Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-06-13

AUTHORS

Ian R Monk, Pat G Casey, Michael Cronin, Cormac GM Gahan, Colin Hill

ABSTRACT

BACKGROUND: The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to identify and validate genes involved in the pathogenicity and environmental biology of the organism. The aim here was to develop a widely applicable method to tag L. monocytogenes strains, with a particular emphasis on the development of multiple strain competitive index assays. RESULTS: We have constructed a new site-specific integrative vector, pIMC, based on pPL2, for the selection of L. monocytogenes from complex samples. The pIMC vector was further modified through the incorporation of IPTG inducible markers (antibiotic and phenotypic) to produce a suite of four vectors which allowed the discrimination of multiple strains from a single sample. We were able to perform murine infection studies with up to four EGDe isolates within a single mouse and showed that the tags did not impact upon growth rate or virulence. The system also allowed the identification of subtle differences in virulence between strains of L. monocytogenes commonly used in laboratory studies. CONCLUSION: This study has developed a competitive index assay that can be broadly applied to all L. monocytogenes strains. Improved statistical robustness of the data was observed, resulting in fewer mice being required for virulence assays. The competitive index assays provide a powerful method to analyse the virulence or fitness of L. monocytogenes in complex biological samples. More... »

PAGES

96-96

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2180-8-96

DOI

http://dx.doi.org/10.1186/1471-2180-8-96

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036694555

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18554399


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biological Assay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Vectors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Listeria monocytogenes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Listeriosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred BALB C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Virulence", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland", 
          "id": "http://www.grid.ac/institutes/grid.7872.a", 
          "name": [
            "Department of Microbiology, University College Cork, Cork, Ireland", 
            "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Monk", 
        "givenName": "Ian R", 
        "id": "sg:person.01123107001.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123107001.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland", 
          "id": "http://www.grid.ac/institutes/grid.7872.a", 
          "name": [
            "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Casey", 
        "givenName": "Pat G", 
        "id": "sg:person.01250227501.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250227501.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Maths and Statistics, University College Cork, Cork, Ireland", 
          "id": "http://www.grid.ac/institutes/grid.7872.a", 
          "name": [
            "Department of Maths and Statistics, University College Cork, Cork, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cronin", 
        "givenName": "Michael", 
        "id": "sg:person.0735450112.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735450112.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmacy, University College Cork, Cork, Ireland", 
          "id": "http://www.grid.ac/institutes/grid.7872.a", 
          "name": [
            "Department of Microbiology, University College Cork, Cork, Ireland", 
            "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland", 
            "Department of Pharmacy, University College Cork, Cork, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gahan", 
        "givenName": "Cormac GM", 
        "id": "sg:person.014255126037.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014255126037.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland", 
          "id": "http://www.grid.ac/institutes/grid.7872.a", 
          "name": [
            "Department of Microbiology, University College Cork, Cork, Ireland", 
            "Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hill", 
        "givenName": "Colin", 
        "id": "sg:person.01202224511.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202224511.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00253-005-0107-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028972103", 
