Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-12

AUTHORS

Marc GH Besselink, Hjalmar C van Santvoort, Vincent B Nieuwenhuijs, Marja A Boermeester, Thomas L Bollen, Erik Buskens, Cornelis HC Dejong, Casper HJ van Eijck, Harry van Goor, Sijbrand S Hofker, Johan S Lameris, Maarten S van Leeuwen, Rutger J Ploeg, Bert van Ramshorst, Alexander FM Schaapherder, Miguel A Cuesta, Esther CJ Consten, Dirk J Gouma, Erwin van der Harst, Eric J Hesselink, Lex PJ Houdijk, Tom M Karsten, Cees JHM van Laarhoven, Jean-Pierre EN Pierie, Camiel Rosman, Ernst Jan Spillenaar Bilgen, Robin Timmer, Ingeborg van der Tweel, Ralph J de Wit, Ben JM Witteman, Hein G Gooszen, members of the Dutch Acute Pancreatitis Study Group

ABSTRACT

BACKGROUND: The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision. METHODS/DESIGN: 88 patients with (suspected) infected necrotizing pancreatitis will be randomly allocated to either group A) minimally invasive 'step-up approach' starting with drainage followed, if necessary, by videoscopic assisted retroperitoneal debridement (VARD) or group B) maximal necrosectomy by laparotomy. Both procedures are followed by CPL. Patients will be recruited from 20 hospitals, including all Dutch university medical centres, over a 3-year period. The primary endpoint is the proportion of patients suffering from postoperative major morbidity and mortality. Secondary endpoints are complications, new onset sepsis, length of hospital and intensive care stay, quality of life and total (direct and indirect) costs. To demonstrate that the 'step-up approach' can reduce the major morbidity and mortality rate from 45 to 16%, with 80% power at 5% alpha, a total sample size of 88 patients was calculated. DISCUSSION: The PANTER-study is a randomised controlled trial that will provide evidence on the merits of a minimally invasive 'step-up approach' in patients with (suspected) infected necrotizing pancreatitis. More... »

PAGES

6

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2482-6-6

DOI

http://dx.doi.org/10.1186/1471-2482-6-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010301029

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16606471


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drainage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Laparotomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pancreatitis, Acute Necrotizing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postoperative Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Therapeutic Irrigation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Video-Assisted Surgery", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Surgery, University Medical Center Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Besselink", 
        "givenName": "Marc GH", 
        "id": "sg:person.01120602634.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120602634.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Surgery, University Medical Center Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Santvoort", 
        "givenName": "Hjalmar C", 
        "id": "sg:person.01004354234.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004354234.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Surgery, University Medical Center Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nieuwenhuijs", 
        "givenName": "Vincent B", 
        "id": "sg:person.01260467012.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260467012.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.5650.6", 
          "name": [
            "Department of Surgery, Academic Medical Center Amsterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boermeester", 
        "givenName": "Marja A", 
        "id": "sg:person.0647017707.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647017707.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. Antonius Ziekenhuis", 
          "id": "https://www.grid.ac/institutes/grid.415960.f", 
          "name": [
            "Department of Radiology, St. Antonius Hospital Nieuwegein, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bollen", 
        "givenName": "Thomas L", 
        "id": "sg:person.01245702365.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245702365.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Buskens", 
        "givenName": "Erik", 
        "id": "sg:person.0661463615.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661463615.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, University Hospital Maastricht and NUTRIM institute, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dejong", 
        "givenName": "Cornelis HC", 
        "id": "sg:person.016643776077.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016643776077.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Erasmus University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.5645.2", 
          "name": [
            "Department of Surgery, Erasmus Medical Center Rotterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Eijck", 
        "givenName": "Casper HJ", 
        "id": "sg:person.015263522637.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015263522637.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Radboud University Nijmegen Medical Centre", 
          "id": "https://www.grid.ac/institutes/grid.10417.33", 
          "name": [
            "Department of Surgery, Radboud University Nijmegen Medical Centre, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Goor", 
        "givenName": "Harry", 
        "id": "sg:person.0622270010.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622270010.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Groningen", 
          "id": "https://www.grid.ac/institutes/grid.4494.d", 
          "name": [
            "Department of Surgery, University Medical Center Groningen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hofker", 
        "givenName": "Sijbrand S", 
        "id": "sg:person.01145111140.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145111140.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.5650.6", 
          "name": [
            "Department of Radiology, Academic Medical Center Amsterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lameris", 
        "givenName": "Johan S", 
        "id": "sg:person.01365653063.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365653063.24"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "van Leeuwen", 
        "givenName": "Maarten S", 
        "id": "sg:person.0667406735.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667406735.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Groningen", 
          "id": "https://www.grid.ac/institutes/grid.4494.d", 
          "name": [
            "Department of Surgery, University Medical Center Groningen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ploeg", 
        "givenName": "Rutger J", 
        "id": "sg:person.01007165675.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007165675.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. Antonius Ziekenhuis", 
          "id": "https://www.grid.ac/institutes/grid.415960.f", 
          "name": [
            "Department of Surgery, St. Antonius Hospital Nieuwegein, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Ramshorst", 
        "givenName": "Bert", 
        "id": "sg:person.0756446730.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756446730.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leiden University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.10419.3d", 
