Does the use of the 2009 FIGO classification of endometrial cancer impact on indications of the sentinel node biopsy? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-12

AUTHORS

Marcos Ballester, Martin Koskas, Charles Coutant, Elisabeth Chéreau, Jeremy Seror, Roman Rouzier, Emile Daraï

ABSTRACT

BACKGROUND: Lymphadenectomy is debated in early stages endometrial cancer. Moreover, a new FIGO classification of endometrial cancer, merging stages IA and IB has been recently published. Therefore, the aims of the present study was to evaluate the relevance of the sentinel node (SN) procedure in women with endometrial cancer and to discuss whether the use of the 2009 FIGO classification could modify the indications for SN procedure. METHODS: Eighty-five patients with endometrial cancer underwent the SN procedure followed by pelvic lymphadenectomy. SNs were detected with a dual or single labelling method in 74 and 11 cases, respectively. All SNs were analysed by both H&E staining and immunohistochemistry. Presumed stage before surgery was assessed for all patients based on MR imaging features using the 1988 FIGO classification and the 2009 FIGO classification. RESULTS: An SN was detected in 88.2% of cases (75/85 women). Among the fourteen patients with lymph node metastases one-half were detected by serial sectioning and immunohistochemical analysis. There were no false negative case. Using the 1988 FIGO classification and the 2009 FIGO classification, the correlation between preoperative MRI staging and final histology was moderate with Kappa = 0.24 and Kappa = 0.45, respectively. None of the patients with grade 1 endometrioid carcinoma on biopsy and IA 2009 FIGO stage on MR imaging exhibited positive SN. In patients with grade 2-3 endometrioid carcinoma and stage IA on MR imaging, the rate of positive SN reached 16.6% with an incidence of micrometastases of 50%. CONCLUSIONS: The present study suggests that sentinel node biopsy is an adequate technique to evaluate lymph node status. The use of the 2009 FIGO classification increases the accuracy of MR imaging to stage patients with early stages of endometrial cancer and contributes to clarify the indication of SN biopsy according to tumour grade and histological type. More... »

PAGES

465

References to SciGraph publications

  • 2008-05. Use of the Sentinel Node Procedure to Stage Endometrial Cancer in ANNALS OF SURGICAL ONCOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1471-2407-10-465