          "https://doi.org/10.1007/s00253-005-0107-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2180-6-86", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049849609", 
          "https://doi.org/10.1186/1471-2180-6-86"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrmicro799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036425897", 
          "https://doi.org/10.1038/nrmicro799"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-06-13", 
    "datePublishedReg": "2008-06-13", 
    "description": "BACKGROUND: The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to identify and validate genes involved in the pathogenicity and environmental biology of the organism. The aim here was to develop a widely applicable method to tag L. monocytogenes strains, with a particular emphasis on the development of multiple strain competitive index assays.\nRESULTS: We have constructed a new site-specific integrative vector, pIMC, based on pPL2, for the selection of L. monocytogenes from complex samples. The pIMC vector was further modified through the incorporation of IPTG inducible markers (antibiotic and phenotypic) to produce a suite of four vectors which allowed the discrimination of multiple strains from a single sample. We were able to perform murine infection studies with up to four EGDe isolates within a single mouse and showed that the tags did not impact upon growth rate or virulence. The system also allowed the identification of subtle differences in virulence between strains of L. monocytogenes commonly used in laboratory studies.\nCONCLUSION: This study has developed a competitive index assay that can be broadly applied to all L. monocytogenes strains. Improved statistical robustness of the data was observed, resulting in fewer mice being required for virulence assays. The competitive index assays provide a powerful method to analyse the virulence or fitness of L. monocytogenes in complex biological samples.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/1471-2180-8-96", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024253", 
        "issn": [
          "1471-2180"
        ], 
        "name": "BMC Microbiology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "keywords": [
      "integrative vector", 
      "post-genomic era", 
      "competitive index assays", 
      "genomic era", 
      "environmental biology", 
      "virulence assays", 
      "complex biological samples", 
      "Murine infection studies", 
      "virulence", 
      "Listeria monocytogenes", 
      "competitive index", 
      "multiple strains", 
      "infection studies", 
      "inducible marker", 
      "growth rate", 
      "assays", 
      "single mouse", 
      "subtle differences", 
      "PPL2", 
      "positive pathogens", 
      "genes", 
      "monocytogenes", 
      "biology", 
      "organisms", 
      "strains", 
      "powerful method", 
      "biological samples", 
      "pathogenicity", 
      "fitness", 
      "vector", 
      "pathogens", 
      "complex samples", 
      "mice", 
      "lethal infection", 
      "tags", 
      "isolates", 
      "single sample", 
      "statistical robustness", 
      "identification", 
      "markers", 
      "applicable method", 
      "development", 
      "laboratory studies", 
      "selection", 
      "particular emphasis", 
      "foodborne", 
      "suite", 
      "study", 
      "incorporation", 
      "individuals", 
      "infection", 
      "samples", 
      "differences", 
      "discrimination", 
      "data", 
      "rate", 
      "system", 
      "emphasis", 
      "research", 
      "method", 
      "era", 
      "index", 
      "aim", 
      "technique", 
      "robustness", 
      "PIMC", 
      "monocytogenes research", 
      "tag L. monocytogenes", 
      "L. monocytogenes", 
      "index assays", 
      "new site-specific integrative vector", 
      "site-specific integrative vector", 
      "pIMC vector", 
      "IPTG inducible markers", 
      "EGDe isolates"
    ], 
    "name": "Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector", 
    "pagination": "96-96", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036694555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2180-8-96"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18554399"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2180-8-96", 
      "https://app.dimensions.ai/details/publication/pub.1036694555"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_468.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/1471-2180-8-96"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2180-8-96'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2180-8-96'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2180-8-96'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2180-8-96'


