Use of tiling array data and RNA secondary structure predictions to identify noncoding RNA genes View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2007-12

AUTHORS

Christian Weile, Paul P Gardner, Mads M Hedegaard, Jeppe Vinther

ABSTRACT

BACKGROUND: Within the last decade a large number of noncoding RNA genes have been identified, but this may only be the tip of the iceberg. Using comparative genomics a large number of sequences that have signals concordant with conserved RNA secondary structures have been discovered in the human genome. Moreover, genome wide transcription profiling with tiling arrays indicate that the majority of the genome is transcribed. RESULTS: We have combined tiling array data with genome wide structural RNA predictions to search for novel noncoding and structural RNA genes that are expressed in the human neuroblastoma cell line SK-N-AS. Using this strategy, we identify thousands of human candidate RNA genes. To further verify the expression of these genes, we focused on candidate genes that had a stable hairpin structures or a high level of covariance. Using northern blotting, we verify the expression of 2 out of 3 of the hairpin structures and 3 out of 9 high covariance structures in SK-N-AS cells. CONCLUSION: Our results demonstrate that many human noncoding, structured and conserved RNA genes remain to be discovered and that tissue specific tiling array data can be used in combination with computational predictions of sequences encoding structural RNAs to improve the search for such genes. More... »

PAGES

244

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2164-8-244

DOI

http://dx.doi.org/10.1186/1471-2164-8-244

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034768644

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17645787


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Algorithms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nucleic Acid Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligonucleotide Array Sequence Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Untranslated", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, RNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Homology, Nucleic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Copenhagen", 
          "id": "https://www.grid.ac/institutes/grid.5254.6", 
          "name": [
            "Molecular Evolution Group, Department of Molecular Biology, University of Copenhagen, Ole Maal\u00f8es Vej 5, Building 4.1.27, DK-2200, Copenhagen N, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Weile", 
        "givenName": "Christian", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Copenhagen", 
          "id": "https://www.grid.ac/institutes/grid.5254.6", 
          "name": [
            "Molecular Evolution Group, Department of Molecular Biology, University of Copenhagen, Ole Maal\u00f8es Vej 5, Building 4.1.27, DK-2200, Copenhagen N, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gardner", 
        "givenName": "Paul P", 
        "id": "sg:person.01224632205.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224632205.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Copenhagen", 
          "id": "https://www.grid.ac/institutes/grid.5254.6", 
          "name": [
            "Molecular Evolution Group, Department of Molecular Biology, University of Copenhagen, Ole Maal\u00f8es Vej 5, Building 4.1.27, DK-2200, Copenhagen N, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hedegaard", 
        "givenName": "Mads M", 
        "id": "sg:person.01071022405.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071022405.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Copenhagen", 
          "id": "https://www.grid.ac/institutes/grid.5254.6", 
          "name": [
            "Molecular Evolution Group, Department of Molecular Biology, University of Copenhagen, Ole Maal\u00f8es Vej 5, Building 4.1.27, DK-2200, Copenhagen N, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vinther", 
        "givenName": "Jeppe", 
        "id": "sg:person.0602700267.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602700267.90"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1101/gr.3455305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005251190"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-6-241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005448112", 
          "https://doi.org/10.1186/1471-2105-6-241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gki541", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008319008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(02)00308-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013627034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013684976", 
          "https://doi.org/10.1038/nrg1321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013684976", 
          "https://doi.org/10.1038/nrg1321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-7-239", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015800611", 
          "https://doi.org/10.1186/1471-2105-7-239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0409169102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016701541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2004.12.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017459887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0511155103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020588539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1098119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022514256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkj002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023486309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1932072100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024489496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkj135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024707863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2164-6-104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027055001", 
          "https://doi.org/10.1186/1471-2164-6-104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.1933104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028112195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.5650707", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028375537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028917438", 
          "https://doi.org/10.1038/nbt1144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028917438", 
          "https://doi.org/10.1038/nbt1144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028917438", 
          "https://doi.org/10.1038/nbt1144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkj112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036093015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1261/rna.2322506", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036696023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature05113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037216489", 
          "https://doi.org/10.1038/nature05113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature05113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037216489", 
          "https://doi.org/10.1038/nature05113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature05113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037216489", 
          "https://doi.org/10.1038/nature05113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gki025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038073766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkh103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040312195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.4200206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043481930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.4624306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043516206"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-2-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046362248", 
          "https://doi.org/10.1186/1471-2105-2-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1108625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046921907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.3715005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048048079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03441", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050742226", 
          "https://doi.org/10.1038/nature03441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03441", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050742226", 
          "https://doi.org/10.1038/nature03441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.5159906", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050807485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pcbi.0020005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052454746"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pcbi.0020005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052454746"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1112014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052847323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkj133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053168823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pcbi.0020033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053214791"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2007-12", 
    "datePublishedReg": "2007-12-01", 
    "description": "BACKGROUND: Within the last decade a large number of noncoding RNA genes have been identified, but this may only be the tip of the iceberg. Using comparative genomics a large number of sequences that have signals concordant with conserved RNA secondary structures have been discovered in the human genome. Moreover, genome wide transcription profiling with tiling arrays indicate that the majority of the genome is transcribed.\nRESULTS: We have combined tiling array data with genome wide structural RNA predictions to search for novel noncoding and structural RNA genes that are expressed in the human neuroblastoma cell line SK-N-AS. Using this strategy, we identify thousands of human candidate RNA genes. To further verify the expression of these genes, we focused on candidate genes that had a stable hairpin structures or a high level of covariance. Using northern blotting, we verify the expression of 2 out of 3 of the hairpin structures and 3 out of 9 high covariance structures in SK-N-AS cells.\nCONCLUSION: Our results demonstrate that many human noncoding, structured and conserved RNA genes remain to be discovered and that tissue specific tiling array data can be used in combination with computational predictions of sequences encoding structural RNAs to improve the search for such genes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2164-8-244", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1023790", 
        "issn": [
          "1471-2164"
        ], 
        "name": "BMC Genomics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Use of tiling array data and RNA secondary structure predictions to identify noncoding RNA genes", 
    "pagination": "244", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a59fc77334c0f8905a80838edefec6381ec73575c44dba9a1e3f5b4eab7a4a02"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17645787"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100965258"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2164-8-244"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034768644"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2164-8-244", 
      "https://app.dimensions.ai/details/publication/pub.1034768644"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000506.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2164-8-244"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-8-244'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-8-244'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-8-244'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-8-244'


