Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Richard J Maude, Chea Nguon, Po Ly, Tol Bunkea, Pengby Ngor, Sara E Canavati de la Torre, Nicholas J White, Arjen M Dondorp, Nicholas PJ Day, Lisa J White, Char Meng Chuor

ABSTRACT

BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria has recently been identified on the Thailand-Cambodia border and more recently in parts of Thailand, Myanmar and Vietnam. There is concern that if this resistance were to spread, it would severely hamper malaria control and elimination efforts worldwide. Efforts are currently underway to intensify malaria control activities and ultimately eliminate malaria from Cambodia. To support these efforts, it is crucial to have a detailed picture of disease burden and its major determinants over time. METHODS: An analysis of spatial and temporal data on clinical malaria in Cambodia collected by the National Centre for Parasitology, Entomology and Malaria Control (CNM) and the Department of Planning and Health Information, Ministry of Health Cambodia from 2004 to 2013 is presented. RESULTS: There has been a marked decrease of 81% in annual cases due to P. falciparum since 2009 coinciding with a rapid scale-up in village malaria workers (VMWs) and insecticide-treated bed nets (ITNs). Concurrently, the number of cases with Plasmodium vivax has greatly increased. It is estimated that there were around 112,000 total cases in 2012, 2.8 times greater than the WHO estimate for that year, and 68,000 in 2013 (an annual parasite incidence (API) of 4.6/1000). With the scale-up of VMWs, numbers of patients presenting to government facilities did not fall and it appears likely that those who saw VMWs had previously accessed healthcare in the private sector. Malaria mortality has decreased, particularly in areas with VMWs. There has been a marked decrease in cases in parts of western Cambodia, especially in Pailin and Battambang Provinces. In the northeast, the fall in malaria burden has been more modest, this area having the highest API in 2013. CONCLUSION: The clinical burden of falciparum malaria in most areas of Cambodia has greatly decreased from 2009 to 2013, associated with roll-out of ITNs and VMWs. Numbers of cases with P. vivax have increased. Possible reasons for these trends are discussed and areas requiring further study are highlighted. Although malaria surveillance data are prone to collection bias and tend to underestimate disease burden, the finding of similar trends in two independent datasets in this study greatly increased the robustness of the findings. More... »

