The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Harutaka Katano, Tsunekazu Hishima, Makoto Mochizuki, Yoshinori Kodama, Naoki Oyaizu, Yasunori Ota, Sohtaro Mine, Toru Igari, Atsushi Ajisawa, Katsuji Teruya, Junko Tanuma, Yoshimi Kikuchi, Tomoko Uehira, Takuma Shirasaka, Tomohiko Koibuchi, Aikichi Iwamoto, Shinichi Oka, Hideki Hasegawa, Seiji Okada, Akira Yasuoka

ABSTRACT

BACKGROUND: Opportunistic infections and malignancies such as malignant lymphoma and Kaposi sarcoma are significant complications of human immunodeficiency virus (HIV) infection. However, following the introduction of antiretroviral therapy in Japan in 1997, the incidence of clinical complications has decreased. In the present study, autopsy cases of HIV infection in Japan were retrospectively investigated to reveal the prevalence of opportunistic infections and malignancies. METHODS: A total of 225 autopsy cases of HIV infection identified at 4 Japanese hospitals from 1985-2012 were retrospectively reviewed. Clinical data were collected from patient medical records. RESULTS: Mean CD4 counts of patients were 77.0 cells/μL in patients who received any antiretroviral therapy during their lives (ART (+) patients) and 39.6 cells/μL in naïve patients (ART (-) patients). Cytomegalovirus infection (142 cases, 63.1%) and pneumocystis pneumonia (66 cases, 29.3%) were the most frequent opportunistic infections, and their prevalence was significantly lower in ART (+) patients than ART (-) patients. Non-Hodgkin lymphoma and Kaposi sarcoma were observed in 30.1% and 16.2% of ART (-) patients, and 37.9% and 15.2% of ART (+) patients, respectively. Malignant lymphoma was the most frequent cause of death, followed by cytomegalovirus infection regardless of ART. Non-acquired immunodeficiency syndrome (AIDS)-defining cancers such as liver and lung cancer caused death more frequently in ART (+) patients (9.1%) than in ART (-) patients (1.5%; P = 0.026). CONCLUSIONS: The prevalence of infectious diseases and malignancies were revealed in autopsy cases of HIV infection in Japan. The prevalence of cytomegalovirus infection and pneumocystis pneumonia at autopsy were lower in ART (+) patients than ART (-) patients. Higher prevalence of non-AIDS defining malignancies among ART (+) patients than ART (-) patients suggests that onsets of various opportunistic infections and malignancies should be carefully monitored regardless of whether the patient is receiving ART. More... »

PAGES

229

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2334-14-229

DOI

http://dx.doi.org/10.1186/1471-2334-14-229

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045865948

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24775713


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "AIDS-Related Opportunistic Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Retroviral Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autopsy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cause of Death", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Communicable Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Japan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prevalence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National Institute of Infectious Diseases", 
          "id": "https://www.grid.ac/institutes/grid.410795.e", 
          "name": [
            "Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, 162-8640, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Katano", 
        "givenName": "Harutaka", 
        "id": "sg:person.0742412363.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742412363.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Komagome Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415479.a", 
          "name": [
            "Department of Pathology, Tokyo Metropolitan Komagome Hospital, 3-18-22 Honkomagome, 113-8677, Bunkyo-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hishima", 
        "givenName": "Tsunekazu", 
        "id": "sg:person.01231355035.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231355035.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyorin University", 
          "id": "https://www.grid.ac/institutes/grid.411205.3", 
          "name": [
            "Department of Pathology, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan", 
            "Department of Pathology, Kyorin University School of Medicine, 6-20-2 Shinkawa, 181-8611, Mitaka City, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mochizuki", 
        "givenName": "Makoto", 
        "id": "sg:person.01350157074.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350157074.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka National Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416803.8", 
          "name": [
            "Department of Pathology, Osaka National Hospital, 2-1-14 Hoenzaka, 540-0006, Chuo-ku, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kodama", 
        "givenName": "Yoshinori", 
        "id": "sg:person.01335243744.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335243744.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Pathology, Research Hospital, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oyaizu", 
        "givenName": "Naoki", 
        "id": "sg:person.0704531460.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704531460.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Pathology, Research Hospital, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ota", 
        "givenName": "Yasunori", 
        "id": "sg:person.0665352420.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665352420.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Infectious Diseases", 
          "id": "https://www.grid.ac/institutes/grid.410795.e", 
          "name": [
            "Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, 162-8640, Shinjuku-ku, Tokyo, Japan", 
            "Department of Pathology, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mine", 
        "givenName": "Sohtaro", 