          "name": [
            "Department of Surgery, Leiden University Medical Center, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schaapherder", 
        "givenName": "Alexander FM", 
        "id": "sg:person.014611400467.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014611400467.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "VU University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.16872.3a", 
          "name": [
            "Department of Surgery, VU Medical Center Amsterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cuesta", 
        "givenName": "Miguel A", 
        "id": "sg:person.011106774542.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011106774542.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Meander Medical Center Amersfoort, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Consten", 
        "givenName": "Esther CJ", 
        "id": "sg:person.012356347224.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012356347224.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.5650.6", 
          "name": [
            "Department of Surgery, Academic Medical Center Amsterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gouma", 
        "givenName": "Dirk J", 
        "id": "sg:person.0650623704.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650623704.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Medical Center Rijnmond Zuid Rotterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van der Harst", 
        "givenName": "Erwin", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Gelre Hospitals Apeldoorn, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hesselink", 
        "givenName": "Eric J", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medisch Centrum Alkmaar", 
          "id": "https://www.grid.ac/institutes/grid.414828.3", 
          "name": [
            "Department of Surgery, Medical Center Alkmaar, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Houdijk", 
        "givenName": "Lex PJ", 
        "id": "sg:person.0710630520.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710630520.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Reinier de Graaf Group Delft, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karsten", 
        "givenName": "Tom M", 
        "id": "sg:person.01000101007.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000101007.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, St. Elisabeth Hospital Tilburg, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Laarhoven", 
        "givenName": "Cees JHM", 
        "id": "sg:person.011213207434.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011213207434.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medisch Centrum Leeuwarden", 
          "id": "https://www.grid.ac/institutes/grid.414846.b", 
          "name": [
            "Department of Surgery, Medical Center Leeuwarden, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pierie", 
        "givenName": "Jean-Pierre EN", 
        "id": "sg:person.010055554454.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010055554454.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Canisius Wilhelmina Hospital Nijmegen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rosman", 
        "givenName": "Camiel", 
        "id": "sg:person.01075131625.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075131625.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rijnstate Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415930.a", 
          "name": [
            "Department of Surgery, Rijnstate Hospital Arnhem, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bilgen", 
        "givenName": "Ernst Jan Spillenaar", 
        "id": "sg:person.0717210535.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717210535.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. Antonius Ziekenhuis", 
          "id": "https://www.grid.ac/institutes/grid.415960.f", 
          "name": [
            "Department of Gastroenterology, St. Antonius Hospital Nieuwegein, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Timmer", 
        "givenName": "Robin", 
        "id": "sg:person.01362130765.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362130765.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Utrecht University", 
          "id": "https://www.grid.ac/institutes/grid.5477.1", 
          "name": [
            "Utrecht University, Centre for Biostatistics, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van der Tweel", 
        "givenName": "Ingeborg", 
        "id": "sg:person.01315475001.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315475001.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medisch Spectrum Twente", 
          "id": "https://www.grid.ac/institutes/grid.415214.7", 
          "name": [
            "Department of Surgery, Medical Spectrum Twente, Enschede, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Wit", 
        "givenName": "Ralph J", 
        "id": "sg:person.01317757465.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317757465.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Gastroenterology and Hepatology, Gelderse Vallei Ede, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Witteman", 
        "givenName": "Ben JM", 
        "id": "sg:person.015435713307.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015435713307.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Surgery, University Medical Center Utrecht, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gooszen", 
        "givenName": "Hein G", 
        "id": "sg:person.0673766734.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673766734.92"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "members of the Dutch Acute Pancreatitis Study Group", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/01.sla.0000188462.00249.36", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004179108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000188462.00249.36", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004179108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000188462.00249.36", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004179108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800750306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006375562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2004.057026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010523554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1051-0443(98)70323-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013259893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0016-5107(05)00541-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015525012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.1993.01420170122019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015767287"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000071184", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016959571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2482-4-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017799402", 
          "https://doi.org/10.1186/1471-2482-4-12"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(96)00425-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020261833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1440-1746.17.s1.2.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021754604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0001-4001(99)80039-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024736417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004640080166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029907401", 
