Association between malaria control and paediatric blood transfusions in rural Zambia: an interrupted time-series analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-09-26

AUTHORS

Alison B Comfort, Janneke H van Dijk, Sungano Mharakurwa, Kathryn Stillman, Benjamin Johns, Payal Hathi, Sonali Korde, Allen S Craig, Nancy Nachbar, Yann Derriennic, Rose Gabert, Philip E Thuma

ABSTRACT

BackgroundBlood transfusions can reduce mortality among children with severe malarial anaemia, but there is limited evidence quantifying the relationship between paediatric malaria and blood transfusions. This study explores the extent to which the use of paediatric blood transfusions is affected by the number of paediatric malaria visits and admissions. It assesses whether the scale-up of malaria control interventions in a facility catchment area explains the use of paediatric blood transfusions.MethodsThe study was conducted at a referral hospital for 13 rural health centres in rural Zambia. Data were used from facility and patient records covering all paediatric malaria admissions from 2000 to 2008. An interrupted time series analysis using an autoregression-moving-average model was conducted to assess the relationship between paediatric malaria outpatient visits and admissions and the use of paediatric blood transfusions. Further investigation explored whether the use of paediatric blood transfusions over time was consistent with the roll out of malaria control interventions in the hospital catchment area.ResultsFor each additional paediatric malaria outpatient visit, there were 0.07 additional paediatric blood transfusions (95% CI 0.01-0.13; p < 0.05). For each additional paediatric admission for severe malarial anaemia, there were 1.09 additional paediatric blood transfusions (95% CI 0.95-1.23; p < 0.01). There were 19.1 fewer paediatric blood transfusions per month during the 2004–2006 malaria control period (95% CI 12.1-26.0; p < 0.01), a 50% reduction compared to the preceding period when malaria control was relatively limited. During the 2007–2008 malaria control period, there were 27.5 fewer paediatric blood transfusions per month (95% CI 14.6-40.3; p < 0.01), representing a 72% decline compared to the period with limited malaria control.ConclusionsPaediatric admissions for severe malarial anaemia largely explain total use of paediatric blood transfusions. The reduction in paediatric blood transfusions is consistent with the timing of the malaria control interventions. Malaria control seems to influence the use of paediatric blood transfusions by reducing the number of paediatric admissions for severe malarial anaemia. Reduced use of blood transfusions could benefit other areas of the health system through greater blood availability, particularly where supply is limited. More... »

