55c5a714693040b1ade0bb1318b0fd2f
10 N640091de338849ffa12eded555fd8156
11 N69b0c9d6254f4b15b8d38139d037a022
12 N7ef23aa516b74a428e736675028bf9e4
13 N81f2f06fd30146b3a559082e6f8773dc
14 N929109e55b214529953afaa82da627a8
15 N93037d9acc5c4b8ebc6e9074b58e91ff
16 Na4fca4e938d541d0b0fe7d9df1de9c29
17 Nac0d4697dde846c9bc845d20b959d9f3
18 Nae5f8e1d4b284d83bce36ead47c7f171
19 Naf7bc0694fe7468796e35fac399c005b
20 Nb43c46bda3e44e89a3b1866368c343e8
21 Nb599c501a762495aa10f2229ca566d54
22 Nb9899ef71c514bc1a5193bb287a2cbaf
23 Nbb9a3199411d474db821e0ae2a72c1f7
24 Nef5189dd0ec744ffbc40cabe6eb6e16d
25 Nf54c6cfbfd6e4ec691199efd1d63c79e
26 Nf69172d6bd4e40c4b6953bae6fb98041
27 anzsrc-for:11
28 anzsrc-for:1103
29 schema:author Ndbb675c19f4642229ac0825b31ca45be
30 schema:citation sg:pub.10.1007/s00134-001-1132-2
31 sg:pub.10.1007/s11606-009-0996-7
32 sg:pub.10.1023/b:nerv.0000028080.39602.17
33 https://app.dimensions.ai/details/publication/pub.1074458926
34 https://app.dimensions.ai/details/publication/pub.1074648241
35 https://app.dimensions.ai/details/publication/pub.1075177721
36 https://app.dimensions.ai/details/publication/pub.1077241887
37 https://app.dimensions.ai/details/publication/pub.1077525444
38 https://app.dimensions.ai/details/publication/pub.1077687981
39 https://doi.org/10.1001/archinte.163.22.2716
40 https://doi.org/10.1001/jama.1993.03500240063027
41 https://doi.org/10.1001/jama.2010.1013
42 https://doi.org/10.1001/jama.269.24.3119
43 https://doi.org/10.1001/jama.286.21.2703
44 https://doi.org/10.1001/jama.289.22.2983
45 https://doi.org/10.1001/jama.298.22.2644
46 https://doi.org/10.1002/jhm.589
47 https://doi.org/10.1002/jhm.691
48 https://doi.org/10.1016/0021-9681(87)90171-8
49 https://doi.org/10.1016/0165-1781(88)90037-6
50 https://doi.org/10.1016/b978-032303930-7.50023-7
51 https://doi.org/10.1016/j.ccc.2007.07.001
52 https://doi.org/10.1016/j.ccc.2007.10.002
53 https://doi.org/10.1017/s1041610204000390
54 https://doi.org/10.1056/nejmra052321
55 https://doi.org/10.1056/nejmsa010181
56 https://doi.org/10.1093/gerona/61.12.1277
57 https://doi.org/10.1093/gerona/61.12.1281
58 https://doi.org/10.1097/00000542-200601000-00005
59 https://doi.org/10.1097/00003246-198108000-00008
60 https://doi.org/10.1097/00003246-200107000-00012
61 https://doi.org/10.1097/00003246-200201000-00020
62 https://doi.org/10.1097/01.ccm.0000095463.72353.ad
63 https://doi.org/10.1097/01.ccm.0000098033.94737.84
64 https://doi.org/10.1097/01.ccm.0000146301.47334.bd
65 https://doi.org/10.1111/j.1444-0903.2004.00549.x
66 https://doi.org/10.1111/j.1600-0447.1970.tb02066.x
67 https://doi.org/10.1164/rccm.2107138
68 https://doi.org/10.1176/ajp.153.2.231
69 https://doi.org/10.1176/appi.psy.45.3.235
70 https://doi.org/10.1176/jnp.13.2.229
71 https://doi.org/10.1176/jnp.14.2.167
72 https://doi.org/10.1192/bjp.154.5.672
73 https://doi.org/10.1378/chest.130.3.869
74 https://doi.org/10.2146/ajhp090181
75 https://doi.org/10.2217/1745509x.4.3.311
76 https://doi.org/10.7326/0003-4819-135-8_part_2-200110161-00005
77 schema:datePublished 2011-12
78 schema:datePublishedReg 2011-12-01
79 schema:description BACKGROUND: Delirium prevalence in the intensive care unit (ICU) is high. Numerous psychotropic agents are used to manage delirium in the ICU with limited data regarding their efficacy or harms. METHODS/DESIGN: This is a randomized controlled trial of 428 patients aged 18 and older suffering from delirium and admitted to the ICU of Wishard Memorial Hospital in Indianapolis. Subjects assigned to the intervention group will receive a multicomponent pharmacological management protocol for delirium (PMD) and those assigned to the control group will receive no change in their usual ICU care. The primary outcomes of the trial are (1) delirium severity as measured by the Delirium Rating Scale revised-98 (DRS-R-98) and (2) delirium duration as determined by the Confusion Assessment Method for the ICU (CAM-ICU). The PMD protocol targets the three neurotransmitter systems thought to be compromised in delirious patients: dopamine, acetylcholine, and gamma-aminobutyric acid. The PMD protocol will target the reduction of anticholinergic medications and benzodiazepines, and introduce a low-dose of haloperidol at 0.5-1 mg for 7 days. The protocol will be delivered by a combination of computer (artificial intelligence) and pharmacist (human intelligence) decision support system to increase adherence to the PMD protocol. DISCUSSION: The proposed study will evaluate the content and the delivery process of a multicomponent pharmacological management program for delirium in the ICU. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00842608.