    DOI

    http://dx.doi.org/10.1186/1471-2407-10-465

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010889807

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20804553


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adenocarcinoma, Clear Cell", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged, 80 and over", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Adenosquamous", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Papillary", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cystadenocarcinoma, Serous", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Endometrial Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "False Negative Reactions", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lymph Nodes", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lymphatic Metastasis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Magnetic Resonance Imaging", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasm Staging", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prognosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sentinel Lymph Node Biopsy", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Survival Rate", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ballester", 
            "givenName": "Marcos", 
            "id": "sg:person.0735113031.79", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735113031.79"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Koskas", 
            "givenName": "Martin", 
            "id": "sg:person.01026235504.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026235504.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Coutant", 
            "givenName": "Charles", 
            "id": "sg:person.01325213233.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325213233.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ch\u00e9reau", 
            "givenName": "Elisabeth", 
            "id": "sg:person.0755060031.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755060031.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Seror", 
            "givenName": "Jeremy", 
            "id": "sg:person.01130505410.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130505410.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rouzier", 
            "givenName": "Roman", 
            "id": "sg:person.01101754741.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101754741.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Service de Gyn\u00e9cologie-Obst\u00e9trique, h\u00f4pital Tenon, AP-HP, CancerEst, Universit\u00e9 Pierre et Marie Curie, Paris VI, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dara\u00ef", 
            "givenName": "Emile", 
            "id": "sg:person.01166567564.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166567564.74"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/j.ijgo.2009.02.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001292099"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1245/s10434-008-9841-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006849110", 
              "https://doi.org/10.1245/s10434-008-9841-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(08)61766-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011544802"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2008.06.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012388042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jso.21200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012464843"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/radiology.216.2.r00au17444", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013200847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00006231-200309000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015880198"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00006231-200309000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015880198"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djn397", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015948446"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2007.01.021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018106604"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2009.07.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018599781"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.suronc.2008.04.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020549545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1525-1438.2007.00909.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021489579"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1525-1438.2007.00909.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021489579"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ejogrb.2008.12.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022045935"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1067/mob.2000.107335", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024632192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jso.20857", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032843935"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2007.03.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033213556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.suronc.2008.04.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035729501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2009.04.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037101374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/gyno.2000.6067", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037212982"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2005.06.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038152029"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2006.07.033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041050983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cncr.2820710409", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041286001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2009.01.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044167658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijgo.2009.02.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044853788"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/gyno.2000.6111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047134670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2003.10.039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050674750"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2005.01.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050834018"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygyno.2007.01.052", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050899698"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/annonc/mdm334", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051628396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19901015)60:8+<2035::aid-cncr2820601515>3.0.co;2-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052966103"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1200/jco.2002.02.026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064202917"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076846436", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076942199", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-12", 
        "datePublishedReg": "2010-12-01", 
        "description": "BACKGROUND: Lymphadenectomy is debated in early stages endometrial cancer. Moreover, a new FIGO classification of endometrial cancer, merging stages IA and IB has been recently published. Therefore, the aims of the present study was to evaluate the relevance of the sentinel node (SN) procedure in women with endometrial cancer and to discuss whether the use of the 2009 FIGO classification could modify the indications for SN procedure.\nMETHODS: Eighty-five patients with endometrial cancer underwent the SN procedure followed by pelvic lymphadenectomy. SNs were detected with a dual or single labelling method in 74 and 11 cases, respectively. All SNs were analysed by both H&E staining and immunohistochemistry. Presumed stage before surgery was assessed for all patients based on MR imaging features using the 1988 FIGO classification and the 2009 FIGO classification.\nRESULTS: An SN was detected in 88.2% of cases (75/85 women). Among the fourteen patients with lymph node metastases one-half were detected by serial sectioning and immunohistochemical analysis. There were no false negative case. Using the 1988 FIGO classification and the 2009 FIGO classification, the correlation between preoperative MRI staging and final histology was moderate with Kappa = 0.24 and Kappa = 0.45, respectively. None of the patients with grade 1 endometrioid carcinoma on biopsy and IA 2009 FIGO stage on MR imaging exhibited positive SN. In patients with grade 2-3 endometrioid carcinoma and stage IA on MR imaging, the rate of positive SN reached 16.6% with an incidence of micrometastases of 50%.\nCONCLUSIONS: The present study suggests that sentinel node biopsy is an adequate technique to evaluate lymph node status. The use of the 2009 FIGO classification increases the accuracy of MR imaging to stage patients with early stages of endometrial cancer and contributes to clarify the indication of SN biopsy according to tumour grade and histological type.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/1471-2407-10-465", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1024632", 
            "issn": [
              "1471-2407"
            ], 
            "name": "BMC Cancer", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "10"
          }
        ], 
        "name": "Does the use of the 2009 FIGO classification of endometrial cancer impact on indications of the sentinel node biopsy?", 
        "pagination": "465", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "33e1ab58ed328246d9e49cecb30a8372742bb911da3795cbe0834cd1725c609e"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "20804553"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "100967800"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/1471-2407-10-465"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1010889807"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/1471-2407-10-465", 
          "https://app.dimensions.ai/details/publication/pub.1010889807"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T00:15", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000511.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1186%2F1471-2407-10-465"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2407-10-465'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2407-10-465'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2407-10-465'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2407-10-465'


     

    This table displays all metadata directly associated to this object as RDF triples.

