Fatty acid composition of subcutaneous adipose tissue and gastric mucosa: is there a relation with gastric ulceration? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-12

AUTHORS

Vasileios A Pagkalos, Joanna Moschandreas, Michael Kiriakakis, Maria Roussomoustakaki, Anthony Kafatos, Elias Kouroumalis

ABSTRACT

BACKGROUND: Both in vitro and epidemiological studies indicate that dietary polyunsaturated fatty acids may play a protective role against peptic ulcer in humans. Adipose tissue fatty acid composition is thought to reflect dietary fatty acid intake. The aim of the present study is to investigate adipose and gastric mucosa fatty acid levels in relation to gastric ulceration status. METHODS: Fifty two adult outpatients undergoing upper gastrointestinal tract endoscopy participated in the study. Adipose tissue samples were taken from the abdomen and buttock during the endoscopy procedure and samples from gastric tissue were taken from a subsample of 30 subjects. The presence of Helicobacter pylori was determined using the CLO test. Capillary gas chromatography was used for the extraction of 36 and 42 adipose tissue and gastric mucosa lipids respectively. RESULTS: The monounsaturated fatty acids (MUFAs) C18:1n-12c, C16:1n-5, C16:4n-1 and the polyunsaturated fatty acids (PUFAs) C16:3n-4, C20:3n-3, C20:4n-6, C21:5n-3 and C18:2n-9c,12t of the gastric mucosa were present in higher proportions in ulcer negative patients. These unsaturated fatty acids, however, each contributed less than 1% on average to total fatty acid content. In addition, higher average levels of eicosapentaenoic acid (EPA) C20:5n-3 and docosahexaenoic acid (DHA) C22:6n-3 were detected in abdominal and buttock samples in CLO negative controls, compared to CLO positive controls. Adipose tissue and gastric mucosa n-6 and trans fatty acid levels were positively linearly correlated (r = 0.37 and 0.41 for n-6 and trans fatty acids respectively). CONCLUSION: Certain minor MUFAs and PUFAs of the gastric mucosa appear to be present in higher proportions in ulcer negative patients. Overall, the findings provide only weak evidence of an association between the gastric mucosal fatty acids and the presence of gastric ulceration. The higher average levels of EPA and DHA in abdominal and buttock adipose tissue in CLO negative controls could be an indicator that dietary FAs inhibit Helicobacter pylori growth. Larger studies are necessary to provide evidence of a biologically relevant effect. More... »

PAGES

9

References to SciGraph publications

  • 2000-02. Modulatory effects of dietary lipids on immune system functions in IMMUNOLOGY AND CELL BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1471-230x-9-9

    DOI

    http://dx.doi.org/10.1186/1471-230x-9-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010199446