 

This table displays all metadata directly associated to this object as RDF triples.

217 TRIPLES      22 PREDICATES      113 URIs      102 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2180-8-96 schema:about N0212adda81b74a21abba4663f8736576
2 N3449b1345ea640d5830fa8491d95dccb
3 N5198418c31d24856ba4c1c2afc1ed7bb
4 N54da6955713a454d94a3404303f8217e
5 N5930b14519bf43d3a983ed4e2bd97510
6 N824e8a1ba835476faba0310a5e32839d
7 N917c65c6da5343f1ae9ef96ab75592d5
8 Na35dc95d4b804a7ea34e3ac030c3d2a2
9 Nefe014f5c9c64f278b847cc0c4b3d7cd
10 anzsrc-for:11
11 anzsrc-for:1108
12 schema:author N9d4786600f8941eca52e36e81f199218
13 schema:citation sg:pub.10.1007/s00253-005-0107-6
14 sg:pub.10.1038/nrmicro799
15 sg:pub.10.1186/1471-2180-6-86
16 schema:datePublished 2008-06-13
17 schema:datePublishedReg 2008-06-13
18 schema:description BACKGROUND: The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to identify and validate genes involved in the pathogenicity and environmental biology of the organism. The aim here was to develop a widely applicable method to tag L. monocytogenes strains, with a particular emphasis on the development of multiple strain competitive index assays. RESULTS: We have constructed a new site-specific integrative vector, pIMC, based on pPL2, for the selection of L. monocytogenes from complex samples. The pIMC vector was further modified through the incorporation of IPTG inducible markers (antibiotic and phenotypic) to produce a suite of four vectors which allowed the discrimination of multiple strains from a single sample. We were able to perform murine infection studies with up to four EGDe isolates within a single mouse and showed that the tags did not impact upon growth rate or virulence. The system also allowed the identification of subtle differences in virulence between strains of L. monocytogenes commonly used in laboratory studies. CONCLUSION: This study has developed a competitive index assay that can be broadly applied to all L. monocytogenes strains. Improved statistical robustness of the data was observed, resulting in fewer mice being required for virulence assays. The competitive index assays provide a powerful method to analyse the virulence or fitness of L. monocytogenes in complex biological samples.
19 schema:genre article
20 schema:inLanguage en
21 schema:isAccessibleForFree true
22 schema:isPartOf N6317329e22ea4ee1b403664278686ab3
23 Na11fe4cc91934a3886645066e7f60ed5
24 sg:journal.1024253
25 schema:keywords EGDe isolates
26 IPTG inducible markers
27 L. monocytogenes
28 Listeria monocytogenes
29 Murine infection studies
30 PIMC
31 PPL2
32 aim
33 applicable method
34 assays
35 biological samples
36 biology
37 competitive index
38 competitive index assays
39 complex biological samples
40 complex samples
41 data
42 development
43 differences
44 discrimination
45 emphasis
46 environmental biology
47 era
48 fitness
49 foodborne
50 genes
51 genomic era
52 growth rate
53 identification
54 incorporation
55 index
56 index assays
57 individuals
58 inducible marker
59 infection
60 infection studies
61 integrative vector
62 isolates
63 laboratory studies
64 lethal infection
65 markers
66 method
67 mice
68 monocytogenes
69 monocytogenes research
70 multiple strains
71 new site-specific integrative vector
72 organisms
73 pIMC vector
74 particular emphasis
75 pathogenicity
76 pathogens
77 positive pathogens
78 post-genomic era
79 powerful method
80 rate
81 research
82 robustness
83 samples
84 selection
85 single mouse
86 single sample
87 site-specific integrative vector
88 statistical robustness
89 strains
90 study
91 subtle differences
92 suite
93 system
94 tag L. monocytogenes
95 tags
96 technique
97 vector
98 virulence
99 virulence assays
100 schema:name Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector
101 schema:pagination 96-96
102 schema:productId N29ee2394bef6432a967d8e20c9536b9d
103 N6ff0802548794194b6f683d41e03a7f6
104 N7efadcb7f9564eb6a8db593f489a9e2c
105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036694555
106 https://doi.org/10.1186/1471-2180-8-96
107 schema:sdDatePublished 2021-11-01T18:11
108 schema:sdLicense https://scigraph.springernature.com/explorer/license/
109 schema:sdPublisher N9f0d72de235b4a6cbf0af809bc60b7b2
110 schema:url https://doi.org/10.1186/1471-2180-8-96
111 sgo:license sg:explorer/license/
112 sgo:sdDataset articles
113 rdf:type schema:ScholarlyArticle
114 N0212adda81b74a21abba4663f8736576 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Listeria monocytogenes
116 rdf:type schema:DefinedTerm
117 N220e3a2bb43f479281c25fc6f3c4b141 rdf:first sg:person.014255126037.78
118 rdf:rest Nadf323fb73524e1bade479cfc5a1af33
119 N29ee2394bef6432a967d8e20c9536b9d schema:name pubmed_id
120 schema:value 18554399
