Effect of home-based interventions on virologic outcomes in adults receiving antiretroviral therapy in Africa: a meta-analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Nathaniel Chishinga, Peter Godfrey-Faussett, Katherine Fielding, Helen Ayles

ABSTRACT

BACKGROUND: The success of adherence to combination antiretroviral therapy (ART) in sub-Saharan Africa is hampered by factors that are unique to this setting. Home based interventions have been identified as possible strategies for decentralizing ART care and improving access and adherence to ART. There is need for evidence at individual- or community-level of the benefits of home-based interventions in improving HIV suppression in African patients receiving ART. METHODS: We conducted a systematic review and meta-analysis of the literature to assess the effect of home-based interventions on virologic outcomes in adults receiving ART in Africa. RESULTS: A total of 260 publications were identified by the search strategy, 249 were excluded on initial screening and 11 on full review, leaving 5 publications for analysis. The overall OR of virologic suppression at 12 months after starting ART of home-based interventions to standard of care was 1.13 (95% CI: 0.51-2.52). CONCLUSIONS: There was insufficient data to know whether there is a difference in HIV suppression at 12 months in the home-based arm compared with the standard of care arm in adults receiving ART in Africa. Given the few trials conducted from Africa, there is need for further research that measures the effects of home-based models on HIV suppression in African populations. More... »

PAGES

239

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2458-14-239

DOI

http://dx.doi.org/10.1186/1471-2458-14-239

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047435307

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24606968


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Africa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-HIV Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Health Services Needs and Demand", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "House Calls", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Medication Adherence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Randomized Controlled Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Viral Load", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "London School of Hygiene & Tropical Medicine", 
          "id": "https://www.grid.ac/institutes/grid.8991.9", 
          "name": [
            "Zambia AIDS-related TB Project, School of Medicine, Ridgeway campus, P.O Box 50697, Lusaka, Zambia", 
            "Department of Clinical Research, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chishinga", 
        "givenName": "Nathaniel", 
        "id": "sg:person.01037727574.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037727574.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "London School of Hygiene & Tropical Medicine", 
          "id": "https://www.grid.ac/institutes/grid.8991.9", 
          "name": [
            "Department of Clinical Research, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Godfrey-Faussett", 
        "givenName": "Peter", 
        "id": "sg:person.01220473665.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220473665.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "London School of Hygiene & Tropical Medicine", 
          "id": "https://www.grid.ac/institutes/grid.8991.9", 
          "name": [
            "Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fielding", 
        "givenName": "Katherine", 
        "id": "sg:person.015776616037.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015776616037.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "London School of Hygiene & Tropical Medicine", 
          "id": "https://www.grid.ac/institutes/grid.8991.9", 
          "name": [
            "Zambia AIDS-related TB Project, School of Medicine, Ridgeway campus, P.O Box 50697, Lusaka, Zambia", 
            "Department of Clinical Research, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ayles", 
        "givenName": "Helen", 
        "id": "sg:person.0702777076.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702777076.09"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/qai.0b013e318153f7ba", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002465445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e318153f7ba", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002465445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/heapol/czq005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003771689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/323201", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004476574"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/340197", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006443900"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1745-6215-9-21", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007233867", 
          "https://doi.org/10.1186/1745-6215-9-21"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181d9a330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007303861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181d9a330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007303861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181d9a330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007303861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181d9a330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007303861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/322590", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007682658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1061-9259(97)80026-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008000295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)61991-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009051214"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/09540121.2010.532531", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010685451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200309050-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011504375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200309050-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011504375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32831c5562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013164247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32831c5562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013164247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)62067-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013718445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181ff0bdc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013821901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181ff0bdc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013821901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181ff0bdc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013821901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181ff0bdc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013821901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200003100-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017542612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200003100-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017542612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200003100-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017542612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3182207a3f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017595509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3182207a3f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017595509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(10)61997-