Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-12

AUTHORS

Asgeir Johannessen, Ezra Naman, Bernard J Ngowi, Leiv Sandvik, Mecky I Matee, Henry E Aglen, Svein G Gundersen, Johan N Bruun

ABSTRACT

BACKGROUND: Studies of antiretroviral therapy (ART) programs in Africa have shown high initial mortality. Factors contributing to this high mortality are poorly described. The aim of the present study was to assess mortality and to identify predictors of mortality in HIV-infected patients starting ART in a rural hospital in Tanzania. METHODS: This was a cohort study of 320 treatment-naïve adults who started ART between October 2003 and November 2006. Reliable CD4 cell counts were not available, thus ART initiation was based on clinical criteria in accordance with WHO and Tanzanian guidelines. Kaplan-Meier models were used to estimate mortality and Cox proportional hazards models to identify predictors of mortality. RESULTS: Patients were followed for a median of 10.9 months (IQR 2.9-19.5). Overall, 95 patients died, among whom 59 died within 3 months of starting ART. Estimated mortality was 19.2, 29.0 and 40.7% at 3, 12 and 36 months, respectively. Independent predictors of mortality were severe anemia (hemoglobin <8 g/dL; adjusted hazard ratio [AHR] 9.20; 95% CI 2.05-41.3), moderate anemia (hemoglobin 8-9.9 g/dL; AHR 7.50; 95% CI 1.77-31.9), thrombocytopenia (platelet count <150 x 109/L; AHR 2.30; 95% CI 1.33-3.99) and severe malnutrition (body mass index <16 kg/m2; AHR 2.12; 95% CI 1.06-4.24). Estimated one year mortality was 55.2% in patients with severe anemia, compared to 3.7% in patients without anemia (P < 0.001). CONCLUSION: Mortality was found to be high, with the majority of deaths occurring within 3 months of starting ART. Anemia, thrombocytopenia and severe malnutrition were strong independent predictors of mortality. A prognostic model based on hemoglobin level appears to be a useful tool for initial risk assessment in resource-limited settings. More... »