80 schema:genre research_article
81 schema:inLanguage en
82 schema:isAccessibleForFree true
83 schema:isPartOf N2d0b985d57d348d79713f8f1bf8abb1c
84 N77c548becf924ab0bcc76041079402fb
85 sg:journal.1297400
86 schema:name Improving delirium care in the intensive care unit: The design of a pragmatic study
87 schema:pagination 139
88 schema:productId Nc62a6a4ce6aa40b39975345d15af7cfe
89 Nc7a2109439904a8f9bf7b9f80a28b6fd
90 Nefe9f0438fcf49a8b56fe49e8fca46ea
91 Nf34007fc10a44d5b8cb09df715cc472a
92 Nf42a9d23777e49e5bd2a39e04b8640be
93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025677904
94 https://doi.org/10.1186/1745-6215-12-139
95 schema:sdDatePublished 2019-04-10T18:26
96 schema:sdLicense https://scigraph.springernature.com/explorer/license/
97 schema:sdPublisher Nf8832afd096e479299b132e373232666
98 schema:url http://link.springer.com/10.1186%2F1745-6215-12-139
99 sgo:license sg:explorer/license/
100 sgo:sdDataset articles
101 rdf:type schema:ScholarlyArticle
102 N040b859006c44d868ad0d3def4fb1888 rdf:first sg:person.01042372204.36
103 rdf:rest Nd8b0811abef7447da787300cdc669e44
104 N0a5e8a25f31446bcb8de80b9a16c7796 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Critical Care
106 rdf:type schema:DefinedTerm
107 N243af25132884692ba98197646de09af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Hospital Mortality
109 rdf:type schema:DefinedTerm
110 N2c6f69d25f1040669e13a8d6716e64af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Time Factors
112 rdf:type schema:DefinedTerm
113 N2c7c9c8212094132ae3b10d31500c49d rdf:first sg:person.01027406060.67
114 rdf:rest N770f5c8909c347c3bbf974d4e2a53a3c
115 N2d0b985d57d348d79713f8f1bf8abb1c schema:volumeNumber 12
116 rdf:type schema:PublicationVolume
117 N34d80ab3fa8740b1bba6fb56683386e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Humans
119 rdf:type schema:DefinedTerm
120 N3c0fa32e37914e3180a0ea7c3df5f790 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Artificial Intelligence
122 rdf:type schema:DefinedTerm
123 N3c5dceb30288416e96c8ab07f745972b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Length of Stay
125 rdf:type schema:DefinedTerm
126 N40771b5af018416f84448ba37f4ff7aa rdf:first sg:person.010414552502.11
127 rdf:rest N040b859006c44d868ad0d3def4fb1888
128 N44e4eb3ceff74fbba49184bfbf647c68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Male
130 rdf:type schema:DefinedTerm
131 N4ae72085896244b887283bf9eaaea69d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Severity of Illness Index
133 rdf:type schema:DefinedTerm
134 N4db9b14fa65e4a2ea32375baa0b0cd64 rdf:first sg:person.01152652701.83
135 rdf:rest N54a0c06410ae443fbf749eb9c6859900
136 N54a0c06410ae443fbf749eb9c6859900 rdf:first N7b3d3b70a832409eb001ec5453db2be8
137 rdf:rest Nce51bb60cce8423e94094c03b22b192b
138 N55c5a714693040b1ade0bb1318b0fd2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Psychiatric Status Rating Scales
140 rdf:type schema:DefinedTerm
141 N5fe02f7c5b6541c9911f5253ae105dac rdf:first sg:person.01012364736.13
142 rdf:rest N2c7c9c8212094132ae3b10d31500c49d
143 N640091de338849ffa12eded555fd8156 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Decision Support Systems, Clinical
145 rdf:type schema:DefinedTerm
146 N69b0c9d6254f4b15b8d38139d037a022 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Benzodiazepines
148 rdf:type schema:DefinedTerm
149 N770f5c8909c347c3bbf974d4e2a53a3c rdf:first sg:person.01132454436.35
150 rdf:rest Nb54b420c1aca431a986c5fded309c514
151 N77c548becf924ab0bcc76041079402fb schema:issueNumber 1
152 rdf:type schema:PublicationIssue
153 N7b3d3b70a832409eb001ec5453db2be8 schema:affiliation https://www.grid.ac/institutes/grid.448342.d
154 schema:familyName Zawahiri
155 schema:givenName Mohammad
156 rdf:type schema:Person
157 N7ef23aa516b74a428e736675028bf9e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Research Design
159 rdf:type schema:DefinedTerm
160 N81f2f06fd30146b3a559082e6f8773dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Middle Aged
162 rdf:type schema:DefinedTerm
163 N929109e55b214529953afaa82da627a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Psychotropic Drugs
165 rdf:type schema:DefinedTerm
166 N93037d9acc5c4b8ebc6e9074b58e91ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Drug Therapy, Combination
168 rdf:type schema:DefinedTerm
169 Na4fca4e938d541d0b0fe7d9df1de9c29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Female
171 rdf:type schema:DefinedTerm