PAGES

385

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1475-2875-13-385

DOI

http://dx.doi.org/10.1186/1475-2875-13-385

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029511199

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25266007


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cambodia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Communicable Disease Control", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria, Falciparum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria, Vivax", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prevalence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spatio-Temporal Analysis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maude", 
        "givenName": "Richard J", 
        "id": "sg:person.013727356027.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013727356027.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nguon", 
        "givenName": "Chea", 
        "id": "sg:person.0707431241.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707431241.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ly", 
        "givenName": "Po", 
        "id": "sg:person.01073062625.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073062625.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bunkea", 
        "givenName": "Tol", 
        "id": "sg:person.01202660364.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202660364.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ngor", 
        "givenName": "Pengby", 
        "id": "sg:person.01336750330.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336750330.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahidol University", 
          "id": "https://www.grid.ac/institutes/grid.10223.32", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia", 
            "Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Canavati de la Torre", 
        "givenName": "Sara E", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Nicholas J", 
        "id": "sg:person.01332073522.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332073522.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dondorp", 
        "givenName": "Arjen M", 
        "id": "sg:person.01162317707.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162317707.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Day", 
        "givenName": "Nicholas PJ", 
        "id": "sg:person.013570515662.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013570515662.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Lisa J", 
        "id": "sg:person.01302212135.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302212135.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chuor", 
        "givenName": "Char Meng", 
        "id": "sg:person.0736216222.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pone.0057689", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001233277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1890/08-1022.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010996559"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-8-31", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018894370", 
          "https://doi.org/10.1186/1475-2875-8-31"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmp1108322", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020900302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ddr.20344", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024068330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ddr.20344", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024068330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(10)61963-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026127494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.1001040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026505822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028137830", 
          "https://doi.org/10.1186/1475-2875-11-355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-7-96", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035357393", 
          "https://doi.org/10.1186/1475-2875-7-96"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2013/363417", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038609963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0037166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044060061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1473-3099(12)70181-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047536348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-6-37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051443131", 
          "https://doi.org/10.1186/1475-2875-6-37"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-8-142", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052536364", 
          "https://doi.org/10.1186/1475-2875-8-142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(12)60484-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053009002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077389654", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-12", 
    "datePublishedReg": "2014-12-01", 
    "description": "BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria has recently been identified on the Thailand-Cambodia border and more recently in parts of Thailand, Myanmar and Vietnam. There is concern that if this resistance were to spread, it would severely hamper malaria control and elimination efforts worldwide. Efforts are currently underway to intensify malaria control activities and ultimately eliminate malaria from Cambodia. To support these efforts, it is crucial to have a detailed picture of disease burden and its major determinants over time.\nMETHODS: An analysis of spatial and temporal data on clinical malaria in Cambodia collected by the National Centre for Parasitology, Entomology and Malaria Control (CNM) and the Department of Planning and Health Information, Ministry of Health Cambodia from 2004 to 2013 is presented.\nRESULTS: There has been a marked decrease of 81% in annual cases due to P. falciparum since 2009 coinciding with a rapid scale-up in village malaria workers (VMWs) and insecticide-treated bed nets (ITNs). Concurrently, the number of cases with Plasmodium vivax has greatly increased. It is estimated that there were around 112,000 total cases in 2012, 2.8 times greater than the WHO estimate for that year, and 68,000 in 2013 (an annual parasite incidence (API) of 4.6/1000). With the scale-up of VMWs, numbers of patients presenting to government facilities did not fall and it appears likely that those who saw VMWs had previously accessed healthcare in the private sector. Malaria mortality has decreased, particularly in areas with VMWs. There has been a marked decrease in cases in parts of western Cambodia, especially in Pailin and Battambang Provinces. In the northeast, the fall in malaria burden has been more modest, this area having the highest API in 2013.\nCONCLUSION: The clinical burden of falciparum malaria in most areas of Cambodia has greatly decreased from 2009 to 2013, associated with roll-out of ITNs and VMWs. Numbers of cases with P. vivax have increased. Possible reasons for these trends are discussed and areas requiring further study are highlighted. Although malaria surveillance data are prone to collection bias and tend to underestimate disease burden, the finding of similar trends in two independent datasets in this study greatly increased the robustness of the findings.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1475-2875-13-385", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3642719", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030597", 
        "issn": [
          "1475-2875"
        ], 
        "name": "Malaria Journal", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "name": "Spatial and temporal epidemiology of clinical malaria in Cambodia 2004\u20132013", 
    "pagination": "385", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8c964ca2623de135340755fcb5f68d7ddf0ebc445886249ce106a5e7ad19f9c4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25266007"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101139802"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1475-2875-13-385"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1029511199"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1475-2875-13-385", 
      "https://app.dimensions.ai/details/publication/pub.1029511199"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000513.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1475-2875-13-385"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-385'


 

This table displays all metadata directly associated to this object as RDF triples.

