An innovative tool for moving malaria PCR detection of parasite reservoir into the field View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Lydie Canier, Nimol Khim, Saorin Kim, Vincent Sluydts, Somony Heng, Dany Dourng, Rotha Eam, Sophy Chy, Chanra Khean, Kaknika Loch, Malen Ken, Hokkean Lim, Sovannaroath Siv, Sochantha Tho, Pascal Masse-Navette, Charlotte Gryseels, Sambunny Uk, Karel Van Roey, Koen Peeters Grietens, Mao Sokny, Boukheng Thavrin, Char Meng Chuor, Vincent Deubel, Lies Durnez, Marc Coosemans, Didier Ménard

ABSTRACT

BACKGROUND: To achieve the goal of malaria elimination in low transmission areas such as in Cambodia, new, inexpensive, high-throughput diagnostic tools for identifying very low parasite densities in asymptomatic carriers are required. This will enable a switch from passive to active malaria case detection in the field. METHODS: DNA extraction and real-time PCR assays were implemented in an "in-house" designed mobile laboratory allowing implementation of a robust, sensitive and rapid malaria diagnostic strategy in the field. This tool was employed in a survey organized in the context of the MalaResT project (NCT01663831). RESULTS: The real-time PCR screening and species identification assays were performed in the mobile laboratory between October and November 2012, in Rattanakiri Province, to screen approximately 5,000 individuals in less than four weeks and treat parasite carriers within 24-48 hours after sample collection. An average of 240 clinical samples (and 40 quality control samples) was tested every day, six/seven days per week. Some 97.7% of the results were available <24 hours after the collection. A total of 4.9% were positive for malaria. Plasmodium vivax was present in 61.1% of the positive samples, Plasmodium falciparum in 45.9%, Plasmodium malariae in 7.0% and Plasmodium ovale in 2.0%. CONCLUSIONS: The operational success of this diagnostic set-up proved that molecular testing and subsequent treatment is logistically achievable in field settings. This will allow the detection of clusters of asymptomatic carriers and to provide useful epidemiological information. Fast results will be of great help for staff in the field to track and treat asymptomatic parasitaemic cases. The concept of the mobile laboratory could be extended to other countries for the molecular detection of malaria or other pathogens, or to culture vivax parasites, which does not support long-time delay between sample collection and culture. More... »