        "id": "sg:person.01007114574.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007114574.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pathology, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Igari", 
        "givenName": "Toru", 
        "id": "sg:person.01157645376.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157645376.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Komagome Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415479.a", 
          "name": [
            "Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital, 3-18-22 Honkomagome, 113-8677, Bunkyo-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ajisawa", 
        "givenName": "Atsushi", 
        "id": "sg:person.01054622155.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054622155.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Teruya", 
        "givenName": "Katsuji", 
        "id": "sg:person.01256426653.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256426653.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tanuma", 
        "givenName": "Junko", 
        "id": "sg:person.0655562370.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655562370.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kikuchi", 
        "givenName": "Yoshimi", 
        "id": "sg:person.01106673172.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106673172.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka National Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416803.8", 
          "name": [
            "Department of Infectious Diseases, Osaka National Hospital, 2-1-14 Hoenzaka, 540-0006, Chuo-ku, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uehira", 
        "givenName": "Tomoko", 
        "id": "sg:person.01343166467.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343166467.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka National Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416803.8", 
          "name": [
            "Department of Infectious Diseases, Osaka National Hospital, 2-1-14 Hoenzaka, 540-0006, Chuo-ku, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shirasaka", 
        "givenName": "Takuma", 
        "id": "sg:person.0624375051.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624375051.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Infectious Diseases and Applied Immunology, Hospital, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koibuchi", 
        "givenName": "Tomohiko", 
        "id": "sg:person.0632455720.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632455720.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Infectious Diseases and Applied Immunology, Hospital, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan", 
            "Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwamoto", 
        "givenName": "Aikichi", 
        "id": "sg:person.01056024132.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056024132.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oka", 
        "givenName": "Shinichi", 
        "id": "sg:person.0613744072.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613744072.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Infectious Diseases", 
          "id": "https://www.grid.ac/institutes/grid.410795.e", 
          "name": [
            "Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, 162-8640, Shinjuku-ku, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hasegawa", 
        "givenName": "Hideki", 
        "id": "sg:person.012430452031.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012430452031.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kumamoto University", 
          "id": "https://www.grid.ac/institutes/grid.274841.c", 
          "name": [
            "Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, 860-0811, Kumamoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okada", 
        "givenName": "Seiji", 
        "id": "sg:person.012362247702.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012362247702.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Oomura City Municipal Hospital, 133-2 Kogashima-cho, 865-8561, Omura City, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yasuoka", 
        "givenName": "Akira", 
        "id": "sg:person.01202661144.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202661144.94"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.micinf.2005.12.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000267921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10428190400015733", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000572244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/jinf.2001.0810", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004803552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6605756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007785375", 
          "https://doi.org/10.1038/sj.bjc.6605756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6605756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007785375", 
          "https://doi.org/10.1038/sj.bjc.6605756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32833a3967", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008601415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32833a3967", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008601415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32833a3967", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008601415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/cit369", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011075698"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/dji072", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011374704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.10790", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012723954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013691119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200008180-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013932045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200008180-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013932045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200008180-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013932045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200001070-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014749468"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200001070-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014749468"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2188/jea.10.65", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026027773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2002-01-0078", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026298843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1758-2652-15-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028998891", 