    299 TRIPLES      21 PREDICATES      82 URIs      41 LITERALS      29 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/1471-2407-10-465 schema:about N11654d1777104b27a22fb9c58ccff5af
    2 N1642bc5295774fe4ba2c2f35e2dc4b9f
    3 N2c3aba5a447e47cab8c5302273502857
    4 N4b9b75a0824144acb1f69cd67d85c543
    5 N4f24833c8984444589e207e107ff34c9
    6 N5272a2f2a7d14c2291641b4281fd707c
    7 N574c33d52fe548348bcf56f46840e797
    8 N921da91e252147fdb6a1450a6e00adec
    9 N93b6f088970040c7a73754897fa9df5d
    10 N9fc54e650c6c435cb2c4a55502bc7735
    11 Na0ca329b034744969a672937501582df
    12 Na8cbe803a97d498fa0266816f7a91d4c
    13 Nacda5837cd4a4158b170ba8a2e9d580f
    14 Nc4f165f549c8479798e0abe09ee3fd1b
    15 Nc95c5e4c500c490a87eddb21910ebe3b
    16 Nd440c26013ef416e8d6a4e5d1126796c
    17 Nd890e9cbce9a46258489656b111efed4
    18 Ndaae040620e240428e01c5835aef9cf8
    19 Ndb94a920e07a44149e4172167eb3d2e9
    20 Nf298d0fc4de8471b921b584296e83941
    21 anzsrc-for:11
    22 anzsrc-for:1112
    23 schema:author Nd88c2fb59e7b4bb5ac34b0eea9ee27d1
    24 schema:citation sg:pub.10.1245/s10434-008-9841-1
    25 https://app.dimensions.ai/details/publication/pub.1076846436
    26 https://app.dimensions.ai/details/publication/pub.1076942199
    27 https://doi.org/10.1002/1097-0142(19901015)60:8+<2035::aid-cncr2820601515>3.0.co;2-8
    28 https://doi.org/10.1002/cncr.2820710409
    29 https://doi.org/10.1002/jso.20857
    30 https://doi.org/10.1002/jso.21200
    31 https://doi.org/10.1006/gyno.2000.6067
    32 https://doi.org/10.1006/gyno.2000.6111
    33 https://doi.org/10.1016/j.ejogrb.2008.12.015
    34 https://doi.org/10.1016/j.ijgo.2009.02.008
    35 https://doi.org/10.1016/j.ijgo.2009.02.010
    36 https://doi.org/10.1016/j.suronc.2008.04.001
    37 https://doi.org/10.1016/j.suronc.2008.04.002
    38 https://doi.org/10.1016/j.ygyno.2003.10.039
    39 https://doi.org/10.1016/j.ygyno.2005.01.004
    40 https://doi.org/10.1016/j.ygyno.2005.06.010
    41 https://doi.org/10.1016/j.ygyno.2006.07.033
    42 https://doi.org/10.1016/j.ygyno.2007.01.021
    43 https://doi.org/10.1016/j.ygyno.2007.01.052
    44 https://doi.org/10.1016/j.ygyno.2007.03.003
    45 https://doi.org/10.1016/j.ygyno.2008.06.009
    46 https://doi.org/10.1016/j.ygyno.2009.01.003
    47 https://doi.org/10.1016/j.ygyno.2009.04.020
    48 https://doi.org/10.1016/j.ygyno.2009.07.016
    49 https://doi.org/10.1016/s0140-6736(08)61766-3
    50 https://doi.org/10.1067/mob.2000.107335
    51 https://doi.org/10.1093/annonc/mdm334
    52 https://doi.org/10.1093/jnci/djn397
    53 https://doi.org/10.1097/00006231-200309000-00005
    54 https://doi.org/10.1111/j.1525-1438.2007.00909.x
    55 https://doi.org/10.1148/radiology.216.2.r00au17444
    56 https://doi.org/10.1200/jco.2002.02.026
    57 schema:datePublished 2010-12
    58 schema:datePublishedReg 2010-12-01
    59 schema:description BACKGROUND: Lymphadenectomy is debated in early stages endometrial cancer. Moreover, a new FIGO classification of endometrial cancer, merging stages IA and IB has been recently published. Therefore, the aims of the present study was to evaluate the relevance of the sentinel node (SN) procedure in women with endometrial cancer and to discuss whether the use of the 2009 FIGO classification could modify the indications for SN procedure. METHODS: Eighty-five patients with endometrial cancer underwent the SN procedure followed by pelvic lymphadenectomy. SNs were detected with a dual or single labelling method in 74 and 11 cases, respectively. All SNs were analysed by both H&E staining and immunohistochemistry. Presumed stage before surgery was assessed for all patients based on MR imaging features using the 1988 FIGO classification and the 2009 FIGO classification. RESULTS: An SN was detected in 88.2% of cases (75/85 women). Among the