The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Javier Prado-Martinez, Irene Hernando-Herraez, Belen Lorente-Galdos, Marc Dabad, Oscar Ramirez, Carlos Baeza-Delgado, Carlos Morcillo-Suarez, Can Alkan, Fereydoun Hormozdiari, Emanuele Raineri, Jordi Estellé, Marcos Fernandez-Callejo, Mònica Valles, Lars Ritscher, Torsten Schöneberg, Elisa de la Calle-Mustienes, Sònia Casillas, Raquel Rubio-Acero, Marta Melé, Johannes Engelken, Mario Caceres, Jose Luis Gomez-Skarmeta, Marta Gut, Jaume Bertranpetit, Ivo G Gut, Teresa Abello, Evan E Eichler, Ismael Mingarro, Carles Lalueza-Fox, Arcadi Navarro, Tomas Marques-Bonet

ABSTRACT

BACKGROUND: The only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albinism, i.e. white hair, light eyes, pink skin, photophobia and reduced visual acuity. Despite previous efforts to explain the genetic cause, this is still unknown. Here, we study the genetic cause of his albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other gorillas. RESULTS: We successfully identified the causal genetic variant for Snowflake's albinism, a non-synonymous single nucleotide variant located in a transmembrane region of SLC45A2. This transporter is known to be involved in oculocutaneous albinism type 4 (OCA4) in humans. We provide experimental evidence that shows that this amino acid replacement alters the membrane spanning capability of this transmembrane region. Finally, we provide a comprehensive study of genome-wide patterns of autozygogosity revealing that Snowflake's parents were related, being this the first report of inbreeding in a wild born Western lowland gorilla. CONCLUSIONS: In this study we demonstrate how the use of whole genome sequencing can be extended to link genotype and phenotype in non-model organisms and it can be a powerful tool in conservation genetics (e.g., inbreeding and genetic diversity) with the expected decrease in sequencing cost. More... »

PAGES

363

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1471-2164-14-363

DOI

http://dx.doi.org/10.1186/1471-2164-14-363

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019054875

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23721540


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genomics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gorilla gorilla", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heterozygote", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "High-Throughput Nucleotide Sequencing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Inbreeding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membrane Transport Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microsatellite Repeats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, DNA", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Prado-Martinez", 
        "givenName": "Javier", 
        "id": "sg:person.01057433203.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057433203.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hernando-Herraez", 
        "givenName": "Irene", 
        "id": "sg:person.0641630360.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641630360.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lorente-Galdos", 
        "givenName": "Belen", 
        "id": "sg:person.01050562365.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050562365.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dabad", 
        "givenName": "Marc", 
        "id": "sg:person.0756056760.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756056760.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ramirez", 
        "givenName": "Oscar", 
        "id": "sg:person.01264213127.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264213127.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Valencia", 
          "id": "https://www.grid.ac/institutes/grid.5338.d", 
          "name": [
            "Departament de Bioqu\u00edmica i Biologia Molecular, Universitat de Val\u00e8ncia, E-46100, Burjassot, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baeza-Delgado", 
        "givenName": "Carlos", 
        "id": "sg:person.01303530711.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01303530711.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain", 
            "Instituto Nacional de Bioinformatica, UPF, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morcillo-Suarez", 
        "givenName": "Carlos", 
        "id": "sg:person.01024100127.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01024100127.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bilkent University", 
          "id": "https://www.grid.ac/institutes/grid.18376.3b", 
          "name": [
            "Department of Genome Sciences, University of Washington, 3720 15th AVE NE, 98195, Seattle, WA, USA", 
            "Department of Computer Engineering, Bilkent University, Ankara, Turkey"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alkan", 
        "givenName": "Can", 
        "id": "sg:person.0737070412.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737070412.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Genome Sciences, University of Washington, 3720 15th AVE NE, 98195, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hormozdiari", 
        "givenName": "Fereydoun", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centro Nacional de An\u00e1lisis Gen\u00f3mico", 
          "id": "https://www.grid.ac/institutes/grid.452341.5", 
          "name": [
            "Centro Nacional de An\u00e1lisis Gen\u00f3mico, PCB, 08028, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raineri", 
        "givenName": "Emanuele", 
        "id": "sg:person.01034067302.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034067302.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centro Nacional de An\u00e1lisis Gen\u00f3mico", 
          "id": "https://www.grid.ac/institutes/grid.452341.5", 
          "name": [
            "Centro Nacional de An\u00e1lisis Gen\u00f3mico, PCB, 08028, Barcelona, Spain", 
            "INRA, UMR1313 GABI, Jouy-en-Josas, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Estell\u00e9", 
        "givenName": "Jordi", 
        "id": "sg:person.01313764065.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313764065.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fernandez-Callejo", 
        "givenName": "Marcos", 
        "id": "sg:person.0577661520.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577661520.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Valles", 
        "givenName": "M\u00f2nica", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leipzig University", 
          "id": "https://www.grid.ac/institutes/grid.9647.c", 
          "name": [
            "Institute of Biochemistry, University of Leipzig, 04103, Leipzig, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ritscher", 
        "givenName": "Lars", 
        "id": "sg:person.01317713441.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317713441.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leipzig University", 
          "id": "https://www.grid.ac/institutes/grid.9647.c", 
          "name": [
            "Institute of Biochemistry, University of Leipzig, 04103, Leipzig, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sch\u00f6neberg", 
        "givenName": "Torsten", 
        "id": "sg:person.01207326141.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207326141.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centro Andaluz de Biolog\u00eda del Desarrollo", 
          "id": "https://www.grid.ac/institutes/grid.428448.6", 
          "name": [
            "Centro Andaluz de Biolog\u00eda del Desarrollo, Consejo Superior de Investigaciones Cient\u00edficas, Universidad Pablo de Olavide and Junta de Andaluc\u00eda, Carretera de Utrera Km1, 41013, Sevilla, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de la Calle-Mustienes", 
