Characterization of CTX-M ESBLs in Enterobacter cloacae, Escherichia coli and Klebsiella pneumoniae clinical isolates from Cairo, Egypt View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-12

AUTHORS

Noha G Khalaf, Mona M Eletreby, Nancy D Hanson

ABSTRACT

BACKGROUND: A high rate of resistance to 3rd generation cephalosporins among Enterobacteriaceae isolates from Egypt has been previously reported. This study aims to characterize the resistance mechanism (s) to extended spectrum cephalosporins among resistant clinical isolates at a medical institute in Cairo, Egypt. METHODS: Nonconsecutive Klebsiella pneumoniae (Kp), Enterobacter cloacae (ENT) and Escherichia coli (EC) isolates were obtained from the clinical laboratory at the medical institute. Antibiotic susceptibility was tested by CLSI disk diffusion and ESBL confirmatory tests. MICs were determined using broth microdilution. Isoelectric focusing (IEF) was used to determine the pI values, inhibitor profiles, and cefotaxime (CTX) hydrolysis by the beta-lactamases. PCR and sequencing were performed using blaCTX-M and ISEcp1-specific primers, with DNA obtained from the clinical isolates. Conjugation experiments were done to determine the mobility of blaCTX-M. RESULTS: All five clinical isolates were resistant to CTX, and were positive for ESBL screening. IEF revealed multiple beta-lactamases produced by each isolate, including a beta-lactamase with a pI of 8.0 in Kp and ENT and a beta-lactamase with a pI of 9.0 in EC. Both beta-lactamases were inhibited by clavulanic acid and hydrolyzed CTX. PCR and sequence analysis identified blaCTX-M-14 in Kp and ENT and a blaCTX-M-15 in EC. Both blaCTX-M-14 and blaCTX-M-15 were preceded by ISEcp1 elements as revealed by partial sequence analysis of the upstream region of the blaCTX-M genes. blaCTX-M-15 was transferable but not blaCTX-M-14. CONCLUSION: This is the first report of CTX-M-14 in Kp and ENT isolates from Egypt, the Middle East and North Africa. More... »

PAGES

84

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2334-9-84

DOI

http://dx.doi.org/10.1186/1471-2334-9-84

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038311916

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19497111


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Conjugation, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Resistance, Multiple, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Egypt", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enterobacter cloacae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enterobacteriaceae Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Escherichia coli", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isoelectric Focusing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Klebsiella pneumoniae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microbial Sensitivity Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "beta-Lactamases", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Helwan University", 
          "id": "https://www.grid.ac/institutes/grid.412093.d", 
          "name": [
            "Department of Microbiology and Immunology, Faculty of Pharmacy Helwan University, Helwan, Egypt"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khalaf", 
        "givenName": "Noha G", 
        "id": "sg:person.01034643070.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034643070.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Heart Institute", 
          "id": "https://www.grid.ac/institutes/grid.489068.b", 
          "name": [
            "Clinical Microbiology department, National Heart Institute, Cairo, Egypt"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eletreby", 
        "givenName": "Mona M", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Creighton University", 
          "id": "https://www.grid.ac/institutes/grid.254748.8", 
          "name": [
            "Center for Research in Anti-Infectives and Biotechnology, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hanson", 
        "givenName": "Nancy D", 
        "id": "sg:person.01370453651.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370453651.63"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1128/jcm.42.12.5715-5721.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002730527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid0805.010346", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005562237"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/cmr.18.4.657-686.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007739875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.43.7.3309-3313.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016153268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijantimicag.2004.01.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016264261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.48.1.1-14.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016807294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkm316", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022693472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.47.7.2382-2383.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026664264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkg101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030851991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.30.6.951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031398658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijantimicag.2006.01.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032737229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/44.3.377", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033003366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.46.9.3045-3049.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033656859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.43.3.1037-1044.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034193244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.45.12.3355-3361.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036691750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.49.3.1150-1156.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042094154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.inf.0000168804.09875.95", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042146071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.inf.0000168804.09875.95", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042146071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.inf.0000168804.09875.95", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042146071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.47.9.2938-2945.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043464301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkf240", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044690916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijantimicag.2005.12.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048629404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.46.12.4038-4040.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062709934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2807/esm.11.07.00639-en", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077295158"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.42.3.596", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083233679"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-12", 
    "datePublishedReg": "2009-12-01", 
    "description": "BACKGROUND: A high rate of resistance to 3rd generation cephalosporins among Enterobacteriaceae isolates from Egypt has been previously reported. This study aims to characterize the resistance mechanism (s) to extended spectrum cephalosporins among resistant clinical isolates at a medical institute in Cairo, Egypt.\nMETHODS: Nonconsecutive Klebsiella pneumoniae (Kp), Enterobacter cloacae (ENT) and Escherichia coli (EC) isolates were obtained from the clinical laboratory at the medical institute. Antibiotic susceptibility was tested by CLSI disk diffusion and ESBL confirmatory tests. MICs were determined using broth microdilution. Isoelectric focusing (IEF) was used to determine the pI values, inhibitor profiles, and cefotaxime (CTX) hydrolysis by the beta-lactamases. PCR and sequencing were performed using blaCTX-M and ISEcp1-specific primers, with DNA obtained from the clinical isolates. Conjugation experiments were done to determine the mobility of blaCTX-M.\nRESULTS: All five clinical isolates were resistant to CTX, and were positive for ESBL screening. IEF revealed multiple beta-lactamases produced by each isolate, including a beta-lactamase with a pI of 8.0 in Kp and ENT and a beta-lactamase with a pI of 9.0 in EC. Both beta-lactamases were inhibited by clavulanic acid and hydrolyzed CTX. PCR and sequence analysis identified blaCTX-M-14 in Kp and ENT and a blaCTX-M-15 in EC. Both blaCTX-M-14 and blaCTX-M-15 were preceded by ISEcp1 elements as revealed by partial sequence analysis of the upstream region of the blaCTX-M genes. blaCTX-M-15 was transferable but not blaCTX-M-14.\nCONCLUSION: This is the first report of CTX-M-14 in Kp and ENT isolates from Egypt, the Middle East and North Africa.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2334-9-84", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024946", 
        "issn": [
          "1471-2334"
        ], 
        "name": "BMC Infectious Diseases", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "9"
      }
    ], 
    "name": "Characterization of CTX-M ESBLs in Enterobacter cloacae, Escherichia coli and Klebsiella pneumoniae clinical isolates from Cairo, Egypt", 
    "pagination": "84", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b680efe4e6480cabecd39b85aa9ae9a184dace25af39365a6dec87424a784dfc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19497111"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968551"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2334-9-84"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1038311916"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2334-9-84", 
      "https://app.dimensions.ai/details/publication/pub.1038311916"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000506.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2334-9-84"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-9-84'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-9-84'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-9-84'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-9-84'