PAGES

383

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1475-2875-13-383

DOI

http://dx.doi.org/10.1186/1475-2875-13-383

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050638327

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25261276


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anemia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Transfusion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hospitalization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant, Newborn", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interrupted Time Series Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zambia", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Abt Associates, International Health Division, Cambridge, MA, USA", 
          "id": "http://www.grid.ac/institutes/grid.417585.a", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Comfort", 
        "givenName": "Alison B", 
        "id": "sg:person.01065225761.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065225761.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Clinical Research Department, Macha Research Trust, Choma, Zambia", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Clinical Research Department, Macha Research Trust, Choma, Zambia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Dijk", 
        "givenName": "Janneke H", 
        "id": "sg:person.0722312532.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722312532.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins Malaria Research Institute, Malaria Research Department, Macha Research Trust, Choma, Zambia", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Johns Hopkins Malaria Research Institute, Malaria Research Department, Macha Research Trust, Choma, Zambia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mharakurwa", 
        "givenName": "Sungano", 
        "id": "sg:person.01170566746.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170566746.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abt Associates, International Health Division, Cambridge, MA, USA", 
          "id": "http://www.grid.ac/institutes/grid.417585.a", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stillman", 
        "givenName": "Kathryn", 
        "id": "sg:person.01263256474.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263256474.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abt Associates, International Health Division, Cambridge, MA, USA", 
          "id": "http://www.grid.ac/institutes/grid.417585.a", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Johns", 
        "givenName": "Benjamin", 
        "id": "sg:person.0602446103.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602446103.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abt Associates, International Health Division, Cambridge, MA, USA", 
          "id": "http://www.grid.ac/institutes/grid.417585.a", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hathi", 
        "givenName": "Payal", 
        "id": "sg:person.01361473234.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361473234.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "President\u2019s Malaria Initiative, Bureau of Global Health, USAID, Washington District of Columbia, Washington, DC, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "President\u2019s Malaria Initiative, Bureau of Global Health, USAID, Washington District of Columbia, Washington, DC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Korde", 
        "givenName": "Sonali", 
        "id": "sg:person.0605765574.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605765574.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA", 
          "id": "http://www.grid.ac/institutes/grid.467642.5", 
          "name": [
            "President\u2019s Malaria Initiative, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Lusaka, Zambia", 
            "Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Craig", 
        "givenName": "Allen S", 
        "id": "sg:person.01264211001.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264211001.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abt Associates, International Health Division, Cambridge, MA, USA", 
          "id": "http://www.grid.ac/institutes/grid.417585.a", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nachbar", 
        "givenName": "Nancy", 
        "id": "sg:person.0654100774.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654100774.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abt Associates, International Health Division, Cambridge, MA, USA", 
          "id": "http://www.grid.ac/institutes/grid.417585.a", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Derriennic", 
        "givenName": "Yann", 
        "id": "sg:person.0722214174.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722214174.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA", 
          "id": "http://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Abt Associates, International Health Division, Cambridge, MA, USA", 
            "The Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gabert", 
        "givenName": "Rose", 
        "id": "sg:person.01331371674.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331371674.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Macha Research Trust, Choma, Zambia", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Macha Research Trust, Choma, Zambia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thuma", 
        "givenName": "Philip E", 
        "id": "sg:person.01105620372.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105620372.26"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1475-2875-8-19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002776716", 
          "https://doi.org/10.1186/1475-2875-8-19"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2431-9-51", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052874770", 
          "https://doi.org/10.1186/1471-2431-9-51"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms1879", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051406471", 
          "https://doi.org/10.1038/ncomms1879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-7-256", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013300534", 