        "givenName": "Elisa", 
        "id": "sg:person.0600237441.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600237441.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Autonomous University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.7080.f", 
          "name": [
            "Institut de Biotecnologia i de Biomedicina, Universitat Aut\u00f2noma de Barcelona, 08193, Bellaterra, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Casillas", 
        "givenName": "S\u00f2nia", 
        "id": "sg:person.01266647311.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266647311.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Autonomous University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.7080.f", 
          "name": [
            "Institut de Biotecnologia i de Biomedicina, Universitat Aut\u00f2noma de Barcelona, 08193, Bellaterra, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rubio-Acero", 
        "givenName": "Raquel", 
        "id": "sg:person.01052353103.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052353103.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Genomic Regulation", 
          "id": "https://www.grid.ac/institutes/grid.11478.3b", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain", 
            "Centre for Genomic Regulation and UPF, Doctor Aiguader 88, 08003, BarcelonaCatalonia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mel\u00e9", 
        "givenName": "Marta", 
        "id": "sg:person.011526330120.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011526330120.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Max Planck Institute for Evolutionary Anthropology", 
          "id": "https://www.grid.ac/institutes/grid.419518.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain", 
            "Department of Evolutionary Genetics, Max-Planck Institute for Evolutionary Anthropology, 04103, Leipzig, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Engelken", 
        "givenName": "Johannes", 
        "id": "sg:person.01060330575.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060330575.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats", 
          "id": "https://www.grid.ac/institutes/grid.425902.8", 
          "name": [
            "Institut de Biotecnologia i de Biomedicina, Universitat Aut\u00f2noma de Barcelona, 08193, Bellaterra, Barcelona, Spain", 
            "Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats (ICREA), 08010, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Caceres", 
        "givenName": "Mario", 
        "id": "sg:person.0743601622.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743601622.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centro Andaluz de Biolog\u00eda del Desarrollo", 
          "id": "https://www.grid.ac/institutes/grid.428448.6", 
          "name": [
            "Centro Andaluz de Biolog\u00eda del Desarrollo, Consejo Superior de Investigaciones Cient\u00edficas, Universidad Pablo de Olavide and Junta de Andaluc\u00eda, Carretera de Utrera Km1, 41013, Sevilla, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gomez-Skarmeta", 
        "givenName": "Jose Luis", 
        "id": "sg:person.01077027641.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077027641.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centro Nacional de An\u00e1lisis Gen\u00f3mico", 
          "id": "https://www.grid.ac/institutes/grid.452341.5", 
          "name": [
            "Centro Nacional de An\u00e1lisis Gen\u00f3mico, PCB, 08028, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gut", 
        "givenName": "Marta", 
        "id": "sg:person.0626544440.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626544440.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bertranpetit", 
        "givenName": "Jaume", 
        "id": "sg:person.0604654434.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604654434.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centro Nacional de An\u00e1lisis Gen\u00f3mico", 
          "id": "https://www.grid.ac/institutes/grid.452341.5", 
          "name": [
            "Centro Nacional de An\u00e1lisis Gen\u00f3mico, PCB, 08028, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gut", 
        "givenName": "Ivo G", 
        "id": "sg:person.0766073747.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766073747.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Parc Zool\u00f2gic de Barcelona, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abello", 
        "givenName": "Teresa", 
        "id": "sg:person.01034177620.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034177620.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Genome Sciences, University of Washington, 3720 15th AVE NE, 98195, Seattle, WA, USA", 
            "Howard Hugues Medical Institute, 3720 15th AVE NE, 98195, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eichler", 
        "givenName": "Evan E", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Valencia", 
          "id": "https://www.grid.ac/institutes/grid.5338.d", 
          "name": [
            "Departament de Bioqu\u00edmica i Biologia Molecular, Universitat de Val\u00e8ncia, E-46100, Burjassot, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mingarro", 
        "givenName": "Ismael", 
        "id": "sg:person.01264551640.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264551640.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lalueza-Fox", 
        "givenName": "Carles", 
        "id": "sg:person.01362101520.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362101520.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Genomic Regulation", 
          "id": "https://www.grid.ac/institutes/grid.11478.3b", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain", 
            "Instituto Nacional de Bioinformatica, UPF, Barcelona, Spain", 
            "Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats (ICREA), 08010, Barcelona, Spain", 
            "Centre for Genomic Regulation and UPF, Doctor Aiguader 88, 08003, BarcelonaCatalonia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Navarro", 
        "givenName": "Arcadi", 
        "id": "sg:person.01022735361.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022735361.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats", 
          "id": "https://www.grid.ac/institutes/grid.425902.8", 
          "name": [
            "Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain", 
            "Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats (ICREA), 08010, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marques-Bonet", 
        "givenName": "Tomas", 
        "id": "sg:person.0775754503.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775754503.55"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/molbev/msl160", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001804028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajp.20069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001952236"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng584", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002187015", 
          "https://doi.org/10.1038/ng584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng584", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002187015", 
          "https://doi.org/10.1038/ng584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkg509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002198958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.106.063107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003931395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.106.063107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003931395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2004.02.062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005114045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1297-9686-35-1-119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005868817", 
