An innovative tool for moving malaria PCR detection of parasite reservoir into the field View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Lydie Canier, Nimol Khim, Saorin Kim, Vincent Sluydts, Somony Heng, Dany Dourng, Rotha Eam, Sophy Chy, Chanra Khean, Kaknika Loch, Malen Ken, Hokkean Lim, Sovannaroath Siv, Sochantha Tho, Pascal Masse-Navette, Charlotte Gryseels, Sambunny Uk, Karel Van Roey, Koen Peeters Grietens, Mao Sokny, Boukheng Thavrin, Char Meng Chuor, Vincent Deubel, Lies Durnez, Marc Coosemans, Didier Ménard

ABSTRACT

BACKGROUND: To achieve the goal of malaria elimination in low transmission areas such as in Cambodia, new, inexpensive, high-throughput diagnostic tools for identifying very low parasite densities in asymptomatic carriers are required. This will enable a switch from passive to active malaria case detection in the field. METHODS: DNA extraction and real-time PCR assays were implemented in an "in-house" designed mobile laboratory allowing implementation of a robust, sensitive and rapid malaria diagnostic strategy in the field. This tool was employed in a survey organized in the context of the MalaResT project (NCT01663831). RESULTS: The real-time PCR screening and species identification assays were performed in the mobile laboratory between October and November 2012, in Rattanakiri Province, to screen approximately 5,000 individuals in less than four weeks and treat parasite carriers within 24-48 hours after sample collection. An average of 240 clinical samples (and 40 quality control samples) was tested every day, six/seven days per week. Some 97.7% of the results were available <24 hours after the collection. A total of 4.9% were positive for malaria. Plasmodium vivax was present in 61.1% of the positive samples, Plasmodium falciparum in 45.9%, Plasmodium malariae in 7.0% and Plasmodium ovale in 2.0%. CONCLUSIONS: The operational success of this diagnostic set-up proved that molecular testing and subsequent treatment is logistically achievable in field settings. This will allow the detection of clusters of asymptomatic carriers and to provide useful epidemiological information. Fast results will be of great help for staff in the field to track and treat asymptomatic parasitaemic cases. The concept of the mobile laboratory could be extended to other countries for the molecular detection of malaria or other pathogens, or to culture vivax parasites, which does not support long-time delay between sample collection and culture. More... »

