Effect of prolonged HAART on oral colonization with Candidaand candidiasis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-01-20

AUTHORS

Yun-Liang Yang, Hsiu-Jung Lo, Chien-Ching Hung, Yichun Li

ABSTRACT

BackgroundProgressive cell-mediated immunodeficiency with decrease of CD4+ lymphocyte count to less than or equal to 200 cells/mm3 is a major risk factor for colonization with Candida species and development of candidiasis. Oropharyngeal candidiasis may occur in up to 90% of human immunodeficiency virus (HIV)-infected patients during the course of the disease. This study is to determine the effect of prolonged highly active antiretroviral therapy (HAART) on oropharyngeal colonization with Candida species and oral candidiasis.MethodsA prospective, longitudinal follow-up study in HIV-infected patients receiving HAART.ResultsThe mean CD4+ count increased from 232.5 to 316 cells/mm3 and the proportion of patients whose CD4+ count less than 200 cells/mm3 decreased from 50.0% to 28.9% (p = 0.0003) in patients receiving HAART for at least 2 years. The prevalence of oral candidiasis decreased from 10.6% to 2.1% (p = 0.004). The decrease in Candida colonization was less impressive, falling from 57.8% to 46.5 % (p = 0.06). Of the 142 patients enrolled in at least two surveys, 48 (33.8%) remained colonized with Candida and 42 (29.6%) remained negative. In the remaining 52 patients, 34 switched from culture positive to negative, and an increase in CD4+ lymphocytes was noted in 91.2% of them. Among the 18 patients who switched from culture negative to positive, 61.1% also demonstrated an increase in CD4+ lymphocyte count (p = 0.01).ConclusionThese findings indicate that HAART is highly effective in decreasing oral candidiasis in association with a rise in CD4+ lymphocyte counts, but only marginally effective in eliminating Candida from the oropharynx. More... »

PAGES

8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2334-6-8

DOI

http://dx.doi.org/10.1186/1471-2334-6-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030185655

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16423306


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "AIDS-Related Opportunistic Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-HIV Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antifungal Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antiretroviral Therapy, Highly Active", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "CD4 Lymphocyte Count", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Candida", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Candidiasis, Oral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Administration Schedule", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Longitudinal Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oropharynx", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, ROC, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.260539.b", 
          "name": [
            "Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, ROC, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yang", 
        "givenName": "Yun-Liang", 
        "id": "sg:person.01173034452.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173034452.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Clinical Research, National Health Research Institutes, Miaoli, ROC, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.59784.37", 
          "name": [
            "Division of Clinical Research, National Health Research Institutes, Miaoli, ROC, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lo", 
        "givenName": "Hsiu-Jung", 
        "id": "sg:person.01062447152.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062447152.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, ROC, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.412094.a", 
          "name": [
            "Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, ROC, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hung", 
        "givenName": "Chien-Ching", 
        "id": "sg:person.01312660244.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312660244.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, ROC, Taiwan", 
          "id": "http://www.grid.ac/institutes/grid.260539.b", 
          "name": [
            "Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, ROC, Taiwan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Yichun", 
        "type": "Person"
      }
    ], 
    "datePublished": "2006-01-20", 
    "datePublishedReg": "2006-01-20", 
    "description": "BackgroundProgressive cell-mediated immunodeficiency with decrease of CD4+ lymphocyte count to less than or equal to 200 cells/mm3 is a major risk factor for colonization with Candida species and development of candidiasis. Oropharyngeal candidiasis may occur in up to 90% of human immunodeficiency virus (HIV)-infected patients during the course of the disease. This study is to determine the effect of prolonged highly active antiretroviral therapy (HAART) on oropharyngeal colonization with Candida species and oral candidiasis.MethodsA prospective, longitudinal follow-up study in HIV-infected patients receiving HAART.ResultsThe mean CD4+ count increased from 232.5 to 316 cells/mm3 and the proportion of patients whose CD4+ count less than 200 cells/mm3 decreased from 50.0% to 28.9% (p = 0.0003) in patients receiving HAART for at least 2 years. The prevalence of oral candidiasis decreased from 10.6% to 2.1% (p = 0.004). The decrease in Candida colonization was less impressive, falling from 57.8% to 46.5 % (p = 0.06). Of the 142 patients enrolled in at least two surveys, 48 (33.8%) remained colonized with Candida and 42 (29.6%) remained negative. In the remaining 52 patients, 34 switched from culture positive to negative, and an increase in CD4+ lymphocytes was noted in 91.2% of them. Among the 18 patients who switched from culture negative to positive, 61.1% also demonstrated an increase in CD4+ lymphocyte count (p = 0.01).ConclusionThese findings indicate that HAART is highly effective in decreasing oral candidiasis in association with a rise in CD4+ lymphocyte counts, but only marginally effective in eliminating Candida from the oropharynx.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/1471-2334-6-8", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024946", 
        "issn": [
          "1471-2334"
        ], 
        "name": "BMC Infectious Diseases", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "keywords": [
      "cells/mm3", 
      "lymphocyte count", 
      "oral candidiasis", 
      "active antiretroviral therapy", 
      "cell-mediated immunodeficiency", 
      "proportion of patients", 
      "human immunodeficiency virus", 
      "major risk factor", 
      "Candida species", 
      "development of candidiasis", 
      "mean CD4", 
      "prolonged HAART", 
      "antiretroviral therapy", 
      "oropharyngeal colonization", 
      "Candida colonization", 
      "immunodeficiency virus", 
      "risk factors", 
      "longitudinal follow", 
      "oral colonization", 
      "oropharyngeal candidiasis", 
      "CD4", 
      "HAART", 
      "patients", 
      "candidiasis", 
      "ConclusionThese findings", 
      "count", 
      "mm3", 
      "Candida", 
      "HIV", 
      "oropharynx", 
      "immunodeficiency", 
      "lymphocytes", 
      "therapy", 
      "follow", 
      "MethodsA", 
      "prevalence", 
      "disease", 
      "colonization", 
      "virus", 
      "decrease", 
      "study", 
      "association", 
      "increase", 
      "effect", 
      "years", 
      "culture", 
      "proportion", 
      "findings", 
      "course", 
      "factors", 
      "survey", 
      "development", 
      "rise", 
      "species"
    ], 
    "name": "Effect of prolonged HAART on oral colonization with Candidaand candidiasis", 
    "pagination": "8", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1030185655"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2334-6-8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16423306"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2334-6-8", 
      "https://app.dimensions.ai/details/publication/pub.1030185655"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_410.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/1471-2334-6-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-6-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-6-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-6-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-6-8'


