The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2005-11-03

AUTHORS

Yun-Liang Yang, Shu-Ying Li, Hsiao-Hsu Cheng, Hsiu-Jung Lo, TSARY Hospitals

ABSTRACT

BackgroundCandida species have various degrees of susceptibility to common antifungal drugs. The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing candidemia has been reported. Active surveillance may help us to monitor the trend of susceptibility to antifungal drugs and to determine if there is an emerging co-resistance to both drugs of Candida species, specifically, of C. glabrata in Taiwan.MethodsThe susceptibilities to amphotericin B and fluconazole of Candida species collected in 1999 and 2002 of the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) were determined by the microdilution method.ResultsThe antifungal susceptibilities of 342 and 456 isolates collected from 11 hospitals participating in both TSARY 1999 and TSARY 2002, respectively, have been determined. The resistance rate to amphotericin B has increased from 0.3% in the TSARY1999 to 2.2% in the TSARY 2002. In contrast, the resistance rate to fluconazole has decreased from 8.8% to 2.2%. Nevertheless, significantly more C. glabrata isolates were not susceptible to fluconazole in the TSARY 2002 (47.4%) than that in the TSARY 1999 (20.8%). There were 9.8% and 11% of C. glabrata isolates having susceptible-dose dependent and resistant phenotype to fluconazole in the TSARY 1999, verse 45.3% and 2.1% in the TSARY 2002.ConclusionThere was an increase of resistance rate to amphotericin B in C. glabrata. On the other hand, although the resistance rate to fluconazole has decreased, almost half of C. glabrata isolates were not susceptible to this drug. Hence, continuous monitoring the emerging of co-resistance to both amphotericin B and fluconazole of Candida species, specifically, of C. glabrata, will be an important early-warning system. More... »

PAGES

99

References to SciGraph publications

  • 1991-07. Emergence ofCandida krusei infections after therapy of oropharyngeal candidiasis with fluconazole in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1471-2334-5-99

