Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-09-30

AUTHORS

Richard J Maude, Chea Nguon, Po Ly, Tol Bunkea, Pengby Ngor, Sara E Canavati de la Torre, Nicholas J White, Arjen M Dondorp, Nicholas PJ Day, Lisa J White, Char Meng Chuor

ABSTRACT

BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria has recently been identified on the Thailand-Cambodia border and more recently in parts of Thailand, Myanmar and Vietnam. There is concern that if this resistance were to spread, it would severely hamper malaria control and elimination efforts worldwide. Efforts are currently underway to intensify malaria control activities and ultimately eliminate malaria from Cambodia. To support these efforts, it is crucial to have a detailed picture of disease burden and its major determinants over time. METHODS: An analysis of spatial and temporal data on clinical malaria in Cambodia collected by the National Centre for Parasitology, Entomology and Malaria Control (CNM) and the Department of Planning and Health Information, Ministry of Health Cambodia from 2004 to 2013 is presented. RESULTS: There has been a marked decrease of 81% in annual cases due to P. falciparum since 2009 coinciding with a rapid scale-up in village malaria workers (VMWs) and insecticide-treated bed nets (ITNs). Concurrently, the number of cases with Plasmodium vivax has greatly increased. It is estimated that there were around 112,000 total cases in 2012, 2.8 times greater than the WHO estimate for that year, and 68,000 in 2013 (an annual parasite incidence (API) of 4.6/1000). With the scale-up of VMWs, numbers of patients presenting to government facilities did not fall and it appears likely that those who saw VMWs had previously accessed healthcare in the private sector. Malaria mortality has decreased, particularly in areas with VMWs. There has been a marked decrease in cases in parts of western Cambodia, especially in Pailin and Battambang Provinces. In the northeast, the fall in malaria burden has been more modest, this area having the highest API in 2013. CONCLUSION: The clinical burden of falciparum malaria in most areas of Cambodia has greatly decreased from 2009 to 2013, associated with roll-out of ITNs and VMWs. Numbers of cases with P. vivax have increased. Possible reasons for these trends are discussed and areas requiring further study are highlighted. Although malaria surveillance data are prone to collection bias and tend to underestimate disease burden, the finding of similar trends in two independent datasets in this study greatly increased the robustness of the findings. More... »