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19166613


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Buttocks", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Case-Control Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Endoscopy", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fatty Acids", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gastric Mucosa", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Helicobacter Infections", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Helicobacter pylori", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Stomach Ulcer", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Subcutaneous Fat, Abdominal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Young Adult", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University Hospital of Heraklion", 
              "id": "https://www.grid.ac/institutes/grid.412481.a", 
              "name": [
                "Department of Gastroenterology, University Hospital of Heraklion, Heraklion, Crete, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pagkalos", 
            "givenName": "Vasileios A", 
            "id": "sg:person.01015756304.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015756304.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Crete", 
              "id": "https://www.grid.ac/institutes/grid.8127.c", 
              "name": [
                "Department of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Crete, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Moschandreas", 
            "givenName": "Joanna", 
            "id": "sg:person.01113231337.54", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113231337.54"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Crete", 
              "id": "https://www.grid.ac/institutes/grid.8127.c", 
              "name": [
                "Department of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Crete, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kiriakakis", 
            "givenName": "Michael", 
            "id": "sg:person.01134776140.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134776140.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Heraklion", 
              "id": "https://www.grid.ac/institutes/grid.412481.a", 
              "name": [
                "Department of Gastroenterology, University Hospital of Heraklion, Heraklion, Crete, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Roussomoustakaki", 
            "givenName": "Maria", 
            "id": "sg:person.01022653073.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022653073.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Crete", 
              "id": "https://www.grid.ac/institutes/grid.8127.c", 
              "name": [
                "Department of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Crete, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kafatos", 
            "givenName": "Anthony", 
            "id": "sg:person.07563302174.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07563302174.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Heraklion", 
              "id": "https://www.grid.ac/institutes/grid.412481.a", 
              "name": [
                "Department of Gastroenterology, University Hospital of Heraklion, Heraklion, Crete, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kouroumalis", 
            "givenName": "Elias", 
            "id": "sg:person.0605456342.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605456342.96"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1111/j.1365-2036.1988.tb00686.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005022645"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/j.gastro.2007.11.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005806285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/oxfordjournals.epirev.a018040", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008722812"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/pmed.2001.0930", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012916883"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(84)91816-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014931042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.188.12.2277", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020053658"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1079/bjn19970171", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021360136"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1079/bjn19970171", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021360136"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.31.9.997", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024572951"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1635231100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027161070"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.52.9.1242", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027639982"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1254/jphs.cp0070034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036555531"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0889-8553(05)70218-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036619233"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0889-8553(05)70218-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036619233"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m011695200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040057826"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/iai.69.3.1714-1721.2001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040402521"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(02)11030-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046319386"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.35.11.1557", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047829839"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mog.0b013e3282f02607", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048775336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/mog.0b013e3282f02607", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048775336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1046/j.1440-1711.2000.00875.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049182667", 
              "https://doi.org/10.1046/j.1440-1711.2000.00875.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1079/pns19980078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050215823"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1079/pns19980078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050215823"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac60235a044", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055051243"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00042737-200110000-00027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060297492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/0929867053363478", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069160453"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4067/s0716-97602002000200003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072191682"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074962553", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcn/76.4.750", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1075157208"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077131635", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077235150", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079856309", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcn/42.3.560", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1080094625"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080445796", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081970903", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcn/57.1.70", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082798066"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083365999", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/acprof:oso/9780195122978.001.0001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1098760740"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2009-12", 
        "datePublishedReg": "2009-12-01", 
        "description": "BACKGROUND: Both in vitro and epidemiological studies indicate that dietary polyunsaturated fatty acids may play a protective role against peptic ulcer in humans. Adipose tissue fatty acid composition is thought to reflect dietary fatty acid intake. The aim of the present study is to investigate adipose and gastric mucosa fatty acid levels in relation to gastric ulceration status.\nMETHODS: Fifty two adult outpatients undergoing upper gastrointestinal tract endoscopy participated in the study. Adipose tissue samples were taken from the abdomen and buttock during the endoscopy procedure and samples from gastric tissue were taken from a subsample of 30 subjects. The presence of Helicobacter pylori was determined using the CLO test. Capillary gas chromatography was used for the extraction of 36 and 42 adipose tissue and gastric mucosa lipids respectively.\nRESULTS: The monounsaturated fatty acids (MUFAs) C18:1n-12c, C16:1n-5, C16:4n-1 and the polyunsaturated fatty acids (PUFAs) C16:3n-4, C20:3n-3, C20:4n-6, C21:5n-3 and C18:2n-9c,12t of the gastric mucosa were present in higher proportions in ulcer negative patients. These unsaturated fatty acids, however, each contributed less than 1% on average to total fatty acid content. In addition, higher average levels of eicosapentaenoic acid (EPA) C20:5n-3 and docosahexaenoic acid (DHA) C22:6n-3 were detected in abdominal and buttock samples in CLO negative controls, compared to CLO positive controls. Adipose tissue and gastric mucosa n-6 and trans fatty acid levels were positively linearly correlated (r = 0.37 and 0.41 for n-6 and trans fatty acids respectively).\nCONCLUSION: Certain minor MUFAs and PUFAs of the gastric mucosa appear to be present in higher proportions in ulcer negative patients. Overall, the findings provide only weak evidence of an association between the gastric mucosal fatty acids and the presence of gastric ulceration. The higher average levels of EPA and DHA in abdominal and buttock adipose tissue in CLO negative controls could be an indicator that dietary FAs inhibit Helicobacter pylori growth. Larger studies are necessary to provide evidence of a biologically relevant effect.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/1471-230x-9-9", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1024942", 
            "issn": [
              "1471-230X"
            ], 
            "name": "BMC Gastroenterology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "9"
          }
        ], 
        "name": "Fatty acid composition of subcutaneous adipose tissue and gastric mucosa: is there a relation with gastric ulceration?", 
        "pagination": "9", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "3097ad48b6999befb7724a9389d9e9d27719de23d98b569053131c6643476133"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "19166613"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "100968547"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/1471-230x-9-9"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1010199446"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/1471-230x-9-9", 
          "https://app.dimensions.ai/details/publication/pub.1010199446"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T19:06", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000503.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1186%2F1471-230X-9-9"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-230x-9-9'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-230x-9-9'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-230x-9-9'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-230x-9-9'