    DOI

    http://dx.doi.org/10.1186/1471-2334-5-99

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1021616657

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16266438


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Public Health and Health Services", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Amphotericin B", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Antifungal Agents", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biological Evolution", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Candida", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Drug Resistance, Fungal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fluconazole", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Microbial Sensitivity Tests", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Taiwan", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, China", 
              "id": "http://www.grid.ac/institutes/grid.260539.b", 
              "name": [
                "Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yang", 
            "givenName": "Yun-Liang", 
            "id": "sg:person.01173034452.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173034452.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Laboratory for Mycopathogen, Chlamydia and Mycoplasma, Division of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, China", 
              "id": "http://www.grid.ac/institutes/grid.417579.9", 
              "name": [
                "Laboratory for Mycopathogen, Chlamydia and Mycoplasma, Division of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Shu-Ying", 
            "id": "sg:person.0762705365.19", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762705365.19"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Clinical Research, National Health Research Institutes, Miaoli, Taiwan, China", 
              "id": "http://www.grid.ac/institutes/grid.59784.37", 
              "name": [
                "Division of Clinical Research, National Health Research Institutes, Miaoli, Taiwan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cheng", 
            "givenName": "Hsiao-Hsu", 
            "id": "sg:person.01275703466.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01275703466.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Clinical Research, National Health Research Institutes, Miaoli, Taiwan, China", 
              "id": "http://www.grid.ac/institutes/grid.59784.37", 
              "name": [
                "Division of Clinical Research, National Health Research Institutes, Miaoli, Taiwan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lo", 
            "givenName": "Hsiu-Jung", 
            "id": "sg:person.01062447152.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062447152.68"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "TSARY Hospitals", 
            "id": "sg:person.014766766257.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014766766257.87"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/bf01967286", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032175444", 
              "https://doi.org/10.1007/bf01967286"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2005-11-03", 
        "datePublishedReg": "2005-11-03", 
        "description": "BackgroundCandida species have various degrees of susceptibility to common antifungal drugs. The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing candidemia has been reported. Active surveillance may help us to monitor the trend of susceptibility to antifungal drugs and to determine if there is an emerging co-resistance to both drugs of Candida species, specifically, of C. glabrata in Taiwan.MethodsThe susceptibilities to amphotericin B and fluconazole of Candida species collected in 1999 and 2002 of the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) were determined by the microdilution method.ResultsThe antifungal susceptibilities of 342 and 456 isolates collected from 11 hospitals participating in both TSARY 1999 and TSARY 2002, respectively, have been determined. The resistance rate to amphotericin B has increased from 0.3% in the TSARY1999 to 2.2% in the TSARY 2002. In contrast, the resistance rate to fluconazole has decreased from 8.8% to 2.2%. Nevertheless, significantly more C. glabrata isolates were not susceptible to fluconazole in the TSARY 2002 (47.4%) than that in the TSARY 1999 (20.8%). There were 9.8% and 11% of C. glabrata isolates having susceptible-dose dependent and resistant phenotype to fluconazole in the TSARY 1999, verse 45.3% and 2.1% in the TSARY 2002.ConclusionThere was an increase of resistance rate to amphotericin B in C. glabrata. On the other hand, although the resistance rate to fluconazole has decreased, almost half of C. glabrata isolates were not susceptible to this drug. Hence, continuous monitoring the emerging of co-resistance to both amphotericin B and fluconazole of Candida species, specifically, of C. glabrata, will be an important early-warning system.", 
        "genre": "article", 
        "id": "sg:pub.10.1186/1471-2334-5-99", 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1024946", 
            "issn": [
              "1471-2334"
            ], 
            "name": "BMC Infectious Diseases", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "5"
          }
        ], 
        "keywords": [
          "C. glabrata isolates", 
          "resistance rates", 
          "amphotericin B", 
          "Candida species", 
          "C. glabrata", 
          "glabrata isolates", 
          "trend of susceptibility", 
          "antifungal drugs", 
          "common antifungal drugs", 
          "active surveillance", 
          "Taiwan Surveillance", 
          "antifungal susceptibility", 
          "fluconazole", 
          "antimicrobial resistance", 
          "drugs", 
          "microdilution method", 
          "resistant phenotype", 
          "extent of resistance", 
          "Candida glabrata", 
          "glabrata", 
          "surveillance", 
          "degree of susceptibility", 
          "isolates", 
          "susceptibility", 
          "candidemia", 
          "hospital", 
          "rate", 
          "MethodsThe", 
          "continuous monitoring", 
          "phenotype", 
          "resistance", 
          "Taiwan", 
          "half", 
          "increase", 
          "contrast", 
          "trends", 
          "monitoring", 
          "extent", 
          "hand", 
          "degree", 
          "species", 
          "method", 
          "warning system", 
          "system", 
          "yeast"
        ], 
        "name": "The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan", 
        "pagination": "99", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1021616657"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/1471-2334-5-99"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "16266438"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/1471-2334-5-99", 
          "https://app.dimensions.ai/details/publication/pub.1021616657"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-08-04T16:56", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_411.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1186/1471-2334-5-99"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-5-99'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-5-99'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-5-99'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-5-99'


     

    This table displays all metadata directly associated to this object as RDF triples.