 

This table displays all metadata directly associated to this object as RDF triples.

208 TRIPLES      21 PREDICATES      65 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2334-9-84 schema:about N1c5f5cfa594a4e04b3345c74d5bb3f6a
2 N554d3becd02b4a3fa0c86125beffad30
3 N5c5d21b98e45479d98e9e843fd77b236
4 N64ef7e4e3b60483ba52faf2e5a322a58
5 N69beb08f62a14b719249ce7bfc80bfab
6 N6b5e710122ef4aaf913f3354ceab4b5d
7 N6fb6de1eda934114acc0fecfa57f9f40
8 N820c4396f9ac43cdb07930e1244b2ec6
9 N88b52fd6175e42d1b1cb79adebfde92c
10 N8ce7ddd287b643ea89e301d88b82ce9e
11 N9059f55dce1940a0a5b8af5cb68e8d59
12 Nb23bee83b062467496d724d67ec25112
13 Nf1b482fb51c541569c674b0a179c5020
14 anzsrc-for:11
15 anzsrc-for:1108
16 schema:author Nf2d5dfd0c99e49beb2c35c367637c4d1
17 schema:citation https://doi.org/10.1016/j.ijantimicag.2004.01.010
18 https://doi.org/10.1016/j.ijantimicag.2005.12.007
19 https://doi.org/10.1016/j.ijantimicag.2006.01.007
20 https://doi.org/10.1093/jac/44.3.377
21 https://doi.org/10.1093/jac/dkf240
22 https://doi.org/10.1093/jac/dkg101
23 https://doi.org/10.1093/jac/dkm316
24 https://doi.org/10.1097/01.inf.0000168804.09875.95
25 https://doi.org/10.1128/aac.30.6.951
26 https://doi.org/10.1128/aac.42.3.596
27 https://doi.org/10.1128/aac.45.12.3355-3361.2001
28 https://doi.org/10.1128/aac.46.12.4038-4040.2002
29 https://doi.org/10.1128/aac.46.9.3045-3049.2002
30 https://doi.org/10.1128/aac.47.7.2382-2383.2003
31 https://doi.org/10.1128/aac.47.9.2938-2945.2003
32 https://doi.org/10.1128/aac.48.1.1-14.2004
33 https://doi.org/10.1128/aac.49.3.1150-1156.2005
34 https://doi.org/10.1128/cmr.18.4.657-686.2005
35 https://doi.org/10.1128/jcm.42.12.5715-5721.2004
36 https://doi.org/10.1128/jcm.43.3.1037-1044.2005
37 https://doi.org/10.1128/jcm.43.7.3309-3313.2005
38 https://doi.org/10.2807/esm.11.07.00639-en
39 https://doi.org/10.3201/eid0805.010346
40 schema:datePublished 2009-12
41 schema:datePublishedReg 2009-12-01
42 schema:description BACKGROUND: A high rate of resistance to 3rd generation cephalosporins among Enterobacteriaceae isolates from Egypt has been previously reported. This study aims to characterize the resistance mechanism (s) to extended spectrum cephalosporins among resistant clinical isolates at a medical institute in Cairo, Egypt. METHODS: Nonconsecutive Klebsiella pneumoniae (Kp), Enterobacter cloacae (ENT) and Escherichia coli (EC) isolates were obtained from the clinical laboratory at the medical institute. Antibiotic susceptibility was tested by CLSI disk diffusion and ESBL confirmatory tests. MICs were determined using broth microdilution. Isoelectric focusing (IEF) was used to determine the pI values, inhibitor profiles, and cefotaxime (CTX) hydrolysis by the beta-lactamases. PCR and sequencing were performed using blaCTX-M and ISEcp1-specific primers, with DNA obtained from the clinical isolates. Conjugation experiments were done to determine the mobility of blaCTX-M. RESULTS: All five clinical isolates were resistant to CTX, and were positive for ESBL screening. IEF revealed multiple beta-lactamases produced by each isolate, including a beta-lactamase with a pI of 8.0 in Kp and ENT and a beta-lactamase with a pI of 9.0 in EC. Both beta-lactamases were inhibited by clavulanic acid and hydrolyzed CTX. PCR and sequence analysis identified blaCTX-M-14 in Kp and ENT and a blaCTX-M-15 in EC. Both blaCTX-M-14 and blaCTX-M-15 were preceded by ISEcp1 elements as revealed by partial sequence analysis of the upstream region of the blaCTX-M genes. blaCTX-M-15 was transferable but not blaCTX-M-14. CONCLUSION: This is the first report of CTX-M-14 in Kp and ENT isolates from Egypt, the Middle East and North Africa.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree true
46 schema:isPartOf N22957d1ecdaf425e97117c79d02ec115
47 N60de24a7c45841fb9fb24acd8e191926
48 sg:journal.1024946
49 schema:name Characterization of CTX-M ESBLs in Enterobacter cloacae, Escherichia coli and Klebsiella pneumoniae clinical isolates from Cairo, Egypt
50 schema:pagination 84
51 schema:productId N1921e208f6724ab7b2476778bcbd391c
52 N49876adc926b4d47bddeacefed49b5d3
53 N7c37166791094ee0a6cc35712bcc132b
54 N93f2633e69854b818b2a9a409c9fbb8f
55 Nc2b29b5af7b44e09b22cc4034f56df11