     

    This table displays all metadata directly associated to this object as RDF triples.

    269 TRIPLES      21 PREDICATES      80 URIs      37 LITERALS      25 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/1471-230x-9-9 schema:about N03c3783990624dc0a46e87b3342d2061
    2 N0e95223bb6394703a3034a7a651f2908
    3 N1e660bfc29824c4d8f0d4426cd396822
    4 N3811260e089f49898fdc365b41114eb3
    5 N4470271693d94ab7969fab73ef98ae2a
    6 N521e3ae42fc849c1889162ed755929bc
    7 N57c79a4b69204a239e7147980e7b42d3
    8 N5efe0e3a54d7434bb3504fb95824aa1d
    9 N67929aea7bac4579b110597ed78dbe0c
    10 N67cfbcd82f0143ddbc786486b3955c08
    11 Na0fe859e11af494eab1f358b7981bcbd
    12 Nda4277fe92ff40de8255f34eb6de0f19
    13 Ndf6daef1713c480ca9b05e596121e5a2
    14 Ne19eb0e4fd154b95a3ac185a36d08fa4
    15 Ne2c789bae93b45678faa776c44d29d91
    16 Nf9301b696bd44b9088325b2267c748b3
    17 anzsrc-for:11
    18 anzsrc-for:1103
    19 schema:author N99ef6ddaac644f2d9ac20b602d73ef18
    20 schema:citation sg:pub.10.1046/j.1440-1711.2000.00875.x
    21 https://app.dimensions.ai/details/publication/pub.1074962553
    22 https://app.dimensions.ai/details/publication/pub.1077131635
    23 https://app.dimensions.ai/details/publication/pub.1077235150
    24 https://app.dimensions.ai/details/publication/pub.1079856309
    25 https://app.dimensions.ai/details/publication/pub.1080445796
    26 https://app.dimensions.ai/details/publication/pub.1081970903
    27 https://app.dimensions.ai/details/publication/pub.1083365999
    28 https://doi.org/10.1006/pmed.2001.0930
    29 https://doi.org/10.1016/s0140-6736(02)11030-0
    30 https://doi.org/10.1016/s0140-6736(84)91816-6
    31 https://doi.org/10.1016/s0889-8553(05)70218-1
    32 https://doi.org/10.1021/ac60235a044
    33 https://doi.org/10.1053/j.gastro.2007.11.009
    34 https://doi.org/10.1073/pnas.1635231100
    35 https://doi.org/10.1074/jbc.m011695200
    36 https://doi.org/10.1079/bjn19970171
    37 https://doi.org/10.1079/pns19980078
    38 https://doi.org/10.1084/jem.188.12.2277
    39 https://doi.org/10.1093/acprof:oso/9780195122978.001.0001
    40 https://doi.org/10.1093/ajcn/42.3.560
    41 https://doi.org/10.1093/ajcn/57.1.70
    42 https://doi.org/10.1093/ajcn/76.4.750
    43 https://doi.org/10.1093/oxfordjournals.epirev.a018040
    44 https://doi.org/10.1097/00042737-200110000-00026
    45 https://doi.org/10.1097/00042737-200110000-00027
    46 https://doi.org/10.1097/mog.0b013e3282f02607
    47 https://doi.org/10.1111/j.1365-2036.1988.tb00686.x
    48 https://doi.org/10.1128/iai.69.3.1714-1721.2001
    49 https://doi.org/10.1136/gut.31.9.997
    50 https://doi.org/10.1136/gut.35.11.1557
    51 https://doi.org/10.1136/gut.52.9.1242
    52 https://doi.org/10.1254/jphs.cp0070034
    53 https://doi.org/10.2174/0929867053363478
    54 https://doi.org/10.4067/s0716-97602002000200003
    55 schema:datePublished 2009-12
    56 schema:datePublishedReg 2009-12-01
    57 schema:description BACKGROUND: Both in vitro and epidemiological studies indicate that dietary polyunsaturated fatty acids may play a protective role against peptic ulcer in humans. Adipose tissue fatty acid composition is thought to reflect dietary fatty acid intake. The aim of the present study is to investigate adipose and gastric mucosa fatty acid levels in relation to gastric ulceration status. METHODS: Fifty two adult outpatients undergoing upper gastrointestinal tract endoscopy participated in the study. Adipose tissue samples were taken from the abdomen and buttock during the endoscopy procedure and samples from gastric