          "https://doi.org/10.1186/1758-2652-15-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200304001-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032122865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200304001-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032122865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/cit423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032697076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.1001194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033464667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32834344e6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035735269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32834344e6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035735269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32835935b3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039666695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32835935b3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039666695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2169/internalmedicine.50.4137", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043511198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0033685", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043966994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e3283319184", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044308985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e3283319184", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044308985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e3283319184", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044308985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6600452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044434738", 
          "https://doi.org/10.1038/sj.bjc.6600452"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6600452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044434738", 
          "https://doi.org/10.1038/sj.bjc.6600452"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(09)70282-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045419972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199803263381301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047239361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood.v98.12.3406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050062174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32835a5a7a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050134600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e32835a5a7a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050134600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.19.6626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051060532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12185-012-1127-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051212533", 
          "https://doi.org/10.1007/s12185-012-1127-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(00)02504-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051707130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.315.7117.1194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062781229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.315.7117.1194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062781229"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-12", 
    "datePublishedReg": "2014-12-01", 
    "description": "BACKGROUND: Opportunistic infections and malignancies such as malignant lymphoma and Kaposi sarcoma are significant complications of human immunodeficiency virus (HIV) infection. However, following the introduction of antiretroviral therapy in Japan in 1997, the incidence of clinical complications has decreased. In the present study, autopsy cases of HIV infection in Japan were retrospectively investigated to reveal the prevalence of opportunistic infections and malignancies.\nMETHODS: A total of 225 autopsy cases of HIV infection identified at 4 Japanese hospitals from 1985-2012 were retrospectively reviewed. Clinical data were collected from patient medical records.\nRESULTS: Mean CD4 counts of patients were 77.0 cells/\u03bcL in patients who received any antiretroviral therapy during their lives (ART (+) patients) and 39.6 cells/\u03bcL in na\u00efve patients (ART (-) patients). Cytomegalovirus infection (142 cases, 63.1%) and pneumocystis pneumonia (66 cases, 29.3%) were the most frequent opportunistic infections, and their prevalence was significantly lower in ART (+) patients than ART (-) patients. Non-Hodgkin lymphoma and Kaposi sarcoma were observed in 30.1% and 16.2% of ART (-) patients, and 37.9% and 15.2% of ART (+) patients, respectively. Malignant lymphoma was the most frequent cause of death, followed by cytomegalovirus infection regardless of ART. Non-acquired immunodeficiency syndrome (AIDS)-defining cancers such as liver and lung cancer caused death more frequently in ART (+) patients (9.1%) than in ART (-) patients (1.5%; P\u2009=\u20090.026).\nCONCLUSIONS: The prevalence of infectious diseases and malignancies were revealed in autopsy cases of HIV infection in Japan. The prevalence of cytomegalovirus infection and pneumocystis pneumonia at autopsy were lower in ART (+) patients than ART (-) patients. Higher prevalence of non-AIDS defining malignancies among ART (+) patients than ART (-) patients suggests that onsets of various opportunistic infections and malignancies should be carefully monitored regardless of whether the patient is receiving ART.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2334-14-229", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6099753", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1024946", 
