Non coding RNA and brain View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-10-30

AUTHORS

Carlo Presutti, Jessica Rosati, Sara Vincenti, Sergio Nasi

ABSTRACT

Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells, with a wide spectrum of regulatory functions which include RNA modification and regulation of protein synthesis. They have been isolated and characterized in all organisms and tissues, from Archaeobacteria to mammals. In mammalian brain there are a number of these small molecules, which are involved in neuronal differentiation as well as, possibly, in learning and memory. In this manuscript, we analyze the present knowledge about the function of the most important groups of small non-coding RNA present in brain: small nucleolar RNAs, small cytoplasmic RNAs, and microRNAs. The last ones, in particular, appear to be critical for dictating neuronal cell identity during development and to play an important role in neurite growth, synaptic development and neuronal plasticity. More... »

PAGES

s5-s5

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1471-2202-7-s1-s5

    DOI

    http://dx.doi.org/10.1186/1471-2202-7-s1-s5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017462068

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17118159


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