    177 TRIPLES      21 PREDICATES      80 URIs      71 LITERALS      16 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/1471-2334-5-99 schema:about N14e9b2bb188d436e8d2edbf496d10482
    2 N18057c115dd1486aa387ffc4662d9089
    3 N453843fa11a94c9b8b7f064e18b0c952
    4 N4f8b2bac0ce241f583a26973f0545b47
    5 N6e97319d56594c5a831e31e2b5391395
    6 N87b5cb5b94fe417db3a29819ed154aa0
    7 Nbb375d90b9104a9491d1dd39b9850bab
    8 Ndbc66780fac6417f98cee1e14c133192
    9 Nde2581ebd4b94191bd6b66dd7f873ac4
    10 anzsrc-for:11
    11 anzsrc-for:1117
    12 schema:author Nbacbedbc481541cfa45cdf2836ba8072
    13 schema:citation sg:pub.10.1007/bf01967286
    14 schema:datePublished 2005-11-03
    15 schema:datePublishedReg 2005-11-03
    16 schema:description BackgroundCandida species have various degrees of susceptibility to common antifungal drugs. The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing candidemia has been reported. Active surveillance may help us to monitor the trend of susceptibility to antifungal drugs and to determine if there is an emerging co-resistance to both drugs of Candida species, specifically, of C. glabrata in Taiwan.MethodsThe susceptibilities to amphotericin B and fluconazole of Candida species collected in 1999 and 2002 of the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) were determined by the microdilution method.ResultsThe antifungal susceptibilities of 342 and 456 isolates collected from 11 hospitals participating in both TSARY 1999 and TSARY 2002, respectively, have been determined. The resistance rate to amphotericin B has increased from 0.3% in the TSARY1999 to 2.2% in the TSARY 2002. In contrast, the resistance rate to fluconazole has decreased from 8.8% to 2.2%. Nevertheless, significantly more C. glabrata isolates were not susceptible to fluconazole in the TSARY 2002 (47.4%) than that in the TSARY 1999 (20.8%). There were 9.8% and 11% of C. glabrata isolates having susceptible-dose dependent and resistant phenotype to fluconazole in the TSARY 1999, verse 45.3% and 2.1% in the TSARY 2002.ConclusionThere was an increase of resistance rate to amphotericin B in C. glabrata. On the other hand, although the resistance rate to fluconazole has decreased, almost half of C. glabrata isolates were not susceptible to this drug. Hence, continuous monitoring the emerging of co-resistance to both amphotericin B and fluconazole of Candida species, specifically, of C. glabrata, will be an important early-warning system.
    17 schema:genre article
    18 schema:isAccessibleForFree true
    19 schema:isPartOf N29bb9a578b784920b990a5b2e95080dd
    20 Ne647cba33ff04c5fb17a8264e2d1b3e8
    21 sg:journal.1024946
    22 schema:keywords C. glabrata
    23 C. glabrata isolates
    24 Candida glabrata
    25 Candida species
    26 MethodsThe
    27 Taiwan
    28 Taiwan Surveillance
    29 active surveillance
    30 amphotericin B
    31 antifungal drugs
    32 antifungal susceptibility
    33 antimicrobial resistance
    34 candidemia
    35 common antifungal drugs
    36 continuous monitoring
    37 contrast
    38 degree
    39 degree of susceptibility
    40 drugs
    41 extent
    42 extent of resistance
    43 fluconazole
    44 glabrata
    45 glabrata isolates
    46 half
    47 hand
    48 hospital
    49 increase
    50 isolates
    51 method
    52 microdilution method
    53 monitoring
    54 phenotype
    55 rate
    56 resistance
    57 resistance rates
    58 resistant phenotype
    59 species
    60 surveillance
    61 susceptibility
    62 system
    63 trend of susceptibility
    64 trends
    65 warning system
    66 yeast
    67 schema:name The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan
    68 schema:pagination 99
    69 schema:productId N0bee8a412a9748febf5419408002c29c
    70 N4717614d788546009eaafc1f2e741ea2
    71 N76cde6d8e2c04064853bc46dc2307d12
    72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021616657
    73 https://doi.org/10.1186/1471-2334-5-99
    74 schema:sdDatePublished 2022-08-04T16:56
    75 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    76 schema:sdPublisher N7394c30b01724d69816752258338f27c
    77 schema:url https://doi.org/10.1186/1471-2334-5-99
    78 sgo:license sg:explorer/license/
    79 sgo:sdDataset articles
    80 rdf:type schema:ScholarlyArticle
    81 N0bee8a412a9748febf5419408002c29c schema:name doi
    82 schema:value 10.1186/1471-2334-5-99
    83 rdf:type schema:PropertyValue
    84 N14e9b2bb188d436e8d2edbf496d10482 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    85 schema:name Drug Resistance, Fungal
    86 rdf:type schema:DefinedTerm
    87 N18057c115dd1486aa387ffc4662d9089 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    88 schema:name Antifungal Agents
    89 rdf:type schema:DefinedTerm
    90 N29bb9a578b784920b990a5b2e95080dd schema:issueNumber 1
    91 rdf:type schema:PublicationIssue