          "https://doi.org/10.1007/s004640080166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.38118.593900.55", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031677825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2003.035907", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043577916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.5287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047282225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.5287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047282225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/gast.1996.v111.pm8780582", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050513438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000071269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052011841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000071269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052011841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-200008000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052624714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-200008000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052624714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/00855920310002799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058289175"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-199811000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060173147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-199811000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060173147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-199811000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060173147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.170.4.9530046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069321544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.170.4.9530047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069321545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077026500", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-12", 
    "datePublishedReg": "2006-12-01", 
    "description": "BACKGROUND: The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision.\nMETHODS/DESIGN: 88 patients with (suspected) infected necrotizing pancreatitis will be randomly allocated to either group A) minimally invasive 'step-up approach' starting with drainage followed, if necessary, by videoscopic assisted retroperitoneal debridement (VARD) or group B) maximal necrosectomy by laparotomy. Both procedures are followed by CPL. Patients will be recruited from 20 hospitals, including all Dutch university medical centres, over a 3-year period. The primary endpoint is the proportion of patients suffering from postoperative major morbidity and mortality. Secondary endpoints are complications, new onset sepsis, length of hospital and intensive care stay, quality of life and total (direct and indirect) costs. To demonstrate that the 'step-up approach' can reduce the major morbidity and mortality rate from 45 to 16%, with 80% power at 5% alpha, a total sample size of 88 patients was calculated.\nDISCUSSION: The PANTER-study is a randomised controlled trial that will provide evidence on the merits of a minimally invasive 'step-up approach' in patients with (suspected) infected necrotizing pancreatitis.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2482-6-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024958", 
        "issn": [
          "1471-2482"
        ], 
        "name": "BMC Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN13975868]", 
    "pagination": "6", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "31134efe4932f785bc75e7d745bddbde10efa6986f4c6e58b03dc2ea3d98e3d9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16606471"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968567"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2482-6-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1010301029"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2482-6-6", 
      "https://app.dimensions.ai/details/publication/pub.1010301029"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000510.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2482-6-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2482-6-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2482-6-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2482-6-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2482-6-6'


 

This table displays all metadata directly associated to this object as RDF triples.

437 TRIPLES      21 PREDICATES      60 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2482-6-6 schema:about N5633aa09fe3d4ea9ada6cc6e7debea7f
2 Na2c931d4c44941c6a2f0967f296b63d8
3 Nb440874ce0444a269de5ba7882b0d028
4 Nb7ea5701c54b48ceb20cf55a0a7eec27
5 Nbd7339d7d8424f7aa406717d16f7983d
6 Nc063f58b0a82499e853ac65586c01621
7 Ne1f5bf8ae1b948f98739c25aee20b24e
8 anzsrc-for:11
9 anzsrc-for:1103
10 schema:author N89a821d8cbae432fb68aaa4c9c28859c
11 schema:citation sg:pub.10.1007/bf01709751
12 sg:pub.10.1007/s004640080166
13 sg:pub.10.1186/1471-2482-4-12
14 https://app.dimensions.ai/details/publication/pub.1077026500
15 https://doi.org/10.1001/archsurg.1993.01420170122019
16 https://doi.org/10.1002/bjs.1800750306
17 https://doi.org/10.1002/bjs.5287
18 https://doi.org/10.1016/s0001-4001(99)80039-7
19 https://doi.org/10.1016/s0002-9610(96)00425-4
20 https://doi.org/10.1016/s0016-5107(05)00541-9
21 https://doi.org/10.1016/s1051-0443(98)70323-9
22 https://doi.org/10.1046/j.1440-1746.17.s1.2.x
23 https://doi.org/10.1053/gast.1996.v111.pm8780582
24 https://doi.org/10.1080/00855920310002799
25 https://doi.org/10.1097/00000658-200008000-00004
26 https://doi.org/10.1097/00003246-199811000-00016
27 https://doi.org/10.1097/01.sla.0000188462.00249.36
28 https://doi.org/10.1136/bmj.38118.593900.55
29 https://doi.org/10.1136/gut.2003.035907
30 https://doi.org/10.1136/gut.2004.057026
31 https://doi.org/10.1159/000071184
32 https://doi.org/10.1159/000071269
33 https://doi.org/10.2214/ajr.170.4.9530046
34 https://doi.org/10.2214/ajr.170.4.9530047
35 schema:datePublished 2006-12
36 schema:datePublishedReg 2006-12-01
37 schema:description BACKGROUND: The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision. METHODS/DESIGN: 88 patients with (suspected) infected necrotizing pancreatitis will be randomly allocated to either group A) minimally invasive 'step-up approach' starting with drainage followed, if necessary, by videoscopic assisted retroperitoneal debridement (VARD) or group B) maximal necrosectomy by laparotomy. Both procedures are followed by CPL. Patients will be recruited from 20 hospitals, including all Dutch university medical centres, over a 3-year period. The primary endpoint is the proportion of patients suffering from postoperative major morbidity and mortality. Secondary endpoints are complications, new onset sepsis, length of hospital and intensive care stay, quality of life and total (direct and indirect) costs. To demonstrate that the 'step-up approach' can reduce the major morbidity and mortality rate from 45 to 16%, with 80% power at 5% alpha, a total sample size of 88 patients was calculated. DISCUSSION: The PANTER-study is a randomised controlled trial that will provide evidence on the merits of a minimally invasive 'step-up approach' in patients with (suspected) infected necrotizing pancreatitis.