121 rdf:type schema:PropertyValue
122 N3449b1345ea640d5830fa8491d95dccb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Mice, Inbred BALB C
124 rdf:type schema:DefinedTerm
125 N5198418c31d24856ba4c1c2afc1ed7bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Female
127 rdf:type schema:DefinedTerm
128 N54da6955713a454d94a3404303f8217e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Genetic Vectors
130 rdf:type schema:DefinedTerm
131 N5930b14519bf43d3a983ed4e2bd97510 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Virulence
133 rdf:type schema:DefinedTerm
134 N6317329e22ea4ee1b403664278686ab3 schema:volumeNumber 8
135 rdf:type schema:PublicationVolume
136 N6ac39869379c468f85a81c4c9644b44e rdf:first sg:person.0735450112.28
137 rdf:rest N220e3a2bb43f479281c25fc6f3c4b141
138 N6ff0802548794194b6f683d41e03a7f6 schema:name dimensions_id
139 schema:value pub.1036694555
140 rdf:type schema:PropertyValue
141 N7efadcb7f9564eb6a8db593f489a9e2c schema:name doi
142 schema:value 10.1186/1471-2180-8-96
143 rdf:type schema:PropertyValue
144 N824e8a1ba835476faba0310a5e32839d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Biological Assay
146 rdf:type schema:DefinedTerm
147 N917c65c6da5343f1ae9ef96ab75592d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Animals
149 rdf:type schema:DefinedTerm
150 N9d4786600f8941eca52e36e81f199218 rdf:first sg:person.01123107001.25
151 rdf:rest Ne9ef80f73e4d40e19476165000f42a08
152 N9f0d72de235b4a6cbf0af809bc60b7b2 schema:name Springer Nature - SN SciGraph project
153 rdf:type schema:Organization
154 Na11fe4cc91934a3886645066e7f60ed5 schema:issueNumber 1
155 rdf:type schema:PublicationIssue
156 Na35dc95d4b804a7ea34e3ac030c3d2a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Listeriosis
158 rdf:type schema:DefinedTerm
159 Nadf323fb73524e1bade479cfc5a1af33 rdf:first sg:person.01202224511.99
160 rdf:rest rdf:nil
161 Ne9ef80f73e4d40e19476165000f42a08 rdf:first sg:person.01250227501.85
162 rdf:rest N6ac39869379c468f85a81c4c9644b44e
163 Nefe014f5c9c64f278b847cc0c4b3d7cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Mice
165 rdf:type schema:DefinedTerm
166 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
167 schema:name Medical and Health Sciences
168 rdf:type schema:DefinedTerm
169 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
170 schema:name Medical Microbiology
171 rdf:type schema:DefinedTerm
172 sg:journal.1024253 schema:issn 1471-2180
173 schema:name BMC Microbiology
174 schema:publisher Springer Nature
175 rdf:type schema:Periodical
176 sg:person.01123107001.25 schema:affiliation grid-institutes:grid.7872.a
177 schema:familyName Monk
178 schema:givenName Ian R
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123107001.25
180 rdf:type schema:Person
181 sg:person.01202224511.99 schema:affiliation grid-institutes:grid.7872.a
182 schema:familyName Hill
183 schema:givenName Colin
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202224511.99
185 rdf:type schema:Person
186 sg:person.01250227501.85 schema:affiliation grid-institutes:grid.7872.a
187 schema:familyName Casey
188 schema:givenName Pat G
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250227501.85
190 rdf:type schema:Person
191 sg:person.014255126037.78 schema:affiliation grid-institutes:grid.7872.a
192 schema:familyName Gahan
193 schema:givenName Cormac GM
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014255126037.78
195 rdf:type schema:Person
196 sg:person.0735450112.28 schema:affiliation grid-institutes:grid.7872.a
197 schema:familyName Cronin
198 schema:givenName Michael
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735450112.28
200 rdf:type schema:Person
201 sg:pub.10.1007/s00253-005-0107-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028972103
202 https://doi.org/10.1007/s00253-005-0107-6
203 rdf:type schema:CreativeWork
204 sg:pub.10.1038/nrmicro799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036425897
205 https://doi.org/10.1038/nrmicro799
206 rdf:type schema:CreativeWork
207 sg:pub.10.1186/1471-2180-6-86 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049849609
208 https://doi.org/10.1186/1471-2180-6-86
209 rdf:type schema:CreativeWork
210 grid-institutes:grid.7872.a schema:alternateName Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
211 Department of Maths and Statistics, University College Cork, Cork, Ireland
212 Department of Pharmacy, University College Cork, Cork, Ireland
213 schema:name Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
214 Department of Maths and Statistics, University College Cork, Cork, Ireland
215 Department of Microbiology, University College Cork, Cork, Ireland
216 Department of Pharmacy, University College Cork, Cork, Ireland
217 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...