PAGES

405

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1475-2875-12-405

DOI

http://dx.doi.org/10.1186/1475-2875-12-405

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033011151

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24206649


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Asymptomatic Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cambodia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carrier State", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross-Sectional Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malaria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mass Screening", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Diagnostic Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Epidemiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Parasitology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plasmodium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Real-Time Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Canier", 
        "givenName": "Lydie", 
        "id": "sg:person.01214612750.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214612750.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khim", 
        "givenName": "Nimol", 
        "id": "sg:person.01246467524.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246467524.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Saorin", 
        "id": "sg:person.0667736036.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667736036.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sluydts", 
        "givenName": "Vincent", 
        "id": "sg:person.01175677125.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175677125.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia", 
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heng", 
        "givenName": "Somony", 
        "id": "sg:person.0601773124.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601773124.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dourng", 
        "givenName": "Dany", 
        "id": "sg:person.01372535440.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372535440.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eam", 
        "givenName": "Rotha", 
        "id": "sg:person.01174256532.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174256532.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chy", 
        "givenName": "Sophy", 
        "id": "sg:person.01351070036.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351070036.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khean", 
        "givenName": "Chanra", 
        "id": "sg:person.01310505132.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310505132.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Loch", 
        "givenName": "Kaknika", 
        "id": "sg:person.01356620332.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356620332.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ken", 
        "givenName": "Malen", 
        "id": "sg:person.01022772006.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022772006.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lim", 
        "givenName": "Hokkean", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siv", 
        "givenName": "Sovannaroath", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tho", 
        "givenName": "Sochantha", 
        "id": "sg:person.01015556032.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015556032.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masse-Navette", 
        "givenName": "Pascal", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gryseels", 
        "givenName": "Charlotte", 
        "id": "sg:person.0644245224.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644245224.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uk", 
        "givenName": "Sambunny", 
        "id": "sg:person.0615630713.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615630713.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Roey", 
        "givenName": "Karel", 
        "id": "sg:person.01246233032.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246233032.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grietens", 
        "givenName": "Koen Peeters", 
        "id": "sg:person.01271702207.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271702207.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sokny", 
        "givenName": "Mao", 
        "id": "sg:person.01046601205.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046601205.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thavrin", 
        "givenName": "Boukheng", 
        "id": "sg:person.0637055332.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637055332.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chuor", 
        "givenName": "Char Meng", 
        "id": "sg:person.0736216222.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Deubel", 
        "givenName": "Vincent", 
        "id": "sg:person.0677146672.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677146672.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Tropical Medicine Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.11505.30", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Durnez", 
        "givenName": "Lies", 
        "id": "sg:person.01073106054.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073106054.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.5284.b", 
          "name": [
            "Institute of Tropical Medicine, Antwerp, Belgium", 
            "Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coosemans", 
        "givenName": "Marc", 
        "id": "sg:person.0611227035.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611227035.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Pasteur du Cambodge", 
          "id": "https://www.grid.ac/institutes/grid.418537.c", 
          "name": [
            "Institut Pasteur du Cambodge, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "M\u00e9nard", 
        "givenName": "Didier", 
        "id": "sg:person.0755351436.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755351436.01"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pmed.1000400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000364352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0057689", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001233277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(89)92800-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003174007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-10-323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007247238", 
          "https://doi.org/10.1186/1475-2875-10-323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/644781", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010516905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0808859", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011738279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0045797", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015974676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-12-26", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016660983", 
          "https://doi.org/10.1186/1475-2875-12-26"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.02156-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022150656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028011224", 
          "https://doi.org/10.1186/1475-2875-11-295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028137830", 
          "https://doi.org/10.1186/1475-2875-11-355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.00686-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036563581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1586/erm.12.53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039106176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmc0805011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041561416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-8-86", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042428786", 
          "https://doi.org/10.1186/1475-2875-8-86"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0034040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042850100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0166-6851(93)90077-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046601485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0166-6851(93)90077-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046601485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1473-3099(12)70181-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047536348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.actatropica.2011.02.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048785765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-6-37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051443131", 
          "https://doi.org/10.1186/1475-2875-6-37"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(12)60484-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053009002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.1999.60.687", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074467440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/1-59259-271-6:189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075088149", 
          "https://doi.org/10.1385/1-59259-271-6:189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.2007.77.119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077584378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.2008.78.217", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077604289"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-12", 
    "datePublishedReg": "2013-12-01", 
    "description": "BACKGROUND: To achieve the goal of malaria elimination in low transmission areas such as in Cambodia, new, inexpensive, high-throughput diagnostic tools for identifying very low parasite densities in asymptomatic carriers are required. This will enable a switch from passive to active malaria case detection in the field.\nMETHODS: DNA extraction and real-time PCR assays were implemented in an \"in-house\" designed mobile laboratory allowing implementation of a robust, sensitive and rapid malaria diagnostic strategy in the field. This tool was employed in a survey organized in the context of the MalaResT project (NCT01663831).\nRESULTS: The real-time PCR screening and species identification assays were performed in the mobile laboratory between October and November 2012, in Rattanakiri Province, to screen approximately 5,000 individuals in less than four weeks and treat parasite carriers within 24-48 hours after sample collection. An average of 240 clinical samples (and 40 quality control samples) was tested every day, six/seven days per week. Some 97.7% of the results were available <24 hours after the collection. A total of 4.9% were positive for malaria. Plasmodium vivax was present in 61.1% of the positive samples, Plasmodium falciparum in 45.9%, Plasmodium malariae in 7.0% and Plasmodium ovale in 2.0%.\nCONCLUSIONS: The operational success of this diagnostic set-up proved that molecular testing and subsequent treatment is logistically achievable in field settings. This will allow the detection of clusters of asymptomatic carriers and to provide useful epidemiological information. Fast results will be of great help for staff in the field to track and treat asymptomatic parasitaemic cases. The concept of the mobile laboratory could be extended to other countries for the molecular detection of malaria or other pathogens, or to culture vivax parasites, which does not support long-time delay between sample collection and culture.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1475-2875-12-405", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6585700", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030597", 
        "issn": [
          "1475-2875"
        ], 
        "name": "Malaria Journal", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "12"
      }
    ], 
    "name": "An innovative tool for moving malaria PCR detection of parasite reservoir into the field", 
    "pagination": "405", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9d4280d7c7307a5aa7fa69a0ef61711d74ef9c89c100d1dd4c2a764c76d373f9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24206649"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101139802"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1475-2875-12-405"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033011151"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1475-2875-12-405", 
      "https://app.dimensions.ai/details/publication/pub.1033011151"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000514.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1475-2875-12-405"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1475-2875-12-405'


 

This table displays all metadata directly associated to this object as RDF triples.