38 schema:genre research_article
39 schema:inLanguage en
40 schema:isAccessibleForFree true
41 schema:isPartOf N7449bff8e09a4683987ff68992c078c3
42 N99216fa5c5924c53ad4e70c223965314
43 sg:journal.1024958
44 schema:name Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN13975868]
45 schema:pagination 6
46 schema:productId N2b458e8f3c534ed9baedc98ae5ca2344
47 N51f66ce5a02f42f7bbf1b74d8c658e84
48 N6f9c84a3ae2142da9b51b12d4bd0f0f1
49 Nc38fa536b423468ca8b76f6ca356420d
50 Nfab2c0cc4bec4e64930468744c176c93
51 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010301029
52 https://doi.org/10.1186/1471-2482-6-6
53 schema:sdDatePublished 2019-04-11T01:59
54 schema:sdLicense https://scigraph.springernature.com/explorer/license/
55 schema:sdPublisher N1775d452fbb847d3bcd2e693b7e96e44
56 schema:url http://link.springer.com/10.1186%2F1471-2482-6-6
57 sgo:license sg:explorer/license/
58 sgo:sdDataset articles
59 rdf:type schema:ScholarlyArticle
60 N0b8c5870944542e5af68573f8ae8e09b rdf:first sg:person.01260467012.10
61 rdf:rest Nffdfcce670264e9e8cd899a385b838cc
62 N12a0ce2dde1648428c7cf2ce8d9a2eda rdf:first sg:person.01362130765.43
63 rdf:rest N8909e03c717e44238218e0ccf52e534d
64 N1775d452fbb847d3bcd2e693b7e96e44 schema:name Springer Nature - SN SciGraph project
65 rdf:type schema:Organization
66 N1c5c3cfebcc24a348a4769e30cf8a20e rdf:first sg:person.0756446730.73
67 rdf:rest Nfc9b980295714b00926ee8b8311a86f4
68 N2770976d620c4be5a01b75b7377c69a0 rdf:first sg:person.012356347224.02
69 rdf:rest Nb32a5dfa8a6849299b92a9704319e3d3
70 N2a47e6ea7519409082fea9c383ad3d74 rdf:first sg:person.01004354234.80
71 rdf:rest N0b8c5870944542e5af68573f8ae8e09b
72 N2b458e8f3c534ed9baedc98ae5ca2344 schema:name readcube_id
73 schema:value 31134efe4932f785bc75e7d745bddbde10efa6986f4c6e58b03dc2ea3d98e3d9
74 rdf:type schema:PropertyValue
75 N2cbda9ce973f42ba9686237b9a40ffae schema:name Department of Surgery, St. Elisabeth Hospital Tilburg, The Netherlands
76 rdf:type schema:Organization
77 N41081bbaf1f048228cec62b32737911e schema:name Department of Gastroenterology and Hepatology, Gelderse Vallei Ede, The Netherlands
78 rdf:type schema:Organization
79 N434a494870544fb4985394b3abfc53f6 rdf:first Nf2ca197519ee40b38a50401ca7a8306c
80 rdf:rest Nd43bc90233884473b70ec9209c317c0c
81 N4564f47c83b24c999c4aefcd6cc18dcb rdf:first sg:person.01365653063.24
82 rdf:rest Nd39f3d05896447c993896030bb28bb30
83 N459ece9d89f34cbf914c3d3285d383af schema:affiliation N7d19880f9a1448cda6f21458e8c42c55
84 schema:familyName Hesselink
85 schema:givenName Eric J
86 rdf:type schema:Person
87 N4d29a97ff0194be2aabbdede686b4a34 rdf:first sg:person.0673766734.92
88 rdf:rest N579097267b3448c5a2a7b95906ac37f4
89 N51f66ce5a02f42f7bbf1b74d8c658e84 schema:name pubmed_id
90 schema:value 16606471
91 rdf:type schema:PropertyValue
92 N56209a0a5279470288b54ef1737737c4 rdf:first sg:person.01317757465.19
93 rdf:rest Nf39a8e2f990d406c87de173a7f187d17
94 N5633aa09fe3d4ea9ada6cc6e7debea7f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Laparotomy
96 rdf:type schema:DefinedTerm
97 N579097267b3448c5a2a7b95906ac37f4 rdf:first N8f95863a94ac474690c7c3078e8676b6
98 rdf:rest rdf:nil
99 N5938dde9a9674b1facdf9a5c3cb39a09 rdf:first sg:person.010055554454.90
100 rdf:rest N9a742c7c3bdd443fb48bfb880ad645ac
101 N60de2034a8a5426684910d2134fa2dc7 rdf:first sg:person.0710630520.06
102 rdf:rest Nf6c648e533fb4c31a6ce1ca168d53065
103 N642f5ba828074575b7e0ac0e9c3d5bdd schema:name Department of Surgery, University Hospital Maastricht and NUTRIM institute, The Netherlands
104 rdf:type schema:Organization
105 N6c2087c2f80b4e80918b668a886b5fcf rdf:first sg:person.01007165675.69
106 rdf:rest N1c5c3cfebcc24a348a4769e30cf8a20e
107 N6f9c84a3ae2142da9b51b12d4bd0f0f1 schema:name dimensions_id
108 schema:value pub.1010301029
109 rdf:type schema:PropertyValue
110 N7449bff8e09a4683987ff68992c078c3 schema:issueNumber 1
111 rdf:type schema:PublicationIssue
112 N7d19880f9a1448cda6f21458e8c42c55 schema:name Department of Surgery, Gelre Hospitals Apeldoorn, The Netherlands
113 rdf:type schema:Organization
114 N8909e03c717e44238218e0ccf52e534d rdf:first sg:person.01315475001.85
115 rdf:rest N56209a0a5279470288b54ef1737737c4
116 N89a821d8cbae432fb68aaa4c9c28859c rdf:first sg:person.01120602634.21
117 rdf:rest N2a47e6ea7519409082fea9c383ad3d74
118 N8f95863a94ac474690c7c3078e8676b6 schema:familyName members of the Dutch Acute Pancreatitis Study Group
119 rdf:type schema:Person
120 N92d2becfe85b48d9ba8f26b68ab00eb9 rdf:first sg:person.015263522637.41
