The role of thallium-201 and pentavalent dimercaptosuccinic acid for staging cartilaginous tumours View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2004-12

AUTHORS

Peter FM Choong, Toshiyuki Kunisada, John Slavin, Stephen Schlicht, Rodney Hicks

ABSTRACT

INTRODUCTION: Heterogeneity of cartilage tumours may confound accurate diagnosis and grading resulting in under and over treatment. Improved preoperative assessment of malignancy and grade would be invaluable for developing a rational plan for treatment. We examined correlations between nuclear tracer avidity and malignancy grade in cartilage tumours. METHODS: Between 1996 and 2000, 92 consecutive patients with cartilaginous tumours (50 benign, 42 non-metastatic malignant) underwent nuclear scanning. Thallium-201 (TL-201) and pentavalent dimercaptosuccinic acid (DMSAV) were used as nuclear isotopes. Scanning with these agents was performed on separate days 48 hours apart. Static and SPECT images were obtained at 30 m and 4 h after injection of nuclear tracer. Pathology review was undertaken blinded to the results of the nuclear scans and correlations between histologic results and trace uptake at 4 hours examined. RESULTS: 25 patients with negative DMSAV had benign tumours. 15/17 tumours with positive TL-201 had malignant tumours. 11/13 patients with both positive DMSAV and TL-201 scans had intermediate or high grade tumours and 4 of these developed metastases. We have developed an algorithm for the management of patients with tumours that aims to avoid over treatment of low grade tumours and under treatment of high grade tumours. CONCLUSION: Functional nuclear scanning with TL-201 and DMSAV complements other imaging modalities in the management of cartilaginous tumours. More... »

PAGES

10

References to SciGraph publications

  • 2001-05. Low-grade chondrosarcoma vs enchondroma: challenges in diagnosis and management in EUROPEAN RADIOLOGY
  • 2000-04. Osteochondroma: MR imaging of tumor-related complications in EUROPEAN RADIOLOGY
  • 1996-02. Magnetic resonance imaging of cartilaginous tumors: is it useful or necessary? in SKELETAL RADIOLOGY
  • 1991-03. Histological grading and morphometric analysis of cartilaginous tumours in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • 1994-11. The value of thallium and three-phase bone scans in the evaluation of bone and soft tissue sarcomas in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1998-11. Value of thallium-201 scintigraphy in bone and soft tissue tumors in JOURNAL OF ORTHOPAEDIC SCIENCE
  • 1993-06. Borderline chondrosarcoma of long and flat bones in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 1995-06. Quantitative evaluation of thallium-201 uptake in predicting chemotherapeutic response of osteosarcoma in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1993-05. Unusual behavior of clear cell chondrosarcoma in SKELETAL RADIOLOGY
  • 1991-04. Clear cell chondrosarcoma of bone in SKELETAL RADIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1477-7800-1-10