PAGES

52

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2334-8-52

DOI

http://dx.doi.org/10.1186/1471-2334-8-52

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037242311

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18430196


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anemia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Retroviral Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hospitals, Rural", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kaplan-Meier Estimate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malnutrition", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tanzania", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thrombocytopenia", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Oslo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.55325.34", 
          "name": [
            "Department of Infectious Diseases, Ulleval University Hospital, Oslo, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Johannessen", 
        "givenName": "Asgeir", 
        "id": "sg:person.0646757462.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646757462.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Haydom Lutheran Hospital", 
          "id": "https://www.grid.ac/institutes/grid.461293.b", 
          "name": [
            "HIV Care and Treatment Centre, Haydom Lutheran Hospital, Mbulu, Tanzania"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Naman", 
        "givenName": "Ezra", 
        "id": "sg:person.0724314016.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724314016.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bergen", 
          "id": "https://www.grid.ac/institutes/grid.7914.b", 
          "name": [
            "HIV Care and Treatment Centre, Haydom Lutheran Hospital, Mbulu, Tanzania", 
            "Centre for International Health, University of Bergen, Bergen, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ngowi", 
        "givenName": "Bernard J", 
        "id": "sg:person.01073312447.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073312447.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Oslo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.55325.34", 
          "name": [
            "Centre for Clinical Research, Ulleval University Hospital, Oslo, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sandvik", 
        "givenName": "Leiv", 
        "id": "sg:person.01260036271.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260036271.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Muhimbili University of Health and Allied Sciences", 
          "id": "https://www.grid.ac/institutes/grid.25867.3e", 
          "name": [
            "Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matee", 
        "givenName": "Mecky I", 
        "id": "sg:person.01271046131.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271046131.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Research Unit, Sorlandet Hospital HF, University of Agder, Kristiansand, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aglen", 
        "givenName": "Henry E", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Agder", 
          "id": "https://www.grid.ac/institutes/grid.23048.3d", 
          "name": [
            "Research Unit, Sorlandet Hospital HF, University of Agder, Kristiansand, Norway", 
            "Faculty for Health and Sports, University of Agder, Kristiansand, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gundersen", 
        "givenName": "Svein G", 
        "id": "sg:person.010304600474.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010304600474.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Oslo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.55325.34", 
          "name": [
            "Department of Infectious Diseases, Ulleval University Hospital, Oslo, Norway"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bruun", 
        "givenName": "Johan N", 
        "id": "sg:person.01213663062.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213663062.36"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.2310/6650.2001.33967", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003690389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2458-7-103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007356265", 
          "https://doi.org/10.1186/1471-2458-7-103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aids.0000226959.87471.01", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010099240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aids.0000226959.87471.01", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010099240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aids.0000226959.87471.01", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010099240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32801086b0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013445372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32801086b0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013445372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32801086b0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013445372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200404090-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014887260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200404090-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014887260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aids.0000194802.89540.e1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015300302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aids.0000194802.89540.e1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015300302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aids.0000194802.89540.e1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015300302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-200201010-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016739003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(02)09411-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020490022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e31802bf109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024138394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e31802bf109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024138394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qai.0b013e31802bf109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024138394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/507095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024904013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(06)68580-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026230434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa051908", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032723537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000134759.01684.27", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032966544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000134759.01684.27", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032966544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1468-1293.2006.00383.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036334609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000026514.98625.8f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036347155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000026514.98625.8f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036347155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000159668.80207.5b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038748224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000159668.80207.5b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038748224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.qai.0000159668.80207.5b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038748224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199805010-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039179609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199805010-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039179609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(98)03201-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039692940"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/09537100120093956", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042628563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-199905280-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047096954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-199905280-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047096954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/coh.0b013e32835b8123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048217292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/coh.0b013e32835b8123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048217292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1099-0844(199912)17:4<279::aid-cbf833>3.0.co;2-j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052168449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.296.7.782", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052189815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/431199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052345699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/431199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052345699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199809010-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053528564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199809010-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053528564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199704010-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060296265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199704010-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060296265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00042560-199704010-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060296265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-130-6-199903160-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073703208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075098025", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076978911", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077043051", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082956107", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083191064", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-12", 
    "datePublishedReg": "2008-12-01", 
    "description": "BACKGROUND: Studies of antiretroviral therapy (ART) programs in Africa have shown high initial mortality. Factors contributing to this high mortality are poorly described. The aim of the present study was to assess mortality and to identify predictors of mortality in HIV-infected patients starting ART in a rural hospital in Tanzania.\nMETHODS: This was a cohort study of 320 treatment-na\u00efve adults who started ART between October 2003 and November 2006. Reliable CD4 cell counts were not available, thus ART initiation was based on clinical criteria in accordance with WHO and Tanzanian guidelines. Kaplan-Meier models were used to estimate mortality and Cox proportional hazards models to identify predictors of mortality.\nRESULTS: Patients were followed for a median of 10.9 months (IQR 2.9-19.5). Overall, 95 patients died, among whom 59 died within 3 months of starting ART. Estimated mortality was 19.2, 29.0 and 40.7% at 3, 12 and 36 months, respectively. Independent predictors of mortality were severe anemia (hemoglobin <8 g/dL; adjusted hazard ratio [AHR] 9.20; 95% CI 2.05-41.3), moderate anemia (hemoglobin 8-9.9 g/dL; AHR 7.50; 95% CI 1.77-31.9), thrombocytopenia (platelet count <150 x 109/L; AHR 2.30; 95% CI 1.33-3.99) and severe malnutrition (body mass index <16 kg/m2; AHR 2.12; 95% CI 1.06-4.24). Estimated one year mortality was 55.2% in patients with severe anemia, compared to 3.7% in patients without anemia (P < 0.001).\nCONCLUSION: Mortality was found to be high, with the majority of deaths occurring within 3 months of starting ART. Anemia, thrombocytopenia and severe malnutrition were strong independent predictors of mortality. A prognostic model based on hemoglobin level appears to be a useful tool for initial risk assessment in resource-limited settings.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2334-8-52", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024946", 
        "issn": [
          "1471-2334"
        ], 
        "name": "BMC Infectious Diseases", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania", 
    "pagination": "52", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b168dc77b976849c8cdd8bfdac1932ba51c3ebafd38dffa8a6c0962f9480003f"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18430196"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968551"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2334-8-52"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037242311"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2334-8-52", 
      "https://app.dimensions.ai/details/publication/pub.1037242311"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000506.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2334-8-52"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-8-52'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-8-52'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-8-52'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-8-52'


 

This table displays all metadata directly associated to this object as RDF triples.