          "https://doi.org/10.1186/1475-2875-7-256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc2183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029594337", 
          "https://doi.org/10.1186/cc2183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-8-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043427717", 
          "https://doi.org/10.1186/1475-2875-8-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-7-25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014739997", 
          "https://doi.org/10.1186/1475-2875-7-25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-437", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026644797", 
          "https://doi.org/10.1186/1475-2875-11-437"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-09-26", 
    "datePublishedReg": "2014-09-26", 
    "description": "BackgroundBlood transfusions can reduce mortality among children with severe malarial anaemia, but there is limited evidence quantifying the relationship between paediatric malaria and blood transfusions. This study explores the extent to which the use of paediatric blood transfusions is affected by the number of paediatric malaria visits and admissions. It assesses whether the scale-up of malaria control interventions in a facility catchment area explains the use of paediatric blood transfusions.MethodsThe study was conducted at a referral hospital for 13 rural health centres in rural Zambia. Data were used from facility and patient records covering all paediatric malaria admissions from 2000 to 2008. An interrupted time series analysis using an autoregression-moving-average model was conducted to assess the relationship between paediatric malaria outpatient visits and admissions and the use of paediatric blood transfusions. Further investigation explored whether the use of paediatric blood transfusions over time was consistent with the roll out of malaria control interventions in the hospital catchment area.ResultsFor each additional paediatric malaria outpatient visit, there were 0.07 additional paediatric blood transfusions (95% CI 0.01-0.13; p < 0.05). For each additional paediatric admission for severe malarial anaemia, there were 1.09 additional paediatric blood transfusions (95% CI 0.95-1.23; p < 0.01). There were 19.1 fewer paediatric blood transfusions per month during the 2004\u20132006 malaria control period (95% CI 12.1-26.0; p < 0.01), a 50% reduction compared to the preceding period when malaria control was relatively limited. During the 2007\u20132008 malaria control period, there were 27.5 fewer paediatric blood transfusions per month (95% CI 14.6-40.3; p < 0.01), representing a 72% decline compared to the period with limited malaria control.ConclusionsPaediatric admissions for severe malarial anaemia largely explain total use of paediatric blood transfusions. The reduction in paediatric blood transfusions is consistent with the timing of the malaria control interventions. Malaria control seems to influence the use of paediatric blood transfusions by reducing the number of paediatric admissions for severe malarial anaemia. Reduced use of blood transfusions could benefit other areas of the health system through greater blood availability, particularly where supply is limited.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/1475-2875-13-383", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2697028", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2695864", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030597", 
        "issn": [
          "1475-2875"
        ], 
        "name": "Malaria Journal", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "keywords": [
      "paediatric blood transfusions", 
      "severe malarial anemia", 
      "malaria control interventions", 
      "blood transfusion", 
      "malarial anemia", 
      "interrupted time series analysis", 
      "malaria control", 
      "control interventions", 
      "outpatient visits", 
      "pediatric admissions", 
      "control period", 
      "rural health centers", 
      "hospital catchment area", 
      "paediatric malaria admissions", 
      "rural Zambia", 
      "facility catchment areas", 
      "BackgroundBlood transfusion", 
      "pediatric malaria", 
      "referral hospital", 
      "malaria admissions", 
      "health centers", 
      "transfusion", 
      "MethodsThe study", 
      "admission", 
      "blood availability", 
      "anemia", 
      "patient records", 
      "health system", 
      "limited evidence", 
      "visits", 
      "intervention", 
      "further investigation", 
      "months", 
      "total use", 
      "period", 
      "hospital", 
      "control", 
      "mortality", 
      "malaria", 
      "catchment area", 
      "time series analysis", 
      "children", 
      "study", 
      "association", 
      "use", 
      "Zambia", 
      "reduction", 
      "evidence", 
      "decline", 
      "records", 
      "center", 
      "relationship", 
      "number", 
      "area", 
      "timing", 
      "analysis", 
      "series analysis", 
      "extent", 
      "data", 
      "facilities", 
      "time", 
      "investigation", 
      "availability", 
      "model", 
      "supply", 
      "system", 
      "roll", 
      "average model"
    ], 
    "name": "Association between malaria control and paediatric blood transfusions in rural Zambia: an interrupted time-series analysis", 
    "pagination": "383", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050638327"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1475-2875-13-383"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25261276"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1475-2875-13-383", 
      "https://app.dimensions.ai/details/publication/pub.1050638327"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_617.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/1475-2875-13-383"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-383'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-383'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-383'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-13-383'