    DOI

    http://dx.doi.org/10.1186/1477-7800-1-10

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1018983806

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/15533251


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Peter MacCallum Cancer Centre", 
              "id": "https://www.grid.ac/institutes/grid.1055.1", 
              "name": [
                "Department of Orthopaedics, University of Melbourne, St. Vincent's Hospital, Melbourne, Australia", 
                "Division of Surgical Oncology, Peter MacCallum Cancer Institute, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Choong", 
            "givenName": "Peter FM", 
            "id": "sg:person.010622362137.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010622362137.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Orthopaedics, University of Melbourne, St. Vincent's Hospital, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kunisada", 
            "givenName": "Toshiyuki", 
            "id": "sg:person.01062265031.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062265031.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "St Vincent's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.413105.2", 
              "name": [
                "Department of Pathology, St. Vincent's Hospital, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Slavin", 
            "givenName": "John", 
            "id": "sg:person.010053224442.99", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010053224442.99"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "St Vincent's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.413105.2", 
              "name": [
                "Department of Medical Imaging, St. Vincent's Hospital, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schlicht", 
            "givenName": "Stephen", 
            "id": "sg:person.01160430133.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160430133.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Peter MacCallum Cancer Centre", 
              "id": "https://www.grid.ac/institutes/grid.1055.1", 
              "name": [
                "Department of Medical Imaging, Peter MacCallum Cancer Institute, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hicks", 
            "givenName": "Rodney", 
            "id": "sg:person.01121233254.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121233254.97"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1097/00003072-199504000-00015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001661995"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199504000-00015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001661995"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-200108000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003948590"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-200108000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003948590"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-200108000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003948590"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0142(19991101)86:9<1724::aid-cncr14>3.0.co;2-i", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003982893"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1098-2388(199701/02)13:1<64::aid-ssu10>3.0.co;2-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006470997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0142(19970701)80:1<50::aid-cncr7>3.0.co;2-j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007116764"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s003300000651", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007750240", 
              "https://doi.org/10.1007/s003300000651"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01600290", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009012164", 
              "https://doi.org/10.1007/bf01600290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01600290", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009012164", 
              "https://doi.org/10.1007/bf01600290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19901001)66:7<1641::aid-cncr2820660732>3.0.co;2-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010971482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01208847", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011870756", 
              "https://doi.org/10.1007/bf01208847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01208847", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011870756", 
              "https://doi.org/10.1007/bf01208847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00182353", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012971230", 
              "https://doi.org/10.1007/bf00182353"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0889-8529(05)70314-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014211989"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0889-8529(05)70314-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014211989"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00817281", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021806573", 
              "https://doi.org/10.1007/bf00817281"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00817281", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021806573", 
              "https://doi.org/10.1007/bf00817281"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199202000-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025066161"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199202000-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025066161"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(20010401)91:7<1201::aid-cncr1120>3.0.co;2-w", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025102370"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/17453679508995543", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025656299"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0046-8177(95)90166-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026261620"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0720-048x(98)00048-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026879095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/230949900000800215", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027338270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/230949900000800215", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027338270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199104000-00012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028627588"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199104000-00012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028627588"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s003300051014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034009912", 
              "https://doi.org/10.1007/s003300051014"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00197674", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034099876", 
              "https://doi.org/10.1007/bf00197674"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00197674", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034099876", 