PAGES

405

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1475-2875-12-405

DOI

http://dx.doi.org/10.1186/1475-2875-12-405

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033011151

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24206649


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Asymptomatic Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cambodia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carrier State", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross-Sectional Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mass Screening", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Diagnostic Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Epidemiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Parasitology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plasmodium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Real-Time Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Canier", 
        "givenName": "Lydie", 
        "id": "sg:person.01214612750.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214612750.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khim", 
        "givenName": "Nimol", 
        "id": "sg:person.01246467524.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246467524.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Saorin", 
        "id": "sg:person.0667736036.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667736036.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sluydts", 
        "givenName": "Vincent", 
        "id": "sg:person.01175677125.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175677125.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia", 
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heng", 
        "givenName": "Somony", 
        "id": "sg:person.0601773124.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601773124.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dourng", 
        "givenName": "Dany", 
        "id": "sg:person.01372535440.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372535440.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eam", 
        "givenName": "Rotha", 
        "id": "sg:person.01174256532.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174256532.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chy", 
        "givenName": "Sophy", 
        "id": "sg:person.01351070036.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351070036.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khean", 
        "givenName": "Chanra", 
        "id": "sg:person.01310505132.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310505132.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Loch", 
        "givenName": "Kaknika", 
        "id": "sg:person.01356620332.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356620332.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ken", 
        "givenName": "Malen", 
        "id": "sg:person.01022772006.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022772006.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lim", 
        "givenName": "Hokkean", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siv", 
        "givenName": "Sovannaroath", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tho", 
        "givenName": "Sochantha", 
        "id": "sg:person.01015556032.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015556032.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masse-Navette", 
        "givenName": "Pascal", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gryseels", 
        "givenName": "Charlotte", 
        "id": "sg:person.0644245224.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644245224.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uk", 
        "givenName": "Sambunny", 
        "id": "sg:person.0615630713.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615630713.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Roey", 
        "givenName": "Karel", 
        "id": "sg:person.01246233032.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246233032.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grietens", 
        "givenName": "Koen Peeters", 
        "id": "sg:person.01271702207.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271702207.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sokny", 
        "givenName": "Mao", 
        "id": "sg:person.01046601205.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046601205.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thavrin", 
        "givenName": "Boukheng", 
        "id": "sg:person.0637055332.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637055332.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chuor", 
        "givenName": "Char Meng", 
        "id": "sg:person.0736216222.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Deubel", 
        "givenName": "Vincent", 
        "id": "sg:person.0677146672.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677146672.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Durnez", 
        "givenName": "Lies", 
        "id": "sg:person.01073106054.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073106054.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.5284.b", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium", 
            "Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coosemans", 
        "givenName": "Marc", 
        "id": "sg:person.0611227035.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611227035.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "M\u00e9nard", 
        "givenName": "Didier", 
        "id": "sg:person.0755351436.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755351436.01"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pmed.1000400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000364352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0057689", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001233277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(89)92800-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003174007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-10-323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007247238", 
          "https://doi.org/10.1186/1475-2875-10-323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/644781", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010516905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0808859", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011738279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0045797", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015974676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-12-26", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016660983", 
          "https://doi.org/10.1186/1475-2875-12-26"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.02156-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022150656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028011224", 
          "https://doi.org/10.1186/1475-2875-11-295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028137830", 
          "https://doi.org/10.1186/1475-2875-11-355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.00686-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036563581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1586/erm.12.53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039106176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmc0805011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041561416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-8-86", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042428786", 
          "https://doi.org/10.1186/1475-2875-8-86"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0034040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042850100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0166-6851(93)90077-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046601485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0166-6851(93)90077-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046601485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1473-3099(12)70181-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047536348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.actatropica.2011.02.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048785765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-6-37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051443131", 
          "https://doi.org/10.1186/1475-2875-6-37"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(12)60484-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053009002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.1999.60.687", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074467440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/1-59259-271-6:189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075088149", 
          "https://doi.org/10.1385/1-59259-271-6:189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.2007.77.119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077584378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.2008.78.217", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077604289"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-12", 
    "datePublishedReg": "2013-12-01", 
    "description": "BACKGROUND: To achieve the goal of malaria elimination in low transmission areas such as in Cambodia, new, inexpensive, high-throughput diagnostic tools for identifying very low parasite densities in asymptomatic carriers are required. This will enable a switch from passive to active malaria case detection in the field.\nMETHODS: DNA extraction and real-time PCR assays were implemented in an \"in-house\" designed mobile laboratory allowing implementation of a robust, sensitive and rapid malaria diagnostic strategy in the field. This tool was employed in a survey organized in the context of the MalaResT project (NCT01663831).\nRESULTS: The real-time PCR screening and species identification assays were performed in the mobile laboratory between October and November 2012, in Rattanakiri Province, to screen approximately 5,000 individuals in less than four weeks and treat parasite carriers within 24-48 hours after sample collection. An average of 240 clinical samples (and 40 quality control samples) was tested every day, six/seven days per week. Some 97.7% of the results were available <24 hours after the collection. A total of 4.9% were positive for malaria. Plasmodium vivax was present in 61.1% of the positive samples, Plasmodium falciparum in 45.9%, Plasmodium malariae in 7.0% and Plasmodium ovale in 2.0%.\nCONCLUSIONS: The operational success of this diagnostic set-up proved that molecular testing and subsequent treatment is logistically achievable in field settings. This will allow the detection of clusters of asymptomatic carriers and to provide useful epidemiological information. Fast results will be of great help for staff in the field to track and treat asymptomatic parasitaemic cases. The concept of the mobile laboratory could be extended to other countries for the molecular detection of malaria or other pathogens, or to culture vivax parasites, which does not support long-time delay between sample collection and culture.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1475-2875-12-405", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6585700", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030597", 
        "issn": [
          "1475-2875"
        ], 
        "name": "Malaria Journal", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "12"
      }
    ], 
    "name": "An innovative tool for moving malaria PCR detection of parasite reservoir into the field", 
    "pagination": "405", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9d4280d7c7307a5aa7fa69a0ef61711d74ef9c89c100d1dd4c2a764c76d373f9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24206649"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101139802"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1475-2875-12-405"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033011151"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1475-2875-12-405", 
      "https://app.dimensions.ai/details/publication/pub.1033011151"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000514.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1475-2875-12-405"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'


 

This table displays all metadata directly associated to this object as RDF triples.