          "https://doi.org/10.1186/1297-9686-35-1-119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth0410-248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007489634", 
          "https://doi.org/10.1038/nmeth0410-248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth0410-248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007489634", 
          "https://doi.org/10.1038/nmeth0410-248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.virol.2007.06.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007773555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0749.2006.00332.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008478990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajp.20070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009453451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10592-009-0015-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012890008", 
          "https://doi.org/10.1007/s10592-009-0015-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10592-009-0015-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012890008", 
          "https://doi.org/10.1007/s10592-009-0015-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10592-009-0015-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012890008", 
          "https://doi.org/10.1007/s10592-009-0015-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1034/j.1600-0749.2000.130609.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015255782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1750-1172-2-43", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015657888", 
          "https://doi.org/10.1186/1750-1172-2-43"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10842", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019463387", 
          "https://doi.org/10.1038/nature10842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020406938", 
          "https://doi.org/10.1038/nature09807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-294x.2006.03159.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021303189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btp352", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023014918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/324340", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024330379"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.2221", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025012822", 
          "https://doi.org/10.1038/nmeth.2221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg2664", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026268014", 
          "https://doi.org/10.1038/nrg2664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg2664", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026268014", 
          "https://doi.org/10.1038/nrg2664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1000648", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029774673"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1529/biophysj.108.138602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030632831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11236", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031877813", 
          "https://doi.org/10.1038/nature11236"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajp.20445", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032117098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2010-11-12-r119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033784968", 
          "https://doi.org/10.1186/gb-2010-11-12-r119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/263226a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035370992", 
          "https://doi.org/10.1038/263226a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajhg.2012.06.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040845373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-294x.2007.03286.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042352156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000155115", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042362614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.124461.111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048823595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00265-003-0630-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048836522", 
          "https://doi.org/10.1007/s00265-003-0630-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050556652", 
          "https://doi.org/10.1038/nature03216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050556652", 
          "https://doi.org/10.1038/nature03216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1354/vp.45-4-531", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051531774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1354/vp.45-4-531", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051531774"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-12", 
    "datePublishedReg": "2013-12-01", 
    "description": "BACKGROUND: The only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albinism, i.e. white hair, light eyes, pink skin, photophobia and reduced visual acuity. Despite previous efforts to explain the genetic cause, this is still unknown. Here, we study the genetic cause of his albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other gorillas.\nRESULTS: We successfully identified the causal genetic variant for Snowflake's albinism, a non-synonymous single nucleotide variant located in a transmembrane region of SLC45A2. This transporter is known to be involved in oculocutaneous albinism type 4 (OCA4) in humans. We provide experimental evidence that shows that this amino acid replacement alters the membrane spanning capability of this transmembrane region. Finally, we provide a comprehensive study of genome-wide patterns of autozygogosity revealing that Snowflake's parents were related, being this the first report of inbreeding in a wild born Western lowland gorilla.\nCONCLUSIONS: In this study we demonstrate how the use of whole genome sequencing can be extended to link genotype and phenotype in non-model organisms and it can be a powerful tool in conservation genetics (e.g., inbreeding and genetic diversity) with the expected decrease in sequencing cost.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/1471-2164-14-363", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3789993", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3772378", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1023790", 
        "issn": [
          "1471-2164"
        ], 
        "name": "BMC Genomics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "14"
      }
    ], 
    "name": "The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild", 
    "pagination": "363", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5aca381365ee8b8acd765502b77e47acc09a218775006d4a616a9d84eae9e422"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23721540"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100965258"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/1471-2164-14-363"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019054875"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/1471-2164-14-363", 
      "https://app.dimensions.ai/details/publication/pub.1019054875"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000504.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2F1471-2164-14-363"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-14-363'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-14-363'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-14-363'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/1471-2164-14-363'


 

This table displays all metadata directly associated to this object as RDF triples.

