Tuberculosis in Kazakhstan: analysis of risk determinants in national surveillance data View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-12

AUTHORS

Assel Terlikbayeva, Sabrina Hermosilla, Sandro Galea, Neil Schluger, Saltanat Yegeubayeva, Tleukhan Abildayev, Talgat Muminov, Farida Akiyanova, Laura Bartkowiak, Zhaksybay Zhumadilov, Almaz Sharman, Nabila El-Bassel

ABSTRACT

BACKGROUND: Development of tuberculosis (TB) is determined by various risk factors and the interactions of temporal and spatial distributions. The aim of this study was to identify the most salient risk factors for TB disease as well as multidrug resistant TB (MDR-TB) at the oblast (provincial) level in Kazakhstan. METHODS: Correlational and descriptive analyses were conducted at the oblast and national level using data provided by the country's National Institute of Geography (NIG) and the National Tuberculosis Program (NTP). Reported incident case notification rates (CNRs) and prevalence vary by oblast, thus the study investigated which determinants contributed to this regional variation and compared burdens among oblasts. RESULTS: The results showed that while tuberculosis CNRs decreased over the study period, MDR-TB conversely increased. Two oblasts -Atyrauskaya and Mangystauskaya - presented especially significant anomalies with large decreases in TB incident CNRs coupled with comparatively large increases in MDR-TB incident CNRs. CONCLUSION: Understanding the distribution of TB and MDR-TB cases and associated risk factors, especially the "unknown risk factor" categorization points to the need for future research. More... »

PAGES

262

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2334-12-262

DOI

http://dx.doi.org/10.1186/1471-2334-12-262

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030987660

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23075260


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