Combined single-molecule force and fluorescence measurements for biology View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2003-03

AUTHORS

Mark I Wallace, Justin E Molloy, David R Trentham

ABSTRACT

Recent advances in single-molecule techniques allow the application of force to an individual biomolecule whilst simultaneously monitoring its response using fluorescent probes. The effects of applied mechanical load on single-enzyme turnovers, biomolecular interactions and conformational changes can now be studied with nanometer precision and millisecond time resolution.

PAGES

4

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1475-4924-2-4

DOI

http://dx.doi.org/10.1186/1475-4924-2-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047760418

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12733995


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