fourteen patients with lymph node metastases one-half were detected by serial sectioning and immunohistochemical analysis. There were no false negative case. Using the 1988 FIGO classification and the 2009 FIGO classification, the correlation between preoperative MRI staging and final histology was moderate with Kappa = 0.24 and Kappa = 0.45, respectively. None of the patients with grade 1 endometrioid carcinoma on biopsy and IA 2009 FIGO stage on MR imaging exhibited positive SN. In patients with grade 2-3 endometrioid carcinoma and stage IA on MR imaging, the rate of positive SN reached 16.6% with an incidence of micrometastases of 50%. CONCLUSIONS: The present study suggests that sentinel node biopsy is an adequate technique to evaluate lymph node status. The use of the 2009 FIGO classification increases the accuracy of MR imaging to stage patients with early stages of endometrial cancer and contributes to clarify the indication of SN biopsy according to tumour grade and histological type.
    60 schema:genre research_article
    61 schema:inLanguage en
    62 schema:isAccessibleForFree true
    63 schema:isPartOf N78ae4d6b66744d6dac60ff41260baf61
    64 Nced2a4a4647a40d394bd438e962f50ea
    65 sg:journal.1024632
    66 schema:name Does the use of the 2009 FIGO classification of endometrial cancer impact on indications of the sentinel node biopsy?
    67 schema:pagination 465
    68 schema:productId N41fdcb044021460d84fca49137575305
    69 N432fa60b9dcd48a78d90e93ade059482
    70 N6c0cdf5b592e4495b236ce0b656ba38f
    71 Nbc77acdd64d6451c905cca89a150c903
    72 Nedf2a1cbff6f4f388ae25e0f79b55cb8
    73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010889807
    74 https://doi.org/10.1186/1471-2407-10-465
    75 schema:sdDatePublished 2019-04-11T00:15
    76 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    77 schema:sdPublisher N60c2dfd830274a4887a7b123a4f80547
    78 schema:url http://link.springer.com/10.1186%2F1471-2407-10-465
    79 sgo:license sg:explorer/license/
    80 sgo:sdDataset articles
    81 rdf:type schema:ScholarlyArticle
    82 N00c5c2e170be4089954bbed0ad737dd4 rdf:first sg:person.01101754741.17
    83 rdf:rest N0f74cdc6c8db481199d026c9fb8e33ae
    84 N0255010e955441dea19f71f39f828266 rdf:first sg:person.01026235504.67
    85 rdf:rest N8128f278f30e469ea5f5096191140106
    86 N0f74cdc6c8db481199d026c9fb8e33ae rdf:first sg:person.01166567564.74
    87 rdf:rest rdf:nil
    88 N11654d1777104b27a22fb9c58ccff5af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    89 schema:name Female
    90 rdf:type schema:DefinedTerm
    91 N1642bc5295774fe4ba2c2f35e2dc4b9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    92 schema:name Sentinel Lymph Node Biopsy
    93 rdf:type schema:DefinedTerm
    94 N2c3aba5a447e47cab8c5302273502857 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    95 schema:name Carcinoma, Adenosquamous
    96 rdf:type schema:DefinedTerm
    97 N3f6e987676174624b8418b3cb3c78c75 schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    98 rdf:type schema:Organization
    99 N41fdcb044021460d84fca49137575305 schema:name nlm_unique_id
    100 schema:value 100967800
    101 rdf:type schema:PropertyValue
    102 N432fa60b9dcd48a78d90e93ade059482 schema:name doi
    103 schema:value 10.1186/1471-2407-10-465
    104 rdf:type schema:PropertyValue
    105 N4b9b75a0824144acb1f69cd67d85c543 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    106 schema:name Lymph Nodes
    107 rdf:type schema:DefinedTerm
    108 N4f24833c8984444589e207e107ff34c9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    109 schema:name Adult
    110 rdf:type schema:DefinedTerm
    111 N5272a2f2a7d14c2291641b4281fd707c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    112 schema:name Magnetic Resonance Imaging
    113 rdf:type schema:DefinedTerm