229 TRIPLES      21 PREDICATES      52 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1475-2875-13-385 schema:about N04ae7b403bad49cb81bcc4cbd5da0f15
2 N76897df0278042ec97474fd45aef1b10
3 N9d3e71d3526846638acb0569b48e3963
4 Nadd8b45a4eeb48b986ab3a9a05d3cc44
5 Naebf605b789a4e3db563682c4ba5519e
6 Ndd41ffc88dc74397a425101c6379a74e
7 Ne7f8725d4bcf46e7813f3bb3e3425344
8 anzsrc-for:11
9 anzsrc-for:1117
10 schema:author N8ab7b610bd154b1f85461028add696f9
11 schema:citation sg:pub.10.1186/1475-2875-11-355
12 sg:pub.10.1186/1475-2875-6-37
13 sg:pub.10.1186/1475-2875-7-96
14 sg:pub.10.1186/1475-2875-8-142
15 sg:pub.10.1186/1475-2875-8-31
16 https://app.dimensions.ai/details/publication/pub.1077389654
17 https://doi.org/10.1002/ddr.20344
18 https://doi.org/10.1016/s0140-6736(10)61963-0
19 https://doi.org/10.1016/s0140-6736(12)60484-x
20 https://doi.org/10.1016/s1473-3099(12)70181-0
21 https://doi.org/10.1056/nejmp1108322
22 https://doi.org/10.1155/2013/363417
23 https://doi.org/10.1371/journal.pmed.1001040
24 https://doi.org/10.1371/journal.pone.0037166
25 https://doi.org/10.1371/journal.pone.0057689
26 https://doi.org/10.1890/08-1022.1
27 schema:datePublished 2014-12
28 schema:datePublishedReg 2014-12-01
29 schema:description BACKGROUND: Artemisinin-resistant Plasmodium falciparum malaria has recently been identified on the Thailand-Cambodia border and more recently in parts of Thailand, Myanmar and Vietnam. There is concern that if this resistance were to spread, it would severely hamper malaria control and elimination efforts worldwide. Efforts are currently underway to intensify malaria control activities and ultimately eliminate malaria from Cambodia. To support these efforts, it is crucial to have a detailed picture of disease burden and its major determinants over time. METHODS: An analysis of spatial and temporal data on clinical malaria in Cambodia collected by the National Centre for Parasitology, Entomology and Malaria Control (CNM) and the Department of Planning and Health Information, Ministry of Health Cambodia from 2004 to 2013 is presented. RESULTS: There has been a marked decrease of 81% in annual cases due to P. falciparum since 2009 coinciding with a rapid scale-up in village malaria workers (VMWs) and insecticide-treated bed nets (ITNs). Concurrently, the number of cases with Plasmodium vivax has greatly increased. It is estimated that there were around 112,000 total cases in 2012, 2.8 times greater than the WHO estimate for that year, and 68,000 in 2013 (an annual parasite incidence (API) of 4.6/1000). With the scale-up of VMWs, numbers of patients presenting to government facilities did not fall and it appears likely that those who saw VMWs had previously accessed healthcare in the private sector. Malaria mortality has decreased, particularly in areas with VMWs. There has been a marked decrease in cases in parts of western Cambodia, especially in Pailin and Battambang Provinces. In the northeast, the fall in malaria burden has been more modest, this area having the highest API in 2013. CONCLUSION: The clinical burden of falciparum malaria in most areas of Cambodia has greatly decreased from 2009 to 2013, associated with roll-out of ITNs and VMWs. Numbers of cases with P. vivax have increased. Possible reasons for these trends are discussed and areas requiring further study are highlighted. Although malaria surveillance data are prone to collection bias and tend to underestimate disease burden, the finding of similar trends in two independent datasets in this study greatly increased the robustness of the findings.
30 schema:genre research_article
31 schema:inLanguage en
32 schema:isAccessibleForFree true
33 schema:isPartOf N56475f7af8414838b5f5a15e3e3e9ad0
34 N768df059072a48109b69a53379b597e5
35 sg:journal.1030597
36 schema:name Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013
37 schema:pagination 385
38 schema:productId N27496b33db4a4501be08f48500d047dd
39 N4f2a1d39cec34d348dc0a7065fbdd832
40 N91fb1585f15d4ac592d99b5c72385ce5
41 Nb42293df399445ebb229879b25d51fbd
42 Ncd22b88fc6c1466186a11d7ceb59ff0f
43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029511199
44 https://doi.org/10.1186/1475-2875-13-385
45 schema:sdDatePublished 2019-04-10T18:20
46 schema:sdLicense https://scigraph.springernature.com/explorer/license/
47 schema:sdPublisher Nd396df49041d496681c046f883b349b5
48 schema:url http://link.springer.com/10.1186%2F1475-2875-13-385
49 sgo:license sg:explorer/license/
50 sgo:sdDataset articles
51 rdf:type schema:ScholarlyArticle
52 N00a12d7a4d904eada92c868fc1f72135 rdf:first sg:person.01302212135.78
53 rdf:rest N4b485f9449a14b7bbe2c1e4c536ccdb3