              "https://doi.org/10.1007/bf00197674"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0748-7983(98)91459-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036231518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0720-048x(98)00046-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036443556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00241664", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036480049", 
              "https://doi.org/10.1007/bf00241664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00241664", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036480049", 
              "https://doi.org/10.1007/bf00241664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000478-200008000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036747725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00000478-200008000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036747725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/17453674.1997.11744699", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039565514"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0046-8177(95)90004-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045975825"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s007760050056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050483299", 
              "https://doi.org/10.1007/s007760050056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0142(19981115)83:10<2105::aid-cncr9>3.0.co;2-u", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051605751"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s002560050050", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052211064", 
              "https://doi.org/10.1007/s002560050050"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/radiographics.18.5.9747616", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053634764"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199709000-00016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060151741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199709000-00016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060151741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199709000-00016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060151741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-199304000-00008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068891393"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-199903000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068893306"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5435/00124635-200009000-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072858808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074735278", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/107327480100800304", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074826091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/107327480100800304", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074826091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/radiographics.12.4.1636034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077163212"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/028418519103200405", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077194952"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/028418519103200405", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077194952"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077200066", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077878350", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079413002", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079504560", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080637667", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/128.3.701", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1081935814"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0889-8588(18)30084-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082449372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/radiology.186.3.8430192", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082803664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082928569", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2004-12", 
        "datePublishedReg": "2004-12-01", 
        "description": "INTRODUCTION: Heterogeneity of cartilage tumours may confound accurate diagnosis and grading resulting in under and over treatment. Improved preoperative assessment of malignancy and grade would be invaluable for developing a rational plan for treatment. We examined correlations between nuclear tracer avidity and malignancy grade in cartilage tumours. METHODS: Between 1996 and 2000, 92 consecutive patients with cartilaginous tumours (50 benign, 42 non-metastatic malignant) underwent nuclear scanning. Thallium-201 (TL-201) and pentavalent dimercaptosuccinic acid (DMSAV) were used as nuclear isotopes. Scanning with these agents was performed on separate days 48 hours apart. Static and SPECT images were obtained at 30 m and 4 h after injection of nuclear tracer. Pathology review was undertaken blinded to the results of the nuclear scans and correlations between histologic results and trace uptake at 4 hours examined. RESULTS: 25 patients with negative DMSAV had benign tumours. 15/17 tumours with positive TL-201 had malignant tumours. 11/13 patients with both positive DMSAV and TL-201 scans had intermediate or high grade tumours and 4 of these developed metastases. We have developed an algorithm for the management of patients with tumours that aims to avoid over treatment of low grade tumours and under treatment of high grade tumours. CONCLUSION: Functional nuclear scanning with TL-201 and DMSAV complements other imaging modalities in the management of cartilaginous tumours.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/1477-7800-1-10", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1033908", 
            "issn": [
              "1477-7800"
            ], 
            "name": "International Seminars in Surgical Oncology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "1"
          }
        ], 
        "name": "The role of thallium-201 and pentavalent dimercaptosuccinic acid for staging cartilaginous tumours", 
        "pagination": "10", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "5a739f53f25c86d6dbc46cf0f9debcacc398eaa68eeff109997b1f2fa2580ce3"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "15533251"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101219693"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/1477-7800-1-10"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1018983806"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/1477-7800-1-10", 
          "https://app.dimensions.ai/details/publication/pub.1018983806"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T18:25", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000536.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1186%2F1477-7800-1-10"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1477-7800-1-10'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1477-7800-1-10'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1477-7800-1-10'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1477-7800-1-10'