    92 N453843fa11a94c9b8b7f064e18b0c952 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    93 schema:name Biological Evolution
    94 rdf:type schema:DefinedTerm
    95 N4717614d788546009eaafc1f2e741ea2 schema:name dimensions_id
    96 schema:value pub.1021616657
    97 rdf:type schema:PropertyValue
    98 N4f8b2bac0ce241f583a26973f0545b47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    99 schema:name Humans
    100 rdf:type schema:DefinedTerm
    101 N60b31837628e42b79dab835842c5019e rdf:first sg:person.014766766257.87
    102 rdf:rest rdf:nil
    103 N6caaa79e52314c3e97c036ae1dbffdc0 rdf:first sg:person.01062447152.68
    104 rdf:rest N60b31837628e42b79dab835842c5019e
    105 N6e97319d56594c5a831e31e2b5391395 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    106 schema:name Microbial Sensitivity Tests
    107 rdf:type schema:DefinedTerm
    108 N7394c30b01724d69816752258338f27c schema:name Springer Nature - SN SciGraph project
    109 rdf:type schema:Organization
    110 N76cde6d8e2c04064853bc46dc2307d12 schema:name pubmed_id
    111 schema:value 16266438
    112 rdf:type schema:PropertyValue
    113 N87b5cb5b94fe417db3a29819ed154aa0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    114 schema:name Fluconazole
    115 rdf:type schema:DefinedTerm
    116 Nad8b9fe7fa6e40c392673f7452a3b76c rdf:first sg:person.01275703466.26
    117 rdf:rest N6caaa79e52314c3e97c036ae1dbffdc0
    118 Nbacbedbc481541cfa45cdf2836ba8072 rdf:first sg:person.01173034452.27
    119 rdf:rest Nd6f22d87d86b471188f78522957f36f4
    120 Nbb375d90b9104a9491d1dd39b9850bab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Taiwan
    122 rdf:type schema:DefinedTerm
    123 Nd6f22d87d86b471188f78522957f36f4 rdf:first sg:person.0762705365.19
    124 rdf:rest Nad8b9fe7fa6e40c392673f7452a3b76c
    125 Ndbc66780fac6417f98cee1e14c133192 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    126 schema:name Amphotericin B
    127 rdf:type schema:DefinedTerm
    128 Nde2581ebd4b94191bd6b66dd7f873ac4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    129 schema:name Candida
    130 rdf:type schema:DefinedTerm
    131 Ne647cba33ff04c5fb17a8264e2d1b3e8 schema:volumeNumber 5
    132 rdf:type schema:PublicationVolume
    133 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    134 schema:name Medical and Health Sciences
    135 rdf:type schema:DefinedTerm
    136 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
    137 schema:name Public Health and Health Services
    138 rdf:type schema:DefinedTerm
    139 sg:journal.1024946 schema:issn 1471-2334
    140 schema:name BMC Infectious Diseases
    141 schema:publisher Springer Nature
    142 rdf:type schema:Periodical
    143 sg:person.01062447152.68 schema:affiliation grid-institutes:grid.59784.37
    144 schema:familyName Lo
    145 schema:givenName Hsiu-Jung
    146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062447152.68
    147 rdf:type schema:Person
    148 sg:person.01173034452.27 schema:affiliation grid-institutes:grid.260539.b
    149 schema:familyName Yang
    150 schema:givenName Yun-Liang
    151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173034452.27
    152 rdf:type schema:Person
    153 sg:person.01275703466.26 schema:affiliation grid-institutes:grid.59784.37
    154 schema:familyName Cheng
    155 schema:givenName Hsiao-Hsu
    156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01275703466.26
    157 rdf:type schema:Person
    158 sg:person.014766766257.87 schema:familyName TSARY Hospitals
    159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014766766257.87
    160 rdf:type schema:Person
    161 sg:person.0762705365.19 schema:affiliation grid-institutes:grid.417579.9
    162 schema:familyName Li
    163 schema:givenName Shu-Ying
    164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762705365.19
    165 rdf:type schema:Person
    166 sg:pub.10.1007/bf01967286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032175444
    167 https://doi.org/10.1007/bf01967286
    168 rdf:type schema:CreativeWork
    169 grid-institutes:grid.260539.b schema:alternateName Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, China
    170 schema:name Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, China
    171 rdf:type schema:Organization
    172 grid-institutes:grid.417579.9 schema:alternateName Laboratory for Mycopathogen, Chlamydia and Mycoplasma, Division of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, China
    173 schema:name Laboratory for Mycopathogen, Chlamydia and Mycoplasma, Division of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, China
    174 rdf:type schema:Organization
    175 grid-institutes:grid.59784.37 schema:alternateName Division of Clinical Research, National Health Research Institutes, Miaoli, Taiwan, China
    176 schema:name Division of Clinical Research, National Health Research Institutes, Miaoli, Taiwan, China
    177 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...