Testicular seminoma – unusual histology and staging with sub epithelial spread of seminoma along the vas deferans View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-12

AUTHORS

Chris J Lockett, Ghulam M Nandwani, Simon R Stubington

ABSTRACT

BACKGROUND: The route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes. CASE PRESENTATION: We present a case report of testicular seminoma in a 56 year old man with previously unreported histological findings. In this case seminoma tumour cells did not appear to have spread by the expected lymphatic route. There was no involvement of retro-peritoneal para-aortic lymph nodes. The tumour appeared to have spread directly along the vas deferans in the sub epithelial plane to the mesenteric lymph nodes. CONCLUSION: This type of seminoma tumour spread has not previously been described and it is not a recognised route for metastasis by seminoma tumour. In this case the macroscopic clinical appearance was of a stage I tumour with normal tumour markers. However, the pathological stage of the tumour was surprisingly increased to stage III on the basis of histology and CT radiological findings. We present the unusual histological findings. In view of this unusual histological finding we reinforce the need for accurate staging and for resection of the spermatic cord close to the deep inguinal ring. Accurate staging is crucial in planning the treatment and follow up of seminoma and determines the prognosis. More... »

PAGES

5

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2490-6-5

DOI

http://dx.doi.org/10.1186/1471-2490-6-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001153415

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16509980


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Epithelium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genital Neoplasms, Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Invasiveness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Seminoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Testicular Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vas Deferens", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Leighton Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415892.3", 
          "name": [
            "Department of Urology, Michael Heal Unit, Leighton Hospital, Middlewich Road, CW1 4QJ, Crewe, Cheshire, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lockett", 
        "givenName": "Chris J", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leighton Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415892.3", 
          "name": [
            "Department of Urology, Michael Heal Unit, Leighton Hospital, Middlewich Road, CW1 4QJ, Crewe, Cheshire, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nandwani", 
        "givenName": "Ghulam M", 
        "id": "sg:person.012465112413.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012465112413.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leighton Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415892.3", 
          "name": [
            "Department of Urology, Michael Heal Unit, Leighton Hospital, Middlewich Road, CW1 4QJ, Crewe, Cheshire, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stubington", 
        "givenName": "Simon R", 
        "id": "sg:person.01115561322.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115561322.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0936-6555(03)00166-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003311660"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0936-6555(03)00166-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003311660"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(01)01456-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037532213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(02)01886-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041534002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(02)01886-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041534002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082180662", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-12", 
    "datePublishedReg": "2006-12-01", 
    "description": "BACKGROUND: The route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes.\nCASE PRESENTATION: We present a case report of testicular seminoma in a 56 year old man with previously unreported histological findings. In this case seminoma tumour cells did not appear to have spread by the expected lymphatic route. There was no involvement of retro-peritoneal para-aortic lymph nodes. The tumour appeared to have spread directly along the vas deferans in the sub epithelial plane to the mesenteric lymph nodes.\nCONCLUSION: This type of seminoma tumour spread has not previously been described and it is not a recognised route for metastasis by seminoma tumour. In this case the macroscopic clinical appearance was of a stage I tumour with normal tumour markers. However, the pathological stage of the tumour was surprisingly increased to stage III on the basis of histology and CT radiological findings. We present the unusual histological findings. In view of this unusual histological finding we reinforce the need for accurate staging and for resection of the spermatic cord close to the deep inguinal ring. Accurate staging is crucial in planning the treatment and follow up of seminoma and determines the prognosis.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2490-6-5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024960", 
        "issn": [
          "1471-2490"
        ], 
        "name": "BMC Urology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Testicular seminoma \u2013 unusual histology and staging with sub epithelial spread of seminoma along the vas deferans", 
    "pagination": "5", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "057ec5cdbb7b0a929f0e244946906f91628d3dece2e153c3cd247de27a8375a9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16509980"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968571"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2490-6-5"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1001153415"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2490-6-5", 
      "https://app.dimensions.ai/details/publication/pub.1001153415"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:37", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000549.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2490-6-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2490-6-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2490-6-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2490-6-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2490-6-5'


 

This table displays all metadata directly associated to this object as RDF triples.

