Possibility to interfere with malaria parasite activity using specific electromagnetic frequencies View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Irena Cosic, JoseLuis Hernandes Caceres, Drasko Cosic

ABSTRACT

The absence of clear breakthrough in malaria combat could support the need for different ways of tackling the disease that are substantiated by conceptually new bases. The main idea of this research is to analyze possibility to interfere with malaria parasite activity using specific resonant electromagnetic frequencies. Although the idea to combat malaria infection with electromagnetic frequencies is not new, we will here present unique approach, so called Resonant Recognition Model (RRM) to specifically identify electromagnetic frequencies mostly important for interference with malaria infection. The RRM is calculating periodicities (frequencies) in distribution of free electron energies along protein sequence which are relevant for protein function/interaction. When charge transfer through protein backbone is considered then it can produce electromagnetic radiation of specific frequency depending on charge velocity. Ten groups of proteins relevant for Plasmodium interactions were analyzed. Each of ten groups of proteins have at least one significant characteristic frequency peak at one of the following RRM frequencies: f = 0.002, f = 0.11 or f = 0.34. This suggests that the diversity of proteins participating in Plasmodium invasion could be represented with only three RRM frequencies. Depending on the charge transfer mechanism (velocity) along the protein, different electromagnetic resonant frequencies are expected. Based on presented results, we suggest that the RRM frequency of f = 0.002 (related to 2-5THz), to be regarded as crucial for Plasmodium infectivity and possibly for interfering with invasion process. Although this far infrared electromagnetic frequency cannot penetrate human body more than down to 4 cm, such radiation can be of great help in combating Plasmodium, since a sizeable part of parasite remain in the skin for hours after the mosquito bite. In addition the specific RRM frequency is capable to resonantly initiate a whole cascade of protein-protein (DNA, RNA) interactions directed to the specific biological activity which could contra-act Plasmodium infection. More... »

PAGES

11

Identifiers

URI

http://scigraph.springernature.com/pub.10.1140/epjnbp/s40366-015-0025-1

DOI

http://dx.doi.org/10.1140/epjnbp/s40366-015-0025-1

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https://app.dimensions.ai/details/publication/pub.1033248022


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