 

This table displays all metadata directly associated to this object as RDF triples.

299 TRIPLES      22 PREDICATES      112 URIs      96 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1475-2875-13-383 schema:about N187111099db942a0b32b10e8fdb5c228
2 N1fa132663b194ca3a6412ef84637659c
3 N2539b85f281142eea611b80df719f14a
4 N39ecf73e4f404ae0b5d0005dc53d7cee
5 N47ec558f73c84627a7ddc538976fbd1f
6 N4a05ba73d7654edfb806c90a5d4b5e55
7 N7033846720ff44c7aa6f329aa28d1ba6
8 N7770fccc6b8c4574926f80e11d0ba828
9 N9aa8239f72d34583873991e0cd4247f2
10 Nf96a6cacf3004c588496b955b9fc40a3
11 anzsrc-for:11
12 anzsrc-for:1117
13 schema:author N66021164f8f647328a24adf8a9bbebe4
14 schema:citation sg:pub.10.1038/ncomms1879
15 sg:pub.10.1186/1471-2431-9-51
16 sg:pub.10.1186/1475-2875-11-437
17 sg:pub.10.1186/1475-2875-7-25
18 sg:pub.10.1186/1475-2875-7-256
19 sg:pub.10.1186/1475-2875-8-19
20 sg:pub.10.1186/1475-2875-8-4
21 sg:pub.10.1186/cc2183
22 schema:datePublished 2014-09-26
23 schema:datePublishedReg 2014-09-26
24 schema:description BackgroundBlood transfusions can reduce mortality among children with severe malarial anaemia, but there is limited evidence quantifying the relationship between paediatric malaria and blood transfusions. This study explores the extent to which the use of paediatric blood transfusions is affected by the number of paediatric malaria visits and admissions. It assesses whether the scale-up of malaria control interventions in a facility catchment area explains the use of paediatric blood transfusions.MethodsThe study was conducted at a referral hospital for 13 rural health centres in rural Zambia. Data were used from facility and patient records covering all paediatric malaria admissions from 2000 to 2008. An interrupted time series analysis using an autoregression-moving-average model was conducted to assess the relationship between paediatric malaria outpatient visits and admissions and the use of paediatric blood transfusions. Further investigation explored whether the use of paediatric blood transfusions over time was consistent with the roll out of malaria control interventions in the hospital catchment area.ResultsFor each additional paediatric malaria outpatient visit, there were 0.07 additional paediatric blood transfusions (95% CI 0.01-0.13; p < 0.05). For each additional paediatric admission for severe malarial anaemia, there were 1.09 additional paediatric blood transfusions (95% CI 0.95-1.23; p < 0.01). There were 19.1 fewer paediatric blood transfusions per month during the 2004–2006 malaria control period (95% CI 12.1-26.0; p < 0.01), a 50% reduction compared to the preceding period when malaria control was relatively limited. During the 2007–2008 malaria control period, there were 27.5 fewer paediatric blood transfusions per month (95% CI 14.6-40.3; p < 0.01), representing a 72% decline compared to the period with limited malaria control.ConclusionsPaediatric admissions for severe malarial anaemia largely explain total use of paediatric blood transfusions. The reduction in paediatric blood transfusions is consistent with the timing of the malaria control interventions. Malaria control seems to influence the use of paediatric blood transfusions by reducing the number of paediatric admissions for severe malarial anaemia. Reduced use of blood transfusions could benefit other areas of the health system through greater blood availability, particularly where supply is limited.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree true
28 schema:isPartOf N8fa329558102414099a8a33c45695407
29 Ne477f3186a24488dbb98c5776ede6d04
30 sg:journal.1030597
31 schema:keywords BackgroundBlood transfusion
32 MethodsThe study
33 Zambia
34 admission
35 analysis
36 anemia
37 area
38 association
39 availability
40 average model
41 blood availability
42 blood transfusion
43 catchment area
44 center
45 children
46 control
47 control interventions
48 control period
49 data
50 decline
51 evidence
52 extent
53 facilities
54 facility catchment areas
55 further investigation
56 health centers
57 health system
58 hospital
59 hospital catchment area
60 interrupted time series analysis
61 intervention
62 investigation
63 limited evidence
64 malaria
65 malaria admissions
66 malaria control
67 malaria control interventions
68 malarial anemia
69 model
70 months
71 mortality
72 number
73 outpatient visits
74 paediatric blood transfusions
75 paediatric malaria admissions
76 patient records
77 pediatric admissions
78 pediatric malaria
79 period
80 records
81 reduction
82 referral hospital
83 relationship
84 roll
85 rural Zambia
86 rural health centers
87 series analysis
88 severe malarial anemia
89 study
90 supply
91 system
92 time
93 time series analysis
94 timing
95 total use
96 transfusion
97 use
98 visits
99 schema:name Association between malaria control and paediatric blood transfusions in rural Zambia: an interrupted time-series analysis
100 schema:pagination 383
101 schema:productId N727710796c8b424db58f40a9d7b3baea
102 N77e2ae7a83e0456babd89f4ab4fa245d
103 N800105dd2f0741209fa322cb1b7cbcb9
104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050638327