391 TRIPLES      21 PREDICATES      68 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1475-2875-12-405 schema:about N0d01539835b04003acc4db0e9407543a
2 N50d7935ab3a9469e9d3c6557b6d3bef4
3 N5dbe9bd455cc4143aafa5bbcb3554306
4 N7373a734ca1c43479d14b8e062aa5352
5 N7f4fc20c07ee4aa9a43ce479718484d1
6 N8bb8b655f54a45f7a2b85aedeac7104b
7 N8c00c7f03c914ced848dc77b5682d93e
8 Nafe22f1abcec43ae8d65b6fbc2ed8e1d
9 Nbf5e8d0aa52a4db3aa77b91e78ab045b
10 Ncf98aadde7ab47c6a30e741c41d10027
11 Nd5b5208187ec413494ca3a235e30ff37
12 Ndcf55cc3f499442aa79054b364846fc6
13 Ndf1ac76554fa4920805edd85e2529940
14 Ned3c76876d564f52a6f68cb1223dba6c
15 anzsrc-for:11
16 anzsrc-for:1108
17 schema:author N7810e2d521a84bf28d4aacf49ce010c8
18 schema:citation sg:pub.10.1186/1475-2875-10-323
19 sg:pub.10.1186/1475-2875-11-295
20 sg:pub.10.1186/1475-2875-11-355
21 sg:pub.10.1186/1475-2875-12-26
22 sg:pub.10.1186/1475-2875-6-37
23 sg:pub.10.1186/1475-2875-8-86
24 sg:pub.10.1385/1-59259-271-6:189
25 https://doi.org/10.1016/0166-6851(93)90077-b
26 https://doi.org/10.1016/j.actatropica.2011.02.016
27 https://doi.org/10.1016/s0140-6736(12)60484-x
28 https://doi.org/10.1016/s0140-6736(89)92800-6
29 https://doi.org/10.1016/s1473-3099(12)70181-0
30 https://doi.org/10.1056/nejmc0805011
31 https://doi.org/10.1056/nejmoa0808859
32 https://doi.org/10.1086/644781
33 https://doi.org/10.1128/aac.00686-12
34 https://doi.org/10.1128/jcm.02156-10
35 https://doi.org/10.1371/journal.pmed.1000400
36 https://doi.org/10.1371/journal.pone.0034040
37 https://doi.org/10.1371/journal.pone.0045797
38 https://doi.org/10.1371/journal.pone.0057689
39 https://doi.org/10.1586/erm.12.53
40 https://doi.org/10.4269/ajtmh.1999.60.687
41 https://doi.org/10.4269/ajtmh.2007.77.119
42 https://doi.org/10.4269/ajtmh.2008.78.217
43 schema:datePublished 2013-12
44 schema:datePublishedReg 2013-12-01
45 schema:description BACKGROUND: To achieve the goal of malaria elimination in low transmission areas such as in Cambodia, new, inexpensive, high-throughput diagnostic tools for identifying very low parasite densities in asymptomatic carriers are required. This will enable a switch from passive to active malaria case detection in the field. METHODS: DNA extraction and real-time PCR assays were implemented in an "in-house" designed mobile laboratory allowing implementation of a robust, sensitive and rapid malaria diagnostic strategy in the field. This tool was employed in a survey organized in the context of the MalaResT project (NCT01663831). RESULTS: The real-time PCR screening and species identification assays were performed in the mobile laboratory between October and November 2012, in Rattanakiri Province, to screen approximately 5,000 individuals in less than four weeks and treat parasite carriers within 24-48 hours after sample collection. An average of 240 clinical samples (and 40 quality control samples) was tested every day, six/seven days per week. Some 97.7% of the results were available <24 hours after the collection. A total of 4.9% were positive for malaria. Plasmodium vivax was present in 61.1% of the positive samples, Plasmodium falciparum in 45.9%, Plasmodium malariae in 7.0% and Plasmodium ovale in 2.0%. CONCLUSIONS: The operational success of this diagnostic set-up proved that molecular testing and subsequent treatment is logistically achievable in field settings. This will allow the detection of clusters of asymptomatic carriers and to provide useful epidemiological information. Fast results will be of great help for staff in the field to track and treat asymptomatic parasitaemic cases. The concept of the mobile laboratory could be extended to other countries for the molecular detection of malaria or other pathogens, or to culture vivax parasites, which does not support long-time delay between sample collection and culture.
46 schema:genre research_article
47 schema:inLanguage en
48 schema:isAccessibleForFree true
49 schema:isPartOf N36b8a90bdc864dc5968297da89e74349
50 N5dd07f619c084b3dbb8b81d178baf2e7
51 sg:journal.1030597
52 schema:name An innovative tool for moving malaria PCR detection of parasite reservoir into the field
53 schema:pagination 405
54 schema:productId N72b82742e4e44f22806898c52385bde7
55 N751213a889564dd9bb914a820322d989
56 N834ddb8ee8ec41a09a6c7c5603514d9d
57 Naf5df2aaadb64a9d8c1c5830d6d65b47
58 Nc021d53bb12242bd895e7c1c6d0f4d86