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038311916
57 https://doi.org/10.1186/1471-2334-9-84
58 schema:sdDatePublished 2019-04-11T01:58
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher N8ca524283d6745f6bf6aa313666ca62f
61 schema:url http://link.springer.com/10.1186%2F1471-2334-9-84
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N1921e208f6724ab7b2476778bcbd391c schema:name pubmed_id
66 schema:value 19497111
67 rdf:type schema:PropertyValue
68 N1c5f5cfa594a4e04b3345c74d5bb3f6a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Enterobacter cloacae
70 rdf:type schema:DefinedTerm
71 N22957d1ecdaf425e97117c79d02ec115 schema:issueNumber 1
72 rdf:type schema:PublicationIssue
73 N28e3e6683986412e9c0dfc1ee2981751 rdf:first sg:person.01370453651.63
74 rdf:rest rdf:nil
75 N49876adc926b4d47bddeacefed49b5d3 schema:name nlm_unique_id
76 schema:value 100968551
77 rdf:type schema:PropertyValue
78 N554d3becd02b4a3fa0c86125beffad30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Egypt
80 rdf:type schema:DefinedTerm
81 N5c5d21b98e45479d98e9e843fd77b236 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Conjugation, Genetic
83 rdf:type schema:DefinedTerm
84 N60de24a7c45841fb9fb24acd8e191926 schema:volumeNumber 9
85 rdf:type schema:PublicationVolume
86 N64ef7e4e3b60483ba52faf2e5a322a58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Klebsiella pneumoniae
88 rdf:type schema:DefinedTerm
89 N66c0aadd956f4372bc95ff360dc3b12f schema:affiliation https://www.grid.ac/institutes/grid.489068.b
90 schema:familyName Eletreby
91 schema:givenName Mona M
92 rdf:type schema:Person
93 N69beb08f62a14b719249ce7bfc80bfab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Genes, Bacterial
95 rdf:type schema:DefinedTerm
96 N6b5e710122ef4aaf913f3354ceab4b5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Drug Resistance, Multiple, Bacterial
98 rdf:type schema:DefinedTerm
99 N6fb6de1eda934114acc0fecfa57f9f40 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Escherichia coli
101 rdf:type schema:DefinedTerm
102 N7c37166791094ee0a6cc35712bcc132b schema:name doi
103 schema:value 10.1186/1471-2334-9-84
104 rdf:type schema:PropertyValue
105 N820c4396f9ac43cdb07930e1244b2ec6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Microbial Sensitivity Tests
107 rdf:type schema:DefinedTerm
108 N88b52fd6175e42d1b1cb79adebfde92c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name beta-Lactamases
110 rdf:type schema:DefinedTerm
111 N8ca524283d6745f6bf6aa313666ca62f schema:name Springer Nature - SN SciGraph project
112 rdf:type schema:Organization
113 N8ce7ddd287b643ea89e301d88b82ce9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Isoelectric Focusing
115 rdf:type schema:DefinedTerm
116 N9059f55dce1940a0a5b8af5cb68e8d59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Humans
118 rdf:type schema:DefinedTerm
119 N93f2633e69854b818b2a9a409c9fbb8f schema:name dimensions_id
120 schema:value pub.1038311916
121 rdf:type schema:PropertyValue
122 Nb23bee83b062467496d724d67ec25112 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Enterobacteriaceae Infections
124 rdf:type schema:DefinedTerm
125 Nc2b29b5af7b44e09b22cc4034f56df11 schema:name readcube_id
126 schema:value b680efe4e6480cabecd39b85aa9ae9a184dace25af39365a6dec87424a784dfc
127 rdf:type schema:PropertyValue
128 Nf1b482fb51c541569c674b0a179c5020 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Anti-Bacterial Agents
130 rdf:type schema:DefinedTerm
131 Nf2d5dfd0c99e49beb2c35c367637c4d1 rdf:first sg:person.01034643070.09
132 rdf:rest Nfc78df396ccc4450a3bb59759d7da465
133 Nfc78df396ccc4450a3bb59759d7da465 rdf:first N66c0aadd956f4372bc95ff360dc3b12f
134 rdf:rest N28e3e6683986412e9c0dfc1ee2981751
135 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
136 schema:name Medical and Health Sciences
137 rdf:type schema:DefinedTerm
138 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
139 schema:name Medical Microbiology
140 rdf:type schema:DefinedTerm
141 sg:journal.1024946 schema:issn 1471-2334
142 schema:name BMC Infectious Diseases
143 rdf:type schema:Periodical
144 sg:person.01034643070.09 schema:affiliation https://www.grid.ac/institutes/grid.412093.d
145 schema:familyName Khalaf
146 schema:givenName Noha G