 

This table displays all metadata directly associated to this object as RDF triples.

235 TRIPLES      21 PREDICATES      72 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2164-8-244 schema:about N0113919f30ee42fc88c88697ee45b0d4
2 N074730046a3c43649b907b476ec6f828
3 N115c4fd31f4648de91c3b5cc7f972e11
4 N7cff4b22df8b464f8985cdfdfb740651
5 N80b46ef106bd4e7ab51f6443f625910a
6 N9452cdb3dbf84f9c85b4adf7f24389ea
7 Na52b21e15f2a454bbb7de55fd7fb9f8d
8 Na687a198e2ce432fbe330eb0e5191ee2
9 Nd5e23b9fb2cd4b17b8eff607718c5f7a
10 Ne1987b722c954c7b87dc901e9b03f5a0
11 anzsrc-for:06
12 anzsrc-for:0604
13 schema:author Nd60916ded0404902bb535d7b416d26f1
14 schema:citation sg:pub.10.1038/nature03441
15 sg:pub.10.1038/nature05113
16 sg:pub.10.1038/nbt1144
17 sg:pub.10.1038/nrg1321
18 sg:pub.10.1186/1471-2105-2-8
19 sg:pub.10.1186/1471-2105-6-241
20 sg:pub.10.1186/1471-2105-7-239
21 sg:pub.10.1186/1471-2164-6-104
22 https://doi.org/10.1016/j.cell.2004.12.031
23 https://doi.org/10.1016/s0022-2836(02)00308-x
24 https://doi.org/10.1073/pnas.0409169102
25 https://doi.org/10.1073/pnas.0511155103
26 https://doi.org/10.1073/pnas.1932072100
27 https://doi.org/10.1093/nar/gkh103
28 https://doi.org/10.1093/nar/gki025
29 https://doi.org/10.1093/nar/gki541
30 https://doi.org/10.1093/nar/gkj002
31 https://doi.org/10.1093/nar/gkj112
32 https://doi.org/10.1093/nar/gkj133
33 https://doi.org/10.1093/nar/gkj135
34 https://doi.org/10.1101/gr.1933104
35 https://doi.org/10.1101/gr.3455305
36 https://doi.org/10.1101/gr.3715005
37 https://doi.org/10.1101/gr.4200206
38 https://doi.org/10.1101/gr.4624306
39 https://doi.org/10.1101/gr.5159906
40 https://doi.org/10.1101/gr.5650707
41 https://doi.org/10.1126/science.1098119
42 https://doi.org/10.1126/science.1108625
43 https://doi.org/10.1126/science.1112014
44 https://doi.org/10.1261/rna.2322506
45 https://doi.org/10.1371/journal.pcbi.0020005
46 https://doi.org/10.1371/journal.pcbi.0020033
47 schema:datePublished 2007-12
48 schema:datePublishedReg 2007-12-01
49 schema:description BACKGROUND: Within the last decade a large number of noncoding RNA genes have been identified, but this may only be the tip of the iceberg. Using comparative genomics a large number of sequences that have signals concordant with conserved RNA secondary structures have been discovered in the human genome. Moreover, genome wide transcription profiling with tiling arrays indicate that the majority of the genome is transcribed. RESULTS: We have combined tiling array data with genome wide structural RNA predictions to search for novel noncoding and structural RNA genes that are expressed in the human neuroblastoma cell line SK-N-AS. Using this strategy, we identify thousands of human candidate RNA genes. To further verify the expression of these genes, we focused on candidate genes that had a stable hairpin structures or a high level of covariance. Using northern blotting, we verify the expression of 2 out of 3 of the hairpin structures and 3 out of 9 high covariance structures in SK-N-AS cells. CONCLUSION: Our results demonstrate that many human noncoding, structured and conserved RNA genes remain to be discovered and that tissue specific tiling array data can be used in combination with computational predictions of sequences encoding structural RNAs to improve the search for such genes.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree true
53 schema:isPartOf N5cb6e444058443e6b4f05a03349a4535
54 Nce8c772a22174144994500a6ea972d4d
55 sg:journal.1023790
56 schema:name Use of tiling array data and RNA secondary structure predictions to identify noncoding RNA genes
57 schema:pagination 244
58 schema:productId N5975e5bc58834017b974ddc7e6c85653
59 N79b776573d014cbcafd0f0ea0509289b
60 N94676db9384e46bc8e504f534ddb190a
61 Nad5eba4bd60840d9b9fb0b070a959aed
62 Nc80a71e319854500b0a633f4e0b4b0b0
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034768644
64 https://doi.org/10.1186/1471-2164-8-244
65 schema:sdDatePublished 2019-04-10T22:30
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N4f24dff318624c2a932d5218a004faba
68 schema:url http://link.springer.com/10.1186%2F1471-2164-8-244
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N0113919f30ee42fc88c88697ee45b0d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name RNA, Untranslated
74 rdf:type schema:DefinedTerm
75 N074730046a3c43649b907b476ec6f828 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Sequence Homology, Nucleic Acid