121 rdf:rest Na826e24ac91e4559b1b91ae370191015
122 N937e0fa752f742a0830cd8fe6084a723 rdf:first sg:person.0661463615.08
123 rdf:rest Nb22282ef31be4a6692cb4727c5919fa3
124 N984d008190c044c1a7f21ababad79dd7 schema:name Department of Surgery, Reinier de Graaf Group Delft, The Netherlands
125 rdf:type schema:Organization
126 N99216fa5c5924c53ad4e70c223965314 schema:volumeNumber 6
127 rdf:type schema:PublicationVolume
128 N9a742c7c3bdd443fb48bfb880ad645ac rdf:first sg:person.01075131625.29
129 rdf:rest Ndf4359d464554c4cab524e9c7f594a64
130 Na0c24976c27243138fd973e0412c9ae3 rdf:first sg:person.011213207434.61
131 rdf:rest N5938dde9a9674b1facdf9a5c3cb39a09
132 Na2c931d4c44941c6a2f0967f296b63d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Humans
134 rdf:type schema:DefinedTerm
135 Na826e24ac91e4559b1b91ae370191015 rdf:first sg:person.0622270010.09
136 rdf:rest Nbd6c82a3af194963a8c81b60acad3ade
137 Nb22282ef31be4a6692cb4727c5919fa3 rdf:first sg:person.016643776077.99
138 rdf:rest N92d2becfe85b48d9ba8f26b68ab00eb9
139 Nb32a5dfa8a6849299b92a9704319e3d3 rdf:first sg:person.0650623704.27
140 rdf:rest N434a494870544fb4985394b3abfc53f6
141 Nb440874ce0444a269de5ba7882b0d028 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Drainage
143 rdf:type schema:DefinedTerm
144 Nb7ea5701c54b48ceb20cf55a0a7eec27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Postoperative Care
146 rdf:type schema:DefinedTerm
147 Nbd6c82a3af194963a8c81b60acad3ade rdf:first sg:person.01145111140.65
148 rdf:rest N4564f47c83b24c999c4aefcd6cc18dcb
149 Nbd7339d7d8424f7aa406717d16f7983d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Therapeutic Irrigation
151 rdf:type schema:DefinedTerm
152 Nc063f58b0a82499e853ac65586c01621 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Pancreatitis, Acute Necrotizing
154 rdf:type schema:DefinedTerm
155 Nc38fa536b423468ca8b76f6ca356420d schema:name doi
156 schema:value 10.1186/1471-2482-6-6
157 rdf:type schema:PropertyValue
158 Nc4c79b71226f4fe6990d74eddf664142 schema:name Department of Surgery, Meander Medical Center Amersfoort, The Netherlands
159 rdf:type schema:Organization
160 Nd044f49562714fde9c12cf0ca4239b12 schema:name Department of Surgery, Medical Center Rijnmond Zuid Rotterdam, The Netherlands
161 rdf:type schema:Organization
162 Nd39f3d05896447c993896030bb28bb30 rdf:first sg:person.0667406735.21
163 rdf:rest N6c2087c2f80b4e80918b668a886b5fcf
164 Nd43bc90233884473b70ec9209c317c0c rdf:first N459ece9d89f34cbf914c3d3285d383af
165 rdf:rest N60de2034a8a5426684910d2134fa2dc7
166 Nda4679700f3a4ccd96c8192344e29ec6 rdf:first sg:person.011106774542.16
167 rdf:rest N2770976d620c4be5a01b75b7377c69a0
168 Ndf4359d464554c4cab524e9c7f594a64 rdf:first sg:person.0717210535.99
169 rdf:rest N12a0ce2dde1648428c7cf2ce8d9a2eda
170 Ne1f5bf8ae1b948f98739c25aee20b24e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Video-Assisted Surgery
172 rdf:type schema:DefinedTerm
173 Ne9888658a0e645189ecc3f2d3d6fd85c rdf:first sg:person.01245702365.66
174 rdf:rest N937e0fa752f742a0830cd8fe6084a723
175 Nf1919e7fe8904a30ac239e26f1854f99 schema:name Department of Surgery, Canisius Wilhelmina Hospital Nijmegen, The Netherlands
176 rdf:type schema:Organization
177 Nf2ca197519ee40b38a50401ca7a8306c schema:affiliation Nd044f49562714fde9c12cf0ca4239b12
178 schema:familyName van der Harst
179 schema:givenName Erwin
180 rdf:type schema:Person
181 Nf39a8e2f990d406c87de173a7f187d17 rdf:first sg:person.015435713307.43
182 rdf:rest N4d29a97ff0194be2aabbdede686b4a34
183 Nf6c648e533fb4c31a6ce1ca168d53065 rdf:first sg:person.01000101007.88
184 rdf:rest Na0c24976c27243138fd973e0412c9ae3
185 Nfab2c0cc4bec4e64930468744c176c93 schema:name nlm_unique_id
186 schema:value 100968567
187 rdf:type schema:PropertyValue
188 Nfc9b980295714b00926ee8b8311a86f4 rdf:first sg:person.014611400467.99
189 rdf:rest Nda4679700f3a4ccd96c8192344e29ec6
190 Nffdfcce670264e9e8cd899a385b838cc rdf:first sg:person.0647017707.55
191 rdf:rest Ne9888658a0e645189ecc3f2d3d6fd85c
192 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
193 schema:name Medical and Health Sciences
194 rdf:type schema:DefinedTerm
195 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
196 schema:name Clinical Sciences
197 rdf:type schema:DefinedTerm
198 sg:journal.1024958 schema:issn 1471-2482
199 schema:name BMC Surgery
200 rdf:type schema:Periodical
201 sg:person.01000101007.88 schema:affiliation N984d008190c044c1a7f21ababad79dd7
202 schema:familyName Karsten
