Analysis of comorbid factors that increase the COPD assessment test scores View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Masaki Miyazaki, Hidetoshi Nakamura, Shotaro Chubachi, Mamoru Sasaki, Mizuha Haraguchi, Shuichi Yoshida, Keishi Tsuduki, Toru Shirahata, Saeko Takahashi, Naoto Minematsu, Hidefumi Koh, Morio Nakamura, Fumio Sakamaki, Takeshi Terashima, Koichi Sayama, Paul W Jones, Koichiro Asano, Tomoko Betsuyaku, The Keio COPD Comorbidity Research (K-CCR) Group

ABSTRACT

BACKGROUND: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. METHODS: An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients' reports, physicians' records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. RESULTS: The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. CONCLUSIONS: Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. TRIAL REGISTRATION: Clinical trial registered with UMIN (UMIN000003470). More... »

PAGES

13

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/1465-9921-15-13

DOI

http://dx.doi.org/10.1186/1465-9921-15-13

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037980314

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24502760


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