     

    This table displays all metadata directly associated to this object as RDF triples.

    251 TRIPLES      21 PREDICATES      77 URIs      21 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/1477-7800-1-10 schema:about anzsrc-for:11
    2 anzsrc-for:1103
    3 schema:author N240e7bc0a8b54b43878ae0fef1e5a818
    4 schema:citation sg:pub.10.1007/bf00182353
    5 sg:pub.10.1007/bf00197674
    6 sg:pub.10.1007/bf00241664
    7 sg:pub.10.1007/bf00817281
    8 sg:pub.10.1007/bf01208847
    9 sg:pub.10.1007/bf01600290
    10 sg:pub.10.1007/s002560050050
    11 sg:pub.10.1007/s003300000651
    12 sg:pub.10.1007/s003300051014
    13 sg:pub.10.1007/s007760050056
    14 https://app.dimensions.ai/details/publication/pub.1074735278
    15 https://app.dimensions.ai/details/publication/pub.1077200066
    16 https://app.dimensions.ai/details/publication/pub.1077878350
    17 https://app.dimensions.ai/details/publication/pub.1079413002
    18 https://app.dimensions.ai/details/publication/pub.1079504560
    19 https://app.dimensions.ai/details/publication/pub.1080637667
    20 https://app.dimensions.ai/details/publication/pub.1082928569
    21 https://doi.org/10.1002/(sici)1097-0142(19970701)80:1<50::aid-cncr7>3.0.co;2-j
    22 https://doi.org/10.1002/(sici)1097-0142(19981115)83:10<2105::aid-cncr9>3.0.co;2-u
    23 https://doi.org/10.1002/(sici)1097-0142(19991101)86:9<1724::aid-cncr14>3.0.co;2-i
    24 https://doi.org/10.1002/(sici)1098-2388(199701/02)13:1<64::aid-ssu10>3.0.co;2-9
    25 https://doi.org/10.1002/1097-0142(19901001)66:7<1641::aid-cncr2820660732>3.0.co;2-y
    26 https://doi.org/10.1002/1097-0142(20010401)91:7<1201::aid-cncr1120>3.0.co;2-w
    27 https://doi.org/10.1016/0046-8177(95)90004-7
    28 https://doi.org/10.1016/0046-8177(95)90166-3
    29 https://doi.org/10.1016/s0720-048x(98)00046-1
    30 https://doi.org/10.1016/s0720-048x(98)00048-5
    31 https://doi.org/10.1016/s0748-7983(98)91459-7
    32 https://doi.org/10.1016/s0889-8529(05)70314-5
    33 https://doi.org/10.1016/s0889-8588(18)30084-4
    34 https://doi.org/10.1080/17453674.1997.11744699
    35 https://doi.org/10.1097/00000478-200008000-00005
    36 https://doi.org/10.1097/00003072-199104000-00012
    37 https://doi.org/10.1097/00003072-199202000-00011
    38 https://doi.org/10.1097/00003072-199504000-00015
    39 https://doi.org/10.1097/00003072-199709000-00016
    40 https://doi.org/10.1097/00003072-200108000-00004
    41 https://doi.org/10.1148/128.3.701
    42 https://doi.org/10.1148/radiographics.12.4.1636034
    43 https://doi.org/10.1148/radiographics.18.5.9747616
    44 https://doi.org/10.1148/radiology.186.3.8430192
    45 https://doi.org/10.1177/028418519103200405
    46 https://doi.org/10.1177/107327480100800304
    47 https://doi.org/10.1177/230949900000800215
    48 https://doi.org/10.2106/00004623-199304000-00008
    49 https://doi.org/10.2106/00004623-199903000-00004
    50 https://doi.org/10.3109/17453679508995543
    51 https://doi.org/10.5435/00124635-200009000-00003
    52 schema:datePublished 2004-12
    53 schema:datePublishedReg 2004-12-01
    54 schema:description INTRODUCTION: Heterogeneity of cartilage tumours may confound accurate diagnosis and grading resulting in under and over treatment. Improved preoperative assessment of malignancy and grade would be invaluable for developing a rational plan for treatment. We examined correlations between nuclear tracer avidity and malignancy grade in cartilage tumours. METHODS: Between 1996 and 2000, 92 consecutive patients with cartilaginous tumours (50 benign, 42 non-metastatic malignant) underwent nuclear scanning. Thallium-201 (TL-201) and pentavalent dimercaptosuccinic acid (DMSAV) were used as nuclear isotopes. Scanning with these agents was performed on separate days 48 hours apart. Static and SPECT images were obtained at 30 m and 4 h after injection of nuclear tracer. Pathology review was undertaken blinded to the results of the nuclear scans and correlations between histologic results and trace uptake at 4 hours examined. RESULTS: 25 patients with negative DMSAV had benign tumours. 15/17 tumours with positive TL-201 had malignant tumours. 11/13 patients with both positive DMSAV and TL-201 scans had intermediate or high grade tumours and 4 of these developed metastases. We have developed an algorithm for the management of patients with tumours that aims to avoid over treatment of low grade tumours and under treatment of high grade tumours. CONCLUSION: Functional nuclear scanning with TL-201 and DMSAV complements other imaging modalities in the management of cartilaginous tumours.