493 TRIPLES      21 PREDICATES      77 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/1471-2164-14-363 schema:about N109373d239974dc08dc3b69c634f1342
2 N5333af50dcf1499ca8687f38a96ff6ae
3 N6c1977785cff427087d3e62ab6df7e60
4 N8069d8392c584d0e9c012ff5a902889f
5 N8f43bd378c7e4129bb72ba840ef0f6ee
6 N9388c4c0a57b42c7bf7d9717efa80b22
7 N93b99b9cda4a465b9d8e156abe986013
8 N9d27954f6df2432a8dac0a5976884ea7
9 Na41e734a383a48b9b89adbe063d17771
10 Nb27d0acb7fb44ecdb8fe8140609dd72f
11 Nbf61b99862574fbabe6e8e742859ba77
12 Nc60f3501257e4eab80c800030059bf93
13 Nd57f8d4e8bdc465aa7971844363059ba
14 Ne2c461c49ce042e0b30bc431083ce726
15 anzsrc-for:06
16 anzsrc-for:0604
17 schema:author N4312b5a186434e9e8afd1529d1168333
18 schema:citation sg:pub.10.1007/s00265-003-0630-3
19 sg:pub.10.1007/s10592-009-0015-x
20 sg:pub.10.1038/263226a0
21 sg:pub.10.1038/nature03216
22 sg:pub.10.1038/nature09807
23 sg:pub.10.1038/nature10842
24 sg:pub.10.1038/nature11236
25 sg:pub.10.1038/ng584
26 sg:pub.10.1038/nmeth.2221
27 sg:pub.10.1038/nmeth0410-248
28 sg:pub.10.1038/nrg2664
29 sg:pub.10.1186/1297-9686-35-1-119
30 sg:pub.10.1186/1750-1172-2-43
31 sg:pub.10.1186/gb-2010-11-12-r119
32 https://doi.org/10.1002/ajp.20069
33 https://doi.org/10.1002/ajp.20070
34 https://doi.org/10.1002/ajp.20445
35 https://doi.org/10.1016/j.ajhg.2012.06.014
36 https://doi.org/10.1016/j.cub.2004.02.062
37 https://doi.org/10.1016/j.virol.2007.06.006
38 https://doi.org/10.1034/j.1600-0749.2000.130609.x
39 https://doi.org/10.1086/324340
40 https://doi.org/10.1093/bioinformatics/btp352
41 https://doi.org/10.1093/molbev/msl160
42 https://doi.org/10.1093/nar/gkg509
43 https://doi.org/10.1101/gr.124461.111
44 https://doi.org/10.1111/j.1365-294x.2006.03159.x
45 https://doi.org/10.1111/j.1365-294x.2007.03286.x
46 https://doi.org/10.1111/j.1600-0749.2006.00332.x
47 https://doi.org/10.1159/000155115
48 https://doi.org/10.1354/vp.45-4-531
49 https://doi.org/10.1371/journal.pgen.1000648
50 https://doi.org/10.1529/biophysj.108.138602
51 https://doi.org/10.1534/genetics.106.063107
52 schema:datePublished 2013-12
53 schema:datePublishedReg 2013-12-01
54 schema:description BACKGROUND: The only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous albinism, i.e. white hair, light eyes, pink skin, photophobia and reduced visual acuity. Despite previous efforts to explain the genetic cause, this is still unknown. Here, we study the genetic cause of his albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other gorillas. RESULTS: We successfully identified the causal genetic variant for Snowflake's albinism, a non-synonymous single nucleotide variant located in a transmembrane region of SLC45A2. This transporter is known to be involved in oculocutaneous albinism type 4 (OCA4) in humans. We provide experimental evidence that shows that this amino acid replacement alters the membrane spanning capability of this transmembrane region. Finally, we provide a comprehensive study of genome-wide patterns of autozygogosity revealing that Snowflake's parents were related, being this the first report of inbreeding in a wild born Western lowland gorilla. CONCLUSIONS: In this study we demonstrate how the use of whole genome sequencing can be extended to link genotype and phenotype in non-model organisms and it can be a powerful tool in conservation genetics (e.g., inbreeding and genetic diversity) with the expected decrease in sequencing cost.
55 schema:genre research_article
56 schema:inLanguage en
57 schema:isAccessibleForFree true
58 schema:isPartOf N0c3dd5b57ef54d7c8a5cf8883201bbd7
59 Nab4debb1a1224469a06696cc46457ca5
60 sg:journal.1023790
61 schema:name The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild
62 schema:pagination 363
63 schema:productId N0aaadb2115ff4b8e8513c65a7220bd36
64 N35c4374ebc6f4c65aa70e319b55fe41f
65 N38de7c20a26749ee912143b8b03dc545
66 N5050719d76e74c1e86f99376b4063c78
67 Nef2241a13ae842a3bd99ed2edfde0011
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019054875
69 https://doi.org/10.1186/1471-2164-14-363
70 schema:sdDatePublished 2019-04-10T17:29
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher N3cede837579b437bab98751814969ca2
73 schema:url http://link.springer.com/10.1186%2F1471-2164-14-363
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N071036f381dd4896a89753dca53f321b schema:name Parc Zoològic de Barcelona, 08003, Barcelona, Spain
78 rdf:type schema:Organization
79 N0aaadb2115ff4b8e8513c65a7220bd36 schema:name dimensions_id
80 schema:value pub.1019054875
81 rdf:type schema:PropertyValue
82 N0aca3917625047ee8a107fd09053e215 rdf:first sg:person.01303530711.46
83 rdf:rest N61fa1c33c5914c898d2d80b5156c4972
84 N0c3dd5b57ef54d7c8a5cf8883201bbd7 schema:volumeNumber 14
85 rdf:type schema:PublicationVolume
86 N109373d239974dc08dc3b69c634f1342 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Gorilla gorilla
88 rdf:type schema:DefinedTerm
89 N10d39fc29fc14f27bab42446f1779735 rdf:first sg:person.01034067302.26
90 rdf:rest N8b5e07d9c0f548abae7d40a995e40d17
91 N142b777bce0749bba9d7cdc12ff625e8 rdf:first sg:person.01264551640.54
92 rdf:rest N68573701fb91429ba019a39dd6ff3b4c
93 N15728a274b31449d9af2638cf0a43766 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
94 schema:familyName Hormozdiari
95 schema:givenName Fereydoun
96 rdf:type schema:Person
97 N1ce3b418bfc84d6fb8f69993b06f060c rdf:first sg:person.0641630360.62
98 rdf:rest N261132f5948a4e2d8984c47c8393af58
99 N2007b2f0ea9b4bc2923a8e1c7338e5f3 rdf:first sg:person.0737070412.26