    114 N574c33d52fe548348bcf56f46840e797 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Carcinoma, Papillary
    116 rdf:type schema:DefinedTerm
    117 N5ae7d8f5cb1245079ac32363c1e96dfc schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    118 rdf:type schema:Organization
    119 N60c2dfd830274a4887a7b123a4f80547 schema:name Springer Nature - SN SciGraph project
    120 rdf:type schema:Organization
    121 N6932a1b1749a4593bd6c2f77fa86cf2e rdf:first sg:person.01130505410.51
    122 rdf:rest N00c5c2e170be4089954bbed0ad737dd4
    123 N6c0cdf5b592e4495b236ce0b656ba38f schema:name dimensions_id
    124 schema:value pub.1010889807
    125 rdf:type schema:PropertyValue
    126 N6e49e52755d44846ad725241cf57a077 schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    127 rdf:type schema:Organization
    128 N78ae4d6b66744d6dac60ff41260baf61 schema:issueNumber 1
    129 rdf:type schema:PublicationIssue
    130 N8128f278f30e469ea5f5096191140106 rdf:first sg:person.01325213233.35
    131 rdf:rest N86cbd1a109fe40e49ea7c1bcb7f48484
    132 N86cbd1a109fe40e49ea7c1bcb7f48484 rdf:first sg:person.0755060031.11
    133 rdf:rest N6932a1b1749a4593bd6c2f77fa86cf2e
    134 N921da91e252147fdb6a1450a6e00adec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    135 schema:name Prognosis
    136 rdf:type schema:DefinedTerm
    137 N93b6f088970040c7a73754897fa9df5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Survival Rate
    139 rdf:type schema:DefinedTerm
    140 N9fc54e650c6c435cb2c4a55502bc7735 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Cystadenocarcinoma, Serous
    142 rdf:type schema:DefinedTerm
    143 Na0ca329b034744969a672937501582df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Aged
    145 rdf:type schema:DefinedTerm
    146 Na8cbe803a97d498fa0266816f7a91d4c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    147 schema:name Aged, 80 and over
    148 rdf:type schema:DefinedTerm
    149 Nab2d393a9f8a4b6c8d6305aad5970cb3 schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    150 rdf:type schema:Organization
    151 Nacda5837cd4a4158b170ba8a2e9d580f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Humans
    153 rdf:type schema:DefinedTerm
    154 Nbc77acdd64d6451c905cca89a150c903 schema:name readcube_id
    155 schema:value 33e1ab58ed328246d9e49cecb30a8372742bb911da3795cbe0834cd1725c609e
    156 rdf:type schema:PropertyValue
    157 Nc48851e1b9d54943b8b4128cb4bcd76f schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    158 rdf:type schema:Organization
    159 Nc4f165f549c8479798e0abe09ee3fd1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    160 schema:name Adenocarcinoma, Clear Cell
    161 rdf:type schema:DefinedTerm
    162 Nc95c5e4c500c490a87eddb21910ebe3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    163 schema:name False Negative Reactions
    164 rdf:type schema:DefinedTerm
    165 Nce09789bcad7463180e28c15c31763f1 schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    166 rdf:type schema:Organization
    167 Nced2a4a4647a40d394bd438e962f50ea schema:volumeNumber 10
    168 rdf:type schema:PublicationVolume
    169 Nd440c26013ef416e8d6a4e5d1126796c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    170 schema:name Neoplasm Staging
    171 rdf:type schema:DefinedTerm
    172 Nd88c2fb59e7b4bb5ac34b0eea9ee27d1 rdf:first sg:person.0735113031.79
    173 rdf:rest N0255010e955441dea19f71f39f828266
    174 Nd890e9cbce9a46258489656b111efed4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    175 schema:name Risk Factors
    176 rdf:type schema:DefinedTerm
    177 Ndaae040620e240428e01c5835aef9cf8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    178 schema:name Endometrial Neoplasms
    179 rdf:type schema:DefinedTerm
    180 Ndb94a920e07a44149e4172167eb3d2e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Middle Aged