391 TRIPLES      21 PREDICATES      68 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1475-2875-12-405 schema:about N025ec11b367e4ffca21ffa2933029047
2 N34aa4a9e87ad4bbe8caaea6f62aeb164
3 N6fc2601c9dbb44a9ad3a93341bc14078
4 N80e2ef1a51984a088d7b1c2638f82b78
5 Na960bdcb28b945cf8dd4fba847aed39f
6 Nc5d5bc23092e47c1bb028807b424ba88
7 Ncd98fe7dc8d34484931637e0ab151185
8 Nd394d609a8b04251be56823f9cf030b8
9 Nd4baaa709de34485a597ddbc90f9532e
10 Nd90f1372530746b78126485173724185
11 Nec70cedca23f4456b5615d0837a2b862
12 Nf97a771545ba4a5ca5d21a1490a20374
13 Nfab96f881657496b8db757a7ac5bb2d7
14 Nfbe1a51e0c4943f9b6563b9a041d4b29
15 anzsrc-for:11
16 anzsrc-for:1108
17 schema:author N9f182b3294a6438f935784f034abb01a
18 schema:citation sg:pub.10.1186/1475-2875-10-323
19 sg:pub.10.1186/1475-2875-11-295
20 sg:pub.10.1186/1475-2875-11-355
21 sg:pub.10.1186/1475-2875-12-26
22 sg:pub.10.1186/1475-2875-6-37
23 sg:pub.10.1186/1475-2875-8-86
24 sg:pub.10.1385/1-59259-271-6:189
25 https://doi.org/10.1016/0166-6851(93)90077-b
26 https://doi.org/10.1016/j.actatropica.2011.02.016
27 https://doi.org/10.1016/s0140-6736(12)60484-x
28 https://doi.org/10.1016/s0140-6736(89)92800-6
29 https://doi.org/10.1016/s1473-3099(12)70181-0
30 https://doi.org/10.1056/nejmc0805011
31 https://doi.org/10.1056/nejmoa0808859
32 https://doi.org/10.1086/644781
33 https://doi.org/10.1128/aac.00686-12
34 https://doi.org/10.1128/jcm.02156-10
35 https://doi.org/10.1371/journal.pmed.1000400
36 https://doi.org/10.1371/journal.pone.0034040
37 https://doi.org/10.1371/journal.pone.0045797
38 https://doi.org/10.1371/journal.pone.0057689
39 https://doi.org/10.1586/erm.12.53
40 https://doi.org/10.4269/ajtmh.1999.60.687
41 https://doi.org/10.4269/ajtmh.2007.77.119
42 https://doi.org/10.4269/ajtmh.2008.78.217
43 schema:datePublished 2013-12
44 schema:datePublishedReg 2013-12-01
45 schema:description BACKGROUND: To achieve the goal of malaria elimination in low transmission areas such as in Cambodia, new, inexpensive, high-throughput diagnostic tools for identifying very low parasite densities in asymptomatic carriers are required. This will enable a switch from passive to active malaria case detection in the field. METHODS: DNA extraction and real-time PCR assays were implemented in an "in-house" designed mobile laboratory allowing implementation of a robust, sensitive and rapid malaria diagnostic strategy in the field. This tool was employed in a survey organized in the context of the MalaResT project (NCT01663831). RESULTS: The real-time PCR screening and species identification assays were performed in the mobile laboratory between October and November 2012, in Rattanakiri Province, to screen approximately 5,000 individuals in less than four weeks and treat parasite carriers within 24-48 hours after sample collection. An average of 240 clinical samples (and 40 quality control samples) was tested every day, six/seven days per week. Some 97.7% of the results were available <24 hours after the collection. A total of 4.9% were positive for malaria. Plasmodium vivax was present in 61.1% of the positive samples, Plasmodium falciparum in 45.9%, Plasmodium malariae in 7.0% and Plasmodium ovale in 2.0%. CONCLUSIONS: The operational success of this diagnostic set-up proved that molecular testing and subsequent treatment is logistically achievable in field settings. This will allow the detection of clusters of asymptomatic carriers and to provide useful epidemiological information. Fast results will be of great help for staff in the field to track and treat asymptomatic parasitaemic cases. The concept of the mobile laboratory could be extended to other countries for the molecular detection of malaria or other pathogens, or to culture vivax parasites, which does not support long-time delay between sample collection and culture.
46 schema:genre research_article
47 schema:inLanguage en
48 schema:isAccessibleForFree true
49 schema:isPartOf Nca16f7c3ac3f418ab0dbd5185c42633d
50 Need4017b583242ce9c32150aa4256f2f
51 sg:journal.1030597
52 schema:name An innovative tool for moving malaria PCR detection of parasite reservoir into the field
53 schema:pagination 405
54 schema:productId N10229f280da846e79846d0ef98b91989
55 N5b798dd299ab49d0a5fbba89222f14a8
56 N64a8ea6149ed43ad8c744eb0f02c3927
57 Na6073df934ed4b2c8e18bb5c6a9d312e
58 Ne9a74f9cf2af4240accac201e39c9404
