Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Cília Mejía-Lancheros, Ramón Estruch, Miguel-Angel Martínez-González, Jordi Salas-Salvadó, Olga Castañer, Dolores Corella, Fernando Arós, Enrique Gómez-Gracia, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Emilio Ros, Javier Díez-Espino, Josep Basora, José-V Sorlí, Rosa-Maria Lamuela-Raventos, Valentina Ruiz-Gutiérrez, Miguel-Ángel Muñoz

ABSTRACT

BACKGROUND: Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population. METHODS: Longitudinal prospective study of 7263 patients (57.5% women), mean age 67.0 (SD 6.2) free from CVD but at high risk, with a median follow-up of 4.8 years (from October 2003 to December 2010). The Hazard Ratios (HRs) of cardiovascular events (myocardial infarction, stroke, and death from cardiovascular causes) related to educational attainment, diagnosed depression (based on medical records), and low social support (number of people living in the household) were estimated by multivariate Cox regression models. RESULTS: Stroke incidence was associated with low educational level in the whole population (HR: 1.83, 95% CI: 1.09-3.09), and especially in men (HR: 2.11, 95% CI 1.09-4.06). Myocardial infarction and CVD mortality were not associated with any of the psychosocial factors considered. CONCLUSION: Adults with low educational level had a higher risk of stroke. Depression and low social support were not associated with CVD incidence. TRIAL REGISTRATION: Clinical trial registration information unique identifier: ISRCTN35739639. More... »

PAGES

135

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1471-2261-14-135

    DOI

    http://dx.doi.org/10.1186/1471-2261-14-135

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1047265634

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25280390


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    413 Department of Family Medicine, Primary Care Division of Seville, San Pablo Health Center, Seville, Spain
    414 Institute of Health Sciences (IUNICS), University of Balearic Islands, and Hospital Son Espases, Palma de Mallorca, Spain
    415 PREDIMED (Prevención con Dieta Mediterránea) Network (RD 06/0045), Instituto de Salud Carlos III, Madrid, Spain
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    419 Instituto de la Grasa, Consejo Superior de Investigaciones Científicas, Sevilla, Spain
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    423 schema:name Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Las Palmas, Spain
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    427 schema:name Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain
    428 Institut Català de la Salut, Barcelona, Spain
    429 Institut d’Investigació en Atenció Primària IDIAP-Jordi Gol, Barcelona, Spain
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    432 schema:name CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain
    433 Department of Preventive Medicine, University of Valencia, Valencia, Spain
    434 PREDIMED (Prevención con Dieta Mediterránea) Network (RD 06/0045), Instituto de Salud Carlos III, Madrid, Spain
    435 Primary Care Division, Valencia Institute of Health, Valencia, Spain
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    437 https://www.grid.ac/institutes/grid.5841.8 schema:alternateName University of Barcelona
    438 schema:name CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain
    439 Department of Internal Medicine of Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    440 Department of Nutrition and Food Science, School of Pharmacy, Xarxa de Referència en Tecnologia dels Aliments, Instituto de Investigación en Nutrición y Seguridad Alimentaria, University of Barcelona, Barcelona, Spain
    441 Lipid Clinic, Department of Endocrinology and Nutrition of Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain
    442 PREDIMED (Prevención con Dieta Mediterránea) Network (RD 06/0045), Instituto de Salud Carlos III, Madrid, Spain
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    445 schema:name Centro de Salud de Tafalla, Servicio Navarro de Salud, University of Navarra, Pamplona, Spain
    446 PREDIMED (Prevención con Dieta Mediterránea) Network (RD 06/0045), Instituto de Salud Carlos III, Madrid, Spain
    447 Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain
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    449 https://www.grid.ac/institutes/grid.7080.f schema:alternateName Autonomous University of Barcelona
    450 schema:name Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain
    451 the PREDIMED Study Investigators, Spain
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