        "issn": [
          "1471-2334"
        ], 
        "name": "BMC Infectious Diseases", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "14"
      }
    ], 
    "name": "The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan", 
    "pagination": "229", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "da7a8eb50ddb3b18865b1b1ed068ae993a06e6e213f6dd8734548d1e3de3abbf"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24775713"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968551"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2334-14-229"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1045865948"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2334-14-229", 
      "https://app.dimensions.ai/details/publication/pub.1045865948"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8663_00000507.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2334-14-229"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-14-229'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-14-229'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-14-229'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2334-14-229'


 

This table displays all metadata directly associated to this object as RDF triples.

413 TRIPLES      21 PREDICATES      80 URIs      41 LITERALS      29 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2334-14-229 schema:about N04b56262a1d542a8b8081c4c6b66b535
2 N10b6db77b1ce427da605a570907bcdbc
3 N167c9383174141f39b346a1da0ffac4e
4 N1f8533b11c2a44b8a0eb66f7a20eef63
5 N288f7c98595c4171b8676cf11c9c3ea3
6 N46e0b04e10bd4a0480a87be943719280
7 N52b4881b31f74f319a0a2b1de3c06e9e
8 N57fbaabde1944ca8b7c4cc0295f13be2
9 N58cc180fa8dd45e2bcf3fe6fd489c76f
10 N5e06b86c06b04dbcad1e24c174199bb3
11 N773adc9849f44fc6ac5940eaa38bf655
12 N7b442a5e1bee4bce8b558936bae04a43
13 N7bd41ab4bdb24b49bcf4c2043c6cbf0f
14 N7dd7bb4de952407bb5c748fc58986705
15 N8a8a54235bae4899a58ce474741ad944
16 Nb60103eabfeb4901a417eea246b1304e
17 Nb90618542cdb4ff19a3b6d0aa0ed34a8
18 Nc3bfbe3aef7d410eb5c48ce0c59a29a4
19 Ndf954582490a4ea3890f75607339048f
20 Ne4b295b2e6634a14b8897a412bcdefe8
21 anzsrc-for:11
22 anzsrc-for:1108
23 schema:author N78a1c09487794ff1a1b3b30988bb1987
24 schema:citation sg:pub.10.1007/s12185-012-1127-5
25 sg:pub.10.1038/sj.bjc.6600452
26 sg:pub.10.1038/sj.bjc.6605756
27 sg:pub.10.1186/1758-2652-15-1
28 https://doi.org/10.1002/cncr.25311
29 https://doi.org/10.1002/ijc.10790
30 https://doi.org/10.1016/j.micinf.2005.12.012
31 https://doi.org/10.1016/s0140-6736(00)02504-6
32 https://doi.org/10.1016/s1470-2045(09)70282-7
33 https://doi.org/10.1053/jinf.2001.0810
34 https://doi.org/10.1056/nejm199803263381301
35 https://doi.org/10.1080/10428190400015733
36 https://doi.org/10.1093/cid/cit369
37 https://doi.org/10.1093/cid/cit423
38 https://doi.org/10.1093/jnci/dji072
39 https://doi.org/10.1097/00002030-200001070-00008
40 https://doi.org/10.1097/00002030-200008180-00001
41 https://doi.org/10.1097/00002030-200304001-00012
42 https://doi.org/10.1097/qad.0b013e3283319184
43 https://doi.org/10.1097/qad.0b013e32833a3967
44 https://doi.org/10.1097/qad.0b013e32834344e6
45 https://doi.org/10.1097/qad.0b013e32835935b3
46 https://doi.org/10.1097/qad.0b013e32835a5a7a
47 https://doi.org/10.1136/bmj.315.7117.1194
48 https://doi.org/10.1182/blood-2002-01-0078
49 https://doi.org/10.1182/blood.v98.12.3406
50 https://doi.org/10.1200/jco.2008.19.6626
51 https://doi.org/10.1371/journal.pmed.1001194
52 https://doi.org/10.1371/journal.pone.0033685
53 https://doi.org/10.2169/internalmedicine.50.4137
54 https://doi.org/10.2188/jea.10.65
55 schema:datePublished 2014-12
56 schema:datePublishedReg 2014-12-01
57 schema:description BACKGROUND: Opportunistic infections and malignancies such as malignant lymphoma and Kaposi sarcoma are significant complications of human immunodeficiency virus (HIV) infection. However, following the introduction of antiretroviral therapy in Japan in 1997, the incidence of clinical complications has decreased. In the present study, autopsy cases of HIV infection in Japan were retrospectively investigated to reveal the prevalence of opportunistic infections and malignancies. METHODS: A total of 225 autopsy cases of HIV infection identified at 4 Japanese hospitals from 1985-2012 were retrospectively reviewed. Clinical data were collected from patient medical records. RESULTS: Mean CD4 counts of patients were 77.0 cells/μL in patients who received any antiretroviral therapy during their lives (ART (+) patients) and 39.6 cells/μL in naïve patients (ART (-) patients). Cytomegalovirus infection (142 cases, 63.1%) and pneumocystis pneumonia (66 cases, 29.3%) were the most frequent opportunistic infections, and their prevalence was significantly lower in ART (+) patients than ART (-) patients. Non-Hodgkin lymphoma and Kaposi sarcoma were observed in 30.1% and 16.2% of ART (-) patients, and 37.9% and 15.2% of ART (+) patients, respectively. Malignant lymphoma was the most frequent cause of death, followed by cytomegalovirus infection regardless of ART. Non-acquired immunodeficiency syndrome (AIDS)-defining cancers such as liver and lung cancer caused death more frequently in ART (+) patients (9.1%) than in ART (-) patients (1.5%; P = 0.026). CONCLUSIONS: The prevalence of infectious diseases and malignancies were revealed in autopsy cases of HIV infection in Japan. The prevalence of cytomegalovirus infection and pneumocystis pneumonia at autopsy were lower in ART (+) patients than ART (-) patients. Higher prevalence of non-AIDS defining malignancies among ART (+) patients than ART (-) patients suggests that onsets of various opportunistic infections and malignancies should be carefully monitored regardless of whether the patient is receiving ART.