PAGES

385

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1475-2875-13-385

DOI

http://dx.doi.org/10.1186/1475-2875-13-385

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029511199

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25266007


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cambodia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Communicable Disease Control", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria, Falciparum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria, Vivax", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prevalence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spatio-Temporal Analysis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maude", 
        "givenName": "Richard J", 
        "id": "sg:person.013727356027.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013727356027.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
          "id": "http://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nguon", 
        "givenName": "Chea", 
        "id": "sg:person.0707431241.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707431241.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
          "id": "http://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ly", 
        "givenName": "Po", 
        "id": "sg:person.01073062625.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073062625.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
          "id": "http://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bunkea", 
        "givenName": "Tol", 
        "id": "sg:person.01202660364.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202660364.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
          "id": "http://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ngor", 
        "givenName": "Pengby", 
        "id": "sg:person.01336750330.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336750330.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
          "id": "http://www.grid.ac/institutes/grid.10223.32", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
            "Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de la Torre", 
        "givenName": "Sara E Canavati", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Nicholas J", 
        "id": "sg:person.01332073522.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332073522.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dondorp", 
        "givenName": "Arjen M", 
        "id": "sg:person.01162317707.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162317707.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Day", 
        "givenName": "Nicholas PJ", 
        "id": "sg:person.013570515662.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013570515662.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Lisa J", 
        "id": "sg:person.01302212135.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302212135.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
          "id": "http://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chuor", 
        "givenName": "Char Meng", 
        "id": "sg:person.0736216222.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1475-2875-8-31", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018894370", 
          "https://doi.org/10.1186/1475-2875-8-31"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-8-142", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052536364", 
          "https://doi.org/10.1186/1475-2875-8-142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-7-96", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035357393", 
          "https://doi.org/10.1186/1475-2875-7-96"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-6-37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051443131", 
          "https://doi.org/10.1186/1475-2875-6-37"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028137830", 
          "https://doi.org/10.1186/1475-2875-11-355"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-09-30", 
    "datePublishedReg": "2014-09-30", 
    "description": "BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria has recently been identified on the Thailand-Cambodia border and more recently in parts of Thailand, Myanmar and Vietnam. There is concern that if this resistance were to spread, it would severely hamper malaria control and elimination efforts worldwide. Efforts are currently underway to intensify malaria control activities and ultimately eliminate malaria from Cambodia. To support these efforts, it is crucial to have a detailed picture of disease burden and its major determinants over time.\nMETHODS: An analysis of spatial and temporal data on clinical malaria in Cambodia collected by the National Centre for Parasitology, Entomology and Malaria Control (CNM) and the Department of Planning and Health Information, Ministry of Health Cambodia from 2004 to 2013 is presented.\nRESULTS: There has been a marked decrease of 81% in annual cases due to P. falciparum since 2009 coinciding with a rapid scale-up in village malaria workers (VMWs) and insecticide-treated bed nets (ITNs). Concurrently, the number of cases with Plasmodium vivax has greatly increased. It is estimated that there were around 112,000 total cases in 2012, 2.8 times greater than the WHO estimate for that year, and 68,000 in 2013 (an annual parasite incidence (API) of 4.6/1000). With the scale-up of VMWs, numbers of patients presenting to government facilities did not fall and it appears likely that those who saw VMWs had previously accessed healthcare in the private sector. Malaria mortality has decreased, particularly in areas with VMWs. There has been a marked decrease in cases in parts of western Cambodia, especially in Pailin and Battambang Provinces. In the northeast, the fall in malaria burden has been more modest, this area having the highest API in 2013.\nCONCLUSION: The clinical burden of falciparum malaria in most areas of Cambodia has greatly decreased from 2009 to 2013, associated with roll-out of ITNs and VMWs. Numbers of cases with P. vivax have increased. Possible reasons for these trends are discussed and areas requiring further study are highlighted. Although malaria surveillance data are prone to collection bias and tend to underestimate disease burden, the finding of similar trends in two independent datasets in this study greatly increased the robustness of the findings.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/1475-2875-13-385", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3642719", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030597", 
        "issn": [
          "1475-2875"
        ], 
        "name": "Malaria Journal", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "keywords": [
      "village malaria workers", 
      "clinical malaria", 
      "falciparum malaria", 
      "disease burden", 
      "artemisinin-resistant Plasmodium falciparum malaria", 
      "number of cases", 
      "malaria control", 
      "Plasmodium falciparum malaria", 
      "number of patients", 
      "malaria control activities", 
      "malaria surveillance data", 
      "Thailand-Cambodia border", 
      "malaria workers", 
      "clinical burden", 
      "malaria mortality", 
      "malaria burden", 
      "Plasmodium vivax", 
      "total cases", 
      "elimination efforts", 
      "bed nets", 
      "western Cambodia", 
      "annual cases", 
      "malaria", 
      "surveillance data", 
      "temporal epidemiology", 
      "health information", 
      "Further studies", 
      "burden", 
      "vivax", 
      "major determinant", 
      "government facilities", 
      "control activities", 
      "parts of Thailand", 
      "patients", 
      "cases", 
      "mortality", 
      "findings", 
      "epidemiology", 
      "Pailin", 
      "falciparum", 
      "ITNs", 
      "independent datasets", 
      "decrease", 
      "Battambang Province", 
      "control", 
      "study", 
      "similar trend", 
      "National Center", 
      "Department", 
      "high API", 
      "Cambodia", 
      "healthcare", 
      "years", 
      "fall", 
      "possible reasons", 
      "number", 
      "determinants", 
      "parasitology", 
      "data", 
      "most areas", 
      "area", 
      "activity", 
      "center", 
      "workers", 
      "time", 
      "resistance", 
      "efforts", 
      "trends", 
      "Thailand", 
      "collection bias", 
      "part", 
      "concern", 
      "reasons", 
      "border", 
      "facilities", 
      "bias", 
      "Ministry", 
      "analysis", 
      "picture", 
      "information", 
      "Province", 
      "planning", 
      "Vietnam", 
      "Myanmar", 
      "private sector", 
      "northeast", 
      "Department of Planning", 
      "detailed picture", 
      "nets", 
      "dataset", 
      "temporal data", 
      "entomology", 
      "sector", 
      "API", 
      "robustness", 
      "Health Cambodia", 
      "Cambodia 2004"
    ], 
    "name": "Spatial and temporal epidemiology of clinical malaria in Cambodia 2004\u20132013", 
    "pagination": "385", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1029511199"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1475-2875-13-385"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25266007"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1475-2875-13-385", 
      "https://app.dimensions.ai/details/publication/pub.1029511199"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:33", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_633.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/1475-2875-13-385"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'


 

This table displays all metadata directly associated to this object as RDF triples.