59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033011151
60 https://doi.org/10.1186/1475-2875-12-405
61 schema:sdDatePublished 2019-04-10T14:10
62 schema:sdLicense https://scigraph.springernature.com/explorer/license/
63 schema:sdPublisher N45a9597b44ef434fa648f9e2af6c7eeb
64 schema:url http://link.springer.com/10.1186%2F1475-2875-12-405
65 sgo:license sg:explorer/license/
66 sgo:sdDataset articles
67 rdf:type schema:ScholarlyArticle
68 N0010e6a79a2c42259b0e0558e992b4a6 rdf:first sg:person.0755351436.01
69 rdf:rest rdf:nil
70 N025ec11b367e4ffca21ffa2933029047 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Plasmodium
72 rdf:type schema:DefinedTerm
73 N10229f280da846e79846d0ef98b91989 schema:name nlm_unique_id
74 schema:value 101139802
75 rdf:type schema:PropertyValue
76 N1503d15498664d858ce3d48c164b9a3a rdf:first Nf55d51fa35d54f8a95171680863be7cc
77 rdf:rest N39504df4577f4bc4a3b20f5dd9d169fa
78 N18de735899524d55bbbcdec7c17a00c5 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
79 schema:familyName Siv
80 schema:givenName Sovannaroath
81 rdf:type schema:Person
82 N199020f686a9492fa081d825a2796cf9 rdf:first sg:person.01372535440.56
83 rdf:rest N5fb241d5b3f14af6a5b2570086f631df
84 N1c05086bb8a14b65a3a121ad24d0f3c4 rdf:first N4c8bdda746ae4393a3551060911d0e25
85 rdf:rest Na87502ef75934ac58f892a930c831d32
86 N1c24fad308bc4c99b7881739652a31a5 rdf:first sg:person.0677146672.97
87 rdf:rest Nb61c257de47148aeb61d48c076cd4cf9
88 N34aa4a9e87ad4bbe8caaea6f62aeb164 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Malaria
90 rdf:type schema:DefinedTerm
91 N39504df4577f4bc4a3b20f5dd9d169fa rdf:first N18de735899524d55bbbcdec7c17a00c5
92 rdf:rest Na8500925b50149d29eb2e00836578bdc
93 N413a32e0ecb84c91bef72a23a491d985 rdf:first sg:person.0637055332.82
94 rdf:rest N931e8067bd564c689a542d2857f357ce
95 N45a9597b44ef434fa648f9e2af6c7eeb schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 N4c8bdda746ae4393a3551060911d0e25 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
98 schema:familyName Masse-Navette
99 schema:givenName Pascal
100 rdf:type schema:Person
101 N5002e502d8e149d3a2249b4b9e108859 rdf:first sg:person.01356620332.84
102 rdf:rest N6098c35fe3ce4c7786ccf2f83da96f81
103 N530bd9d62eec41adb86d03a5f3da4f52 rdf:first sg:person.0601773124.81
104 rdf:rest N199020f686a9492fa081d825a2796cf9
105 N54a5307f9bbe492c94c46d5d4adeb848 rdf:first sg:person.01046601205.43
106 rdf:rest N413a32e0ecb84c91bef72a23a491d985
107 N5b798dd299ab49d0a5fbba89222f14a8 schema:name pubmed_id
108 schema:value 24206649
109 rdf:type schema:PropertyValue
110 N5fb241d5b3f14af6a5b2570086f631df rdf:first sg:person.01174256532.34
111 rdf:rest N6afee15759a24f8e88854e559738f7c8
112 N6098c35fe3ce4c7786ccf2f83da96f81 rdf:first sg:person.01022772006.34
113 rdf:rest N1503d15498664d858ce3d48c164b9a3a
114 N64a8ea6149ed43ad8c744eb0f02c3927 schema:name readcube_id
115 schema:value 9d4280d7c7307a5aa7fa69a0ef61711d74ef9c89c100d1dd4c2a764c76d373f9
116 rdf:type schema:PropertyValue
117 N6723f7b112254dc2a3a66013059301f4 rdf:first sg:person.0611227035.09
118 rdf:rest N0010e6a79a2c42259b0e0558e992b4a6
119 N6afee15759a24f8e88854e559738f7c8 rdf:first sg:person.01351070036.77
120 rdf:rest N6b358ec9e496488b852fec1767b529b6
121 N6b358ec9e496488b852fec1767b529b6 rdf:first sg:person.01310505132.08
122 rdf:rest N5002e502d8e149d3a2249b4b9e108859
123 N6fc2601c9dbb44a9ad3a93341bc14078 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Real-Time Polymerase Chain Reaction
125 rdf:type schema:DefinedTerm
126 N7512643a9cf34302af3dbc265675e610 rdf:first sg:person.01246233032.16
127 rdf:rest Nb0a293532eb84c04baabd9ab19d0c688
128 N80e2ef1a51984a088d7b1c2638f82b78 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Molecular Diagnostic Techniques
130 rdf:type schema:DefinedTerm
131 N8eed1326337a4c20a34b044d84db20e5 rdf:first sg:person.01175677125.45
132 rdf:rest N530bd9d62eec41adb86d03a5f3da4f52
133 N931e8067bd564c689a542d2857f357ce rdf:first sg:person.0736216222.41
134 rdf:rest N1c24fad308bc4c99b7881739652a31a5
135 N9789dde82d5c4b1ab9fc95187af26229 rdf:first sg:person.0667736036.69
136 rdf:rest N8eed1326337a4c20a34b044d84db20e5
137 N9f182b3294a6438f935784f034abb01a rdf:first sg:person.01214612750.28
138 rdf:rest Nf8ce00f6cbfc4eecae79e2b12eaebc54
139 Na6073df934ed4b2c8e18bb5c6a9d312e schema:name dimensions_id
140 schema:value pub.1033011151
141 rdf:type schema:PropertyValue
