Association studies for asthma and atopic diseases: a comprehensive review of the literature View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2003-12

AUTHORS

Sabine Hoffjan, Dan Nicolae, Carole Ober

ABSTRACT

Hundreds of genetic association studies on asthma-related phenotypes have been conducted in different populations. To date, variants in 64 genes have been reported to be associated with asthma or related traits in at least one study. Of these, 33 associations were replicated in a second study, 9 associations were not replicated either in a second study or a second sample in the same study, and 22 associations were reported in just a single published study. These results suggest the potential for a great amount of heterogeneity underlying asthma. However, many of these studies are methodologically limited and their interpretation hampered by small sample sizes. More... »

PAGES

14

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/1465-9921-4-14

    DOI

    http://dx.doi.org/10.1186/1465-9921-4-14

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1043096595

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14748924


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