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034643070.09
148 rdf:type schema:Person
149 sg:person.01370453651.63 schema:affiliation https://www.grid.ac/institutes/grid.254748.8
150 schema:familyName Hanson
151 schema:givenName Nancy D
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370453651.63
153 rdf:type schema:Person
154 https://doi.org/10.1016/j.ijantimicag.2004.01.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016264261
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1016/j.ijantimicag.2005.12.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048629404
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/j.ijantimicag.2006.01.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032737229
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1093/jac/44.3.377 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033003366
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1093/jac/dkf240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044690916
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1093/jac/dkg101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030851991
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1093/jac/dkm316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022693472
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1097/01.inf.0000168804.09875.95 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042146071
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1128/aac.30.6.951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031398658
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1128/aac.42.3.596 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083233679
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1128/aac.45.12.3355-3361.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036691750
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1128/aac.46.12.4038-4040.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062709934
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1128/aac.46.9.3045-3049.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033656859
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1128/aac.47.7.2382-2383.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026664264
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1128/aac.47.9.2938-2945.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043464301
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1128/aac.48.1.1-14.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016807294
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1128/aac.49.3.1150-1156.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042094154
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1128/cmr.18.4.657-686.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007739875
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1128/jcm.42.12.5715-5721.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002730527
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1128/jcm.43.3.1037-1044.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034193244
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1128/jcm.43.7.3309-3313.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016153268
195 rdf:type schema:CreativeWork
196 https://doi.org/10.2807/esm.11.07.00639-en schema:sameAs https://app.dimensions.ai/details/publication/pub.1077295158
197 rdf:type schema:CreativeWork
198 https://doi.org/10.3201/eid0805.010346 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005562237
199 rdf:type schema:CreativeWork
200 https://www.grid.ac/institutes/grid.254748.8 schema:alternateName Creighton University
201 schema:name Center for Research in Anti-Infectives and Biotechnology, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA
202 rdf:type schema:Organization
203 https://www.grid.ac/institutes/grid.412093.d schema:alternateName Helwan University
204 schema:name Department of Microbiology and Immunology, Faculty of Pharmacy Helwan University, Helwan, Egypt
205 rdf:type schema:Organization
206 https://www.grid.ac/institutes/grid.489068.b schema:alternateName National Heart Institute
207 schema:name Clinical Microbiology department, National Heart Institute, Cairo, Egypt
208 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...