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018020284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/09540121.2010.498909", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018842041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(06)69118-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019458658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000371678.25873.1c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026424505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000371678.25873.1c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026424505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000371678.25873.1c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026424505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181806bf1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027935072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181806bf1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027935072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181806bf1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027935072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181988375", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028732722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e3181988375", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028732722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1874613600701010021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032085022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd005417.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033576533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000248349.25630.3d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034792741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000248349.25630.3d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034792741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200205030-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035413913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200205030-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035413913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e328339e20e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035510315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e328339e20e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035510315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)61674-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036328444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200410210-00023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036381782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200410210-00023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036381782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200201250-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037888907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200201250-00017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037888907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3156.2008.02131.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044894829"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/095646207782212252", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045926410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/095646207782212252", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045926410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.socscimed.2009.07.034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046211197"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0010923", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046902054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-200205010-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047152062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)61671-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047575111"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/09540120902814395", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051546533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/466526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058751177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/apc.2007.0213", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059228870"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/apc.2010.0349", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059229281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/157016210790442722", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069197762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-133-1-200007040-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073704135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074820136", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074983426", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077173270", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.2009.80.669", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077882245"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-12", 
    "datePublishedReg": "2014-12-01", 
    "description": "BACKGROUND: The success of adherence to combination antiretroviral therapy (ART) in sub-Saharan Africa is hampered by factors that are unique to this setting. Home based interventions have been identified as possible strategies for decentralizing ART care and improving access and adherence to ART. There is need for evidence at individual- or community-level of the benefits of home-based interventions in improving HIV suppression in African patients receiving ART.\nMETHODS: We conducted a systematic review and meta-analysis of the literature to assess the effect of home-based interventions on virologic outcomes in adults receiving ART in Africa.\nRESULTS: A total of 260 publications were identified by the search strategy, 249 were excluded on initial screening and 11 on full review, leaving 5 publications for analysis. The overall OR of virologic suppression at 12 months after starting ART of home-based interventions to standard of care was 1.13 (95% CI: 0.51-2.52).\nCONCLUSIONS: There was insufficient data to know whether there is a difference in HIV suppression at 12 months in the home-based arm compared with the standard of care arm in adults receiving ART in Africa. Given the few trials conducted from Africa, there is need for further research that measures the effects of home-based models on HIV suppression in African populations.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2458-14-239", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6586317", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3498121", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1024954", 
        "issn": [
          "1471-2458"
        ], 
        "name": "BMC Public Health", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "14"
      }
    ], 
    "name": "Effect of home-based interventions on virologic outcomes in adults receiving antiretroviral therapy in Africa: a meta-analysis", 
    "pagination": "239", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e1f7757dea69509011e520b871767d51882cf0bae8dd87c9df1d2fa4200a9b4d"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24606968"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968562"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2458-14-239"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1047435307"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2458-14-239", 
      "https://app.dimensions.ai/details/publication/pub.1047435307"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000515.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2458-14-239"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2458-14-239'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2458-14-239'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2458-14-239'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2458-14-239'


