JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacterial Load", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colostrum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunization, Passive", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoglobulin A, Secretory", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred BALB C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mycobacterium tuberculosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tuberculosis, Pulmonary", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alvarez", 
        "givenName": "Nadine", 
        "id": "sg:person.0635412132.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635412132.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Otero", 
        "givenName": "Oscar", 
        "id": "sg:person.01243761132.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243761132.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Camacho", 
        "givenName": "Frank", 
        "id": "sg:person.0751640532.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751640532.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Borrero", 
        "givenName": "Reinier", 
        "id": "sg:person.01013304132.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013304132.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tirado", 
        "givenName": "Yanely", 
        "id": "sg:person.01066067132.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066067132.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Puig", 
        "givenName": "Alina", 
        "id": "sg:person.01134202332.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134202332.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aguilar", 
        "givenName": "Alicia", 
        "id": "sg:person.01202315532.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202315532.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e0n\u201d, D.F. Mexico. CP 14 000", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e0n\u201d, D.F. Mexico. CP 14 000"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rivas", 
        "givenName": "Cesar", 
        "id": "sg:person.01250430732.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250430732.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e0n\u201d, D.F. Mexico. CP 14 000", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e0n\u201d, D.F. Mexico. CP 14 000"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cervantes", 
        "givenName": "Axel", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Falero-D\u00edaz", 
        "givenName": "Gustavo", 
        "id": "sg:person.01336642362.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336642362.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Enterprise of Production of Serum and Hemoderivates \u201cAdalberto Pesant Gonz\u00e1lez\u201d. Ave 51 No.33 235 km 19 medio \u00bd. Arroyo Arenas, La Lisa. Ciudad de la Habana, Cuba. CP 13400", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Enterprise of Production of Serum and Hemoderivates \u201cAdalberto Pesant Gonz\u00e1lez\u201d. Ave 51 No.33 235 km 19 medio \u00bd. Arroyo Arenas, La Lisa. Ciudad de la Habana, Cuba. CP 13400"
          ], 
          "type": "Organization"
        }, 
        "familyName": "C\u00e1diz", 
        "givenName": "Armando", 
        "id": "sg:person.0751756442.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751756442.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sarmiento", 
        "givenName": "Mar\u00eda E", 
        "id": "sg:person.0741327632.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741327632.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 16150 Kubang Kerian, Malaysia", 
          "id": "http://www.grid.ac/institutes/grid.11875.3a", 
          "name": [
            "School of Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Malaysia", 
            "Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 16150 Kubang Kerian, Malaysia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Norazmi", 
        "givenName": "Mohd Nor", 
        "id": "sg:person.0751725370.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751725370.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e0n\u201d, D.F. Mexico. CP 14 000", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e0n\u201d, D.F. Mexico. CP 14 000"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hern\u00e1ndez-Pando", 
        "givenName": "Rogelio", 
        "id": "sg:person.01176732673.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176732673.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Molecular Biology. Finlay Institute. Center of Research \u2013 Producction of Vaccines. Ave. 27 No. 19805, La Lisa. Ciudad de la Habana, Cuba. AP. 16017, CP 11600"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Acosta", 
        "givenName": "Armando", 
        "id": "sg:person.0707504342.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707504342.50"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2013-02-25", 
    "datePublishedReg": "2013-02-25", 
    "description": "BACKGROUND: Immunoglobulin A is the most abundant isotype in secretions from mucosal surfaces of the gastrointestinal, respiratory and genitourinary tracts and in external secretions such as colostrum, breast milk, tears and saliva. The high concentration of human secretory IgA (hsIgA) in human colostrum strongly suggests that it should play an important role in the passive immune protection against gastrointestinal and respiratory infections.\nMATERIALS AND METHODS: Human secretory IgA was purified from colostrum. The reactivity of hsIgA against mycobacterial antigens and its protective capacity against mycobacterial infection was evaluated.\nRESULTS: The passive administration of hsIgA reduces the pneumonic area before challenge with M. tuberculosis. The intratracheal administration of M. tuberculosis preincubated with hsIgA to mice greatly reduced the bacterial load in the lungs and diminished lung tissue injury.\nCONCLUSIONS: HsIgA purified from colostrum protects against M. tuberculosis infection in an experimental mouse model.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/1471-2172-14-s1-s3", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024252", 
        "issn": [
          "1471-2172"
        ], 
        "name": "BMC Immunology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "Suppl 1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "14"
      }
    ], 
    "keywords": [
      "secretory IgA", 
      "human secretory IgA", 
      "passive administration", 
      "human colostrum", 
      "passive immune protection", 
      "progressive pulmonary infection", 
      "lung tissue injury", 
      "experimental mouse model", 
      "respiratory infections", 
      "pulmonary infection", 
      "tuberculosis infection", 
      "pneumonic areas", 
      "breast milk", 
      "intratracheal administration", 
      "genitourinary tract", 
      "immune protection", 
      "mycobacterial antigens", 
      "mycobacterial infection", 
      "tissue injury", 
      "immunoglobulin A", 
      "murine model", 
      "mouse model", 
      "mucosal surfaces", 
      "infection", 
      "IgA", 
      "bacterial load", 
      "external secretions", 
      "Mycobacterium tuberculosis", 
      "protective capacity", 
      "tuberculosis", 
      "abundant isotype", 
      "colostrum", 
      "administration", 
      "secretion", 
      "lung", 
      "injury", 
      "antigen", 
      "mice", 
      "protects", 
      "tract", 
      "tears", 
      "important role", 
      "high concentrations", 
      "isotypes", 
      "saliva", 
      "protection", 
      "milk", 
      "role", 
      "reactivity", 
      "concentration", 
      "area", 
      "capacity", 
      "challenges", 
      "model", 
      "method", 
      "materials", 
      "load", 
      "surface", 
      "reactivity of hsIgA", 
      "hsIgA", 
      "colostrum protects"
    ], 
    "name": "Passive administration of purified secretory IgA from human colostrum induces protection against Mycobacterium tuberculosis in a murine model of progressive pulmonary infection", 
    "pagination": "s3-s3", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1047750398"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2172-14-s1-s3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23458564"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2172-14-s1-s3", 
      "https://app.dimensions.ai/details/publication/pub.1047750398"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_607.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/1471-2172-14-s1-s3"
  }
]

Download the RDF metadata as:  json-ld nt turtle xml License info

This table displays all metadata directly associated to this object as RDF triples.

275 TRIPLES      21 PREDICATES      99 URIs      91 LITERALS      19 BLANK NODES