tissue were taken from a subsample of 30 subjects. The presence of Helicobacter pylori was determined using the CLO test. Capillary gas chromatography was used for the extraction of 36 and 42 adipose tissue and gastric mucosa lipids respectively. RESULTS: The monounsaturated fatty acids (MUFAs) C18:1n-12c, C16:1n-5, C16:4n-1 and the polyunsaturated fatty acids (PUFAs) C16:3n-4, C20:3n-3, C20:4n-6, C21:5n-3 and C18:2n-9c,12t of the gastric mucosa were present in higher proportions in ulcer negative patients. These unsaturated fatty acids, however, each contributed less than 1% on average to total fatty acid content. In addition, higher average levels of eicosapentaenoic acid (EPA) C20:5n-3 and docosahexaenoic acid (DHA) C22:6n-3 were detected in abdominal and buttock samples in CLO negative controls, compared to CLO positive controls. Adipose tissue and gastric mucosa n-6 and trans fatty acid levels were positively linearly correlated (r = 0.37 and 0.41 for n-6 and trans fatty acids respectively). CONCLUSION: Certain minor MUFAs and PUFAs of the gastric mucosa appear to be present in higher proportions in ulcer negative patients. Overall, the findings provide only weak evidence of an association between the gastric mucosal fatty acids and the presence of gastric ulceration. The higher average levels of EPA and DHA in abdominal and buttock adipose tissue in CLO negative controls could be an indicator that dietary FAs inhibit Helicobacter pylori growth. Larger studies are necessary to provide evidence of a biologically relevant effect.
    58 schema:genre research_article
    59 schema:inLanguage en
    60 schema:isAccessibleForFree true
    61 schema:isPartOf N7d2724b5b46743a3855e010c3c870cc6
    62 Ne49eb78e31fe4dbcbd001f10621ae434
    63 sg:journal.1024942
    64 schema:name Fatty acid composition of subcutaneous adipose tissue and gastric mucosa: is there a relation with gastric ulceration?
    65 schema:pagination 9
    66 schema:productId N3a91a0093f6b408abd7331065f4cf446
    67 N3ec30f6ba173492d899c5aecd850974c
    68 N418ce62688f54fa69ceea66a45aa307f
    69 N46681a30f6a945afab345064695415c5
    70 N92e11aedb5c8441ea112e6f3737ca24e
    71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010199446
    72 https://doi.org/10.1186/1471-230x-9-9
    73 schema:sdDatePublished 2019-04-10T19:06
    74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    75 schema:sdPublisher N2cb4f814817a4ca2ba6dce013d53401d
    76 schema:url http://link.springer.com/10.1186%2F1471-230X-9-9
    77 sgo:license sg:explorer/license/
    78 sgo:sdDataset articles
    79 rdf:type schema:ScholarlyArticle
    80 N03c3783990624dc0a46e87b3342d2061 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    81 schema:name Female
    82 rdf:type schema:DefinedTerm
    83 N0e95223bb6394703a3034a7a651f2908 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    84 schema:name Case-Control Studies
    85 rdf:type schema:DefinedTerm
    86 N1e660bfc29824c4d8f0d4426cd396822 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    87 schema:name Humans
    88 rdf:type schema:DefinedTerm
    89 N2cb4f814817a4ca2ba6dce013d53401d schema:name Springer Nature - SN SciGraph project
    90 rdf:type schema:Organization
    91 N3442d62ceaa64abebe4fa191749ba94d rdf:first sg:person.0605456342.96
    92 rdf:rest rdf:nil
    93 N3811260e089f49898fdc365b41114eb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Endoscopy
    95 rdf:type schema:DefinedTerm
    96 N3a91a0093f6b408abd7331065f4cf446 schema:name dimensions_id
    97 schema:value pub.1010199446
    98 rdf:type schema:PropertyValue