 

This table displays all metadata directly associated to this object as RDF triples.

275 TRIPLES      21 PREDICATES      86 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2458-14-239 schema:about N1c40a55f43bb494187958051bb41ab47
2 N35aabd93487740a9b58924783e58b467
3 N3c32c71105734494957076576274d1b4
4 N4764bd77eb8b438081a5f7862132e764
5 N658d11aa541e4a06bddec3657ced8c33
6 N96fb1502b6d249a29e7d4fa5e9355857
7 N9a99f193b19f4fb3b65c4fdac9318d6b
8 Na6e0c11c77b94b519568cb176d8c7997
9 Naf667ce587df45a7b8b93bc12b1e6be8
10 Nbb3c871a95f64f9298aa42f1109b3903
11 Nfe6f0093a84541dc8c13423f60bc27b4
12 anzsrc-for:11
13 anzsrc-for:1117
14 schema:author Nd3b11bdae906419a921f5086f55a895d
15 schema:citation sg:pub.10.1186/1745-6215-9-21
16 https://app.dimensions.ai/details/publication/pub.1074820136
17 https://app.dimensions.ai/details/publication/pub.1074983426
18 https://app.dimensions.ai/details/publication/pub.1077173270
19 https://doi.org/10.1002/14651858.cd005417.pub2
20 https://doi.org/10.1016/j.socscimed.2009.07.034
21 https://doi.org/10.1016/s0140-6736(06)69118-6
22 https://doi.org/10.1016/s0140-6736(09)61671-8
23 https://doi.org/10.1016/s0140-6736(09)61674-3
24 https://doi.org/10.1016/s0140-6736(09)61991-7
25 https://doi.org/10.1016/s0140-6736(09)62067-5
26 https://doi.org/10.1016/s0140-6736(10)61997-6
27 https://doi.org/10.1016/s1061-9259(97)80026-4
28 https://doi.org/10.1080/09540120902814395
29 https://doi.org/10.1080/09540121.2010.498909
30 https://doi.org/10.1080/09540121.2010.532531
31 https://doi.org/10.1086/322590
32 https://doi.org/10.1086/323201
33 https://doi.org/10.1086/340197
34 https://doi.org/10.1086/466526
35 https://doi.org/10.1089/apc.2007.0213
36 https://doi.org/10.1089/apc.2010.0349
37 https://doi.org/10.1093/heapol/czq005
38 https://doi.org/10.1097/00002030-200003100-00008
39 https://doi.org/10.1097/00002030-200201250-00017
40 https://doi.org/10.1097/00002030-200205030-00012
41 https://doi.org/10.1097/00002030-200309050-00011
42 https://doi.org/10.1097/00002030-200410210-00023
43 https://doi.org/10.1097/00042560-200205010-00014
44 https://doi.org/10.1097/01.qai.0000248349.25630.3d
45 https://doi.org/10.1097/01.qai.0000371678.25873.1c
46 https://doi.org/10.1097/qad.0b013e32831c5562
47 https://doi.org/10.1097/qad.0b013e328339e20e
48 https://doi.org/10.1097/qai.0b013e318153f7ba
49 https://doi.org/10.1097/qai.0b013e3181806bf1
50 https://doi.org/10.1097/qai.0b013e3181988375
51 https://doi.org/10.1097/qai.0b013e3181d9a330
52 https://doi.org/10.1097/qai.0b013e3181ff0bdc
53 https://doi.org/10.1097/qai.0b013e3182207a3f
54 https://doi.org/10.1111/j.1365-3156.2008.02131.x
55 https://doi.org/10.1258/095646207782212252
56 https://doi.org/10.1371/journal.pone.0010923
57 https://doi.org/10.2174/157016210790442722
58 https://doi.org/10.2174/1874613600701010021
59 https://doi.org/10.4269/ajtmh.2009.80.669
60 https://doi.org/10.7326/0003-4819-133-1-200007040-00004
61 schema:datePublished 2014-12
62 schema:datePublishedReg 2014-12-01
63 schema:description BACKGROUND: The success of adherence to combination antiretroviral therapy (ART) in sub-Saharan Africa is hampered by factors that are unique to this setting. Home based interventions have been identified as possible strategies for decentralizing ART care and improving access and adherence to ART. There is need for evidence at individual- or community-level of the benefits of home-based interventions in improving HIV suppression in African patients receiving ART. METHODS: We conducted a systematic review and meta-analysis of the literature to assess the effect of home-based interventions on virologic outcomes in adults receiving ART in Africa. RESULTS: A total of 260 publications were identified by the search strategy, 249 were excluded on initial screening and 11 on full review, leaving 5 publications for analysis. The overall OR of virologic suppression at 12 months after starting ART of home-based interventions to standard of care was 1.13 (95% CI: 0.51-2.52). CONCLUSIONS: There was insufficient data to know whether there is a difference in HIV suppression at 12 months in the home-based arm compared with the standard of care arm in adults receiving ART in Africa. Given the few trials conducted from Africa, there is need for further research that measures the effects of home-based models on HIV suppression in African populations.
64 schema:genre research_article
65 schema:inLanguage en
66 schema:isAccessibleForFree true
67 schema:isPartOf N2dd027705bd049d9bad5546d10e9b705
68 N8d9651ca67e444b8bce93405c2a1dbb4
69 sg:journal.1024954
70 schema:name Effect of home-based interventions on virologic outcomes in adults receiving antiretroviral therapy in Africa: a meta-analysis
71 schema:pagination 239
72 schema:productId N367de23abe6141928173d1a8410cd16a
73 N8899d823e1eb4bc4a769ab995f1c8ed2
74 Nb4381baad7b046b2aaee179135abaa31
75 Nd7c8b46cc5be4462a190c64d362ed4ca
76 Nf45d862d5f80442588160aebb536ad8f
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047435307
78 https://doi.org/10.1186/1471-2458-14-239
79 schema:sdDatePublished 2019-04-10T20:48
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher N1341eb822ac14e43912f2395b71f6a65
82 schema:url http://link.springer.com/10.1186%2F1471-2458-14-239
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N1341eb822ac14e43912f2395b71f6a65 schema:name Springer Nature - SN SciGraph project
87 rdf:type schema:Organization
88 N1c40a55f43bb494187958051bb41ab47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Randomized Controlled Trials as Topic
90 rdf:type schema:DefinedTerm