172 Nac0d4697dde846c9bc845d20b959d9f3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Aged
174 rdf:type schema:DefinedTerm
175 Nae5f8e1d4b284d83bce36ead47c7f171 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Indiana
177 rdf:type schema:DefinedTerm
178 Naf7bc0694fe7468796e35fac399c005b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Delirium
180 rdf:type schema:DefinedTerm
181 Nb43c46bda3e44e89a3b1866368c343e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Haloperidol
183 rdf:type schema:DefinedTerm
184 Nb54b420c1aca431a986c5fded309c514 rdf:first sg:person.0653267515.30
185 rdf:rest N40771b5af018416f84448ba37f4ff7aa
186 Nb599c501a762495aa10f2229ca566d54 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Cholinergic Antagonists
188 rdf:type schema:DefinedTerm
189 Nb9899ef71c514bc1a5193bb287a2cbaf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Treatment Outcome
191 rdf:type schema:DefinedTerm
192 Nbb9a3199411d474db821e0ae2a72c1f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Aged, 80 and over
194 rdf:type schema:DefinedTerm
195 Nc62a6a4ce6aa40b39975345d15af7cfe schema:name doi
196 schema:value 10.1186/1745-6215-12-139
197 rdf:type schema:PropertyValue
198 Nc7a2109439904a8f9bf7b9f80a28b6fd schema:name nlm_unique_id
199 schema:value 101263253
200 rdf:type schema:PropertyValue
201 Nce51bb60cce8423e94094c03b22b192b rdf:first sg:person.0605747301.01
202 rdf:rest rdf:nil
203 Nd8b0811abef7447da787300cdc669e44 rdf:first sg:person.01363131436.27
204 rdf:rest Ndc6d8aede66742bca618615858c9d201
205 Ndb427cd8d7504cdbb31903b14d96b179 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
206 schema:familyName Sing
207 schema:givenName Regg
208 rdf:type schema:Person
209 Ndbb675c19f4642229ac0825b31ca45be rdf:first sg:person.0654062501.15
210 rdf:rest N5fe02f7c5b6541c9911f5253ae105dac
211 Ndc6d8aede66742bca618615858c9d201 rdf:first Ndb427cd8d7504cdbb31903b14d96b179
212 rdf:rest N4db9b14fa65e4a2ea32375baa0b0cd64
213 Nef5189dd0ec744ffbc40cabe6eb6e16d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
214 schema:name Medical Order Entry Systems
215 rdf:type schema:DefinedTerm
216 Nefe9f0438fcf49a8b56fe49e8fca46ea schema:name dimensions_id
217 schema:value pub.1025677904
218 rdf:type schema:PropertyValue
219 Nf34007fc10a44d5b8cb09df715cc472a schema:name pubmed_id
220 schema:value 21645330
221 rdf:type schema:PropertyValue
222 Nf42a9d23777e49e5bd2a39e04b8640be schema:name readcube_id
223 schema:value 7a54b23488706f6be3599d77eeca06efcb7cd5d3f00c9b2f191056f088cc36d6
224 rdf:type schema:PropertyValue
225 Nf54c6cfbfd6e4ec691199efd1d63c79e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
226 schema:name Quality Improvement
227 rdf:type schema:DefinedTerm
228 Nf69172d6bd4e40c4b6953bae6fb98041 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
229 schema:name Intensive Care Units
230 rdf:type schema:DefinedTerm
231 Nf8832afd096e479299b132e373232666 schema:name Springer Nature - SN SciGraph project
232 rdf:type schema:Organization
233 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
234 schema:name Medical and Health Sciences
235 rdf:type schema:DefinedTerm
236 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
237 schema:name Clinical Sciences
238 rdf:type schema:DefinedTerm
239 sg:grant.2448603 http://pending.schema.org/fundedItem sg:pub.10.1186/1745-6215-12-139
240 rdf:type schema:MonetaryGrant
241 sg:journal.1297400 schema:issn 1468-6708
242 1745-6215
243 schema:name Trials
244 rdf:type schema:Periodical
245 sg:person.01012364736.13 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
246 schema:familyName Khan
247 schema:givenName Babar A
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012364736.13
249 rdf:type schema:Person
250 sg:person.01027406060.67 schema:affiliation https://www.grid.ac/institutes/grid.280828.8
251 schema:familyName Farber
252 schema:givenName Mark
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027406060.67
254 rdf:type schema:Person
255 sg:person.010414552502.11 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
256 schema:familyName Hui
257 schema:givenName Siu L
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010414552502.11
259 rdf:type schema:Person
260 sg:person.01042372204.36 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
261 schema:familyName Abernathy
262 schema:givenName Greg
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042372204.36
264 rdf:type schema:Person
265 sg:person.01132454436.35 schema:affiliation https://www.grid.ac/institutes/grid.448342.d
266 schema:familyName Campbell
267 schema:givenName Tiffany