203 schema:givenName Tom M
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000101007.88
205 rdf:type schema:Person
206 sg:person.01004354234.80 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
207 schema:familyName van Santvoort
208 schema:givenName Hjalmar C
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004354234.80
210 rdf:type schema:Person
211 sg:person.010055554454.90 schema:affiliation https://www.grid.ac/institutes/grid.414846.b
212 schema:familyName Pierie
213 schema:givenName Jean-Pierre EN
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010055554454.90
215 rdf:type schema:Person
216 sg:person.01007165675.69 schema:affiliation https://www.grid.ac/institutes/grid.4494.d
217 schema:familyName Ploeg
218 schema:givenName Rutger J
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007165675.69
220 rdf:type schema:Person
221 sg:person.01075131625.29 schema:affiliation Nf1919e7fe8904a30ac239e26f1854f99
222 schema:familyName Rosman
223 schema:givenName Camiel
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075131625.29
225 rdf:type schema:Person
226 sg:person.011106774542.16 schema:affiliation https://www.grid.ac/institutes/grid.16872.3a
227 schema:familyName Cuesta
228 schema:givenName Miguel A
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011106774542.16
230 rdf:type schema:Person
231 sg:person.01120602634.21 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
232 schema:familyName Besselink
233 schema:givenName Marc GH
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120602634.21
235 rdf:type schema:Person
236 sg:person.011213207434.61 schema:affiliation N2cbda9ce973f42ba9686237b9a40ffae
237 schema:familyName van Laarhoven
238 schema:givenName Cees JHM
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011213207434.61
240 rdf:type schema:Person
241 sg:person.01145111140.65 schema:affiliation https://www.grid.ac/institutes/grid.4494.d
242 schema:familyName Hofker
243 schema:givenName Sijbrand S
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145111140.65
245 rdf:type schema:Person
246 sg:person.012356347224.02 schema:affiliation Nc4c79b71226f4fe6990d74eddf664142
247 schema:familyName Consten
248 schema:givenName Esther CJ
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012356347224.02
250 rdf:type schema:Person
251 sg:person.01245702365.66 schema:affiliation https://www.grid.ac/institutes/grid.415960.f
252 schema:familyName Bollen
253 schema:givenName Thomas L
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245702365.66
255 rdf:type schema:Person
256 sg:person.01260467012.10 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
257 schema:familyName Nieuwenhuijs
258 schema:givenName Vincent B
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260467012.10
260 rdf:type schema:Person
261 sg:person.01315475001.85 schema:affiliation https://www.grid.ac/institutes/grid.5477.1
262 schema:familyName van der Tweel
263 schema:givenName Ingeborg
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315475001.85
265 rdf:type schema:Person
266 sg:person.01317757465.19 schema:affiliation https://www.grid.ac/institutes/grid.415214.7
267 schema:familyName de Wit
268 schema:givenName Ralph J
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317757465.19
270 rdf:type schema:Person
271 sg:person.01362130765.43 schema:affiliation https://www.grid.ac/institutes/grid.415960.f
272 schema:familyName Timmer
273 schema:givenName Robin
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362130765.43
275 rdf:type schema:Person
276 sg:person.01365653063.24 schema:affiliation https://www.grid.ac/institutes/grid.5650.6
277 schema:familyName Lameris
278 schema:givenName Johan S
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365653063.24
280 rdf:type schema:Person
281 sg:person.014611400467.99 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
282 schema:familyName Schaapherder
283 schema:givenName Alexander FM
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014611400467.99
285 rdf:type schema:Person
286 sg:person.015263522637.41 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
287 schema:familyName van Eijck
288 schema:givenName Casper HJ
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015263522637.41
290 rdf:type schema:Person
291 sg:person.015435713307.43 schema:affiliation N41081bbaf1f048228cec62b32737911e
292 schema:familyName Witteman
293 schema:givenName Ben JM
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015435713307.43