58 schema:genre research_article
59 schema:inLanguage en
60 schema:isAccessibleForFree true
61 schema:isPartOf N93eccbff9af54f488284542b8f6a6d39
62 Ncbed8028854d4b91a07e91c81aab0533
63 sg:journal.1024946
64 schema:name The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan
65 schema:pagination 229
66 schema:productId N1d400ac95df74474b2c6dad82f23cce6
67 N7c8d06e892ac490c86cc35288e9fa0a8
68 N9acee9b720a74e33a0552c274f5f3704
69 Naab765b028884120a586428c42a93a03
70 Nf3243b96ece8413f94f347935cca9ba3
71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045865948
72 https://doi.org/10.1186/1471-2334-14-229
73 schema:sdDatePublished 2019-04-10T14:59
74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
75 schema:sdPublisher Nc22d0626b0594ce5a0e55db987410905
76 schema:url http://link.springer.com/10.1186%2F1471-2334-14-229
77 sgo:license sg:explorer/license/
78 sgo:sdDataset articles
79 rdf:type schema:ScholarlyArticle
80 N02c2de3384244a339f71c0c27a075021 schema:name AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
81 rdf:type schema:Organization
82 N04b56262a1d542a8b8081c4c6b66b535 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Japan
84 rdf:type schema:DefinedTerm
85 N10b6db77b1ce427da605a570907bcdbc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Middle Aged
87 rdf:type schema:DefinedTerm
88 N130216ed6a7a4629a629e3b694d75be9 rdf:first sg:person.01350157074.94
89 rdf:rest Nc54a8383180d4136b23618bbd4c41558
90 N167c9383174141f39b346a1da0ffac4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Neoplasms
92 rdf:type schema:DefinedTerm
93 N1777fb7d36c845e69cd0971e8eb80ca0 rdf:first sg:person.012362247702.07
94 rdf:rest Nd762a1136da448d78ffc40bfd0935153
95 N1d400ac95df74474b2c6dad82f23cce6 schema:name readcube_id
96 schema:value da7a8eb50ddb3b18865b1b1ed068ae993a06e6e213f6dd8734548d1e3de3abbf
97 rdf:type schema:PropertyValue
98 N1f8533b11c2a44b8a0eb66f7a20eef63 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Communicable Diseases
100 rdf:type schema:DefinedTerm
101 N288f7c98595c4171b8676cf11c9c3ea3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Adult
103 rdf:type schema:DefinedTerm
104 N2c73caf2c2c14e649b6a48bb308ddc62 schema:name AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
105 rdf:type schema:Organization
106 N46e0b04e10bd4a0480a87be943719280 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Humans
108 rdf:type schema:DefinedTerm
109 N4a1feb85dbd547209421bf942c85396f rdf:first sg:person.01007114574.13
110 rdf:rest Nd5ecad07b44b4672932f810875517c7e
111 N513cb6c9288f49f898fe000094d8c26b rdf:first sg:person.01231355035.79
112 rdf:rest N130216ed6a7a4629a629e3b694d75be9
113 N52b4881b31f74f319a0a2b1de3c06e9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Male
115 rdf:type schema:DefinedTerm
116 N57fbaabde1944ca8b7c4cc0295f13be2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Anti-Retroviral Agents
118 rdf:type schema:DefinedTerm
119 N58cc180fa8dd45e2bcf3fe6fd489c76f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name HIV Infections
121 rdf:type schema:DefinedTerm
122 N5e06b86c06b04dbcad1e24c174199bb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Retrospective Studies
124 rdf:type schema:DefinedTerm
125 N630a80a61f024619b6750637b0806ae1 rdf:first sg:person.01054622155.31
126 rdf:rest Naa91ee7212434e18a4258144931c7747
127 N63b17fcd3d5c4695a143db229d855e7e rdf:first sg:person.0655562370.95
128 rdf:rest N95b47c7229b94122bf529a79ff91d91b
129 N671a2d0d7dda4fb382ca4c319436aee5 rdf:first sg:person.0624375051.43
130 rdf:rest Na4146f924a0d41ab8a92b02e5d5fd46a
131 N773adc9849f44fc6ac5940eaa38bf655 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Young Adult
133 rdf:type schema:DefinedTerm
134 N78a1c09487794ff1a1b3b30988bb1987 rdf:first sg:person.0742412363.13
135 rdf:rest N513cb6c9288f49f898fe000094d8c26b
136 N7b442a5e1bee4bce8b558936bae04a43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name AIDS-Related Opportunistic Infections
138 rdf:type schema:DefinedTerm
139 N7bd41ab4bdb24b49bcf4c2043c6cbf0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Aged
141 rdf:type schema:DefinedTerm
142 N7c8d06e892ac490c86cc35288e9fa0a8 schema:name pubmed_id
143 schema:value 24775713
144 rdf:type schema:PropertyValue
145 N7dd7bb4de952407bb5c748fc58986705 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Autopsy
147 rdf:type schema:DefinedTerm
148 N8a8a54235bae4899a58ce474741ad944 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Female
150 rdf:type schema:DefinedTerm
151 N93eccbff9af54f488284542b8f6a6d39 schema:issueNumber 1
152 rdf:type schema:PublicationIssue
153 N95a60bbee68f4185833da1e143e99504 rdf:first sg:person.0665352420.95
154 rdf:rest N4a1feb85dbd547209421bf942c85396f
155 N95b47c7229b94122bf529a79ff91d91b rdf:first sg:person.01106673172.47
156 rdf:rest Nf29e207403b0495f811de0bcda5f028d
157 N9955af22d3d24358a873c94201ab3ee6 schema:name Department of Pathology, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