    99 N3ec30f6ba173492d899c5aecd850974c schema:name pubmed_id
    100 schema:value 19166613
    101 rdf:type schema:PropertyValue
    102 N418ce62688f54fa69ceea66a45aa307f schema:name doi
    103 schema:value 10.1186/1471-230x-9-9
    104 rdf:type schema:PropertyValue
    105 N4470271693d94ab7969fab73ef98ae2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    106 schema:name Aged
    107 rdf:type schema:DefinedTerm
    108 N46681a30f6a945afab345064695415c5 schema:name readcube_id
    109 schema:value 3097ad48b6999befb7724a9389d9e9d27719de23d98b569053131c6643476133
    110 rdf:type schema:PropertyValue
    111 N521e3ae42fc849c1889162ed755929bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    112 schema:name Male
    113 rdf:type schema:DefinedTerm
    114 N57c79a4b69204a239e7147980e7b42d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Helicobacter pylori
    116 rdf:type schema:DefinedTerm
    117 N5efe0e3a54d7434bb3504fb95824aa1d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Stomach Ulcer
    119 rdf:type schema:DefinedTerm
    120 N67929aea7bac4579b110597ed78dbe0c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Subcutaneous Fat, Abdominal
    122 rdf:type schema:DefinedTerm
    123 N67cfbcd82f0143ddbc786486b3955c08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    124 schema:name Young Adult
    125 rdf:type schema:DefinedTerm
    126 N7d2724b5b46743a3855e010c3c870cc6 schema:issueNumber 1
    127 rdf:type schema:PublicationIssue
    128 N92e11aedb5c8441ea112e6f3737ca24e schema:name nlm_unique_id
    129 schema:value 100968547
    130 rdf:type schema:PropertyValue
    131 N92e6d666ee1a44caaae0bd1c0c2b72be rdf:first sg:person.01022653073.96
    132 rdf:rest Nba3ce4ae7af34ebb96fc86c5a704ba70
    133 N96ea05588bd84e128280a22dc1118a08 rdf:first sg:person.01134776140.81
    134 rdf:rest N92e6d666ee1a44caaae0bd1c0c2b72be
    135 N99ef6ddaac644f2d9ac20b602d73ef18 rdf:first sg:person.01015756304.40
    136 rdf:rest N9c73cc01d1db4082a93c61b157af0008
    137 N9c73cc01d1db4082a93c61b157af0008 rdf:first sg:person.01113231337.54
    138 rdf:rest N96ea05588bd84e128280a22dc1118a08
    139 Na0fe859e11af494eab1f358b7981bcbd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    140 schema:name Adult
    141 rdf:type schema:DefinedTerm
    142 Nba3ce4ae7af34ebb96fc86c5a704ba70 rdf:first sg:person.07563302174.50
    143 rdf:rest N3442d62ceaa64abebe4fa191749ba94d
    144 Nda4277fe92ff40de8255f34eb6de0f19 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    145 schema:name Helicobacter Infections
    146 rdf:type schema:DefinedTerm
    147 Ndf6daef1713c480ca9b05e596121e5a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Buttocks
    149 rdf:type schema:DefinedTerm
    150 Ne19eb0e4fd154b95a3ac185a36d08fa4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    151 schema:name Fatty Acids
    152 rdf:type schema:DefinedTerm
    153 Ne2c789bae93b45678faa776c44d29d91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    154 schema:name Gastric Mucosa
    155 rdf:type schema:DefinedTerm
    156 Ne49eb78e31fe4dbcbd001f10621ae434 schema:volumeNumber 9
    157 rdf:type schema:PublicationVolume
    158 Nf9301b696bd44b9088325b2267c748b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    159 schema:name Middle Aged
    160 rdf:type schema:DefinedTerm
    161 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    162 schema:name Medical and Health Sciences
    163 rdf:type schema:DefinedTerm
    164 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    165 schema:name Clinical Sciences