295 rdf:type schema:Person
296 sg:person.016643776077.99 schema:affiliation N642f5ba828074575b7e0ac0e9c3d5bdd
297 schema:familyName Dejong
298 schema:givenName Cornelis HC
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016643776077.99
300 rdf:type schema:Person
301 sg:person.0622270010.09 schema:affiliation https://www.grid.ac/institutes/grid.10417.33
302 schema:familyName van Goor
303 schema:givenName Harry
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622270010.09
305 rdf:type schema:Person
306 sg:person.0647017707.55 schema:affiliation https://www.grid.ac/institutes/grid.5650.6
307 schema:familyName Boermeester
308 schema:givenName Marja A
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647017707.55
310 rdf:type schema:Person
311 sg:person.0650623704.27 schema:affiliation https://www.grid.ac/institutes/grid.5650.6
312 schema:familyName Gouma
313 schema:givenName Dirk J
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650623704.27
315 rdf:type schema:Person
316 sg:person.0661463615.08 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
317 schema:familyName Buskens
318 schema:givenName Erik
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661463615.08
320 rdf:type schema:Person
321 sg:person.0667406735.21 schema:familyName van Leeuwen
322 schema:givenName Maarten S
323 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0667406735.21
324 rdf:type schema:Person
325 sg:person.0673766734.92 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
326 schema:familyName Gooszen
327 schema:givenName Hein G
328 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673766734.92
329 rdf:type schema:Person
330 sg:person.0710630520.06 schema:affiliation https://www.grid.ac/institutes/grid.414828.3
331 schema:familyName Houdijk
332 schema:givenName Lex PJ
333 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710630520.06
334 rdf:type schema:Person
335 sg:person.0717210535.99 schema:affiliation https://www.grid.ac/institutes/grid.415930.a
336 schema:familyName Bilgen
337 schema:givenName Ernst Jan Spillenaar
338 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717210535.99
339 rdf:type schema:Person
340 sg:person.0756446730.73 schema:affiliation https://www.grid.ac/institutes/grid.415960.f
341 schema:familyName van Ramshorst
342 schema:givenName Bert
343 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756446730.73
344 rdf:type schema:Person
345 sg:pub.10.1007/bf01709751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052044737
346 https://doi.org/10.1007/bf01709751
347 rdf:type schema:CreativeWork
348 sg:pub.10.1007/s004640080166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029907401
349 https://doi.org/10.1007/s004640080166
350 rdf:type schema:CreativeWork
351 sg:pub.10.1186/1471-2482-4-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017799402
352 https://doi.org/10.1186/1471-2482-4-12
353 rdf:type schema:CreativeWork
354 https://app.dimensions.ai/details/publication/pub.1077026500 schema:CreativeWork
355 https://doi.org/10.1001/archsurg.1993.01420170122019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015767287
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1002/bjs.1800750306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006375562
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1002/bjs.5287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047282225
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1016/s0001-4001(99)80039-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024736417
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1016/s0002-9610(96)00425-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020261833
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1016/s0016-5107(05)00541-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015525012
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1016/s1051-0443(98)70323-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013259893
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1046/j.1440-1746.17.s1.2.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021754604
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1053/gast.1996.v111.pm8780582 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050513438
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1080/00855920310002799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058289175
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1097/00000658-200008000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052624714