291 TRIPLES      22 PREDICATES      136 URIs      122 LITERALS      14 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1475-2875-13-385 schema:about N19f658d09d2b44ea9b8c373608358b64
2 N713b94c62d6f4ce0aec311c619ce793d
3 N7d0187ec63814d2c96cb66247f69960e
4 N8ca653bb672248ceb1297284a929bc8d
5 N97253b691d494eb5a385bc7168605d4d
6 Na8a29a0a5a334a4c8c90e288d6521739
7 Nde24ce925fa040e49f961fa4de75bda8
8 anzsrc-for:11
9 anzsrc-for:1108
10 anzsrc-for:1117
11 schema:author N2c2f6a77e5214b7fb0f7dfdfb2faea6c
12 schema:citation sg:pub.10.1186/1475-2875-11-355
13 sg:pub.10.1186/1475-2875-6-37
14 sg:pub.10.1186/1475-2875-7-96
15 sg:pub.10.1186/1475-2875-8-142
16 sg:pub.10.1186/1475-2875-8-31
17 schema:datePublished 2014-09-30
18 schema:datePublishedReg 2014-09-30
19 schema:description BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria has recently been identified on the Thailand-Cambodia border and more recently in parts of Thailand, Myanmar and Vietnam. There is concern that if this resistance were to spread, it would severely hamper malaria control and elimination efforts worldwide. Efforts are currently underway to intensify malaria control activities and ultimately eliminate malaria from Cambodia. To support these efforts, it is crucial to have a detailed picture of disease burden and its major determinants over time. METHODS: An analysis of spatial and temporal data on clinical malaria in Cambodia collected by the National Centre for Parasitology, Entomology and Malaria Control (CNM) and the Department of Planning and Health Information, Ministry of Health Cambodia from 2004 to 2013 is presented. RESULTS: There has been a marked decrease of 81% in annual cases due to P. falciparum since 2009 coinciding with a rapid scale-up in village malaria workers (VMWs) and insecticide-treated bed nets (ITNs). Concurrently, the number of cases with Plasmodium vivax has greatly increased. It is estimated that there were around 112,000 total cases in 2012, 2.8 times greater than the WHO estimate for that year, and 68,000 in 2013 (an annual parasite incidence (API) of 4.6/1000). With the scale-up of VMWs, numbers of patients presenting to government facilities did not fall and it appears likely that those who saw VMWs had previously accessed healthcare in the private sector. Malaria mortality has decreased, particularly in areas with VMWs. There has been a marked decrease in cases in parts of western Cambodia, especially in Pailin and Battambang Provinces. In the northeast, the fall in malaria burden has been more modest, this area having the highest API in 2013. CONCLUSION: The clinical burden of falciparum malaria in most areas of Cambodia has greatly decreased from 2009 to 2013, associated with roll-out of ITNs and VMWs. Numbers of cases with P. vivax have increased. Possible reasons for these trends are discussed and areas requiring further study are highlighted. Although malaria surveillance data are prone to collection bias and tend to underestimate disease burden, the finding of similar trends in two independent datasets in this study greatly increased the robustness of the findings.
20 schema:genre article
21 schema:inLanguage en
22 schema:isAccessibleForFree true
23 schema:isPartOf N235c27c7a1b24b7aa7aa8e528e665fa6
24 N69b8e3c4f3ca4e24be4a32eb6f62ea79
25 sg:journal.1030597
26 schema:keywords API
27 Battambang Province
28 Cambodia
29 Cambodia 2004
30 Department
31 Department of Planning
32 Further studies
33 Health Cambodia
34 ITNs
35 Ministry
36 Myanmar
37 National Center
38 Pailin
39 Plasmodium falciparum malaria
40 Plasmodium vivax
41 Province
42 Thailand
43 Thailand-Cambodia border
44 Vietnam
45 activity
46 analysis
47 annual cases
48 area
49 artemisinin-resistant Plasmodium falciparum malaria
50 bed nets
51 bias
52 border
53 burden
54 cases
55 center
56 clinical burden
57 clinical malaria
58 collection bias
59 concern
60 control
61 control activities
62 data
63 dataset
64 decrease
65 detailed picture
66 determinants
67 disease burden
68 efforts
69 elimination efforts
70 entomology
71 epidemiology
72 facilities
73 falciparum
74 falciparum malaria
75 fall
76 findings
77 government facilities
78 health information
79 healthcare
80 high API
81 independent datasets
82 information
83 major determinant
84 malaria
85 malaria burden
86 malaria control
87 malaria control activities
88 malaria mortality
89 malaria surveillance data
90 malaria workers
91 mortality
92 most areas
93 nets
94 northeast
95 number