142 Na8500925b50149d29eb2e00836578bdc rdf:first sg:person.01015556032.71
143 rdf:rest N1c05086bb8a14b65a3a121ad24d0f3c4
144 Na87502ef75934ac58f892a930c831d32 rdf:first sg:person.0644245224.11
145 rdf:rest Nafb96068682b4405b29476f5c9ab8005
146 Na960bdcb28b945cf8dd4fba847aed39f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Asymptomatic Infections
148 rdf:type schema:DefinedTerm
149 Nafb96068682b4405b29476f5c9ab8005 rdf:first sg:person.0615630713.16
150 rdf:rest N7512643a9cf34302af3dbc265675e610
151 Nb0a293532eb84c04baabd9ab19d0c688 rdf:first sg:person.01271702207.08
152 rdf:rest N54a5307f9bbe492c94c46d5d4adeb848
153 Nb61c257de47148aeb61d48c076cd4cf9 rdf:first sg:person.01073106054.84
154 rdf:rest N6723f7b112254dc2a3a66013059301f4
155 Nc5d5bc23092e47c1bb028807b424ba88 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Parasitology
157 rdf:type schema:DefinedTerm
158 Nca16f7c3ac3f418ab0dbd5185c42633d schema:issueNumber 1
159 rdf:type schema:PublicationIssue
160 Ncd98fe7dc8d34484931637e0ab151185 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Sensitivity and Specificity
162 rdf:type schema:DefinedTerm
163 Nd394d609a8b04251be56823f9cf030b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Cross-Sectional Studies
165 rdf:type schema:DefinedTerm
166 Nd4baaa709de34485a597ddbc90f9532e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Time Factors
168 rdf:type schema:DefinedTerm
169 Nd90f1372530746b78126485173724185 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Humans
171 rdf:type schema:DefinedTerm
172 Ne9a74f9cf2af4240accac201e39c9404 schema:name doi
173 schema:value 10.1186/1475-2875-12-405
174 rdf:type schema:PropertyValue
175 Nec70cedca23f4456b5615d0837a2b862 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Carrier State
177 rdf:type schema:DefinedTerm
178 Need4017b583242ce9c32150aa4256f2f schema:volumeNumber 12
179 rdf:type schema:PublicationVolume
180 Nf55d51fa35d54f8a95171680863be7cc schema:affiliation https://www.grid.ac/institutes/grid.418537.c
181 schema:familyName Lim
182 schema:givenName Hokkean
183 rdf:type schema:Person
184 Nf8ce00f6cbfc4eecae79e2b12eaebc54 rdf:first sg:person.01246467524.81
185 rdf:rest N9789dde82d5c4b1ab9fc95187af26229
186 Nf97a771545ba4a5ca5d21a1490a20374 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Molecular Epidemiology
188 rdf:type schema:DefinedTerm
189 Nfab96f881657496b8db757a7ac5bb2d7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Mass Screening
191 rdf:type schema:DefinedTerm
192 Nfbe1a51e0c4943f9b6563b9a041d4b29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Cambodia
194 rdf:type schema:DefinedTerm
195 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
196 schema:name Medical and Health Sciences
197 rdf:type schema:DefinedTerm
198 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
199 schema:name Medical Microbiology
200 rdf:type schema:DefinedTerm
201 sg:grant.6585700 http://pending.schema.org/fundedItem sg:pub.10.1186/1475-2875-12-405
202 rdf:type schema:MonetaryGrant
203 sg:journal.1030597 schema:issn 1475-2875
204 schema:name Malaria Journal
205 rdf:type schema:Periodical
206 sg:person.01015556032.71 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
207 schema:familyName Tho
208 schema:givenName Sochantha
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015556032.71
210 rdf:type schema:Person
211 sg:person.01022772006.34 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
212 schema:familyName Ken
213 schema:givenName Malen
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022772006.34
215 rdf:type schema:Person
216 sg:person.01046601205.43 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
217 schema:familyName Sokny
218 schema:givenName Mao
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046601205.43
220 rdf:type schema:Person
221 sg:person.01073106054.84 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
222 schema:familyName Durnez
223 schema:givenName Lies
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073106054.84
225 rdf:type schema:Person
226 sg:person.01174256532.34 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
227 schema:familyName Eam
228 schema:givenName Rotha
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174256532.34
230 rdf:type schema:Person
231 sg:person.01175677125.45 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