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1097/00003246-199811000-00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060173147
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1097/01.sla.0000188462.00249.36 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004179108
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1136/bmj.38118.593900.55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031677825
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1136/gut.2003.035907 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043577916
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1136/gut.2004.057026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010523554
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1159/000071184 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016959571
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1159/000071269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052011841
390 rdf:type schema:CreativeWork
391 https://doi.org/10.2214/ajr.170.4.9530046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069321544
392 rdf:type schema:CreativeWork
393 https://doi.org/10.2214/ajr.170.4.9530047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069321545
394 rdf:type schema:CreativeWork
395 https://www.grid.ac/institutes/grid.10417.33 schema:alternateName Radboud University Nijmegen Medical Centre
396 schema:name Department of Surgery, Radboud University Nijmegen Medical Centre, The Netherlands
397 rdf:type schema:Organization
398 https://www.grid.ac/institutes/grid.10419.3d schema:alternateName Leiden University Medical Center
399 schema:name Department of Surgery, Leiden University Medical Center, The Netherlands
400 rdf:type schema:Organization
401 https://www.grid.ac/institutes/grid.16872.3a schema:alternateName VU University Medical Center
402 schema:name Department of Surgery, VU Medical Center Amsterdam, The Netherlands
403 rdf:type schema:Organization
404 https://www.grid.ac/institutes/grid.414828.3 schema:alternateName Medisch Centrum Alkmaar
405 schema:name Department of Surgery, Medical Center Alkmaar, The Netherlands
406 rdf:type schema:Organization
407 https://www.grid.ac/institutes/grid.414846.b schema:alternateName Medisch Centrum Leeuwarden
408 schema:name Department of Surgery, Medical Center Leeuwarden, The Netherlands
409 rdf:type schema:Organization
410 https://www.grid.ac/institutes/grid.415214.7 schema:alternateName Medisch Spectrum Twente
411 schema:name Department of Surgery, Medical Spectrum Twente, Enschede, The Netherlands
412 rdf:type schema:Organization
413 https://www.grid.ac/institutes/grid.415930.a schema:alternateName Rijnstate Hospital
414 schema:name Department of Surgery, Rijnstate Hospital Arnhem, The Netherlands
415 rdf:type schema:Organization
416 https://www.grid.ac/institutes/grid.415960.f schema:alternateName St. Antonius Ziekenhuis
417 schema:name Department of Gastroenterology, St. Antonius Hospital Nieuwegein, The Netherlands
418 Department of Radiology, St. Antonius Hospital Nieuwegein, The Netherlands
419 Department of Surgery, St. Antonius Hospital Nieuwegein, The Netherlands
420 rdf:type schema:Organization
421 https://www.grid.ac/institutes/grid.4494.d schema:alternateName University Medical Center Groningen
422 schema:name Department of Surgery, University Medical Center Groningen, The Netherlands
423 rdf:type schema:Organization
424 https://www.grid.ac/institutes/grid.5477.1 schema:alternateName Utrecht University
425 schema:name Utrecht University, Centre for Biostatistics, The Netherlands
426 rdf:type schema:Organization
427 https://www.grid.ac/institutes/grid.5645.2 schema:alternateName Erasmus University Medical Center
428 schema:name Department of Surgery, Erasmus Medical Center Rotterdam, The Netherlands
429 rdf:type schema:Organization
430 https://www.grid.ac/institutes/grid.5650.6 schema:alternateName Academic Medical Center
431 schema:name Department of Radiology, Academic Medical Center Amsterdam, The Netherlands
432 Department of Surgery, Academic Medical Center Amsterdam, The Netherlands
433 rdf:type schema:Organization
434 https://www.grid.ac/institutes/grid.7692.a schema:alternateName University Medical Center Utrecht
435 schema:name Department of Surgery, University Medical Center Utrecht, The Netherlands
436 Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
437 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...