54 N03d65e1af0184f6487e4ddca98c76899 rdf:first sg:person.0707431241.45
55 rdf:rest N80dda097d7e44749acfd3cc7a6ddf26a
56 N04ae7b403bad49cb81bcc4cbd5da0f15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
57 schema:name Spatio-Temporal Analysis
58 rdf:type schema:DefinedTerm
59 N27496b33db4a4501be08f48500d047dd schema:name doi
60 schema:value 10.1186/1475-2875-13-385
61 rdf:type schema:PropertyValue
62 N309298d591aa4cb5a42120f7ac8c757c rdf:first sg:person.013570515662.78
63 rdf:rest N00a12d7a4d904eada92c868fc1f72135
64 N3c57b45dd9a14a4da6a349e4c6e970b0 rdf:first N5303a8f85f704dd786e5ec248e875d5f
65 rdf:rest Nb96d529d729841e3bc48792659e03169
66 N4b485f9449a14b7bbe2c1e4c536ccdb3 rdf:first sg:person.0736216222.41
67 rdf:rest rdf:nil
68 N4f2a1d39cec34d348dc0a7065fbdd832 schema:name readcube_id
69 schema:value 8c964ca2623de135340755fcb5f68d7ddf0ebc445886249ce106a5e7ad19f9c4
70 rdf:type schema:PropertyValue
71 N5303a8f85f704dd786e5ec248e875d5f schema:affiliation https://www.grid.ac/institutes/grid.10223.32
72 schema:familyName Canavati de la Torre
73 schema:givenName Sara E
74 rdf:type schema:Person
75 N5342aeda91c54cd3953146fabb8792b2 rdf:first sg:person.01336750330.01
76 rdf:rest N3c57b45dd9a14a4da6a349e4c6e970b0
77 N56475f7af8414838b5f5a15e3e3e9ad0 schema:issueNumber 1
78 rdf:type schema:PublicationIssue
79 N76897df0278042ec97474fd45aef1b10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Malaria, Falciparum
81 rdf:type schema:DefinedTerm
82 N768df059072a48109b69a53379b597e5 schema:volumeNumber 13
83 rdf:type schema:PublicationVolume
84 N80dda097d7e44749acfd3cc7a6ddf26a rdf:first sg:person.01073062625.06
85 rdf:rest Nfea2205ad4e24f0a9807d1eda778044d
86 N8ab7b610bd154b1f85461028add696f9 rdf:first sg:person.013727356027.81
87 rdf:rest N03d65e1af0184f6487e4ddca98c76899
88 N91fb1585f15d4ac592d99b5c72385ce5 schema:name pubmed_id
89 schema:value 25266007
90 rdf:type schema:PropertyValue
91 N9d3e71d3526846638acb0569b48e3963 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Prevalence
93 rdf:type schema:DefinedTerm
94 Na534002462d14cc3b7742536d2a97b6f rdf:first sg:person.01162317707.88
95 rdf:rest N309298d591aa4cb5a42120f7ac8c757c
96 Nadd8b45a4eeb48b986ab3a9a05d3cc44 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Malaria, Vivax
98 rdf:type schema:DefinedTerm
99 Naebf605b789a4e3db563682c4ba5519e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Communicable Disease Control
101 rdf:type schema:DefinedTerm
102 Nb42293df399445ebb229879b25d51fbd schema:name dimensions_id
103 schema:value pub.1029511199
104 rdf:type schema:PropertyValue
105 Nb96d529d729841e3bc48792659e03169 rdf:first sg:person.01332073522.49
106 rdf:rest Na534002462d14cc3b7742536d2a97b6f
107 Ncd22b88fc6c1466186a11d7ceb59ff0f schema:name nlm_unique_id
108 schema:value 101139802
109 rdf:type schema:PropertyValue
110 Nd396df49041d496681c046f883b349b5 schema:name Springer Nature - SN SciGraph project
111 rdf:type schema:Organization
112 Ndd41ffc88dc74397a425101c6379a74e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Cambodia
114 rdf:type schema:DefinedTerm
115 Ne7f8725d4bcf46e7813f3bb3e3425344 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Humans
117 rdf:type schema:DefinedTerm
118 Nfea2205ad4e24f0a9807d1eda778044d rdf:first sg:person.01202660364.57
119 rdf:rest N5342aeda91c54cd3953146fabb8792b2
120 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
121 schema:name Medical and Health Sciences
122 rdf:type schema:DefinedTerm
123 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
124 schema:name Public Health and Health Services
125 rdf:type schema:DefinedTerm
126 sg:grant.3642719 http://pending.schema.org/fundedItem sg:pub.10.1186/1475-2875-13-385
127 rdf:type schema:MonetaryGrant
128 sg:journal.1030597 schema:issn 1475-2875
129 schema:name Malaria Journal
130 rdf:type schema:Periodical
131 sg:person.01073062625.06 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
132 schema:familyName Ly
133 schema:givenName Po
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073062625.06
135 rdf:type schema:Person
136 sg:person.01162317707.88 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
137 schema:familyName Dondorp
138 schema:givenName Arjen M
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162317707.88
140 rdf:type schema:Person
141 sg:person.01202660364.57 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
142 schema:familyName Bunkea
143 schema:givenName Tol
144 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202660364.57
145 rdf:type schema:Person
146 sg:person.01302212135.78 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
147 schema:familyName White
148 schema:givenName Lisa J