301 TRIPLES      21 PREDICATES      80 URIs      40 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2334-8-52 schema:about N0a671460648248f7adb719ad19c62815
2 N0a88211f708943b699eb8c2f4b815a59
3 N136ceb11955441ff95b0e92e9987890c
4 N157a477e575c435e82d8d28dac0624c0
5 N3cfa7cbf83784ae1a255f5146c6be97e
6 N3de6fdef195047f383372195ac44b459
7 N46e522fd84a54a6fa097e9423832c23c
8 N59d822b40347404bb8c9968583dad641
9 N78e1870c8ca5473791d1ffea3953f552
10 N828f95ffc4144ec489ac0fdd19ac347c
11 N9768776806754bcaa377d30355f24205
12 Nbb65064ccc46498fabeb48ecb1d8a435
13 Nbbdff37a46b646e084d41d1afe3a8f7a
14 Nc3600b102bea45d5abf412beda8c5567
15 Nca4bec8173e34c2f9e09d83544d15a97
16 Nd0dad84340ea4d6c97b5a37c5c1563b2
17 Nd513e2ba31b047f4bf67277294749de0
18 Ndaf65a147e0944f29267f3b1cbfc8513
19 Nf45f75a90e584ca8be25a44f9083a31d
20 anzsrc-for:11
21 anzsrc-for:1103
22 schema:author N24dcb80749fb4ae0a5e738a5d30c9f8b
23 schema:citation sg:pub.10.1186/1471-2458-7-103
24 https://app.dimensions.ai/details/publication/pub.1075098025
25 https://app.dimensions.ai/details/publication/pub.1076978911
26 https://app.dimensions.ai/details/publication/pub.1077043051
27 https://app.dimensions.ai/details/publication/pub.1082956107
28 https://app.dimensions.ai/details/publication/pub.1083191064
29 https://doi.org/10.1001/jama.296.7.782
30 https://doi.org/10.1002/(sici)1099-0844(199912)17:4<279::aid-cbf833>3.0.co;2-j
31 https://doi.org/10.1016/s0140-6736(02)09411-4
32 https://doi.org/10.1016/s0140-6736(06)68580-2
33 https://doi.org/10.1016/s0140-6736(98)03201-2
34 https://doi.org/10.1056/nejmoa051908
35 https://doi.org/10.1080/09537100120093956
36 https://doi.org/10.1086/431199
37 https://doi.org/10.1086/507095
38 https://doi.org/10.1097/00002030-199905280-00010
39 https://doi.org/10.1097/00002030-200404090-00006
40 https://doi.org/10.1097/00042560-199704010-00011
41 https://doi.org/10.1097/00042560-199805010-00012
42 https://doi.org/10.1097/00042560-199809010-00004
43 https://doi.org/10.1097/00042560-200201010-00007
44 https://doi.org/10.1097/01.aids.0000194802.89540.e1
45 https://doi.org/10.1097/01.aids.0000226959.87471.01
46 https://doi.org/10.1097/01.qai.0000026514.98625.8f
47 https://doi.org/10.1097/01.qai.0000134759.01684.27
48 https://doi.org/10.1097/01.qai.0000159668.80207.5b
49 https://doi.org/10.1097/coh.0b013e32835b8123
50 https://doi.org/10.1097/qad.0b013e32801086b0
51 https://doi.org/10.1097/qai.0b013e31802bf109
52 https://doi.org/10.1111/j.1468-1293.2006.00383.x
53 https://doi.org/10.2310/6650.2001.33967
54 https://doi.org/10.7326/0003-4819-130-6-199903160-00016
55 schema:datePublished 2008-12
56 schema:datePublishedReg 2008-12-01
57 schema:description BACKGROUND: Studies of antiretroviral therapy (ART) programs in Africa have shown high initial mortality. Factors contributing to this high mortality are poorly described. The aim of the present study was to assess mortality and to identify predictors of mortality in HIV-infected patients starting ART in a rural hospital in Tanzania. METHODS: This was a cohort study of 320 treatment-naïve adults who started ART between October 2003 and November 2006. Reliable CD4 cell counts were not available, thus ART initiation was based on clinical criteria in accordance with WHO and Tanzanian guidelines. Kaplan-Meier models were used to estimate mortality and Cox proportional hazards models to identify predictors of mortality. RESULTS: Patients were followed for a median of 10.9 months (IQR 2.9-19.5). Overall, 95 patients died, among whom 59 died within 3 months of starting ART. Estimated mortality was 19.2, 29.0 and 40.7% at 3, 12 and 36 months, respectively. Independent predictors of mortality were severe anemia (hemoglobin <8 g/dL; adjusted hazard ratio [AHR] 9.20; 95% CI 2.05-41.3), moderate anemia (hemoglobin 8-9.9 g/dL; AHR 7.50; 95% CI 1.77-31.9), thrombocytopenia (platelet count <150 x 109/L; AHR 2.30; 95% CI 1.33-3.99) and severe malnutrition (body mass index <16 kg/m2; AHR 2.12; 95% CI 1.06-4.24). Estimated one year mortality was 55.2% in patients with severe anemia, compared to 3.7% in patients without anemia (P < 0.001). CONCLUSION: Mortality was found to be high, with the majority of deaths occurring within 3 months of starting ART. Anemia, thrombocytopenia and severe malnutrition were strong independent predictors of mortality. A prognostic model based on hemoglobin level appears to be a useful tool for initial risk assessment in resource-limited settings.