    166 rdf:type schema:DefinedTerm
    167 sg:journal.1024942 schema:issn 1471-230X
    168 schema:name BMC Gastroenterology
    169 rdf:type schema:Periodical
    170 sg:person.01015756304.40 schema:affiliation https://www.grid.ac/institutes/grid.412481.a
    171 schema:familyName Pagkalos
    172 schema:givenName Vasileios A
    173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015756304.40
    174 rdf:type schema:Person
    175 sg:person.01022653073.96 schema:affiliation https://www.grid.ac/institutes/grid.412481.a
    176 schema:familyName Roussomoustakaki
    177 schema:givenName Maria
    178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022653073.96
    179 rdf:type schema:Person
    180 sg:person.01113231337.54 schema:affiliation https://www.grid.ac/institutes/grid.8127.c
    181 schema:familyName Moschandreas
    182 schema:givenName Joanna
    183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113231337.54
    184 rdf:type schema:Person
    185 sg:person.01134776140.81 schema:affiliation https://www.grid.ac/institutes/grid.8127.c
    186 schema:familyName Kiriakakis
    187 schema:givenName Michael
    188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134776140.81
    189 rdf:type schema:Person
    190 sg:person.0605456342.96 schema:affiliation https://www.grid.ac/institutes/grid.412481.a
    191 schema:familyName Kouroumalis
    192 schema:givenName Elias
    193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605456342.96
    194 rdf:type schema:Person
    195 sg:person.07563302174.50 schema:affiliation https://www.grid.ac/institutes/grid.8127.c
    196 schema:familyName Kafatos
    197 schema:givenName Anthony
    198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07563302174.50
    199 rdf:type schema:Person
    200 sg:pub.10.1046/j.1440-1711.2000.00875.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049182667
    201 https://doi.org/10.1046/j.1440-1711.2000.00875.x
    202 rdf:type schema:CreativeWork
    203 https://app.dimensions.ai/details/publication/pub.1074962553 schema:CreativeWork
    204 https://app.dimensions.ai/details/publication/pub.1077131635 schema:CreativeWork
    205 https://app.dimensions.ai/details/publication/pub.1077235150 schema:CreativeWork
    206 https://app.dimensions.ai/details/publication/pub.1079856309 schema:CreativeWork
    207 https://app.dimensions.ai/details/publication/pub.1080445796 schema:CreativeWork
    208 https://app.dimensions.ai/details/publication/pub.1081970903 schema:CreativeWork
    209 https://app.dimensions.ai/details/publication/pub.1083365999 schema:CreativeWork
    210 https://doi.org/10.1006/pmed.2001.0930 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012916883
    211 rdf:type schema:CreativeWork
    212 https://doi.org/10.1016/s0140-6736(02)11030-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046319386
    213 rdf:type schema:CreativeWork
    214 https://doi.org/10.1016/s0140-6736(84)91816-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014931042
    215 rdf:type schema:CreativeWork
    216 https://doi.org/10.1016/s0889-8553(05)70218-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036619233
    217 rdf:type schema:CreativeWork
    218 https://doi.org/10.1021/ac60235a044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055051243
    219 rdf:type schema:CreativeWork
    220 https://doi.org/10.1053/j.gastro.2007.11.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005806285
    221 rdf:type schema:CreativeWork
    222 https://doi.org/10.1073/pnas.1635231100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027161070