158 rdf:type schema:Organization
159 N9acee9b720a74e33a0552c274f5f3704 schema:name nlm_unique_id
160 schema:value 100968551
161 rdf:type schema:PropertyValue
162 Na4146f924a0d41ab8a92b02e5d5fd46a rdf:first sg:person.0632455720.46
163 rdf:rest Na8345fc4b16f4d82a11a45ad92b2238b
164 Na5ac46e265c34943931e2406f584af0d rdf:first sg:person.0704531460.54
165 rdf:rest N95a60bbee68f4185833da1e143e99504
166 Na8345fc4b16f4d82a11a45ad92b2238b rdf:first sg:person.01056024132.18
167 rdf:rest Na98fe6571e0a4e02964f56afb3311dca
168 Na98fe6571e0a4e02964f56afb3311dca rdf:first sg:person.0613744072.48
169 rdf:rest Nf0c57e167e5c49369fdcf3b684fe3e15
170 Naa91ee7212434e18a4258144931c7747 rdf:first sg:person.01256426653.32
171 rdf:rest N63b17fcd3d5c4695a143db229d855e7e
172 Naab765b028884120a586428c42a93a03 schema:name dimensions_id
173 schema:value pub.1045865948
174 rdf:type schema:PropertyValue
175 Nb60103eabfeb4901a417eea246b1304e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Aged, 80 and over
177 rdf:type schema:DefinedTerm
178 Nb90618542cdb4ff19a3b6d0aa0ed34a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Adolescent
180 rdf:type schema:DefinedTerm
181 Nc22d0626b0594ce5a0e55db987410905 schema:name Springer Nature - SN SciGraph project
182 rdf:type schema:Organization
183 Nc38f076970944b7ea30f1f0d4e41c6de schema:name AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
184 rdf:type schema:Organization
185 Nc3bfbe3aef7d410eb5c48ce0c59a29a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Cause of Death
187 rdf:type schema:DefinedTerm
188 Nc54a8383180d4136b23618bbd4c41558 rdf:first sg:person.01335243744.91
189 rdf:rest Na5ac46e265c34943931e2406f584af0d
190 Ncb4c2aa4266d4c73881f83e67113ac29 schema:name Oomura City Municipal Hospital, 133-2 Kogashima-cho, 865-8561, Omura City, Nagasaki, Japan
191 rdf:type schema:Organization
192 Ncbed8028854d4b91a07e91c81aab0533 schema:volumeNumber 14
193 rdf:type schema:PublicationVolume
194 Nd5ecad07b44b4672932f810875517c7e rdf:first sg:person.01157645376.84
195 rdf:rest N630a80a61f024619b6750637b0806ae1
196 Nd762a1136da448d78ffc40bfd0935153 rdf:first sg:person.01202661144.94
197 rdf:rest rdf:nil
198 Ndf954582490a4ea3890f75607339048f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Child
200 rdf:type schema:DefinedTerm
201 Ne4b295b2e6634a14b8897a412bcdefe8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Prevalence
203 rdf:type schema:DefinedTerm
204 Nf0c57e167e5c49369fdcf3b684fe3e15 rdf:first sg:person.012430452031.47
205 rdf:rest N1777fb7d36c845e69cd0971e8eb80ca0
206 Nf29e207403b0495f811de0bcda5f028d rdf:first sg:person.01343166467.14
207 rdf:rest N671a2d0d7dda4fb382ca4c319436aee5
208 Nf3243b96ece8413f94f347935cca9ba3 schema:name doi
209 schema:value 10.1186/1471-2334-14-229
210 rdf:type schema:PropertyValue
211 Nfdc08a6b8e464e74bebf8c6add2dff3c schema:name AIDS Clinical Center, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
212 rdf:type schema:Organization
213 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
214 schema:name Medical and Health Sciences
215 rdf:type schema:DefinedTerm
216 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
217 schema:name Medical Microbiology
218 rdf:type schema:DefinedTerm
219 sg:grant.6099753 http://pending.schema.org/fundedItem sg:pub.10.1186/1471-2334-14-229
220 rdf:type schema:MonetaryGrant
221 sg:journal.1024946 schema:issn 1471-2334
222 schema:name BMC Infectious Diseases
223 rdf:type schema:Periodical
224 sg:person.01007114574.13 schema:affiliation https://www.grid.ac/institutes/grid.410795.e
225 schema:familyName Mine
226 schema:givenName Sohtaro
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007114574.13
228 rdf:type schema:Person
229 sg:person.01054622155.31 schema:affiliation https://www.grid.ac/institutes/grid.415479.a
230 schema:familyName Ajisawa
231 schema:givenName Atsushi
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054622155.31
233 rdf:type schema:Person
234 sg:person.01056024132.18 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
235 schema:familyName Iwamoto
236 schema:givenName Aikichi
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056024132.18
238 rdf:type schema:Person
239 sg:person.01106673172.47 schema:affiliation N2c73caf2c2c14e649b6a48bb308ddc62
240 schema:familyName Kikuchi
241 schema:givenName Yoshimi
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106673172.47
243 rdf:type schema:Person
244 sg:person.01157645376.84 schema:affiliation N9955af22d3d24358a873c94201ab3ee6
245 schema:familyName Igari
246 schema:givenName Toru
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157645376.84
248 rdf:type schema:Person
249 sg:person.01202661144.94 schema:affiliation Ncb4c2aa4266d4c73881f83e67113ac29
250 schema:familyName Yasuoka
251 schema:givenName Akira
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202661144.94
253 rdf:type schema:Person
254 sg:person.01231355035.79 schema:affiliation https://www.grid.ac/institutes/grid.415479.a