132 TRIPLES      21 PREDICATES      43 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2490-6-5 schema:about N034d682593714795879f2deedae57891
2 N0583bf637f9e4d4abab7ab86df162df6
3 N6597debeea3a47e0866a4ee87e40efcb
4 N8bf792e94e1b4715b25a75ea98a4a430
5 N8e772646f76a4cdf85d3d3f653a03381
6 N9b931f57cd8d423e8a792a468df760a7
7 Na495bbc9a0824fef852ccff3b2c0d721
8 Nb4ed7ae7fdce4eb4befae2d6e527866e
9 Ne6e2b9f9aa0d44b484921e95063fa9ed
10 Nf10e3d78608b458dae55f194a7f26f4b
11 anzsrc-for:11
12 anzsrc-for:1112
13 schema:author Neb0343b9f4094a0e881116bb21fa0952
14 schema:citation https://app.dimensions.ai/details/publication/pub.1082180662
15 https://doi.org/10.1016/s0090-4295(01)01456-x
16 https://doi.org/10.1016/s0090-4295(02)01886-1
17 https://doi.org/10.1016/s0936-6555(03)00166-3
18 schema:datePublished 2006-12
19 schema:datePublishedReg 2006-12-01
20 schema:description BACKGROUND: The route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes. CASE PRESENTATION: We present a case report of testicular seminoma in a 56 year old man with previously unreported histological findings. In this case seminoma tumour cells did not appear to have spread by the expected lymphatic route. There was no involvement of retro-peritoneal para-aortic lymph nodes. The tumour appeared to have spread directly along the vas deferans in the sub epithelial plane to the mesenteric lymph nodes. CONCLUSION: This type of seminoma tumour spread has not previously been described and it is not a recognised route for metastasis by seminoma tumour. In this case the macroscopic clinical appearance was of a stage I tumour with normal tumour markers. However, the pathological stage of the tumour was surprisingly increased to stage III on the basis of histology and CT radiological findings. We present the unusual histological findings. In view of this unusual histological finding we reinforce the need for accurate staging and for resection of the spermatic cord close to the deep inguinal ring. Accurate staging is crucial in planning the treatment and follow up of seminoma and determines the prognosis.
21 schema:genre research_article
22 schema:inLanguage en
23 schema:isAccessibleForFree true
24 schema:isPartOf N842e852e7c364b40b898f09880e0743f
25 Nedb3db8ed9794bc0b2f3aaa0f7e12e51
26 sg:journal.1024960
27 schema:name Testicular seminoma – unusual histology and staging with sub epithelial spread of seminoma along the vas deferans
28 schema:pagination 5
29 schema:productId N3f1c7485807b41848bf47a2d628026c8
30 N5b09a2a65ca944668ec9bf9be95cfa09
31 Nc3e7ad4d092c40f4871cea2049e331a9
32 Nc921e52314ac42e4acdbacaa33a4d4bf
33 Nd7d0715466344eb8823a1c85b72cc2ee
34 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001153415
35 https://doi.org/10.1186/1471-2490-6-5
36 schema:sdDatePublished 2019-04-10T17:37
37 schema:sdLicense https://scigraph.springernature.com/explorer/license/
38 schema:sdPublisher N999ef935f30a4820bce9ac0391816159
39 schema:url http://link.springer.com/10.1186%2F1471-2490-6-5
40 sgo:license sg:explorer/license/
41 sgo:sdDataset articles
42 rdf:type schema:ScholarlyArticle
43 N034d682593714795879f2deedae57891 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
44 schema:name Middle Aged
45 rdf:type schema:DefinedTerm
46 N0583bf637f9e4d4abab7ab86df162df6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
47 schema:name Epithelium
48 rdf:type schema:DefinedTerm
49 N3aa3501e4b7141e193b9d50f332efc0b rdf:first sg:person.012465112413.95
50 rdf:rest N76745e6304ae4ba88cbe85f0de1d2a43
51 N3f1c7485807b41848bf47a2d628026c8 schema:name nlm_unique_id
52 schema:value 100968571
53 rdf:type schema:PropertyValue
54 N5b09a2a65ca944668ec9bf9be95cfa09 schema:name readcube_id
55 schema:value 057ec5cdbb7b0a929f0e244946906f91628d3dece2e153c3cd247de27a8375a9
56 rdf:type schema:PropertyValue