    55 schema:genre research_article
    56 schema:inLanguage en
    57 schema:isAccessibleForFree true
    58 schema:isPartOf Na9255145eb8d412789346947873c650b
    59 Nf57e1151d9604d7086da1eabbaa06dd0
    60 sg:journal.1033908
    61 schema:name The role of thallium-201 and pentavalent dimercaptosuccinic acid for staging cartilaginous tumours
    62 schema:pagination 10
    63 schema:productId N716a04ef31ca4bfe8c7c2ec105184f74
    64 Nc7d61efbaad84e3aa0291d139c045fb5
    65 Nc9f79334dbe242328bb14189b64059b9
    66 Nca978dc5977644129895dabc489e2093
    67 Nfe1ef570aa1f4132ba7b94dda719bc60
    68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018983806
    69 https://doi.org/10.1186/1477-7800-1-10
    70 schema:sdDatePublished 2019-04-10T18:25
    71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    72 schema:sdPublisher N84cd3b831acd45c987b65310629598ca
    73 schema:url http://link.springer.com/10.1186%2F1477-7800-1-10
    74 sgo:license sg:explorer/license/
    75 sgo:sdDataset articles
    76 rdf:type schema:ScholarlyArticle
    77 N0cc626a7c10949df882938a7c15210ce rdf:first sg:person.01121233254.97
    78 rdf:rest rdf:nil
    79 N240e7bc0a8b54b43878ae0fef1e5a818 rdf:first sg:person.010622362137.43
    80 rdf:rest N4e06be8313ed41ac9eb7766252e7b41b
    81 N3ba87e2f463d4133b0256f79f59afa47 rdf:first sg:person.010053224442.99
    82 rdf:rest N4ab973c4cdbb46c3ae33d3adf5013b63
    83 N4ab973c4cdbb46c3ae33d3adf5013b63 rdf:first sg:person.01160430133.30
    84 rdf:rest N0cc626a7c10949df882938a7c15210ce
    85 N4e06be8313ed41ac9eb7766252e7b41b rdf:first sg:person.01062265031.31
    86 rdf:rest N3ba87e2f463d4133b0256f79f59afa47
    87 N716a04ef31ca4bfe8c7c2ec105184f74 schema:name pubmed_id
    88 schema:value 15533251
    89 rdf:type schema:PropertyValue
    90 N784d13822d3444c0a015c2a44dff5a24 schema:name Department of Orthopaedics, University of Melbourne, St. Vincent's Hospital, Melbourne, Australia
    91 rdf:type schema:Organization
    92 N84cd3b831acd45c987b65310629598ca schema:name Springer Nature - SN SciGraph project
    93 rdf:type schema:Organization
    94 Na9255145eb8d412789346947873c650b schema:volumeNumber 1
    95 rdf:type schema:PublicationVolume
    96 Nc7d61efbaad84e3aa0291d139c045fb5 schema:name nlm_unique_id
    97 schema:value 101219693
    98 rdf:type schema:PropertyValue
    99 Nc9f79334dbe242328bb14189b64059b9 schema:name doi
    100 schema:value 10.1186/1477-7800-1-10
    101 rdf:type schema:PropertyValue
    102 Nca978dc5977644129895dabc489e2093 schema:name dimensions_id
    103 schema:value pub.1018983806
    104 rdf:type schema:PropertyValue
    105 Nf57e1151d9604d7086da1eabbaa06dd0 schema:issueNumber 1
    106 rdf:type schema:PublicationIssue
    107 Nfe1ef570aa1f4132ba7b94dda719bc60 schema:name readcube_id
    108 schema:value 5a739f53f25c86d6dbc46cf0f9debcacc398eaa68eeff109997b1f2fa2580ce3
    109 rdf:type schema:PropertyValue
    110 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    111 schema:name Medical and Health Sciences
    112 rdf:type schema:DefinedTerm
    113 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    114 schema:name Clinical Sciences
    115 rdf:type schema:DefinedTerm
    116 sg:journal.1033908 schema:issn 1477-7800
    117 schema:name International Seminars in Surgical Oncology
    118 rdf:type schema:Periodical
    119 sg:person.010053224442.99 schema:affiliation https://www.grid.ac/institutes/grid.413105.2
    120 schema:familyName Slavin
    121 schema:givenName John
    122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010053224442.99
    123 rdf:type schema:Person
    124 sg:person.010622362137.43 schema:affiliation https://www.grid.ac/institutes/grid.1055.1
    125 schema:familyName Choong
    126 schema:givenName Peter FM
    127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010622362137.43
    128 rdf:type schema:Person
    129 sg:person.01062265031.31 schema:affiliation N784d13822d3444c0a015c2a44dff5a24
    130 schema:familyName Kunisada
    131 schema:givenName Toshiyuki
    132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062265031.31