96 number of cases
97 number of patients
98 parasitology
99 part
100 parts of Thailand
101 patients
102 picture
103 planning
104 possible reasons
105 private sector
106 reasons
107 resistance
108 robustness
109 sector
110 similar trend
111 study
112 surveillance data
113 temporal data
114 temporal epidemiology
115 time
116 total cases
117 trends
118 village malaria workers
119 vivax
120 western Cambodia
121 workers
122 years
123 schema:name Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013
124 schema:pagination 385
125 schema:productId N4047988c21e34752a4df28eb61cbf563
126 N83c1a0e8762347f6958130fe8494fcf0
127 N86434b6540284a3789188f05c60d5658
128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029511199
129 https://doi.org/10.1186/1475-2875-13-385
130 schema:sdDatePublished 2022-01-01T18:33
131 schema:sdLicense https://scigraph.springernature.com/explorer/license/
132 schema:sdPublisher N08d1815942bb489fa8a81017b2bb7e3c
133 schema:url https://doi.org/10.1186/1475-2875-13-385
134 sgo:license sg:explorer/license/
135 sgo:sdDataset articles
136 rdf:type schema:ScholarlyArticle
137 N06a4df4ee0d6487b8e232732df7aa350 schema:affiliation grid-institutes:grid.10223.32
138 schema:familyName de la Torre
139 schema:givenName Sara E Canavati
140 rdf:type schema:Person
141 N08d1815942bb489fa8a81017b2bb7e3c schema:name Springer Nature - SN SciGraph project
142 rdf:type schema:Organization
143 N19f658d09d2b44ea9b8c373608358b64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Prevalence
145 rdf:type schema:DefinedTerm
146 N1dea1bf4dcbd45af8f92d2950d49397e rdf:first sg:person.013570515662.78
147 rdf:rest Nb162d6bab7904207a6d1a66b8fb52af2
148 N235c27c7a1b24b7aa7aa8e528e665fa6 schema:volumeNumber 13
149 rdf:type schema:PublicationVolume
150 N280a3d54979d4687b22372630cd1d6de rdf:first sg:person.01202660364.57
151 rdf:rest Nd3280eae77a641ea89a3ea7d84b026aa
152 N2c2f6a77e5214b7fb0f7dfdfb2faea6c rdf:first sg:person.013727356027.81
153 rdf:rest N4f125eb9defb45e4b4243e60790b32e8
154 N4047988c21e34752a4df28eb61cbf563 schema:name doi
155 schema:value 10.1186/1475-2875-13-385
156 rdf:type schema:PropertyValue
157 N4f125eb9defb45e4b4243e60790b32e8 rdf:first sg:person.0707431241.45
158 rdf:rest N8cb43c0fadb442cd8bac047a94ef17cf
159 N69b8e3c4f3ca4e24be4a32eb6f62ea79 schema:issueNumber 1
160 rdf:type schema:PublicationIssue
161 N713b94c62d6f4ce0aec311c619ce793d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Communicable Disease Control
163 rdf:type schema:DefinedTerm
164 N7d0187ec63814d2c96cb66247f69960e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Humans
166 rdf:type schema:DefinedTerm
167 N83c1a0e8762347f6958130fe8494fcf0 schema:name pubmed_id
168 schema:value 25266007
169 rdf:type schema:PropertyValue
170 N86434b6540284a3789188f05c60d5658 schema:name dimensions_id
171 schema:value pub.1029511199
172 rdf:type schema:PropertyValue
173 N8ca653bb672248ceb1297284a929bc8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Malaria, Vivax
175 rdf:type schema:DefinedTerm
176 N8cb43c0fadb442cd8bac047a94ef17cf rdf:first sg:person.01073062625.06
177 rdf:rest N280a3d54979d4687b22372630cd1d6de
178 N97253b691d494eb5a385bc7168605d4d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Malaria, Falciparum
180 rdf:type schema:DefinedTerm
181 Na8a29a0a5a334a4c8c90e288d6521739 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Cambodia
183 rdf:type schema:DefinedTerm
184 Nb162d6bab7904207a6d1a66b8fb52af2 rdf:first sg:person.01302212135.78
185 rdf:rest Nebb2afe44dc347f990dd77f35dbb023c
186 Nb7f31d77e0dd4dd7a23ccc2b80bc60e6 rdf:first N06a4df4ee0d6487b8e232732df7aa350
187 rdf:rest Nc21c47f7cfea4d19bf5e8b69e0683301
188 Nc21c47f7cfea4d19bf5e8b69e0683301 rdf:first sg:person.01332073522.49
189 rdf:rest Nce1e9a3b5082476a81ebcfa068398dcc
190 Nce1e9a3b5082476a81ebcfa068398dcc rdf:first sg:person.01162317707.88
191 rdf:rest N1dea1bf4dcbd45af8f92d2950d49397e
192 Nd3280eae77a641ea89a3ea7d84b026aa rdf:first sg:person.01336750330.01
193 rdf:rest Nb7f31d77e0dd4dd7a23ccc2b80bc60e6
194 Nde24ce925fa040e49f961fa4de75bda8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Spatio-Temporal Analysis
196 rdf:type schema:DefinedTerm
197 Nebb2afe44dc347f990dd77f35dbb023c rdf:first sg:person.0736216222.41
198 rdf:rest rdf:nil
199 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
200 schema:name Medical and Health Sciences
201 rdf:type schema:DefinedTerm
202 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
203 schema:name Medical Microbiology