59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033011151
60 https://doi.org/10.1186/1475-2875-12-405
61 schema:sdDatePublished 2019-04-10T14:10
62 schema:sdLicense https://scigraph.springernature.com/explorer/license/
63 schema:sdPublisher Nffc66d32d9be4c8780c521ddf0f7a954
64 schema:url http://link.springer.com/10.1186%2F1475-2875-12-405
65 sgo:license sg:explorer/license/
66 sgo:sdDataset articles
67 rdf:type schema:ScholarlyArticle
68 N08c538c1411f445bb8d346af7f793919 rdf:first sg:person.01271702207.08
69 rdf:rest N24e35447897648a9af99b3f299aeb595
70 N0c4d339f978a476283393540fd2432c7 rdf:first sg:person.01175677125.45
71 rdf:rest N2670c1a1a1d84272812c688bc8fe3b26
72 N0d01539835b04003acc4db0e9407543a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Carrier State
74 rdf:type schema:DefinedTerm
75 N2142571e09114cf788e802fe86bd3009 rdf:first sg:person.01174256532.34
76 rdf:rest N73fe8f01751c46788ddc12a8c5c963ce
77 N24e35447897648a9af99b3f299aeb595 rdf:first sg:person.01046601205.43
78 rdf:rest N84587e8bb87e40cdb0a8ff41bb1bf21f
79 N2670c1a1a1d84272812c688bc8fe3b26 rdf:first sg:person.0601773124.81
80 rdf:rest Nfd585e68b9ef42a78d6b199c5add220a
81 N279162a03149473ba87ddb57127f73a0 rdf:first sg:person.01356620332.84
82 rdf:rest N7b128d3e62f3451c881e214b49013db0
83 N28734b28f78d4f08b926a7406669b2e9 rdf:first sg:person.0644245224.11
84 rdf:rest N7912e8758af74579a3826e5bf1ef76c1
85 N2e735ddd40444e26bd6997324083375d rdf:first sg:person.0736216222.41
86 rdf:rest N8dfb546ba71c4e23998bc64332c464fe
87 N35d5150833f14d58ad7e9f8d1de44ffc rdf:first sg:person.0611227035.09
88 rdf:rest N93128dc993bf4154a652ca5d4e9a2403
89 N36b8a90bdc864dc5968297da89e74349 schema:volumeNumber 12
90 rdf:type schema:PublicationVolume
91 N3c706b4256e547e0a352eaa5f64abc7b rdf:first sg:person.01310505132.08
92 rdf:rest N279162a03149473ba87ddb57127f73a0
93 N425ce586c03a4d3394066195eb052d80 rdf:first sg:person.01015556032.71
94 rdf:rest N85c7e19cb8c841a8a3b07918859a5da4
95 N50d7935ab3a9469e9d3c6557b6d3bef4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Real-Time Polymerase Chain Reaction
97 rdf:type schema:DefinedTerm
98 N56d961ef397649b4a872c9588fe1b5b3 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
99 schema:familyName Masse-Navette
100 schema:givenName Pascal
101 rdf:type schema:Person
102 N5dbe9bd455cc4143aafa5bbcb3554306 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Humans
104 rdf:type schema:DefinedTerm
105 N5dd07f619c084b3dbb8b81d178baf2e7 schema:issueNumber 1
106 rdf:type schema:PublicationIssue
107 N678f86b4b51c45c89c7af0badead8401 rdf:first Neb504599929540ff9397401a0e00391f
108 rdf:rest Na21422ced8484b25b1fdd34b1e26153c
109 N72b82742e4e44f22806898c52385bde7 schema:name readcube_id
110 schema:value 9d4280d7c7307a5aa7fa69a0ef61711d74ef9c89c100d1dd4c2a764c76d373f9
111 rdf:type schema:PropertyValue
112 N7373a734ca1c43479d14b8e062aa5352 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Sensitivity and Specificity
114 rdf:type schema:DefinedTerm
115 N73fe8f01751c46788ddc12a8c5c963ce rdf:first sg:person.01351070036.77
116 rdf:rest N3c706b4256e547e0a352eaa5f64abc7b
117 N751213a889564dd9bb914a820322d989 schema:name nlm_unique_id
118 schema:value 101139802
119 rdf:type schema:PropertyValue
120 N7810e2d521a84bf28d4aacf49ce010c8 rdf:first sg:person.01214612750.28
121 rdf:rest N9f62f65147be42cf84e6dbc06e286b11
122 N7912e8758af74579a3826e5bf1ef76c1 rdf:first sg:person.0615630713.16
123 rdf:rest Neb77fad831ed4b4fa7b447f05c9f795f
124 N7b128d3e62f3451c881e214b49013db0 rdf:first sg:person.01022772006.34
125 rdf:rest N678f86b4b51c45c89c7af0badead8401
126 N7f4fc20c07ee4aa9a43ce479718484d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Molecular Epidemiology
128 rdf:type schema:DefinedTerm
129 N834ddb8ee8ec41a09a6c7c5603514d9d schema:name doi
130 schema:value 10.1186/1475-2875-12-405
131 rdf:type schema:PropertyValue
132 N84587e8bb87e40cdb0a8ff41bb1bf21f rdf:first sg:person.0637055332.82
133 rdf:rest N2e735ddd40444e26bd6997324083375d
134 N85c7e19cb8c841a8a3b07918859a5da4 rdf:first N56d961ef397649b4a872c9588fe1b5b3
135 rdf:rest N28734b28f78d4f08b926a7406669b2e9
136 N87f0b014ca37464b946dfede3c0cad8c schema:affiliation https://www.grid.ac/institutes/grid.452707.3
137 schema:familyName Siv
138 schema:givenName Sovannaroath
139 rdf:type schema:Person
140 N8bb8b655f54a45f7a2b85aedeac7104b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Time Factors