 

This table displays all metadata directly associated to this object as RDF triples.

212 TRIPLES      20 PREDICATES      97 URIs      89 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2334-6-8 schema:about N0535a01e478b475ea2d11a314714a24b
2 N337ec4f6371f4b00bd8cd140d0143d67
3 N3e017e699d224131b5b289f5112ed21d
4 N3feef21ffc5d4f91b9f1b6b48f766d34
5 N4182ce466ecb47ee94bf889d780f2c81
6 N554c6d3dc0514ae79bdc1f6fcee49404
7 N745e49d367ca4dc8b554c87a7d0933b4
8 N7bec04e31dd24265bbec89e14d94c552
9 N8993650e8c6a40d7bbc93067912a10a5
10 N8cd539cb3d354f8a94034c9463cf91a9
11 N9109afbf1243426ca660f1d6d095a1b0
12 Nb7d97a5edb344719a1e807c4c0844abc
13 Nbd681ea319b2425e86c131dafeb264cd
14 Nd2ea69cd26704c1fafc6f70abc1d4bd0
15 Nd9930301a44d402ab75c98badb141414
16 Ne25ca8b9a6af4f13a63a3131ae7eb6fd
17 Nf55f5a46ca3c48bda6b87b2cc829429b
18 Nfa3625cbc0f54326881d6a44cb1a0c44
19 anzsrc-for:11
20 anzsrc-for:1103
21 schema:author Nb96e8d1f2d0642b7b9eb3a7d62a184ef
22 schema:datePublished 2006-01-20
23 schema:datePublishedReg 2006-01-20
24 schema:description BackgroundProgressive cell-mediated immunodeficiency with decrease of CD4+ lymphocyte count to less than or equal to 200 cells/mm3 is a major risk factor for colonization with Candida species and development of candidiasis. Oropharyngeal candidiasis may occur in up to 90% of human immunodeficiency virus (HIV)-infected patients during the course of the disease. This study is to determine the effect of prolonged highly active antiretroviral therapy (HAART) on oropharyngeal colonization with Candida species and oral candidiasis.MethodsA prospective, longitudinal follow-up study in HIV-infected patients receiving HAART.ResultsThe mean CD4+ count increased from 232.5 to 316 cells/mm3 and the proportion of patients whose CD4+ count less than 200 cells/mm3 decreased from 50.0% to 28.9% (p = 0.0003) in patients receiving HAART for at least 2 years. The prevalence of oral candidiasis decreased from 10.6% to 2.1% (p = 0.004). The decrease in Candida colonization was less impressive, falling from 57.8% to 46.5 % (p = 0.06). Of the 142 patients enrolled in at least two surveys, 48 (33.8%) remained colonized with Candida and 42 (29.6%) remained negative. In the remaining 52 patients, 34 switched from culture positive to negative, and an increase in CD4+ lymphocytes was noted in 91.2% of them. Among the 18 patients who switched from culture negative to positive, 61.1% also demonstrated an increase in CD4+ lymphocyte count (p = 0.01).ConclusionThese findings indicate that HAART is highly effective in decreasing oral candidiasis in association with a rise in CD4+ lymphocyte counts, but only marginally effective in eliminating Candida from the oropharynx.
25 schema:genre article
26 schema:isAccessibleForFree true
27 schema:isPartOf N9f1dffe0b4b043ddbfe9feaa9859efed
28 Neafcdc99617a4f2192b3878a9b65e8fe
29 sg:journal.1024946
30 schema:keywords CD4
31 Candida
32 Candida colonization
33 Candida species
34 ConclusionThese findings
35 HAART
36 HIV
37 MethodsA
38 active antiretroviral therapy
39 antiretroviral therapy
40 association
41 candidiasis
42 cell-mediated immunodeficiency
43 cells/mm3
44 colonization
45 count
46 course
47 culture
48 decrease
49 development
50 development of candidiasis
51 disease
52 effect
53 factors
54 findings
55 follow
56 human immunodeficiency virus
57 immunodeficiency
58 immunodeficiency virus