255 schema:familyName Hishima
256 schema:givenName Tsunekazu
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231355035.79
258 rdf:type schema:Person
259 sg:person.012362247702.07 schema:affiliation https://www.grid.ac/institutes/grid.274841.c
260 schema:familyName Okada
261 schema:givenName Seiji
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012362247702.07
263 rdf:type schema:Person
264 sg:person.012430452031.47 schema:affiliation https://www.grid.ac/institutes/grid.410795.e
265 schema:familyName Hasegawa
266 schema:givenName Hideki
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012430452031.47
268 rdf:type schema:Person
269 sg:person.01256426653.32 schema:affiliation N02c2de3384244a339f71c0c27a075021
270 schema:familyName Teruya
271 schema:givenName Katsuji
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256426653.32
273 rdf:type schema:Person
274 sg:person.01335243744.91 schema:affiliation https://www.grid.ac/institutes/grid.416803.8
275 schema:familyName Kodama
276 schema:givenName Yoshinori
277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335243744.91
278 rdf:type schema:Person
279 sg:person.01343166467.14 schema:affiliation https://www.grid.ac/institutes/grid.416803.8
280 schema:familyName Uehira
281 schema:givenName Tomoko
282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343166467.14
283 rdf:type schema:Person
284 sg:person.01350157074.94 schema:affiliation https://www.grid.ac/institutes/grid.411205.3
285 schema:familyName Mochizuki
286 schema:givenName Makoto
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350157074.94
288 rdf:type schema:Person
289 sg:person.0613744072.48 schema:affiliation Nfdc08a6b8e464e74bebf8c6add2dff3c
290 schema:familyName Oka
291 schema:givenName Shinichi
292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613744072.48
293 rdf:type schema:Person
294 sg:person.0624375051.43 schema:affiliation https://www.grid.ac/institutes/grid.416803.8
295 schema:familyName Shirasaka
296 schema:givenName Takuma
297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624375051.43
298 rdf:type schema:Person
299 sg:person.0632455720.46 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
300 schema:familyName Koibuchi
301 schema:givenName Tomohiko
302 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632455720.46
303 rdf:type schema:Person
304 sg:person.0655562370.95 schema:affiliation Nc38f076970944b7ea30f1f0d4e41c6de
305 schema:familyName Tanuma
306 schema:givenName Junko
307 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655562370.95
308 rdf:type schema:Person
309 sg:person.0665352420.95 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
310 schema:familyName Ota
311 schema:givenName Yasunori
312 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665352420.95
313 rdf:type schema:Person
314 sg:person.0704531460.54 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
315 schema:familyName Oyaizu
316 schema:givenName Naoki
317 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704531460.54
318 rdf:type schema:Person
319 sg:person.0742412363.13 schema:affiliation https://www.grid.ac/institutes/grid.410795.e
320 schema:familyName Katano
321 schema:givenName Harutaka
322 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742412363.13
323 rdf:type schema:Person
324 sg:pub.10.1007/s12185-012-1127-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051212533
325 https://doi.org/10.1007/s12185-012-1127-5
326 rdf:type schema:CreativeWork
327 sg:pub.10.1038/sj.bjc.6600452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044434738
328 https://doi.org/10.1038/sj.bjc.6600452
329 rdf:type schema:CreativeWork
330 sg:pub.10.1038/sj.bjc.6605756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007785375
331 https://doi.org/10.1038/sj.bjc.6605756
332 rdf:type schema:CreativeWork
333 sg:pub.10.1186/1758-2652-15-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028998891
334 https://doi.org/10.1186/1758-2652-15-1
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1002/cncr.25311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013691119
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1002/ijc.10790 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012723954
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1016/j.micinf.2005.12.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000267921
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/s0140-6736(00)02504-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051707130
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1016/s1470-2045(09)70282-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045419972
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1053/jinf.2001.0810 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004803552
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1056/nejm199803263381301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047239361