    133 rdf:type schema:Person
    134 sg:person.01121233254.97 schema:affiliation https://www.grid.ac/institutes/grid.1055.1
    135 schema:familyName Hicks
    136 schema:givenName Rodney
    137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121233254.97
    138 rdf:type schema:Person
    139 sg:person.01160430133.30 schema:affiliation https://www.grid.ac/institutes/grid.413105.2
    140 schema:familyName Schlicht
    141 schema:givenName Stephen
    142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160430133.30
    143 rdf:type schema:Person
    144 sg:pub.10.1007/bf00182353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012971230
    145 https://doi.org/10.1007/bf00182353
    146 rdf:type schema:CreativeWork
    147 sg:pub.10.1007/bf00197674 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034099876
    148 https://doi.org/10.1007/bf00197674
    149 rdf:type schema:CreativeWork
    150 sg:pub.10.1007/bf00241664 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036480049
    151 https://doi.org/10.1007/bf00241664
    152 rdf:type schema:CreativeWork
    153 sg:pub.10.1007/bf00817281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021806573
    154 https://doi.org/10.1007/bf00817281
    155 rdf:type schema:CreativeWork
    156 sg:pub.10.1007/bf01208847 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011870756
    157 https://doi.org/10.1007/bf01208847
    158 rdf:type schema:CreativeWork
    159 sg:pub.10.1007/bf01600290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009012164
    160 https://doi.org/10.1007/bf01600290
    161 rdf:type schema:CreativeWork
    162 sg:pub.10.1007/s002560050050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052211064
    163 https://doi.org/10.1007/s002560050050
    164 rdf:type schema:CreativeWork
    165 sg:pub.10.1007/s003300000651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007750240
    166 https://doi.org/10.1007/s003300000651
    167 rdf:type schema:CreativeWork
    168 sg:pub.10.1007/s003300051014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034009912
    169 https://doi.org/10.1007/s003300051014
    170 rdf:type schema:CreativeWork
    171 sg:pub.10.1007/s007760050056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050483299
    172 https://doi.org/10.1007/s007760050056
    173 rdf:type schema:CreativeWork
    174 https://app.dimensions.ai/details/publication/pub.1074735278 schema:CreativeWork
    175 https://app.dimensions.ai/details/publication/pub.1077200066 schema:CreativeWork
    176 https://app.dimensions.ai/details/publication/pub.1077878350 schema:CreativeWork
    177 https://app.dimensions.ai/details/publication/pub.1079413002 schema:CreativeWork
    178 https://app.dimensions.ai/details/publication/pub.1079504560 schema:CreativeWork
    179 https://app.dimensions.ai/details/publication/pub.1080637667 schema:CreativeWork
    180 https://app.dimensions.ai/details/publication/pub.1082928569 schema:CreativeWork
    181 https://doi.org/10.1002/(sici)1097-0142(19970701)80:1<50::aid-cncr7>3.0.co;2-j schema:sameAs https://app.dimensions.ai/details/publication/pub.1007116764
    182 rdf:type schema:CreativeWork
    183 https://doi.org/10.1002/(sici)1097-0142(19981115)83:10<2105::aid-cncr9>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1051605751
    184 rdf:type schema:CreativeWork
    185 https://doi.org/10.1002/(sici)1097-0142(19991101)86:9<1724::aid-cncr14>3.0.co;2-i schema:sameAs https://app.dimensions.ai/details/publication/pub.1003982893
    186 rdf:type schema:CreativeWork
    187 https://doi.org/10.1002/(sici)1098-2388(199701/02)13:1<64::aid-ssu10>3.0.co;2-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006470997
    188 rdf:type schema:CreativeWork
    189 https://doi.org/10.1002/1097-0142(19901001)66:7<1641::aid-cncr2820660732>3.0.co;2-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1010971482
    190 rdf:type schema:CreativeWork
    191 https://doi.org/10.1002/1097-0142(20010401)91:7<1201::aid-cncr1120>3.0.co;2-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1025102370
    192 rdf:type schema:CreativeWork
    193 https://doi.org/10.1016/0046-8177(95)90004-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045975825
    194 rdf:type schema:CreativeWork
    195 https://doi.org/10.1016/0046-8177(95)90166-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026261620