91 N27190e5af7d0415187a3160b88354ff8 rdf:first sg:person.0702777076.09
92 rdf:rest rdf:nil
93 N2dd027705bd049d9bad5546d10e9b705 schema:volumeNumber 14
94 rdf:type schema:PublicationVolume
95 N35aabd93487740a9b58924783e58b467 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Health Services Needs and Demand
97 rdf:type schema:DefinedTerm
98 N367de23abe6141928173d1a8410cd16a schema:name pubmed_id
99 schema:value 24606968
100 rdf:type schema:PropertyValue
101 N3c32c71105734494957076576274d1b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name HIV Infections
103 rdf:type schema:DefinedTerm
104 N4764bd77eb8b438081a5f7862132e764 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Anti-HIV Agents
106 rdf:type schema:DefinedTerm
107 N4b7311e4a82341bcb3c70abe96bfed0b rdf:first sg:person.015776616037.35
108 rdf:rest N27190e5af7d0415187a3160b88354ff8
109 N658d11aa541e4a06bddec3657ced8c33 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Humans
111 rdf:type schema:DefinedTerm
112 N6c3b6e9015044c6f8c47a60c3a09849d rdf:first sg:person.01220473665.47
113 rdf:rest N4b7311e4a82341bcb3c70abe96bfed0b
114 N8899d823e1eb4bc4a769ab995f1c8ed2 schema:name doi
115 schema:value 10.1186/1471-2458-14-239
116 rdf:type schema:PropertyValue
117 N8d9651ca67e444b8bce93405c2a1dbb4 schema:issueNumber 1
118 rdf:type schema:PublicationIssue
119 N96fb1502b6d249a29e7d4fa5e9355857 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Viral Load
121 rdf:type schema:DefinedTerm
122 N9a99f193b19f4fb3b65c4fdac9318d6b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name House Calls
124 rdf:type schema:DefinedTerm
125 Na6e0c11c77b94b519568cb176d8c7997 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Africa
127 rdf:type schema:DefinedTerm
128 Naf667ce587df45a7b8b93bc12b1e6be8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Treatment Outcome
130 rdf:type schema:DefinedTerm
131 Nb4381baad7b046b2aaee179135abaa31 schema:name nlm_unique_id
132 schema:value 100968562
133 rdf:type schema:PropertyValue
134 Nbb3c871a95f64f9298aa42f1109b3903 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Adult
136 rdf:type schema:DefinedTerm
137 Nd3b11bdae906419a921f5086f55a895d rdf:first sg:person.01037727574.33
138 rdf:rest N6c3b6e9015044c6f8c47a60c3a09849d
139 Nd7c8b46cc5be4462a190c64d362ed4ca schema:name dimensions_id
140 schema:value pub.1047435307
141 rdf:type schema:PropertyValue
142 Nf45d862d5f80442588160aebb536ad8f schema:name readcube_id
143 schema:value e1f7757dea69509011e520b871767d51882cf0bae8dd87c9df1d2fa4200a9b4d
144 rdf:type schema:PropertyValue
145 Nfe6f0093a84541dc8c13423f60bc27b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Medication Adherence
147 rdf:type schema:DefinedTerm
148 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
149 schema:name Medical and Health Sciences
150 rdf:type schema:DefinedTerm
151 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
152 schema:name Public Health and Health Services
153 rdf:type schema:DefinedTerm
154 sg:grant.3498121 http://pending.schema.org/fundedItem sg:pub.10.1186/1471-2458-14-239
155 rdf:type schema:MonetaryGrant
156 sg:grant.6586317 http://pending.schema.org/fundedItem sg:pub.10.1186/1471-2458-14-239
157 rdf:type schema:MonetaryGrant
158 sg:journal.1024954 schema:issn 1471-2458
159 schema:name BMC Public Health
160 rdf:type schema:Periodical
161 sg:person.01037727574.33 schema:affiliation https://www.grid.ac/institutes/grid.8991.9
162 schema:familyName Chishinga
163 schema:givenName Nathaniel
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037727574.33
165 rdf:type schema:Person
166 sg:person.01220473665.47 schema:affiliation https://www.grid.ac/institutes/grid.8991.9
167 schema:familyName Godfrey-Faussett
168 schema:givenName Peter
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220473665.47
170 rdf:type schema:Person
171 sg:person.015776616037.35 schema:affiliation https://www.grid.ac/institutes/grid.8991.9
172 schema:familyName Fielding
173 schema:givenName Katherine
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015776616037.35
175 rdf:type schema:Person
176 sg:person.0702777076.09 schema:affiliation https://www.grid.ac/institutes/grid.8991.9
177 schema:familyName Ayles
178 schema:givenName Helen
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702777076.09
180 rdf:type schema:Person
181 sg:pub.10.1186/1745-6215-9-21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007233867
182 https://doi.org/10.1186/1745-6215-9-21
183 rdf:type schema:CreativeWork
184 https://app.dimensions.ai/details/publication/pub.1074820136 schema:CreativeWork
185 https://app.dimensions.ai/details/publication/pub.1074983426 schema:CreativeWork
186 https://app.dimensions.ai/details/publication/pub.1077173270 schema:CreativeWork
187 https://doi.org/10.1002/14651858.cd005417.pub2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033576533
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/j.socscimed.2009.07.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046211197
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/s0140-6736(06)69118-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019458658
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/s0140-6736(09)61671-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047575111
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/s0140-6736(09)61674-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036328444
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/s0140-6736(09)61991-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009051214