105 https://doi.org/10.1186/1475-2875-13-383
106 schema:sdDatePublished 2022-05-20T07:29
107 schema:sdLicense https://scigraph.springernature.com/explorer/license/
108 schema:sdPublisher N372790ed6619469089583982f83a22d4
109 schema:url https://doi.org/10.1186/1475-2875-13-383
110 sgo:license sg:explorer/license/
111 sgo:sdDataset articles
112 rdf:type schema:ScholarlyArticle
113 N0349c27723ea4110a21b9226ea403558 rdf:first sg:person.0602446103.50
114 rdf:rest Nae219f8117de4179b55e48f78194f831
115 N187111099db942a0b32b10e8fdb5c228 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Humans
117 rdf:type schema:DefinedTerm
118 N1a1573eea25948bc9b2e626a1688e331 rdf:first sg:person.01170566746.37
119 rdf:rest N20eeac206be8484ba13d240e1d92cf46
120 N1fa132663b194ca3a6412ef84637659c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Infant
122 rdf:type schema:DefinedTerm
123 N20eeac206be8484ba13d240e1d92cf46 rdf:first sg:person.01263256474.57
124 rdf:rest N0349c27723ea4110a21b9226ea403558
125 N2539b85f281142eea611b80df719f14a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Blood Transfusion
127 rdf:type schema:DefinedTerm
128 N2764a487e83e4b4c917edce1f0be7556 rdf:first sg:person.01105620372.26
129 rdf:rest rdf:nil
130 N372790ed6619469089583982f83a22d4 schema:name Springer Nature - SN SciGraph project
131 rdf:type schema:Organization
132 N39ecf73e4f404ae0b5d0005dc53d7cee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Child, Preschool
134 rdf:type schema:DefinedTerm
135 N3cf3edecc8584ad78ebf05af2d5bd548 rdf:first sg:person.0722214174.50
136 rdf:rest N8b4db17e58a1408c9f0b1d756d37d7b0
137 N47ec558f73c84627a7ddc538976fbd1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Hospitalization
139 rdf:type schema:DefinedTerm
140 N4a05ba73d7654edfb806c90a5d4b5e55 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Infant, Newborn
142 rdf:type schema:DefinedTerm
143 N66021164f8f647328a24adf8a9bbebe4 rdf:first sg:person.01065225761.86
144 rdf:rest N6dfcd82904ff4b509c23d211ec93042c
145 N6dfcd82904ff4b509c23d211ec93042c rdf:first sg:person.0722312532.10
146 rdf:rest N1a1573eea25948bc9b2e626a1688e331
147 N7033846720ff44c7aa6f329aa28d1ba6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Interrupted Time Series Analysis
149 rdf:type schema:DefinedTerm
150 N727710796c8b424db58f40a9d7b3baea schema:name dimensions_id
151 schema:value pub.1050638327
152 rdf:type schema:PropertyValue
153 N7770fccc6b8c4574926f80e11d0ba828 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Malaria
155 rdf:type schema:DefinedTerm
156 N77e2ae7a83e0456babd89f4ab4fa245d schema:name pubmed_id
157 schema:value 25261276
158 rdf:type schema:PropertyValue
159 N79252417803d47d8badea7acd0afa9f4 rdf:first sg:person.01264211001.18
160 rdf:rest N8900922a1eea43e5b8bc7503bef684b7
161 N800105dd2f0741209fa322cb1b7cbcb9 schema:name doi
162 schema:value 10.1186/1475-2875-13-383
163 rdf:type schema:PropertyValue
164 N8900922a1eea43e5b8bc7503bef684b7 rdf:first sg:person.0654100774.16
165 rdf:rest N3cf3edecc8584ad78ebf05af2d5bd548
166 N8b4db17e58a1408c9f0b1d756d37d7b0 rdf:first sg:person.01331371674.42
167 rdf:rest N2764a487e83e4b4c917edce1f0be7556
168 N8fa329558102414099a8a33c45695407 schema:volumeNumber 13
169 rdf:type schema:PublicationVolume
170 N9aa8239f72d34583873991e0cd4247f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Anemia
172 rdf:type schema:DefinedTerm
173 Nae219f8117de4179b55e48f78194f831 rdf:first sg:person.01361473234.98
174 rdf:rest Neb82a900cf244e38960b9208825eae3c
175 Ne477f3186a24488dbb98c5776ede6d04 schema:issueNumber 1
176 rdf:type schema:PublicationIssue
177 Neb82a900cf244e38960b9208825eae3c rdf:first sg:person.0605765574.70
178 rdf:rest N79252417803d47d8badea7acd0afa9f4
179 Nf96a6cacf3004c588496b955b9fc40a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Zambia
181 rdf:type schema:DefinedTerm
182 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
183 schema:name Medical and Health Sciences
184 rdf:type schema:DefinedTerm
185 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
186 schema:name Public Health and Health Services
187 rdf:type schema:DefinedTerm
188 sg:grant.2695864 http://pending.schema.org/fundedItem sg:pub.10.1186/1475-2875-13-383
189 rdf:type schema:MonetaryGrant
190 sg:grant.2697028 http://pending.schema.org/fundedItem sg:pub.10.1186/1475-2875-13-383
191 rdf:type schema:MonetaryGrant
192 sg:journal.1030597 schema:issn 1475-2875
193 schema:name Malaria Journal
194 schema:publisher Springer Nature
195 rdf:type schema:Periodical
196 sg:person.01065225761.86 schema:affiliation grid-institutes:grid.417585.a
197 schema:familyName Comfort
198 schema:givenName Alison B
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065225761.86
200 rdf:type schema:Person
201 sg:person.01105620372.26 schema:affiliation grid-institutes:None
202 schema:familyName Thuma
203 schema:givenName Philip E
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105620372.26
205 rdf:type schema:Person
206 sg:person.01170566746.37 schema:affiliation grid-institutes:None
207 schema:familyName Mharakurwa
208 schema:givenName Sungano