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1080/10428190400015733 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000572244
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1093/cid/cit369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011075698
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1093/cid/cit423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032697076
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1093/jnci/dji072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011374704
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1097/00002030-200001070-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014749468
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1097/00002030-200008180-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013932045
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1097/00002030-200304001-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032122865
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1097/qad.0b013e3283319184 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044308985
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1097/qad.0b013e32833a3967 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008601415
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1097/qad.0b013e32834344e6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035735269
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1097/qad.0b013e32835935b3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039666695
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1097/qad.0b013e32835a5a7a schema:sameAs https://app.dimensions.ai/details/publication/pub.1050134600
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1136/bmj.315.7117.1194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062781229
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1182/blood-2002-01-0078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026298843
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1182/blood.v98.12.3406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050062174
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1200/jco.2008.19.6626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051060532
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1371/journal.pmed.1001194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033464667
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1371/journal.pone.0033685 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043966994
385 rdf:type schema:CreativeWork
386 https://doi.org/10.2169/internalmedicine.50.4137 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043511198
387 rdf:type schema:CreativeWork
388 https://doi.org/10.2188/jea.10.65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026027773
389 rdf:type schema:CreativeWork
390 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
391 schema:name Department of Infectious Diseases and Applied Immunology, Hospital, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan
392 Department of Pathology, Research Hospital, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan
393 Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, the University of Tokyo, 4-6-1 Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan
394 rdf:type schema:Organization
395 https://www.grid.ac/institutes/grid.274841.c schema:alternateName Kumamoto University
396 schema:name Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, 860-0811, Kumamoto, Japan
397 rdf:type schema:Organization
398 https://www.grid.ac/institutes/grid.410795.e schema:alternateName National Institute of Infectious Diseases
399 schema:name Department of Pathology, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
400 Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, 162-8640, Shinjuku-ku, Tokyo, Japan
401 rdf:type schema:Organization
402 https://www.grid.ac/institutes/grid.411205.3 schema:alternateName Kyorin University
403 schema:name Department of Pathology, Kyorin University School of Medicine, 6-20-2 Shinkawa, 181-8611, Mitaka City, Tokyo, Japan
404 Department of Pathology, National Center for Global Health and Medicine Hospital, 1-21-1 Toyama, 162-8655, Shinjuku-ku, Tokyo, Japan
405 rdf:type schema:Organization
406 https://www.grid.ac/institutes/grid.415479.a schema:alternateName Tokyo Metropolitan Komagome Hospital
407 schema:name Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital, 3-18-22 Honkomagome, 113-8677, Bunkyo-ku, Tokyo, Japan
408 Department of Pathology, Tokyo Metropolitan Komagome Hospital, 3-18-22 Honkomagome, 113-8677, Bunkyo-ku, Tokyo, Japan
409 rdf:type schema:Organization
410 https://www.grid.ac/institutes/grid.416803.8 schema:alternateName Osaka National Hospital
411 schema:name Department of Infectious Diseases, Osaka National Hospital, 2-1-14 Hoenzaka, 540-0006, Chuo-ku, Osaka, Japan
412 Department of Pathology, Osaka National Hospital, 2-1-14 Hoenzaka, 540-0006, Chuo-ku, Osaka, Japan
413 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...