100 rdf:rest N8a22157ceb4d48d5926586824d56a581
101 N2204d0afba7b4c9b9201563598c6f192 rdf:first N97aee710d8a448b793feb6c799ece26a
102 rdf:rest N142b777bce0749bba9d7cdc12ff625e8
103 N261132f5948a4e2d8984c47c8393af58 rdf:first sg:person.01050562365.46
104 rdf:rest N34be767d525e4fa0a647c10d2889195a
105 N29f4789a90fd4f9f97cfc7affb0e5a3c rdf:first sg:person.0766073747.27
106 rdf:rest N2deaec9a1dd2412781e5cec7bd6a1b71
107 N2deaec9a1dd2412781e5cec7bd6a1b71 rdf:first sg:person.01034177620.79
108 rdf:rest N2204d0afba7b4c9b9201563598c6f192
109 N34be767d525e4fa0a647c10d2889195a rdf:first sg:person.0756056760.58
110 rdf:rest N954a222f21254bbd93504bd2b3616339
111 N35c4374ebc6f4c65aa70e319b55fe41f schema:name nlm_unique_id
112 schema:value 100965258
113 rdf:type schema:PropertyValue
114 N38de7c20a26749ee912143b8b03dc545 schema:name readcube_id
115 schema:value 5aca381365ee8b8acd765502b77e47acc09a218775006d4a616a9d84eae9e422
116 rdf:type schema:PropertyValue
117 N3cede837579b437bab98751814969ca2 schema:name Springer Nature - SN SciGraph project
118 rdf:type schema:Organization
119 N409c618816a948afaca51cc88f465a80 rdf:first sg:person.01022735361.32
120 rdf:rest Ne84cb4b239ef4653ad6ce927777e38aa
121 N4312b5a186434e9e8afd1529d1168333 rdf:first sg:person.01057433203.72
122 rdf:rest N1ce3b418bfc84d6fb8f69993b06f060c
123 N5050719d76e74c1e86f99376b4063c78 schema:name doi
124 schema:value 10.1186/1471-2164-14-363
125 rdf:type schema:PropertyValue
126 N5333af50dcf1499ca8687f38a96ff6ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Sequence Analysis, DNA
128 rdf:type schema:DefinedTerm
129 N54465e451c004ce7a488c384e6eadf91 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
130 schema:familyName Valles
131 schema:givenName Mònica
132 rdf:type schema:Person
133 N5e65e03d4fd149a2adabf00935212d0e rdf:first sg:person.0626544440.66
134 rdf:rest Nb58819ce005844ad9c77746143e3bdc0
135 N61fa1c33c5914c898d2d80b5156c4972 rdf:first sg:person.01024100127.12
136 rdf:rest N2007b2f0ea9b4bc2923a8e1c7338e5f3
137 N68573701fb91429ba019a39dd6ff3b4c rdf:first sg:person.01362101520.29
138 rdf:rest N409c618816a948afaca51cc88f465a80
139 N6ba203f42e9c4a69a46e961eeec01770 rdf:first sg:person.011526330120.45
140 rdf:rest Nec6b329372e34f93b81abfa97a98968e
141 N6c1977785cff427087d3e62ab6df7e60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Amino Acid Sequence
143 rdf:type schema:DefinedTerm
144 N8069d8392c584d0e9c012ff5a902889f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Female
146 rdf:type schema:DefinedTerm
147 N8a22157ceb4d48d5926586824d56a581 rdf:first N15728a274b31449d9af2638cf0a43766
148 rdf:rest N10d39fc29fc14f27bab42446f1779735
149 N8b5e07d9c0f548abae7d40a995e40d17 rdf:first sg:person.01313764065.32
150 rdf:rest Nf073677951f74cf69a9180770781ef47
151 N8f43bd378c7e4129bb72ba840ef0f6ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Molecular Sequence Data
153 rdf:type schema:DefinedTerm
154 N9388c4c0a57b42c7bf7d9717efa80b22 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name High-Throughput Nucleotide Sequencing
156 rdf:type schema:DefinedTerm
157 N93b99b9cda4a465b9d8e156abe986013 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Microsatellite Repeats
159 rdf:type schema:DefinedTerm
160 N954a222f21254bbd93504bd2b3616339 rdf:first sg:person.01264213127.03
161 rdf:rest N0aca3917625047ee8a107fd09053e215
162 N95521003f7ea48e2803a7ae2e6b7eeb3 rdf:first sg:person.01052353103.65
163 rdf:rest N6ba203f42e9c4a69a46e961eeec01770
164 N97aee710d8a448b793feb6c799ece26a schema:affiliation https://www.grid.ac/institutes/grid.34477.33
165 schema:familyName Eichler
166 schema:givenName Evan E
167 rdf:type schema:Person
168 N9d27954f6df2432a8dac0a5976884ea7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Inbreeding
170 rdf:type schema:DefinedTerm
171 Na41e734a383a48b9b89adbe063d17771 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Male
173 rdf:type schema:DefinedTerm
174 Nab4debb1a1224469a06696cc46457ca5 schema:issueNumber 1
175 rdf:type schema:PublicationIssue
176 Nb27d0acb7fb44ecdb8fe8140609dd72f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Genomics
178 rdf:type schema:DefinedTerm
179 Nb58819ce005844ad9c77746143e3bdc0 rdf:first sg:person.0604654434.69
180 rdf:rest N29f4789a90fd4f9f97cfc7affb0e5a3c
181 Nbc40620f407d4d7c95353b3d0f153e47 rdf:first N54465e451c004ce7a488c384e6eadf91
182 rdf:rest Ncd3359986a814afcb03f2a9ad9a1bc24
183 Nbcd3d0fdd0274e5b8c21d6842e01fa59 rdf:first sg:person.01077027641.36
184 rdf:rest N5e65e03d4fd149a2adabf00935212d0e
185 Nbf4d1f3f3dba48eab44b232092b5fc4a rdf:first sg:person.0743601622.51
186 rdf:rest Nbcd3d0fdd0274e5b8c21d6842e01fa59
187 Nbf61b99862574fbabe6e8e742859ba77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Heterozygote
189 rdf:type schema:DefinedTerm
190 Nc60f3501257e4eab80c800030059bf93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Mutation
192 rdf:type schema:DefinedTerm
193 Nc7ab39f4ebb64cf38d1cb4e5073fb0db rdf:first sg:person.0600237441.55
194 rdf:rest Nd55d02f02ed84bf09ff663abec790a2b
195 Ncd3359986a814afcb03f2a9ad9a1bc24 rdf:first sg:person.01317713441.22
196 rdf:rest Ndba35b87ac6647869f9259f8099b213b
197 Nd55d02f02ed84bf09ff663abec790a2b rdf:first sg:person.01266647311.74
198 rdf:rest N95521003f7ea48e2803a7ae2e6b7eeb3
199 Nd57f8d4e8bdc465aa7971844363059ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Membrane Transport Proteins
201 rdf:type schema:DefinedTerm
202 Ndba35b87ac6647869f9259f8099b213b rdf:first sg:person.01207326141.69
203 rdf:rest Nc7ab39f4ebb64cf38d1cb4e5073fb0db