    196 rdf:type schema:CreativeWork
    197 https://doi.org/10.1016/s0720-048x(98)00046-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036443556
    198 rdf:type schema:CreativeWork
    199 https://doi.org/10.1016/s0720-048x(98)00048-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026879095
    200 rdf:type schema:CreativeWork
    201 https://doi.org/10.1016/s0748-7983(98)91459-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036231518
    202 rdf:type schema:CreativeWork
    203 https://doi.org/10.1016/s0889-8529(05)70314-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014211989
    204 rdf:type schema:CreativeWork
    205 https://doi.org/10.1016/s0889-8588(18)30084-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082449372
    206 rdf:type schema:CreativeWork
    207 https://doi.org/10.1080/17453674.1997.11744699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039565514
    208 rdf:type schema:CreativeWork
    209 https://doi.org/10.1097/00000478-200008000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036747725
    210 rdf:type schema:CreativeWork
    211 https://doi.org/10.1097/00003072-199104000-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028627588
    212 rdf:type schema:CreativeWork
    213 https://doi.org/10.1097/00003072-199202000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025066161
    214 rdf:type schema:CreativeWork
    215 https://doi.org/10.1097/00003072-199504000-00015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001661995
    216 rdf:type schema:CreativeWork
    217 https://doi.org/10.1097/00003072-199709000-00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060151741
    218 rdf:type schema:CreativeWork
    219 https://doi.org/10.1097/00003072-200108000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003948590
    220 rdf:type schema:CreativeWork
    221 https://doi.org/10.1148/128.3.701 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081935814
    222 rdf:type schema:CreativeWork
    223 https://doi.org/10.1148/radiographics.12.4.1636034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077163212
    224 rdf:type schema:CreativeWork
    225 https://doi.org/10.1148/radiographics.18.5.9747616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053634764
    226 rdf:type schema:CreativeWork
    227 https://doi.org/10.1148/radiology.186.3.8430192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082803664
    228 rdf:type schema:CreativeWork
    229 https://doi.org/10.1177/028418519103200405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077194952
    230 rdf:type schema:CreativeWork
    231 https://doi.org/10.1177/107327480100800304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074826091
    232 rdf:type schema:CreativeWork
    233 https://doi.org/10.1177/230949900000800215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027338270
    234 rdf:type schema:CreativeWork
    235 https://doi.org/10.2106/00004623-199304000-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068891393
    236 rdf:type schema:CreativeWork
    237 https://doi.org/10.2106/00004623-199903000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068893306
    238 rdf:type schema:CreativeWork
    239 https://doi.org/10.3109/17453679508995543 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025656299
    240 rdf:type schema:CreativeWork
    241 https://doi.org/10.5435/00124635-200009000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072858808
    242 rdf:type schema:CreativeWork
    243 https://www.grid.ac/institutes/grid.1055.1 schema:alternateName Peter MacCallum Cancer Centre
    244 schema:name Department of Medical Imaging, Peter MacCallum Cancer Institute, Melbourne, Australia
    245 Department of Orthopaedics, University of Melbourne, St. Vincent's Hospital, Melbourne, Australia
    246 Division of Surgical Oncology, Peter MacCallum Cancer Institute, Melbourne, Australia
    247 rdf:type schema:Organization
    248 https://www.grid.ac/institutes/grid.413105.2 schema:alternateName St Vincent's Hospital
    249 schema:name Department of Medical Imaging, St. Vincent's Hospital, Melbourne, Australia
    250 Department of Pathology, St. Vincent's Hospital, Melbourne, Australia
    251 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...