58 schema:genre research_article
59 schema:inLanguage en
60 schema:isAccessibleForFree true
61 schema:isPartOf N789a43e9b0c14baab7db94953a6c6dcc
62 Nd10514a33f9c4195a6f07a4c58595af2
63 sg:journal.1024946
64 schema:name Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania
65 schema:pagination 52
66 schema:productId N2fff45ed8bd7491b82825bab718ddd65
67 N8d55bbe0d89e46d9a3cf4f5515d4822d
68 N99dedd563b4f4581a782605f75a023b9
69 Nc34e1b9b224d427db05ef71e0c091796
70 Ndf8d1d9c1783488f839ffdc4a2f53c7e
71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037242311
72 https://doi.org/10.1186/1471-2334-8-52
73 schema:sdDatePublished 2019-04-10T17:30
74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
75 schema:sdPublisher N460b2fcacb6442328f859e384115d5de
76 schema:url http://link.springer.com/10.1186%2F1471-2334-8-52
77 sgo:license sg:explorer/license/
78 sgo:sdDataset articles
79 rdf:type schema:ScholarlyArticle
80 N0a671460648248f7adb719ad19c62815 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Prognosis
82 rdf:type schema:DefinedTerm
83 N0a88211f708943b699eb8c2f4b815a59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Tanzania
85 rdf:type schema:DefinedTerm
86 N136ceb11955441ff95b0e92e9987890c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Thrombocytopenia
88 rdf:type schema:DefinedTerm
89 N157a477e575c435e82d8d28dac0624c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name HIV Infections
91 rdf:type schema:DefinedTerm
92 N176a3cfadbb04a45adcc50b9a645f0db rdf:first sg:person.01073312447.57
93 rdf:rest N2844787ac9de409589e2c688b4faa446
94 N24dcb80749fb4ae0a5e738a5d30c9f8b rdf:first sg:person.0646757462.58
95 rdf:rest Nb655dbe80b894da69067bf3690ba1874
96 N2844787ac9de409589e2c688b4faa446 rdf:first sg:person.01260036271.02
97 rdf:rest N35231aa4e65a4aa4a6282bedc57ba266
98 N2fff45ed8bd7491b82825bab718ddd65 schema:name dimensions_id
99 schema:value pub.1037242311
100 rdf:type schema:PropertyValue
101 N35231aa4e65a4aa4a6282bedc57ba266 rdf:first sg:person.01271046131.83
102 rdf:rest N3aedd8e3880b498fac5955ea42a7c01e
103 N3aedd8e3880b498fac5955ea42a7c01e rdf:first Nc223d4c49b4e486f8322c49dea405ee9
104 rdf:rest N763dfa65389249389bee7f3296461c34
105 N3cfa7cbf83784ae1a255f5146c6be97e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Malnutrition
107 rdf:type schema:DefinedTerm
108 N3de6fdef195047f383372195ac44b459 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Risk Factors
110 rdf:type schema:DefinedTerm
111 N460b2fcacb6442328f859e384115d5de schema:name Springer Nature - SN SciGraph project
112 rdf:type schema:Organization
113 N46e522fd84a54a6fa097e9423832c23c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Cohort Studies
115 rdf:type schema:DefinedTerm
116 N59d822b40347404bb8c9968583dad641 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Female
118 rdf:type schema:DefinedTerm
119 N763dfa65389249389bee7f3296461c34 rdf:first sg:person.010304600474.08
120 rdf:rest N814e682a127442c6a4ddd33d144aa091
121 N789a43e9b0c14baab7db94953a6c6dcc schema:issueNumber 1
122 rdf:type schema:PublicationIssue
123 N78e1870c8ca5473791d1ffea3953f552 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Middle Aged
125 rdf:type schema:DefinedTerm
126 N814e682a127442c6a4ddd33d144aa091 rdf:first sg:person.01213663062.36
127 rdf:rest rdf:nil
128 N828f95ffc4144ec489ac0fdd19ac347c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Anemia
130 rdf:type schema:DefinedTerm
131 N8d55bbe0d89e46d9a3cf4f5515d4822d schema:name doi
132 schema:value 10.1186/1471-2334-8-52
133 rdf:type schema:PropertyValue
134 N9768776806754bcaa377d30355f24205 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Follow-Up Studies
136 rdf:type schema:DefinedTerm
137 N99dedd563b4f4581a782605f75a023b9 schema:name nlm_unique_id
138 schema:value 100968551
139 rdf:type schema:PropertyValue
140 Nb655dbe80b894da69067bf3690ba1874 rdf:first sg:person.0724314016.93
141 rdf:rest N176a3cfadbb04a45adcc50b9a645f0db
142 Nbb65064ccc46498fabeb48ecb1d8a435 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Adult
144 rdf:type schema:DefinedTerm
145 Nbbdff37a46b646e084d41d1afe3a8f7a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Humans
147 rdf:type schema:DefinedTerm
148 Nc223d4c49b4e486f8322c49dea405ee9 schema:affiliation Nccaaee24526a4985b4d6181d7cbbcdd3
149 schema:familyName Aglen
150 schema:givenName Henry E
151 rdf:type schema:Person
152 Nc34e1b9b224d427db05ef71e0c091796 schema:name pubmed_id
153 schema:value 18430196
154 rdf:type schema:PropertyValue