204 Ne2c461c49ce042e0b30bc431083ce726 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Animals
206 rdf:type schema:DefinedTerm
207 Ne84cb4b239ef4653ad6ce927777e38aa rdf:first sg:person.0775754503.55
208 rdf:rest rdf:nil
209 Nec6b329372e34f93b81abfa97a98968e rdf:first sg:person.01060330575.48
210 rdf:rest Nbf4d1f3f3dba48eab44b232092b5fc4a
211 Nef2241a13ae842a3bd99ed2edfde0011 schema:name pubmed_id
212 schema:value 23721540
213 rdf:type schema:PropertyValue
214 Nf073677951f74cf69a9180770781ef47 rdf:first sg:person.0577661520.61
215 rdf:rest Nbc40620f407d4d7c95353b3d0f153e47
216 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
217 schema:name Biological Sciences
218 rdf:type schema:DefinedTerm
219 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
220 schema:name Genetics
221 rdf:type schema:DefinedTerm
222 sg:grant.3772378 http://pending.schema.org/fundedItem sg:pub.10.1186/1471-2164-14-363
223 rdf:type schema:MonetaryGrant
224 sg:grant.3789993 http://pending.schema.org/fundedItem sg:pub.10.1186/1471-2164-14-363
225 rdf:type schema:MonetaryGrant
226 sg:journal.1023790 schema:issn 1471-2164
227 schema:name BMC Genomics
228 rdf:type schema:Periodical
229 sg:person.01022735361.32 schema:affiliation https://www.grid.ac/institutes/grid.11478.3b
230 schema:familyName Navarro
231 schema:givenName Arcadi
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022735361.32
233 rdf:type schema:Person
234 sg:person.01024100127.12 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
235 schema:familyName Morcillo-Suarez
236 schema:givenName Carlos
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01024100127.12
238 rdf:type schema:Person
239 sg:person.01034067302.26 schema:affiliation https://www.grid.ac/institutes/grid.452341.5
240 schema:familyName Raineri
241 schema:givenName Emanuele
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034067302.26
243 rdf:type schema:Person
244 sg:person.01034177620.79 schema:affiliation N071036f381dd4896a89753dca53f321b
245 schema:familyName Abello
246 schema:givenName Teresa
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034177620.79
248 rdf:type schema:Person
249 sg:person.01050562365.46 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
250 schema:familyName Lorente-Galdos
251 schema:givenName Belen
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050562365.46
253 rdf:type schema:Person
254 sg:person.01052353103.65 schema:affiliation https://www.grid.ac/institutes/grid.7080.f
255 schema:familyName Rubio-Acero
256 schema:givenName Raquel
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052353103.65
258 rdf:type schema:Person
259 sg:person.01057433203.72 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
260 schema:familyName Prado-Martinez
261 schema:givenName Javier
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057433203.72
263 rdf:type schema:Person
264 sg:person.01060330575.48 schema:affiliation https://www.grid.ac/institutes/grid.419518.0
265 schema:familyName Engelken
266 schema:givenName Johannes
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060330575.48
268 rdf:type schema:Person
269 sg:person.01077027641.36 schema:affiliation https://www.grid.ac/institutes/grid.428448.6
270 schema:familyName Gomez-Skarmeta
271 schema:givenName Jose Luis
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077027641.36
273 rdf:type schema:Person
274 sg:person.011526330120.45 schema:affiliation https://www.grid.ac/institutes/grid.11478.3b
275 schema:familyName Melé
276 schema:givenName Marta
277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011526330120.45
278 rdf:type schema:Person
279 sg:person.01207326141.69 schema:affiliation https://www.grid.ac/institutes/grid.9647.c
280 schema:familyName Schöneberg
281 schema:givenName Torsten
282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207326141.69
283 rdf:type schema:Person
284 sg:person.01264213127.03 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
285 schema:familyName Ramirez
286 schema:givenName Oscar
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264213127.03
288 rdf:type schema:Person
289 sg:person.01264551640.54 schema:affiliation https://www.grid.ac/institutes/grid.5338.d
290 schema:familyName Mingarro
291 schema:givenName Ismael
292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264551640.54
293 rdf:type schema:Person
294 sg:person.01266647311.74 schema:affiliation https://www.grid.ac/institutes/grid.7080.f
295 schema:familyName Casillas
296 schema:givenName Sònia
297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266647311.74
298 rdf:type schema:Person
299 sg:person.01303530711.46 schema:affiliation https://www.grid.ac/institutes/grid.5338.d
300 schema:familyName Baeza-Delgado
301 schema:givenName Carlos
302 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01303530711.46
303 rdf:type schema:Person
304 sg:person.01313764065.32 schema:affiliation https://www.grid.ac/institutes/grid.452341.5
305 schema:familyName Estellé
306 schema:givenName Jordi
307 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313764065.32
308 rdf:type schema:Person
309 sg:person.01317713441.22 schema:affiliation https://www.grid.ac/institutes/grid.9647.c
310 schema:familyName Ritscher
311 schema:givenName Lars
312 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317713441.22
313 rdf:type schema:Person
314 sg:person.01362101520.29 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
315 schema:familyName Lalueza-Fox
316 schema:givenName Carles