    223 rdf:type schema:CreativeWork
    224 https://doi.org/10.1074/jbc.m011695200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040057826
    225 rdf:type schema:CreativeWork
    226 https://doi.org/10.1079/bjn19970171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021360136
    227 rdf:type schema:CreativeWork
    228 https://doi.org/10.1079/pns19980078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050215823
    229 rdf:type schema:CreativeWork
    230 https://doi.org/10.1084/jem.188.12.2277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020053658
    231 rdf:type schema:CreativeWork
    232 https://doi.org/10.1093/acprof:oso/9780195122978.001.0001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1098760740
    233 rdf:type schema:CreativeWork
    234 https://doi.org/10.1093/ajcn/42.3.560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080094625
    235 rdf:type schema:CreativeWork
    236 https://doi.org/10.1093/ajcn/57.1.70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082798066
    237 rdf:type schema:CreativeWork
    238 https://doi.org/10.1093/ajcn/76.4.750 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075157208
    239 rdf:type schema:CreativeWork
    240 https://doi.org/10.1093/oxfordjournals.epirev.a018040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008722812
    241 rdf:type schema:CreativeWork
    242 https://doi.org/10.1097/00042737-200110000-00026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060297491
    243 rdf:type schema:CreativeWork
    244 https://doi.org/10.1097/00042737-200110000-00027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060297492
    245 rdf:type schema:CreativeWork
    246 https://doi.org/10.1097/mog.0b013e3282f02607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048775336
    247 rdf:type schema:CreativeWork
    248 https://doi.org/10.1111/j.1365-2036.1988.tb00686.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005022645
    249 rdf:type schema:CreativeWork
    250 https://doi.org/10.1128/iai.69.3.1714-1721.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040402521
    251 rdf:type schema:CreativeWork
    252 https://doi.org/10.1136/gut.31.9.997 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024572951
    253 rdf:type schema:CreativeWork
    254 https://doi.org/10.1136/gut.35.11.1557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047829839
    255 rdf:type schema:CreativeWork
    256 https://doi.org/10.1136/gut.52.9.1242 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027639982
    257 rdf:type schema:CreativeWork
    258 https://doi.org/10.1254/jphs.cp0070034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036555531
    259 rdf:type schema:CreativeWork
    260 https://doi.org/10.2174/0929867053363478 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069160453
    261 rdf:type schema:CreativeWork
    262 https://doi.org/10.4067/s0716-97602002000200003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072191682
    263 rdf:type schema:CreativeWork
    264 https://www.grid.ac/institutes/grid.412481.a schema:alternateName University Hospital of Heraklion
    265 schema:name Department of Gastroenterology, University Hospital of Heraklion, Heraklion, Crete, Greece
    266 rdf:type schema:Organization
    267 https://www.grid.ac/institutes/grid.8127.c schema:alternateName University of Crete
    268 schema:name Department of Social Medicine, Preventive Medicine and Nutrition, Medical School, University of Crete, Heraklion, Crete, Greece
    269 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...