Host factors do not influence the colonization or infection by fluconazole resistant Candida species in hospitalized patients View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-12

AUTHORS

Yun-Liang Yang, Ming-Fang Cheng, Ya-Wen Chang, Tzuu-Guang Young, Hsin Chi, Sai Cheong Lee, Bruno Man-Hon Cheung, Fan-Chen Tseng, Tun-Chieh Chen, Yu-Huai Ho, Zhi-Yuan Shi, Chung-Huang Hubert Chan, Ju-Yu Lin, Hsiu-Jung Lo

ABSTRACT

Nosocomial yeast infections have significantly increased during the past two decades in industrialized countries, including Taiwan. This has been associated with the emergence of resistance to fluconazole and other antifungal drugs. The medical records of 88 patients, colonized or infected with Candida species, from nine of the 22 hospitals that provided clinical isolates to the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) program in 1999 were reviewed. A total of 35 patients contributed fluconazole resistant strains [minimum inhibitory concentrations (MICs) > or = 64 mg/l], while the remaining 53 patients contributed susceptible ones (MICs < or = 8 mg/l). Fluconazole resistance was more frequent among isolates of Candida tropicalis (46.5%) than either C. albicans (36.8%) or C. glabrata (30.8%). There was no significant difference in demographic characteristics or underlying diseases among patients contributing strains different in drug susceptibility. More... »

PAGES

12

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1477-5751-7-12

DOI

http://dx.doi.org/10.1186/1477-5751-7-12

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021638072

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19087319


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