59 increase
60 longitudinal follow
61 lymphocyte count
62 lymphocytes
63 major risk factor
64 mean CD4
65 mm3
66 oral candidiasis
67 oral colonization
68 oropharyngeal candidiasis
69 oropharyngeal colonization
70 oropharynx
71 patients
72 prevalence
73 prolonged HAART
74 proportion
75 proportion of patients
76 rise
77 risk factors
78 species
79 study
80 survey
81 therapy
82 virus
83 years
84 schema:name Effect of prolonged HAART on oral colonization with Candidaand candidiasis
85 schema:pagination 8
86 schema:productId N798cf7ee7662487f8d46434aa5804c65
87 Naf208ec3708d4cbc8af2cc396ef0baed
88 Nb7248949f8264724977d1edfdc62ef0b
89 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030185655
90 https://doi.org/10.1186/1471-2334-6-8
91 schema:sdDatePublished 2022-12-01T06:25
92 schema:sdLicense https://scigraph.springernature.com/explorer/license/
93 schema:sdPublisher Nc71204ea9f8641f180616b8c27bb672c
94 schema:url https://doi.org/10.1186/1471-2334-6-8
95 sgo:license sg:explorer/license/
96 sgo:sdDataset articles
97 rdf:type schema:ScholarlyArticle
98 N0535a01e478b475ea2d11a314714a24b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Humans
100 rdf:type schema:DefinedTerm
101 N337ec4f6371f4b00bd8cd140d0143d67 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Oropharynx
103 rdf:type schema:DefinedTerm
104 N3e017e699d224131b5b289f5112ed21d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Candida
106 rdf:type schema:DefinedTerm
107 N3feef21ffc5d4f91b9f1b6b48f766d34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Longitudinal Studies
109 rdf:type schema:DefinedTerm
110 N4182ce466ecb47ee94bf889d780f2c81 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name HIV Infections
112 rdf:type schema:DefinedTerm
113 N554c6d3dc0514ae79bdc1f6fcee49404 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Anti-HIV Agents
115 rdf:type schema:DefinedTerm
116 N59e39d3b3a2b482dbd87e84ac99dc7c0 rdf:first Nf89b1d49de1840c182141018cdca587c
117 rdf:rest rdf:nil
118 N745e49d367ca4dc8b554c87a7d0933b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Drug Administration Schedule
120 rdf:type schema:DefinedTerm
121 N798cf7ee7662487f8d46434aa5804c65 schema:name doi
122 schema:value 10.1186/1471-2334-6-8
123 rdf:type schema:PropertyValue
124 N7bec04e31dd24265bbec89e14d94c552 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Prospective Studies
126 rdf:type schema:DefinedTerm
127 N8993650e8c6a40d7bbc93067912a10a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Adult
129 rdf:type schema:DefinedTerm
130 N8cd539cb3d354f8a94034c9463cf91a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Female
132 rdf:type schema:DefinedTerm
133 N9109afbf1243426ca660f1d6d095a1b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name CD4 Lymphocyte Count
135 rdf:type schema:DefinedTerm
136 N97281ad0fd5141089c72c9674af4f0e7 rdf:first sg:person.01062447152.68
137 rdf:rest Nee2205bde46348a48165b9303a4a3651
138 N9f1dffe0b4b043ddbfe9feaa9859efed schema:volumeNumber 6
139 rdf:type schema:PublicationVolume
140 Naf208ec3708d4cbc8af2cc396ef0baed schema:name dimensions_id
141 schema:value pub.1030185655
142 rdf:type schema:PropertyValue
143 Nb7248949f8264724977d1edfdc62ef0b schema:name pubmed_id
144 schema:value 16423306
145 rdf:type schema:PropertyValue
146 Nb7d97a5edb344719a1e807c4c0844abc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Candidiasis, Oral