77 rdf:type schema:DefinedTerm
78 N115c4fd31f4648de91c3b5cc7f972e11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Base Sequence
80 rdf:type schema:DefinedTerm
81 N4f24dff318624c2a932d5218a004faba schema:name Springer Nature - SN SciGraph project
82 rdf:type schema:Organization
83 N5223f5d18d9949cf86aebed9f5df1c9c schema:affiliation https://www.grid.ac/institutes/grid.5254.6
84 schema:familyName Weile
85 schema:givenName Christian
86 rdf:type schema:Person
87 N5975e5bc58834017b974ddc7e6c85653 schema:name nlm_unique_id
88 schema:value 100965258
89 rdf:type schema:PropertyValue
90 N5cb6e444058443e6b4f05a03349a4535 schema:volumeNumber 8
91 rdf:type schema:PublicationVolume
92 N64925904fdc240bc831035c043b694ad rdf:first sg:person.0602700267.90
93 rdf:rest rdf:nil
94 N79b776573d014cbcafd0f0ea0509289b schema:name readcube_id
95 schema:value a59fc77334c0f8905a80838edefec6381ec73575c44dba9a1e3f5b4eab7a4a02
96 rdf:type schema:PropertyValue
97 N7cff4b22df8b464f8985cdfdfb740651 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Nucleic Acid Conformation
99 rdf:type schema:DefinedTerm
100 N80b46ef106bd4e7ab51f6443f625910a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Tumor Cells, Cultured
102 rdf:type schema:DefinedTerm
103 N9452cdb3dbf84f9c85b4adf7f24389ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Humans
105 rdf:type schema:DefinedTerm
106 N94676db9384e46bc8e504f534ddb190a schema:name doi
107 schema:value 10.1186/1471-2164-8-244
108 rdf:type schema:PropertyValue
109 Na52b21e15f2a454bbb7de55fd7fb9f8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Molecular Sequence Data
111 rdf:type schema:DefinedTerm
112 Na687a198e2ce432fbe330eb0e5191ee2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Algorithms
114 rdf:type schema:DefinedTerm
115 Nad5eba4bd60840d9b9fb0b070a959aed schema:name dimensions_id
116 schema:value pub.1034768644
117 rdf:type schema:PropertyValue
118 Nc6fd87475b404cbeb6ebeb322728985a rdf:first sg:person.01071022405.20
119 rdf:rest N64925904fdc240bc831035c043b694ad
120 Nc80a71e319854500b0a633f4e0b4b0b0 schema:name pubmed_id
121 schema:value 17645787
122 rdf:type schema:PropertyValue
123 Nce8c772a22174144994500a6ea972d4d schema:issueNumber 1
124 rdf:type schema:PublicationIssue
125 Nd5e23b9fb2cd4b17b8eff607718c5f7a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Oligonucleotide Array Sequence Analysis
127 rdf:type schema:DefinedTerm
128 Nd60916ded0404902bb535d7b416d26f1 rdf:first N5223f5d18d9949cf86aebed9f5df1c9c
129 rdf:rest Nef68f044ad3643d5a331e45b779e8c71
130 Ne1987b722c954c7b87dc901e9b03f5a0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Sequence Analysis, RNA
132 rdf:type schema:DefinedTerm
133 Nef68f044ad3643d5a331e45b779e8c71 rdf:first sg:person.01224632205.56
134 rdf:rest Nc6fd87475b404cbeb6ebeb322728985a
135 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
136 schema:name Biological Sciences
137 rdf:type schema:DefinedTerm
138 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
139 schema:name Genetics
140 rdf:type schema:DefinedTerm
141 sg:journal.1023790 schema:issn 1471-2164
142 schema:name BMC Genomics
143 rdf:type schema:Periodical
144 sg:person.01071022405.20 schema:affiliation https://www.grid.ac/institutes/grid.5254.6
145 schema:familyName Hedegaard
146 schema:givenName Mads M
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071022405.20
148 rdf:type schema:Person
149 sg:person.01224632205.56 schema:affiliation https://www.grid.ac/institutes/grid.5254.6
150 schema:familyName Gardner
151 schema:givenName Paul P
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224632205.56
153 rdf:type schema:Person
154 sg:person.0602700267.90 schema:affiliation https://www.grid.ac/institutes/grid.5254.6
155 schema:familyName Vinther
156 schema:givenName Jeppe
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602700267.90
158 rdf:type schema:Person
159 sg:pub.10.1038/nature03441 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050742226
160 https://doi.org/10.1038/nature03441
161 rdf:type schema:CreativeWork
162 sg:pub.10.1038/nature05113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037216489
163 https://doi.org/10.1038/nature05113
164 rdf:type schema:CreativeWork
165 sg:pub.10.1038/nbt1144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028917438
166 https://doi.org/10.1038/nbt1144
167 rdf:type schema:CreativeWork
168 sg:pub.10.1038/nrg1321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013684976