142 rdf:type schema:DefinedTerm
143 N8c00c7f03c914ced848dc77b5682d93e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Mass Screening
145 rdf:type schema:DefinedTerm
146 N8dfb546ba71c4e23998bc64332c464fe rdf:first sg:person.0677146672.97
147 rdf:rest Ne872659f93614ac486c1f8adb11b3674
148 N912023cda0a5472f841a2a1b25707178 rdf:first sg:person.0667736036.69
149 rdf:rest N0c4d339f978a476283393540fd2432c7
150 N93128dc993bf4154a652ca5d4e9a2403 rdf:first sg:person.0755351436.01
151 rdf:rest rdf:nil
152 N9f62f65147be42cf84e6dbc06e286b11 rdf:first sg:person.01246467524.81
153 rdf:rest N912023cda0a5472f841a2a1b25707178
154 Na21422ced8484b25b1fdd34b1e26153c rdf:first N87f0b014ca37464b946dfede3c0cad8c
155 rdf:rest N425ce586c03a4d3394066195eb052d80
156 Naf5df2aaadb64a9d8c1c5830d6d65b47 schema:name pubmed_id
157 schema:value 24206649
158 rdf:type schema:PropertyValue
159 Nafe22f1abcec43ae8d65b6fbc2ed8e1d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Malaria
161 rdf:type schema:DefinedTerm
162 Nbf5e8d0aa52a4db3aa77b91e78ab045b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Parasitology
164 rdf:type schema:DefinedTerm
165 Nc021d53bb12242bd895e7c1c6d0f4d86 schema:name dimensions_id
166 schema:value pub.1033011151
167 rdf:type schema:PropertyValue
168 Ncf98aadde7ab47c6a30e741c41d10027 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Plasmodium
170 rdf:type schema:DefinedTerm
171 Nd5b5208187ec413494ca3a235e30ff37 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Cross-Sectional Studies
173 rdf:type schema:DefinedTerm
174 Ndcf55cc3f499442aa79054b364846fc6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Molecular Diagnostic Techniques
176 rdf:type schema:DefinedTerm
177 Ndf1ac76554fa4920805edd85e2529940 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Asymptomatic Infections
179 rdf:type schema:DefinedTerm
180 Ne872659f93614ac486c1f8adb11b3674 rdf:first sg:person.01073106054.84
181 rdf:rest N35d5150833f14d58ad7e9f8d1de44ffc
182 Neb504599929540ff9397401a0e00391f schema:affiliation https://www.grid.ac/institutes/grid.418537.c
183 schema:familyName Lim
184 schema:givenName Hokkean
185 rdf:type schema:Person
186 Neb77fad831ed4b4fa7b447f05c9f795f rdf:first sg:person.01246233032.16
187 rdf:rest N08c538c1411f445bb8d346af7f793919
188 Ned3c76876d564f52a6f68cb1223dba6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Cambodia
190 rdf:type schema:DefinedTerm
191 Nfd585e68b9ef42a78d6b199c5add220a rdf:first sg:person.01372535440.56
192 rdf:rest N2142571e09114cf788e802fe86bd3009
193 Nffc66d32d9be4c8780c521ddf0f7a954 schema:name Springer Nature - SN SciGraph project
194 rdf:type schema:Organization
195 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
196 schema:name Medical and Health Sciences
197 rdf:type schema:DefinedTerm
198 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
199 schema:name Medical Microbiology
200 rdf:type schema:DefinedTerm
201 sg:grant.6585700 http://pending.schema.org/fundedItem sg:pub.10.1186/1475-2875-12-405
202 rdf:type schema:MonetaryGrant
203 sg:journal.1030597 schema:issn 1475-2875
204 schema:name Malaria Journal
205 rdf:type schema:Periodical
206 sg:person.01015556032.71 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
207 schema:familyName Tho
208 schema:givenName Sochantha
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015556032.71
210 rdf:type schema:Person
211 sg:person.01022772006.34 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
212 schema:familyName Ken
213 schema:givenName Malen
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022772006.34
215 rdf:type schema:Person
216 sg:person.01046601205.43 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
217 schema:familyName Sokny
218 schema:givenName Mao
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046601205.43
220 rdf:type schema:Person
221 sg:person.01073106054.84 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
222 schema:familyName Durnez
223 schema:givenName Lies
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073106054.84
225 rdf:type schema:Person
226 sg:person.01174256532.34 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
227 schema:familyName Eam
228 schema:givenName Rotha
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174256532.34
230 rdf:type schema:Person
231 sg:person.01175677125.45 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