317 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362101520.29
318 rdf:type schema:Person
319 sg:person.0577661520.61 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
320 schema:familyName Fernandez-Callejo
321 schema:givenName Marcos
322 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577661520.61
323 rdf:type schema:Person
324 sg:person.0600237441.55 schema:affiliation https://www.grid.ac/institutes/grid.428448.6
325 schema:familyName de la Calle-Mustienes
326 schema:givenName Elisa
327 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600237441.55
328 rdf:type schema:Person
329 sg:person.0604654434.69 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
330 schema:familyName Bertranpetit
331 schema:givenName Jaume
332 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604654434.69
333 rdf:type schema:Person
334 sg:person.0626544440.66 schema:affiliation https://www.grid.ac/institutes/grid.452341.5
335 schema:familyName Gut
336 schema:givenName Marta
337 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626544440.66
338 rdf:type schema:Person
339 sg:person.0641630360.62 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
340 schema:familyName Hernando-Herraez
341 schema:givenName Irene
342 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641630360.62
343 rdf:type schema:Person
344 sg:person.0737070412.26 schema:affiliation https://www.grid.ac/institutes/grid.18376.3b
345 schema:familyName Alkan
346 schema:givenName Can
347 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737070412.26
348 rdf:type schema:Person
349 sg:person.0743601622.51 schema:affiliation https://www.grid.ac/institutes/grid.425902.8
350 schema:familyName Caceres
351 schema:givenName Mario
352 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743601622.51
353 rdf:type schema:Person
354 sg:person.0756056760.58 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
355 schema:familyName Dabad
356 schema:givenName Marc
357 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756056760.58
358 rdf:type schema:Person
359 sg:person.0766073747.27 schema:affiliation https://www.grid.ac/institutes/grid.452341.5
360 schema:familyName Gut
361 schema:givenName Ivo G
362 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766073747.27
363 rdf:type schema:Person
364 sg:person.0775754503.55 schema:affiliation https://www.grid.ac/institutes/grid.425902.8
365 schema:familyName Marques-Bonet
366 schema:givenName Tomas
367 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775754503.55
368 rdf:type schema:Person
369 sg:pub.10.1007/s00265-003-0630-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048836522
370 https://doi.org/10.1007/s00265-003-0630-3
371 rdf:type schema:CreativeWork
372 sg:pub.10.1007/s10592-009-0015-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1012890008
373 https://doi.org/10.1007/s10592-009-0015-x
374 rdf:type schema:CreativeWork
375 sg:pub.10.1038/263226a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035370992
376 https://doi.org/10.1038/263226a0
377 rdf:type schema:CreativeWork
378 sg:pub.10.1038/nature03216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050556652
379 https://doi.org/10.1038/nature03216
380 rdf:type schema:CreativeWork
381 sg:pub.10.1038/nature09807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020406938
382 https://doi.org/10.1038/nature09807
383 rdf:type schema:CreativeWork
384 sg:pub.10.1038/nature10842 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019463387
385 https://doi.org/10.1038/nature10842
386 rdf:type schema:CreativeWork
387 sg:pub.10.1038/nature11236 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031877813
388 https://doi.org/10.1038/nature11236
389 rdf:type schema:CreativeWork
390 sg:pub.10.1038/ng584 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002187015
391 https://doi.org/10.1038/ng584
392 rdf:type schema:CreativeWork
393 sg:pub.10.1038/nmeth.2221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025012822
394 https://doi.org/10.1038/nmeth.2221
395 rdf:type schema:CreativeWork
396 sg:pub.10.1038/nmeth0410-248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007489634
397 https://doi.org/10.1038/nmeth0410-248
398 rdf:type schema:CreativeWork
399 sg:pub.10.1038/nrg2664 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026268014
400 https://doi.org/10.1038/nrg2664
401 rdf:type schema:CreativeWork
402 sg:pub.10.1186/1297-9686-35-1-119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005868817
403 https://doi.org/10.1186/1297-9686-35-1-119
404 rdf:type schema:CreativeWork
405 sg:pub.10.1186/1750-1172-2-43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015657888
406 https://doi.org/10.1186/1750-1172-2-43
407 rdf:type schema:CreativeWork
408 sg:pub.10.1186/gb-2010-11-12-r119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033784968
409 https://doi.org/10.1186/gb-2010-11-12-r119
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1002/ajp.20069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001952236
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1002/ajp.20070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009453451
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1002/ajp.20445 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032117098
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1016/j.ajhg.2012.06.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040845373
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1016/j.cub.2004.02.062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005114045