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132454436.35
269 rdf:type schema:Person
270 sg:person.01152652701.83 schema:affiliation https://www.grid.ac/institutes/grid.417143.4
271 schema:familyName Tricker
272 schema:givenName Jason
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152652701.83
274 rdf:type schema:Person
275 sg:person.01363131436.27 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
276 schema:familyName Buckley
277 schema:givenName John
278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363131436.27
279 rdf:type schema:Person
280 sg:person.0605747301.01 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
281 schema:familyName Boustani
282 schema:givenName Malaz A
283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605747301.01
284 rdf:type schema:Person
285 sg:person.0653267515.30 schema:affiliation https://www.grid.ac/institutes/grid.448342.d
286 schema:familyName Perkins
287 schema:givenName Anthony J
288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653267515.30
289 rdf:type schema:Person
290 sg:person.0654062501.15 schema:affiliation https://www.grid.ac/institutes/grid.411569.e
291 schema:familyName Campbell
292 schema:givenName Noll L
293 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654062501.15
294 rdf:type schema:Person
295 sg:pub.10.1007/s00134-001-1132-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010248409
296 https://doi.org/10.1007/s00134-001-1132-2
297 rdf:type schema:CreativeWork
298 sg:pub.10.1007/s11606-009-0996-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043361147
299 https://doi.org/10.1007/s11606-009-0996-7
300 rdf:type schema:CreativeWork
301 sg:pub.10.1023/b:nerv.0000028080.39602.17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039840482
302 https://doi.org/10.1023/b:nerv.0000028080.39602.17
303 rdf:type schema:CreativeWork
304 https://app.dimensions.ai/details/publication/pub.1074458926 schema:CreativeWork
305 https://app.dimensions.ai/details/publication/pub.1074648241 schema:CreativeWork
306 https://app.dimensions.ai/details/publication/pub.1075177721 schema:CreativeWork
307 https://app.dimensions.ai/details/publication/pub.1077241887 schema:CreativeWork
308 https://app.dimensions.ai/details/publication/pub.1077525444 schema:CreativeWork
309 https://app.dimensions.ai/details/publication/pub.1077687981 schema:CreativeWork
310 https://doi.org/10.1001/archinte.163.22.2716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015418416
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1001/jama.1993.03500240063027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014612948
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1001/jama.2010.1013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019197250
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1001/jama.269.24.3119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054155631
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1001/jama.286.21.2703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023293188
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1001/jama.289.22.2983 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007223166
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1001/jama.298.22.2644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036794230
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1002/jhm.589 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045346700
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1002/jhm.691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017068726
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/0021-9681(87)90171-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020988115
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1016/0165-1781(88)90037-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029661976
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1016/b978-032303930-7.50023-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040626366
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1016/j.ccc.2007.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019241071
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1016/j.ccc.2007.10.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006791120
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1017/s1041610204000390 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003616320
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1056/nejmra052321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004878770
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1056/nejmsa010181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004280910