232 schema:familyName Sluydts
233 schema:givenName Vincent
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175677125.45
235 rdf:type schema:Person
236 sg:person.01214612750.28 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
237 schema:familyName Canier
238 schema:givenName Lydie
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214612750.28
240 rdf:type schema:Person
241 sg:person.01246233032.16 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
242 schema:familyName Van Roey
243 schema:givenName Karel
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246233032.16
245 rdf:type schema:Person
246 sg:person.01246467524.81 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
247 schema:familyName Khim
248 schema:givenName Nimol
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246467524.81
250 rdf:type schema:Person
251 sg:person.01271702207.08 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
252 schema:familyName Grietens
253 schema:givenName Koen Peeters
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271702207.08
255 rdf:type schema:Person
256 sg:person.01310505132.08 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
257 schema:familyName Khean
258 schema:givenName Chanra
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310505132.08
260 rdf:type schema:Person
261 sg:person.01351070036.77 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
262 schema:familyName Chy
263 schema:givenName Sophy
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351070036.77
265 rdf:type schema:Person
266 sg:person.01356620332.84 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
267 schema:familyName Loch
268 schema:givenName Kaknika
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356620332.84
270 rdf:type schema:Person
271 sg:person.01372535440.56 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
272 schema:familyName Dourng
273 schema:givenName Dany
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372535440.56
275 rdf:type schema:Person
276 sg:person.0601773124.81 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
277 schema:familyName Heng
278 schema:givenName Somony
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601773124.81
280 rdf:type schema:Person
281 sg:person.0611227035.09 schema:affiliation https://www.grid.ac/institutes/grid.5284.b
282 schema:familyName Coosemans
283 schema:givenName Marc
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611227035.09
285 rdf:type schema:Person
286 sg:person.0615630713.16 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
287 schema:familyName Uk
288 schema:givenName Sambunny
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615630713.16
290 rdf:type schema:Person
291 sg:person.0637055332.82 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
292 schema:familyName Thavrin
293 schema:givenName Boukheng
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637055332.82
295 rdf:type schema:Person
296 sg:person.0644245224.11 schema:affiliation https://www.grid.ac/institutes/grid.11505.30
297 schema:familyName Gryseels
298 schema:givenName Charlotte
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644245224.11
300 rdf:type schema:Person
301 sg:person.0667736036.69 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
302 schema:familyName Kim
303 schema:givenName Saorin
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667736036.69
305 rdf:type schema:Person
306 sg:person.0677146672.97 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
307 schema:familyName Deubel
308 schema:givenName Vincent
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677146672.97
310 rdf:type schema:Person
311 sg:person.0736216222.41 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
312 schema:familyName Chuor
313 schema:givenName Char Meng
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736216222.41
315 rdf:type schema:Person
316 sg:person.0755351436.01 schema:affiliation https://www.grid.ac/institutes/grid.418537.c
317 schema:familyName Ménard
318 schema:givenName Didier
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755351436.01
320 rdf:type schema:Person
321 sg:pub.10.1186/1475-2875-10-323 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007247238
322 https://doi.org/10.1186/1475-2875-10-323
323 rdf:type schema:CreativeWork
324 sg:pub.10.1186/1475-2875-11-295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028011224