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/s0140-6736(09)62067-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013718445
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/s0140-6736(10)61997-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018020284
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/s1061-9259(97)80026-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008000295
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1080/09540120902814395 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051546533
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1080/09540121.2010.498909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018842041
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1080/09540121.2010.532531 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010685451
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1086/322590 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007682658
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1086/323201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004476574
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1086/340197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006443900
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1086/466526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058751177
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1089/apc.2007.0213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059228870
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1089/apc.2010.0349 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059229281
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1093/heapol/czq005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003771689
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1097/00002030-200003100-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017542612
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1097/00002030-200201250-00017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037888907
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1097/00002030-200205030-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035413913
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1097/00002030-200309050-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011504375
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1097/00002030-200410210-00023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036381782
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1097/00042560-200205010-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047152062
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1097/01.qai.0000248349.25630.3d schema:sameAs https://app.dimensions.ai/details/publication/pub.1034792741
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1097/01.qai.0000371678.25873.1c schema:sameAs https://app.dimensions.ai/details/publication/pub.1026424505
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1097/qad.0b013e32831c5562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013164247
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1097/qad.0b013e328339e20e schema:sameAs https://app.dimensions.ai/details/publication/pub.1035510315
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1097/qai.0b013e318153f7ba schema:sameAs https://app.dimensions.ai/details/publication/pub.1002465445
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1097/qai.0b013e3181806bf1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027935072
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1097/qai.0b013e3181988375 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028732722
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1097/qai.0b013e3181d9a330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007303861
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1097/qai.0b013e3181ff0bdc schema:sameAs https://app.dimensions.ai/details/publication/pub.1013821901
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1097/qai.0b013e3182207a3f schema:sameAs https://app.dimensions.ai/details/publication/pub.1017595509
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1111/j.1365-3156.2008.02131.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044894829
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1258/095646207782212252 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045926410
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1371/journal.pone.0010923 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046902054
262 rdf:type schema:CreativeWork
263 https://doi.org/10.2174/157016210790442722 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069197762
264 rdf:type schema:CreativeWork
265 https://doi.org/10.2174/1874613600701010021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032085022
266 rdf:type schema:CreativeWork
267 https://doi.org/10.4269/ajtmh.2009.80.669 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077882245
268 rdf:type schema:CreativeWork
269 https://doi.org/10.7326/0003-4819-133-1-200007040-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073704135
270 rdf:type schema:CreativeWork
271 https://www.grid.ac/institutes/grid.8991.9 schema:alternateName London School of Hygiene & Tropical Medicine
272 schema:name Department of Clinical Research, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK
273 Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK
274 Zambia AIDS-related TB Project, School of Medicine, Ridgeway campus, P.O Box 50697, Lusaka, Zambia
275 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...