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170566746.37
210 rdf:type schema:Person
211 sg:person.01263256474.57 schema:affiliation grid-institutes:grid.417585.a
212 schema:familyName Stillman
213 schema:givenName Kathryn
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263256474.57
215 rdf:type schema:Person
216 sg:person.01264211001.18 schema:affiliation grid-institutes:grid.467642.5
217 schema:familyName Craig
218 schema:givenName Allen S
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264211001.18
220 rdf:type schema:Person
221 sg:person.01331371674.42 schema:affiliation grid-institutes:grid.34477.33
222 schema:familyName Gabert
223 schema:givenName Rose
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331371674.42
225 rdf:type schema:Person
226 sg:person.01361473234.98 schema:affiliation grid-institutes:grid.417585.a
227 schema:familyName Hathi
228 schema:givenName Payal
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361473234.98
230 rdf:type schema:Person
231 sg:person.0602446103.50 schema:affiliation grid-institutes:grid.417585.a
232 schema:familyName Johns
233 schema:givenName Benjamin
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602446103.50
235 rdf:type schema:Person
236 sg:person.0605765574.70 schema:affiliation grid-institutes:None
237 schema:familyName Korde
238 schema:givenName Sonali
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605765574.70
240 rdf:type schema:Person
241 sg:person.0654100774.16 schema:affiliation grid-institutes:grid.417585.a
242 schema:familyName Nachbar
243 schema:givenName Nancy
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654100774.16
245 rdf:type schema:Person
246 sg:person.0722214174.50 schema:affiliation grid-institutes:grid.417585.a
247 schema:familyName Derriennic
248 schema:givenName Yann
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722214174.50
250 rdf:type schema:Person
251 sg:person.0722312532.10 schema:affiliation grid-institutes:None
252 schema:familyName van Dijk
253 schema:givenName Janneke H
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722312532.10
255 rdf:type schema:Person
256 sg:pub.10.1038/ncomms1879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051406471
257 https://doi.org/10.1038/ncomms1879
258 rdf:type schema:CreativeWork
259 sg:pub.10.1186/1471-2431-9-51 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052874770
260 https://doi.org/10.1186/1471-2431-9-51
261 rdf:type schema:CreativeWork
262 sg:pub.10.1186/1475-2875-11-437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026644797
263 https://doi.org/10.1186/1475-2875-11-437
264 rdf:type schema:CreativeWork
265 sg:pub.10.1186/1475-2875-7-25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014739997
266 https://doi.org/10.1186/1475-2875-7-25
267 rdf:type schema:CreativeWork
268 sg:pub.10.1186/1475-2875-7-256 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013300534
269 https://doi.org/10.1186/1475-2875-7-256
270 rdf:type schema:CreativeWork
271 sg:pub.10.1186/1475-2875-8-19 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002776716
272 https://doi.org/10.1186/1475-2875-8-19
273 rdf:type schema:CreativeWork
274 sg:pub.10.1186/1475-2875-8-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043427717
275 https://doi.org/10.1186/1475-2875-8-4
276 rdf:type schema:CreativeWork
277 sg:pub.10.1186/cc2183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029594337
278 https://doi.org/10.1186/cc2183
279 rdf:type schema:CreativeWork
280 grid-institutes:None schema:alternateName Clinical Research Department, Macha Research Trust, Choma, Zambia
281 Johns Hopkins Malaria Research Institute, Malaria Research Department, Macha Research Trust, Choma, Zambia
282 Macha Research Trust, Choma, Zambia
283 President’s Malaria Initiative, Bureau of Global Health, USAID, Washington District of Columbia, Washington, DC, USA
284 schema:name Clinical Research Department, Macha Research Trust, Choma, Zambia
285 Johns Hopkins Malaria Research Institute, Malaria Research Department, Macha Research Trust, Choma, Zambia
286 Macha Research Trust, Choma, Zambia
287 President’s Malaria Initiative, Bureau of Global Health, USAID, Washington District of Columbia, Washington, DC, USA
288 rdf:type schema:Organization
289 grid-institutes:grid.34477.33 schema:alternateName The Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA
290 schema:name Abt Associates, International Health Division, Cambridge, MA, USA
291 The Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA
292 rdf:type schema:Organization
293 grid-institutes:grid.417585.a schema:alternateName Abt Associates, International Health Division, Cambridge, MA, USA
294 schema:name Abt Associates, International Health Division, Cambridge, MA, USA
295 rdf:type schema:Organization
296 grid-institutes:grid.467642.5 schema:alternateName Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
297 schema:name Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
298 President’s Malaria Initiative, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Lusaka, Zambia
299 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...