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1016/j.virol.2007.06.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007773555
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1034/j.1600-0749.2000.130609.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015255782
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1086/324340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024330379
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1093/bioinformatics/btp352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023014918
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1093/molbev/msl160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001804028
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1093/nar/gkg509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002198958
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1101/gr.124461.111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048823595
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1111/j.1365-294x.2006.03159.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021303189
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1111/j.1365-294x.2007.03286.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042352156
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1111/j.1600-0749.2006.00332.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008478990
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1159/000155115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042362614
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1354/vp.45-4-531 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051531774
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1371/journal.pgen.1000648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029774673
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1529/biophysj.108.138602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030632831
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1534/genetics.106.063107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003931395
450 rdf:type schema:CreativeWork
451 https://www.grid.ac/institutes/grid.11478.3b schema:alternateName Centre for Genomic Regulation
452 schema:name Centre for Genomic Regulation and UPF, Doctor Aiguader 88, 08003, BarcelonaCatalonia, Spain
453 Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010, Barcelona, Spain
454 Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain
455 Instituto Nacional de Bioinformatica, UPF, Barcelona, Spain
456 rdf:type schema:Organization
457 https://www.grid.ac/institutes/grid.18376.3b schema:alternateName Bilkent University
458 schema:name Department of Computer Engineering, Bilkent University, Ankara, Turkey
459 Department of Genome Sciences, University of Washington, 3720 15th AVE NE, 98195, Seattle, WA, USA
460 rdf:type schema:Organization
461 https://www.grid.ac/institutes/grid.34477.33 schema:alternateName University of Washington
462 schema:name Department of Genome Sciences, University of Washington, 3720 15th AVE NE, 98195, Seattle, WA, USA
463 Howard Hugues Medical Institute, 3720 15th AVE NE, 98195, Seattle, WA, USA
464 rdf:type schema:Organization
465 https://www.grid.ac/institutes/grid.419518.0 schema:alternateName Max Planck Institute for Evolutionary Anthropology
466 schema:name Department of Evolutionary Genetics, Max-Planck Institute for Evolutionary Anthropology, 04103, Leipzig, Germany
467 Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain
468 rdf:type schema:Organization
469 https://www.grid.ac/institutes/grid.425902.8 schema:alternateName Institució Catalana de Recerca i Estudis Avançats
470 schema:name Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010, Barcelona, Spain
471 Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain
472 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain
473 rdf:type schema:Organization
474 https://www.grid.ac/institutes/grid.428448.6 schema:alternateName Centro Andaluz de Biología del Desarrollo
475 schema:name Centro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas, Universidad Pablo de Olavide and Junta de Andalucía, Carretera de Utrera Km1, 41013, Sevilla, Spain
476 rdf:type schema:Organization
477 https://www.grid.ac/institutes/grid.452341.5 schema:alternateName Centro Nacional de Análisis Genómico
478 schema:name Centro Nacional de Análisis Genómico, PCB, 08028, Barcelona, Spain
479 INRA, UMR1313 GABI, Jouy-en-Josas, France
480 rdf:type schema:Organization
481 https://www.grid.ac/institutes/grid.5338.d schema:alternateName University of Valencia
482 schema:name Departament de Bioquímica i Biologia Molecular, Universitat de València, E-46100, Burjassot, Spain
483 rdf:type schema:Organization
484 https://www.grid.ac/institutes/grid.5612.0 schema:alternateName Pompeu Fabra University
485 schema:name Institut de Biologia Evolutiva, (CSIC-Universitat Pompeu Fabra), PRBB, 08003, Barcelona, Spain
486 Instituto Nacional de Bioinformatica, UPF, Barcelona, Spain
487 rdf:type schema:Organization
488 https://www.grid.ac/institutes/grid.7080.f schema:alternateName Autonomous University of Barcelona
489 schema:name Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain
490 rdf:type schema:Organization
491 https://www.grid.ac/institutes/grid.9647.c schema:alternateName Leipzig University
492 schema:name Institute of Biochemistry, University of Leipzig, 04103, Leipzig, Germany
493 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...