169 https://doi.org/10.1038/nrg1321
170 rdf:type schema:CreativeWork
171 sg:pub.10.1186/1471-2105-2-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046362248
172 https://doi.org/10.1186/1471-2105-2-8
173 rdf:type schema:CreativeWork
174 sg:pub.10.1186/1471-2105-6-241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005448112
175 https://doi.org/10.1186/1471-2105-6-241
176 rdf:type schema:CreativeWork
177 sg:pub.10.1186/1471-2105-7-239 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015800611
178 https://doi.org/10.1186/1471-2105-7-239
179 rdf:type schema:CreativeWork
180 sg:pub.10.1186/1471-2164-6-104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027055001
181 https://doi.org/10.1186/1471-2164-6-104
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.cell.2004.12.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017459887
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/s0022-2836(02)00308-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013627034
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1073/pnas.0409169102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016701541
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1073/pnas.0511155103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020588539
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1073/pnas.1932072100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024489496
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1093/nar/gkh103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040312195
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1093/nar/gki025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038073766
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1093/nar/gki541 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008319008
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1093/nar/gkj002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023486309
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1093/nar/gkj112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036093015
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1093/nar/gkj133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053168823
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1093/nar/gkj135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024707863
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1101/gr.1933104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028112195
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1101/gr.3455305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005251190
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1101/gr.3715005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048048079
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1101/gr.4200206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043481930
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1101/gr.4624306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043516206
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1101/gr.5159906 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050807485
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1101/gr.5650707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028375537
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1126/science.1098119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022514256
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1126/science.1108625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046921907
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1126/science.1112014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052847323
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1261/rna.2322506 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036696023
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1371/journal.pcbi.0020005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052454746
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1371/journal.pcbi.0020033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053214791
232 rdf:type schema:CreativeWork
233 https://www.grid.ac/institutes/grid.5254.6 schema:alternateName University of Copenhagen
234 schema:name Molecular Evolution Group, Department of Molecular Biology, University of Copenhagen, Ole Maaløes Vej 5, Building 4.1.27, DK-2200, Copenhagen N, Denmark
235 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...