    182 rdf:type schema:DefinedTerm
    183 Nedf2a1cbff6f4f388ae25e0f79b55cb8 schema:name pubmed_id
    184 schema:value 20804553
    185 rdf:type schema:PropertyValue
    186 Nf298d0fc4de8471b921b584296e83941 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    187 schema:name Lymphatic Metastasis
    188 rdf:type schema:DefinedTerm
    189 Nf4c5a535790b47479a930496ae9d570a schema:name Service de Gynécologie-Obstétrique, hôpital Tenon, AP-HP, CancerEst, Université Pierre et Marie Curie, Paris VI, France
    190 rdf:type schema:Organization
    191 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    192 schema:name Medical and Health Sciences
    193 rdf:type schema:DefinedTerm
    194 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    195 schema:name Oncology and Carcinogenesis
    196 rdf:type schema:DefinedTerm
    197 sg:journal.1024632 schema:issn 1471-2407
    198 schema:name BMC Cancer
    199 rdf:type schema:Periodical
    200 sg:person.01026235504.67 schema:affiliation N3f6e987676174624b8418b3cb3c78c75
    201 schema:familyName Koskas
    202 schema:givenName Martin
    203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026235504.67
    204 rdf:type schema:Person
    205 sg:person.01101754741.17 schema:affiliation Nc48851e1b9d54943b8b4128cb4bcd76f
    206 schema:familyName Rouzier
    207 schema:givenName Roman
    208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101754741.17
    209 rdf:type schema:Person
    210 sg:person.01130505410.51 schema:affiliation Nab2d393a9f8a4b6c8d6305aad5970cb3
    211 schema:familyName Seror
    212 schema:givenName Jeremy
    213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130505410.51
    214 rdf:type schema:Person
    215 sg:person.01166567564.74 schema:affiliation Nce09789bcad7463180e28c15c31763f1
    216 schema:familyName Daraï
    217 schema:givenName Emile
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166567564.74
    219 rdf:type schema:Person
    220 sg:person.01325213233.35 schema:affiliation N6e49e52755d44846ad725241cf57a077
    221 schema:familyName Coutant
    222 schema:givenName Charles
    223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325213233.35
    224 rdf:type schema:Person
    225 sg:person.0735113031.79 schema:affiliation N5ae7d8f5cb1245079ac32363c1e96dfc
    226 schema:familyName Ballester
    227 schema:givenName Marcos
    228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735113031.79
    229 rdf:type schema:Person
    230 sg:person.0755060031.11 schema:affiliation Nf4c5a535790b47479a930496ae9d570a
    231 schema:familyName Chéreau
    232 schema:givenName Elisabeth
    233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755060031.11
    234 rdf:type schema:Person
    235 sg:pub.10.1245/s10434-008-9841-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006849110
    236 https://doi.org/10.1245/s10434-008-9841-1
    237 rdf:type schema:CreativeWork
    238 https://app.dimensions.ai/details/publication/pub.1076846436 schema:CreativeWork
    239 https://app.dimensions.ai/details/publication/pub.1076942199 schema:CreativeWork
    240 https://doi.org/10.1002/1097-0142(19901015)60:8+<2035::aid-cncr2820601515>3.0.co;2-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052966103
    241 rdf:type schema:CreativeWork
    242 https://doi.org/10.1002/cncr.2820710409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041286001
    243 rdf:type schema:CreativeWork
    244 https://doi.org/10.1002/jso.20857 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032843935
    245 rdf:type schema:CreativeWork
    246 https://doi.org/10.1002/jso.21200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012464843
    247 rdf:type schema:CreativeWork
    248 https://doi.org/10.1006/gyno.2000.6067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037212982