155 Nc3600b102bea45d5abf412beda8c5567 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Hospitals, Rural
157 rdf:type schema:DefinedTerm
158 Nca4bec8173e34c2f9e09d83544d15a97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Kaplan-Meier Estimate
160 rdf:type schema:DefinedTerm
161 Nccaaee24526a4985b4d6181d7cbbcdd3 schema:name Research Unit, Sorlandet Hospital HF, University of Agder, Kristiansand, Norway
162 rdf:type schema:Organization
163 Nd0dad84340ea4d6c97b5a37c5c1563b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Adolescent
165 rdf:type schema:DefinedTerm
166 Nd10514a33f9c4195a6f07a4c58595af2 schema:volumeNumber 8
167 rdf:type schema:PublicationVolume
168 Nd513e2ba31b047f4bf67277294749de0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Male
170 rdf:type schema:DefinedTerm
171 Ndaf65a147e0944f29267f3b1cbfc8513 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Anti-Retroviral Agents
173 rdf:type schema:DefinedTerm
174 Ndf8d1d9c1783488f839ffdc4a2f53c7e schema:name readcube_id
175 schema:value b168dc77b976849c8cdd8bfdac1932ba51c3ebafd38dffa8a6c0962f9480003f
176 rdf:type schema:PropertyValue
177 Nf45f75a90e584ca8be25a44f9083a31d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Survival Analysis
179 rdf:type schema:DefinedTerm
180 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
181 schema:name Medical and Health Sciences
182 rdf:type schema:DefinedTerm
183 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
184 schema:name Clinical Sciences
185 rdf:type schema:DefinedTerm
186 sg:journal.1024946 schema:issn 1471-2334
187 schema:name BMC Infectious Diseases
188 rdf:type schema:Periodical
189 sg:person.010304600474.08 schema:affiliation https://www.grid.ac/institutes/grid.23048.3d
190 schema:familyName Gundersen
191 schema:givenName Svein G
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010304600474.08
193 rdf:type schema:Person
194 sg:person.01073312447.57 schema:affiliation https://www.grid.ac/institutes/grid.7914.b
195 schema:familyName Ngowi
196 schema:givenName Bernard J
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073312447.57
198 rdf:type schema:Person
199 sg:person.01213663062.36 schema:affiliation https://www.grid.ac/institutes/grid.55325.34
200 schema:familyName Bruun
201 schema:givenName Johan N
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213663062.36
203 rdf:type schema:Person
204 sg:person.01260036271.02 schema:affiliation https://www.grid.ac/institutes/grid.55325.34
205 schema:familyName Sandvik
206 schema:givenName Leiv
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260036271.02
208 rdf:type schema:Person
209 sg:person.01271046131.83 schema:affiliation https://www.grid.ac/institutes/grid.25867.3e
210 schema:familyName Matee
211 schema:givenName Mecky I
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271046131.83
213 rdf:type schema:Person
214 sg:person.0646757462.58 schema:affiliation https://www.grid.ac/institutes/grid.55325.34
215 schema:familyName Johannessen
216 schema:givenName Asgeir
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646757462.58
218 rdf:type schema:Person
219 sg:person.0724314016.93 schema:affiliation https://www.grid.ac/institutes/grid.461293.b
220 schema:familyName Naman
221 schema:givenName Ezra
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724314016.93
223 rdf:type schema:Person
224 sg:pub.10.1186/1471-2458-7-103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007356265
225 https://doi.org/10.1186/1471-2458-7-103
226 rdf:type schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1075098025 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1076978911 schema:CreativeWork
229 https://app.dimensions.ai/details/publication/pub.1077043051 schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1082956107 schema:CreativeWork
231 https://app.dimensions.ai/details/publication/pub.1083191064 schema:CreativeWork
232 https://doi.org/10.1001/jama.296.7.782 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052189815
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/(sici)1099-0844(199912)17:4<279::aid-cbf833>3.0.co;2-j schema:sameAs https://app.dimensions.ai/details/publication/pub.1052168449
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/s0140-6736(02)09411-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020490022
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/s0140-6736(06)68580-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026230434