232 schema:familyName Sluydts
233 schema:givenName Vincent
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175677125.45
235 rdf:type schema:Person
236 sg:person.01214612750.28 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
237 schema:familyName Canier
238 schema:givenName Lydie
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214612750.28
240 rdf:type schema:Person
241 sg:person.01246233032.16 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
242 schema:familyName Van Roey
243 schema:givenName Karel
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246233032.16
245 rdf:type schema:Person
246 sg:person.01246467524.81 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
247 schema:familyName Khim
248 schema:givenName Nimol
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246467524.81
250 rdf:type schema:Person
251 sg:person.01271702207.08 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
252 schema:familyName Grietens
253 schema:givenName Koen Peeters
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271702207.08
255 rdf:type schema:Person
256 sg:person.01310505132.08 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
257 schema:familyName Khean
258 schema:givenName Chanra
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310505132.08
260 rdf:type schema:Person
261 sg:person.01351070036.77 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
262 schema:familyName Chy
263 schema:givenName Sophy
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351070036.77
265 rdf:type schema:Person
266 sg:person.01356620332.84 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
267 schema:familyName Loch
268 schema:givenName Kaknika
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356620332.84
270 rdf:type schema:Person
271 sg:person.01372535440.56 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
272 schema:familyName Dourng
273 schema:givenName Dany
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372535440.56
275 rdf:type schema:Person
276 sg:person.0601773124.81 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
277 schema:familyName Heng
278 schema:givenName Somony
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601773124.81
280 rdf:type schema:Person
281 sg:person.0611227035.09 schema:affiliation https://www.grid.ac/institutes/grid.5284.b
282 schema:familyName Coosemans
283 schema:givenName Marc
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611227035.09
285 rdf:type schema:Person
286 sg:person.0615630713.16 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
287 schema:familyName Uk
288 schema:givenName Sambunny
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615630713.16
290 rdf:type schema:Person
291 sg:person.0637055332.82 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
292 schema:familyName Thavrin
293 schema:givenName Boukheng
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637055332.82
295 rdf:type schema:Person
296 sg:person.0644245224.11 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
297 schema:familyName Gryseels
298 schema:givenName Charlotte
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644245224.11
300 rdf:type schema:Person
301 sg:person.0667736036.69 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
302 schema:familyName Kim
303 schema:givenName Saorin
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667736036.69
305 rdf:type schema:Person
306 sg:person.0677146672.97 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
307 schema:familyName Deubel
308 schema:givenName Vincent
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677146672.97
310 rdf:type schema:Person
311 sg:person.0736216222.41 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
312 schema:familyName Chuor
313 schema:givenName Char Meng
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41
315 rdf:type schema:Person
316 sg:person.0755351436.01 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
317 schema:familyName Ménard
318 schema:givenName Didier
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755351436.01
320 rdf:type schema:Person
321 sg:pub.10.1186/1475-2875-10-323 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007247238
322 https://doi.org/10.1186/1475-2875-10-323
323 rdf:type schema:CreativeWork
324 sg:pub.10.1186/1475-2875-11-295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028011224