325 https://doi.org/10.1186/1475-2875-11-295
326 rdf:type schema:CreativeWork
327 sg:pub.10.1186/1475-2875-11-355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028137830
328 https://doi.org/10.1186/1475-2875-11-355
329 rdf:type schema:CreativeWork
330 sg:pub.10.1186/1475-2875-12-26 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016660983
331 https://doi.org/10.1186/1475-2875-12-26
332 rdf:type schema:CreativeWork
333 sg:pub.10.1186/1475-2875-6-37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051443131
334 https://doi.org/10.1186/1475-2875-6-37
335 rdf:type schema:CreativeWork
336 sg:pub.10.1186/1475-2875-8-86 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042428786
337 https://doi.org/10.1186/1475-2875-8-86
338 rdf:type schema:CreativeWork
339 sg:pub.10.1385/1-59259-271-6:189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075088149
340 https://doi.org/10.1385/1-59259-271-6:189
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/0166-6851(93)90077-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1046601485
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1016/j.actatropica.2011.02.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048785765
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1016/s0140-6736(12)60484-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053009002
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1016/s0140-6736(89)92800-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003174007
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/s1473-3099(12)70181-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047536348
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1056/nejmc0805011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041561416
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1056/nejmoa0808859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011738279
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1086/644781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010516905
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1128/aac.00686-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036563581
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1128/jcm.02156-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022150656
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1371/journal.pmed.1000400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000364352
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1371/journal.pone.0034040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042850100
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1371/journal.pone.0045797 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015974676
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1371/journal.pone.0057689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001233277
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1586/erm.12.53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039106176
371 rdf:type schema:CreativeWork
372 https://doi.org/10.4269/ajtmh.1999.60.687 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074467440
373 rdf:type schema:CreativeWork
374 https://doi.org/10.4269/ajtmh.2007.77.119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077584378
375 rdf:type schema:CreativeWork
376 https://doi.org/10.4269/ajtmh.2008.78.217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077604289
377 rdf:type schema:CreativeWork
378 https://www.grid.ac/institutes/grid.11505.30 schema:alternateName Institute of Tropical Medicine Antwerp
379 schema:name Institut Pasteur du Cambodge, Phnom Penh, Cambodia
380 Institute of Tropical Medicine, Antwerp, Belgium
381 rdf:type schema:Organization
382 https://www.grid.ac/institutes/grid.418537.c schema:alternateName Institut Pasteur du Cambodge
383 schema:name Institut Pasteur du Cambodge, Phnom Penh, Cambodia
384 rdf:type schema:Organization
385 https://www.grid.ac/institutes/grid.452707.3 schema:alternateName Cambodia National Malaria Center
386 schema:name National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
387 rdf:type schema:Organization
388 https://www.grid.ac/institutes/grid.5284.b schema:alternateName University of Antwerp
389 schema:name Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
390 Institute of Tropical Medicine, Antwerp, Belgium
391 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...