148 rdf:type schema:DefinedTerm
149 Nb96e8d1f2d0642b7b9eb3a7d62a184ef rdf:first sg:person.01173034452.27
150 rdf:rest N97281ad0fd5141089c72c9674af4f0e7
151 Nbd681ea319b2425e86c131dafeb264cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Male
153 rdf:type schema:DefinedTerm
154 Nc71204ea9f8641f180616b8c27bb672c schema:name Springer Nature - SN SciGraph project
155 rdf:type schema:Organization
156 Nd2ea69cd26704c1fafc6f70abc1d4bd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name AIDS-Related Opportunistic Infections
158 rdf:type schema:DefinedTerm
159 Nd9930301a44d402ab75c98badb141414 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Anti-Bacterial Agents
161 rdf:type schema:DefinedTerm
162 Ne25ca8b9a6af4f13a63a3131ae7eb6fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Antifungal Agents
164 rdf:type schema:DefinedTerm
165 Neafcdc99617a4f2192b3878a9b65e8fe schema:issueNumber 1
166 rdf:type schema:PublicationIssue
167 Nee2205bde46348a48165b9303a4a3651 rdf:first sg:person.01312660244.19
168 rdf:rest N59e39d3b3a2b482dbd87e84ac99dc7c0
169 Nf55f5a46ca3c48bda6b87b2cc829429b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Risk Factors
171 rdf:type schema:DefinedTerm
172 Nf89b1d49de1840c182141018cdca587c schema:affiliation grid-institutes:grid.260539.b
173 schema:familyName Li
174 schema:givenName Yichun
175 rdf:type schema:Person
176 Nfa3625cbc0f54326881d6a44cb1a0c44 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Antiretroviral Therapy, Highly Active
178 rdf:type schema:DefinedTerm
179 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
180 schema:name Medical and Health Sciences
181 rdf:type schema:DefinedTerm
182 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
183 schema:name Clinical Sciences
184 rdf:type schema:DefinedTerm
185 sg:journal.1024946 schema:issn 1471-2334
186 schema:name BMC Infectious Diseases
187 schema:publisher Springer Nature
188 rdf:type schema:Periodical
189 sg:person.01062447152.68 schema:affiliation grid-institutes:grid.59784.37
190 schema:familyName Lo
191 schema:givenName Hsiu-Jung
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062447152.68
193 rdf:type schema:Person
194 sg:person.01173034452.27 schema:affiliation grid-institutes:grid.260539.b
195 schema:familyName Yang
196 schema:givenName Yun-Liang
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173034452.27
198 rdf:type schema:Person
199 sg:person.01312660244.19 schema:affiliation grid-institutes:grid.412094.a
200 schema:familyName Hung
201 schema:givenName Chien-Ching
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312660244.19
203 rdf:type schema:Person
204 grid-institutes:grid.260539.b schema:alternateName Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, ROC, Taiwan
205 schema:name Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, ROC, Taiwan
206 rdf:type schema:Organization
207 grid-institutes:grid.412094.a schema:alternateName Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, ROC, Taiwan
208 schema:name Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, ROC, Taiwan
209 rdf:type schema:Organization
210 grid-institutes:grid.59784.37 schema:alternateName Division of Clinical Research, National Health Research Institutes, Miaoli, ROC, Taiwan
211 schema:name Division of Clinical Research, National Health Research Institutes, Miaoli, ROC, Taiwan
212 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...