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302212135.78
150 rdf:type schema:Person
151 sg:person.01332073522.49 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
152 schema:familyName White
153 schema:givenName Nicholas J
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332073522.49
155 rdf:type schema:Person
156 sg:person.01336750330.01 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
157 schema:familyName Ngor
158 schema:givenName Pengby
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336750330.01
160 rdf:type schema:Person
161 sg:person.013570515662.78 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
162 schema:familyName Day
163 schema:givenName Nicholas PJ
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013570515662.78
165 rdf:type schema:Person
166 sg:person.013727356027.81 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
167 schema:familyName Maude
168 schema:givenName Richard J
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013727356027.81
170 rdf:type schema:Person
171 sg:person.0707431241.45 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
172 schema:familyName Nguon
173 schema:givenName Chea
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707431241.45
175 rdf:type schema:Person
176 sg:person.0736216222.41 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
177 schema:familyName Chuor
178 schema:givenName Char Meng
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41
180 rdf:type schema:Person
181 sg:pub.10.1186/1475-2875-11-355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028137830
182 https://doi.org/10.1186/1475-2875-11-355
183 rdf:type schema:CreativeWork
184 sg:pub.10.1186/1475-2875-6-37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051443131
185 https://doi.org/10.1186/1475-2875-6-37
186 rdf:type schema:CreativeWork
187 sg:pub.10.1186/1475-2875-7-96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035357393
188 https://doi.org/10.1186/1475-2875-7-96
189 rdf:type schema:CreativeWork
190 sg:pub.10.1186/1475-2875-8-142 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052536364
191 https://doi.org/10.1186/1475-2875-8-142
192 rdf:type schema:CreativeWork
193 sg:pub.10.1186/1475-2875-8-31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018894370
194 https://doi.org/10.1186/1475-2875-8-31
195 rdf:type schema:CreativeWork
196 https://app.dimensions.ai/details/publication/pub.1077389654 schema:CreativeWork
197 https://doi.org/10.1002/ddr.20344 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024068330
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/s0140-6736(10)61963-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026127494
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/s0140-6736(12)60484-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053009002
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/s1473-3099(12)70181-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047536348
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1056/nejmp1108322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020900302
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1155/2013/363417 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038609963
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1371/journal.pmed.1001040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026505822
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1371/journal.pone.0037166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044060061
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1371/journal.pone.0057689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001233277
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1890/08-1022.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010996559
216 rdf:type schema:CreativeWork
217 https://www.grid.ac/institutes/grid.10223.32 schema:alternateName Mahidol University
218 schema:name Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
219 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
220 National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
221 rdf:type schema:Organization
222 https://www.grid.ac/institutes/grid.452707.3 schema:alternateName Cambodia National Malaria Center
223 schema:name Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
224 National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
225 rdf:type schema:Organization
226 https://www.grid.ac/institutes/grid.4991.5 schema:alternateName University of Oxford
227 schema:name Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK
228 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
229 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...