57 N6597debeea3a47e0866a4ee87e40efcb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
58 schema:name Humans
59 rdf:type schema:DefinedTerm
60 N76745e6304ae4ba88cbe85f0de1d2a43 rdf:first sg:person.01115561322.39
61 rdf:rest rdf:nil
62 N842e852e7c364b40b898f09880e0743f schema:volumeNumber 6
63 rdf:type schema:PublicationVolume
64 N8bf792e94e1b4715b25a75ea98a4a430 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Testicular Neoplasms
66 rdf:type schema:DefinedTerm
67 N8e772646f76a4cdf85d3d3f653a03381 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Genital Neoplasms, Male
69 rdf:type schema:DefinedTerm
70 N999ef935f30a4820bce9ac0391816159 schema:name Springer Nature - SN SciGraph project
71 rdf:type schema:Organization
72 N9b931f57cd8d423e8a792a468df760a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Male
74 rdf:type schema:DefinedTerm
75 Na495bbc9a0824fef852ccff3b2c0d721 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Vas Deferens
77 rdf:type schema:DefinedTerm
78 Nb4ed7ae7fdce4eb4befae2d6e527866e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Neoplasm Staging
80 rdf:type schema:DefinedTerm
81 Nc3e7ad4d092c40f4871cea2049e331a9 schema:name dimensions_id
82 schema:value pub.1001153415
83 rdf:type schema:PropertyValue
84 Nc921e52314ac42e4acdbacaa33a4d4bf schema:name doi
85 schema:value 10.1186/1471-2490-6-5
86 rdf:type schema:PropertyValue
87 Ncaeb72a447384740a77a2cd12e62e330 schema:affiliation https://www.grid.ac/institutes/grid.415892.3
88 schema:familyName Lockett
89 schema:givenName Chris J
90 rdf:type schema:Person
91 Nd7d0715466344eb8823a1c85b72cc2ee schema:name pubmed_id
92 schema:value 16509980
93 rdf:type schema:PropertyValue
94 Ne6e2b9f9aa0d44b484921e95063fa9ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Neoplasm Invasiveness
96 rdf:type schema:DefinedTerm
97 Neb0343b9f4094a0e881116bb21fa0952 rdf:first Ncaeb72a447384740a77a2cd12e62e330
98 rdf:rest N3aa3501e4b7141e193b9d50f332efc0b
99 Nedb3db8ed9794bc0b2f3aaa0f7e12e51 schema:issueNumber 1
100 rdf:type schema:PublicationIssue
101 Nf10e3d78608b458dae55f194a7f26f4b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Seminoma
103 rdf:type schema:DefinedTerm
104 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
105 schema:name Medical and Health Sciences
106 rdf:type schema:DefinedTerm
107 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
108 schema:name Oncology and Carcinogenesis
109 rdf:type schema:DefinedTerm
110 sg:journal.1024960 schema:issn 1471-2490
111 schema:name BMC Urology
112 rdf:type schema:Periodical
113 sg:person.01115561322.39 schema:affiliation https://www.grid.ac/institutes/grid.415892.3
114 schema:familyName Stubington
115 schema:givenName Simon R
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115561322.39
117 rdf:type schema:Person
118 sg:person.012465112413.95 schema:affiliation https://www.grid.ac/institutes/grid.415892.3
119 schema:familyName Nandwani
120 schema:givenName Ghulam M
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012465112413.95
122 rdf:type schema:Person
123 https://app.dimensions.ai/details/publication/pub.1082180662 schema:CreativeWork
124 https://doi.org/10.1016/s0090-4295(01)01456-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037532213
125 rdf:type schema:CreativeWork
126 https://doi.org/10.1016/s0090-4295(02)01886-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041534002
127 rdf:type schema:CreativeWork
128 https://doi.org/10.1016/s0936-6555(03)00166-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003311660
129 rdf:type schema:CreativeWork
130 https://www.grid.ac/institutes/grid.415892.3 schema:alternateName Leighton Hospital
131 schema:name Department of Urology, Michael Heal Unit, Leighton Hospital, Middlewich Road, CW1 4QJ, Crewe, Cheshire, UK
132 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...