325 https://doi.org/10.1186/1475-2875-11-295
326 rdf:type schema:CreativeWork
327 sg:pub.10.1186/1475-2875-11-355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028137830
328 https://doi.org/10.1186/1475-2875-11-355
329 rdf:type schema:CreativeWork
330 sg:pub.10.1186/1475-2875-12-26 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016660983
331 https://doi.org/10.1186/1475-2875-12-26
332 rdf:type schema:CreativeWork
333 sg:pub.10.1186/1475-2875-6-37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051443131
334 https://doi.org/10.1186/1475-2875-6-37
335 rdf:type schema:CreativeWork
336 sg:pub.10.1186/1475-2875-8-86 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042428786
337 https://doi.org/10.1186/1475-2875-8-86
338 rdf:type schema:CreativeWork
339 sg:pub.10.1385/1-59259-271-6:189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075088149
340 https://doi.org/10.1385/1-59259-271-6:189
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/0166-6851(93)90077-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1046601485
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1016/j.actatropica.2011.02.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048785765
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1016/s0140-6736(12)60484-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053009002
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1016/s0140-6736(89)92800-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003174007
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/s1473-3099(12)70181-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047536348
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1056/nejmc0805011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041561416
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1056/nejmoa0808859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011738279
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1086/644781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010516905
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1128/aac.00686-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036563581
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1128/jcm.02156-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022150656
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1371/journal.pmed.1000400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000364352
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1371/journal.pone.0034040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042850100
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1371/journal.pone.0045797 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015974676
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1371/journal.pone.0057689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001233277
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1586/erm.12.53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039106176
371 rdf:type schema:CreativeWork
372 https://doi.org/10.4269/ajtmh.1999.60.687 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074467440
373 rdf:type schema:CreativeWork
374 https://doi.org/10.4269/ajtmh.2007.77.119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077584378
375 rdf:type schema:CreativeWork
376 https://doi.org/10.4269/ajtmh.2008.78.217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077604289
377 rdf:type schema:CreativeWork
378 https://www.grid.ac/institutes/grid.11505.30 schema:alternateName Institute of Tropical Medicine Antwerp
379 schema:name Institut Pasteur du Cambodge, Phnom Penh, Cambodia
380 Institute of Tropical Medicine, Antwerp, Belgium
381 rdf:type schema:Organization
382 https://www.grid.ac/institutes/grid.418537.c schema:alternateName Institut Pasteur du Cambodge
383 schema:name Institut Pasteur du Cambodge, Phnom Penh, Cambodia
384 rdf:type schema:Organization
385 https://www.grid.ac/institutes/grid.452707.3 schema:alternateName Cambodia National Malaria Center
386 schema:name National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
387 rdf:type schema:Organization
388 https://www.grid.ac/institutes/grid.5284.b schema:alternateName University of Antwerp
389 schema:name Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
390 Institute of Tropical Medicine, Antwerp, Belgium
391 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...