204 rdf:type schema:DefinedTerm
205 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
206 schema:name Public Health and Health Services
207 rdf:type schema:DefinedTerm
208 sg:grant.3642719 http://pending.schema.org/fundedItem sg:pub.10.1186/1475-2875-13-385
209 rdf:type schema:MonetaryGrant
210 sg:journal.1030597 schema:issn 1475-2875
211 schema:name Malaria Journal
212 schema:publisher Springer Nature
213 rdf:type schema:Periodical
214 sg:person.01073062625.06 schema:affiliation grid-institutes:grid.452707.3
215 schema:familyName Ly
216 schema:givenName Po
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073062625.06
218 rdf:type schema:Person
219 sg:person.01162317707.88 schema:affiliation grid-institutes:grid.4991.5
220 schema:familyName Dondorp
221 schema:givenName Arjen M
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162317707.88
223 rdf:type schema:Person
224 sg:person.01202660364.57 schema:affiliation grid-institutes:grid.452707.3
225 schema:familyName Bunkea
226 schema:givenName Tol
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202660364.57
228 rdf:type schema:Person
229 sg:person.01302212135.78 schema:affiliation grid-institutes:grid.4991.5
230 schema:familyName White
231 schema:givenName Lisa J
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302212135.78
233 rdf:type schema:Person
234 sg:person.01332073522.49 schema:affiliation grid-institutes:grid.4991.5
235 schema:familyName White
236 schema:givenName Nicholas J
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332073522.49
238 rdf:type schema:Person
239 sg:person.01336750330.01 schema:affiliation grid-institutes:grid.452707.3
240 schema:familyName Ngor
241 schema:givenName Pengby
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336750330.01
243 rdf:type schema:Person
244 sg:person.013570515662.78 schema:affiliation grid-institutes:grid.4991.5
245 schema:familyName Day
246 schema:givenName Nicholas PJ
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013570515662.78
248 rdf:type schema:Person
249 sg:person.013727356027.81 schema:affiliation grid-institutes:grid.4991.5
250 schema:familyName Maude
251 schema:givenName Richard J
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013727356027.81
253 rdf:type schema:Person
254 sg:person.0707431241.45 schema:affiliation grid-institutes:grid.452707.3
255 schema:familyName Nguon
256 schema:givenName Chea
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707431241.45
258 rdf:type schema:Person
259 sg:person.0736216222.41 schema:affiliation grid-institutes:grid.452707.3
260 schema:familyName Chuor
261 schema:givenName Char Meng
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41
263 rdf:type schema:Person
264 sg:pub.10.1186/1475-2875-11-355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028137830
265 https://doi.org/10.1186/1475-2875-11-355
266 rdf:type schema:CreativeWork
267 sg:pub.10.1186/1475-2875-6-37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051443131
268 https://doi.org/10.1186/1475-2875-6-37
269 rdf:type schema:CreativeWork
270 sg:pub.10.1186/1475-2875-7-96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035357393
271 https://doi.org/10.1186/1475-2875-7-96
272 rdf:type schema:CreativeWork
273 sg:pub.10.1186/1475-2875-8-142 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052536364
274 https://doi.org/10.1186/1475-2875-8-142
275 rdf:type schema:CreativeWork
276 sg:pub.10.1186/1475-2875-8-31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018894370
277 https://doi.org/10.1186/1475-2875-8-31
278 rdf:type schema:CreativeWork
279 grid-institutes:grid.10223.32 schema:alternateName Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
280 schema:name Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
281 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
282 National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
283 rdf:type schema:Organization
284 grid-institutes:grid.452707.3 schema:alternateName National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
285 schema:name Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
286 National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
287 rdf:type schema:Organization
288 grid-institutes:grid.4991.5 schema:alternateName Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK
289 schema:name Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK
290 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
291 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...