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1093/gerona/61.12.1277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037877947
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1093/gerona/61.12.1281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000846048
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1097/00000542-200601000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029417168
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1097/00003246-198108000-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024196548
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1097/00003246-200107000-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030818397
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1097/00003246-200201000-00020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025932689
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1097/01.ccm.0000095463.72353.ad schema:sameAs https://app.dimensions.ai/details/publication/pub.1032842113
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1097/01.ccm.0000098033.94737.84 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024732733
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1097/01.ccm.0000146301.47334.bd schema:sameAs https://app.dimensions.ai/details/publication/pub.1016954307
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1111/j.1444-0903.2004.00549.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013197988
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1111/j.1600-0447.1970.tb02066.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038841887
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1164/rccm.2107138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013441079
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1176/ajp.153.2.231 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063484309
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1176/appi.psy.45.3.235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044175890
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1176/jnp.13.2.229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063511770
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1176/jnp.14.2.167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063511865
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1192/bjp.154.5.672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064170005
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1378/chest.130.3.869 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024927161
379 rdf:type schema:CreativeWork
380 https://doi.org/10.2146/ajhp090181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069099354
381 rdf:type schema:CreativeWork
382 https://doi.org/10.2217/1745509x.4.3.311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028810673
383 rdf:type schema:CreativeWork
384 https://doi.org/10.7326/0003-4819-135-8_part_2-200110161-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073705163
385 rdf:type schema:CreativeWork
386 https://www.grid.ac/institutes/grid.257413.6 schema:alternateName Indiana University – Purdue University Indianapolis
387 schema:name Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
388 Indiana University Center for Aging Research, Indianapolis, IN, USA
389 Regenstrief Institute, Inc., Indianapolis, IN, USA
390 rdf:type schema:Organization
391 https://www.grid.ac/institutes/grid.280828.8 schema:alternateName Richard L. Roudebush VA Medical Center
392 schema:name Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
393 Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, IN, USA
394 rdf:type schema:Organization
395 https://www.grid.ac/institutes/grid.411569.e schema:alternateName Indiana University Health
396 schema:name Department of Pharmacy Practice, Purdue University School of Pharmacy, West Lafayette, IN, USA
397 Indiana University Center for Aging Research, Indianapolis, IN, USA
398 Indiana University Health, Indianapolis, IN, USA
399 Regenstrief Institute, Inc., Indianapolis, IN, USA
400 Wishard Health Services, Indianapolis, IN, USA
401 rdf:type schema:Organization
402 https://www.grid.ac/institutes/grid.417143.4 schema:alternateName Wishard Memorial Hospital
403 schema:name Wishard Health Services, Indianapolis, IN, USA
404 rdf:type schema:Organization
405 https://www.grid.ac/institutes/grid.448342.d schema:alternateName Regenstrief Institute
406 schema:name Regenstrief Institute, Inc., Indianapolis, IN, USA
407 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...