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/s0140-6736(98)03201-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039692940
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1056/nejmoa051908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032723537
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1080/09537100120093956 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042628563
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1086/431199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052345699
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1086/507095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024904013
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1097/00002030-199905280-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047096954
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1097/00002030-200404090-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014887260
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1097/00042560-199704010-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060296265
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1097/00042560-199805010-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039179609
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1097/00042560-199809010-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053528564
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/00042560-200201010-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016739003
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1097/01.aids.0000194802.89540.e1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015300302
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1097/01.aids.0000226959.87471.01 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010099240
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1097/01.qai.0000026514.98625.8f schema:sameAs https://app.dimensions.ai/details/publication/pub.1036347155
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1097/01.qai.0000134759.01684.27 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032966544
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1097/01.qai.0000159668.80207.5b schema:sameAs https://app.dimensions.ai/details/publication/pub.1038748224
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1097/coh.0b013e32835b8123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048217292
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1097/qad.0b013e32801086b0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013445372
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1097/qai.0b013e31802bf109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024138394
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1111/j.1468-1293.2006.00383.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036334609
279 rdf:type schema:CreativeWork
280 https://doi.org/10.2310/6650.2001.33967 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003690389
281 rdf:type schema:CreativeWork
282 https://doi.org/10.7326/0003-4819-130-6-199903160-00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073703208
283 rdf:type schema:CreativeWork
284 https://www.grid.ac/institutes/grid.23048.3d schema:alternateName University of Agder
285 schema:name Faculty for Health and Sports, University of Agder, Kristiansand, Norway
286 Research Unit, Sorlandet Hospital HF, University of Agder, Kristiansand, Norway
287 rdf:type schema:Organization
288 https://www.grid.ac/institutes/grid.25867.3e schema:alternateName Muhimbili University of Health and Allied Sciences
289 schema:name Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
290 rdf:type schema:Organization
291 https://www.grid.ac/institutes/grid.461293.b schema:alternateName Haydom Lutheran Hospital
292 schema:name HIV Care and Treatment Centre, Haydom Lutheran Hospital, Mbulu, Tanzania
293 rdf:type schema:Organization
294 https://www.grid.ac/institutes/grid.55325.34 schema:alternateName Oslo University Hospital
295 schema:name Centre for Clinical Research, Ulleval University Hospital, Oslo, Norway
296 Department of Infectious Diseases, Ulleval University Hospital, Oslo, Norway
297 rdf:type schema:Organization
298 https://www.grid.ac/institutes/grid.7914.b schema:alternateName University of Bergen
299 schema:name Centre for International Health, University of Bergen, Bergen, Norway
300 HIV Care and Treatment Centre, Haydom Lutheran Hospital, Mbulu, Tanzania
301 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...