    249 rdf:type schema:CreativeWork
    250 https://doi.org/10.1006/gyno.2000.6111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047134670
    251 rdf:type schema:CreativeWork
    252 https://doi.org/10.1016/j.ejogrb.2008.12.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022045935
    253 rdf:type schema:CreativeWork
    254 https://doi.org/10.1016/j.ijgo.2009.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001292099
    255 rdf:type schema:CreativeWork
    256 https://doi.org/10.1016/j.ijgo.2009.02.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044853788
    257 rdf:type schema:CreativeWork
    258 https://doi.org/10.1016/j.suronc.2008.04.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035729501
    259 rdf:type schema:CreativeWork
    260 https://doi.org/10.1016/j.suronc.2008.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020549545
    261 rdf:type schema:CreativeWork
    262 https://doi.org/10.1016/j.ygyno.2003.10.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050674750
    263 rdf:type schema:CreativeWork
    264 https://doi.org/10.1016/j.ygyno.2005.01.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050834018
    265 rdf:type schema:CreativeWork
    266 https://doi.org/10.1016/j.ygyno.2005.06.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038152029
    267 rdf:type schema:CreativeWork
    268 https://doi.org/10.1016/j.ygyno.2006.07.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041050983
    269 rdf:type schema:CreativeWork
    270 https://doi.org/10.1016/j.ygyno.2007.01.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018106604
    271 rdf:type schema:CreativeWork
    272 https://doi.org/10.1016/j.ygyno.2007.01.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050899698
    273 rdf:type schema:CreativeWork
    274 https://doi.org/10.1016/j.ygyno.2007.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033213556
    275 rdf:type schema:CreativeWork
    276 https://doi.org/10.1016/j.ygyno.2008.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012388042
    277 rdf:type schema:CreativeWork
    278 https://doi.org/10.1016/j.ygyno.2009.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044167658
    279 rdf:type schema:CreativeWork
    280 https://doi.org/10.1016/j.ygyno.2009.04.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037101374
    281 rdf:type schema:CreativeWork
    282 https://doi.org/10.1016/j.ygyno.2009.07.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018599781
    283 rdf:type schema:CreativeWork
    284 https://doi.org/10.1016/s0140-6736(08)61766-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011544802
    285 rdf:type schema:CreativeWork
    286 https://doi.org/10.1067/mob.2000.107335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024632192
    287 rdf:type schema:CreativeWork
    288 https://doi.org/10.1093/annonc/mdm334 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051628396
    289 rdf:type schema:CreativeWork
    290 https://doi.org/10.1093/jnci/djn397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015948446
    291 rdf:type schema:CreativeWork
    292 https://doi.org/10.1097/00006231-200309000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015880198
    293 rdf:type schema:CreativeWork
    294 https://doi.org/10.1111/j.1525-1438.2007.00909.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021489579
    295 rdf:type schema:CreativeWork
    296 https://doi.org/10.1148/radiology.216.2.r00au17444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013200847
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.1200/jco.2002.02.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064202917
    299 rdf:type schema:CreativeWork
     




    Preview window. Press ESC to close (or click here)


    ...