Concomitant action of organic and inorganic nanoparticles in wound healing and antibacterial resistance: Chitosan and copper nanoparticles in an ointment ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-01

AUTHORS

A. A. Rakhmetova, O. A. Bogoslovskaya, I. P. Olkhovskaya, A. N. Zhigach, A. V. Ilyina, V. P. Varlamov, N. N. Gluschenko

ABSTRACT

The wound-healing properties of organic and inorganic nanoparticles, i.e., chitosan and copper nanoparticles, cointroduced into an ointment preparation, were investigated. When used individually in the ointment, copper oxide nanoparticles at a concentration of 0.002% and a level of oxidation of up to 90% and nanoparticles of chitosan at a concentration of 0.002% prepared from chitosan with a molecular weight of 10 kDa demonstrated the most profound wound-healing effect. The simultaneous introduction of chitosan and copper nanoparticles into the ointment composition led to a synergistic effect. The most pronounced wound healing was observed for complex ointment preparations containing Cu1Ox sample 2 copper nanoparticles at a concentration of 0.002% and chitosan nanoparticles synthesized from low-molecularweight chitosan (Mw 10 kDa) with a degree of deacetylation (DD) of 89% at a concentration of 0.002%. An additive effect was observed for the complex ointment in comparison with ointment preparations based on individual components. Similar antibacterial effects were observed in ointment preparations based on organic and inorganic nanoparticles. More... »

PAGES

149-157

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s1995078015010164

DOI

http://dx.doi.org/10.1134/s1995078015010164

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044204765


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.434999.a", 
          "name": [
            "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rakhmetova", 
        "givenName": "A. A.", 
        "id": "sg:person.015265215715.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015265215715.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.434999.a", 
          "name": [
            "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bogoslovskaya", 
        "givenName": "O. A.", 
        "id": "sg:person.016062576315.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016062576315.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.434999.a", 
          "name": [
            "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Olkhovskaya", 
        "givenName": "I. P.", 
        "id": "sg:person.016660156715.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016660156715.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.434999.a", 
          "name": [
            "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhigach", 
        "givenName": "A. N.", 
        "id": "sg:person.01257745366.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257745366.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bioengineering Centre, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7 k. 1, 117312, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Bioengineering Centre, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7 k. 1, 117312, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ilyina", 
        "givenName": "A. V.", 
        "id": "sg:person.01232732226.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232732226.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bioengineering Centre, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7 k. 1, 117312, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Bioengineering Centre, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7 k. 1, 117312, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Varlamov", 
        "givenName": "V. P.", 
        "id": "sg:person.0631556207.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631556207.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia", 
          "id": "http://www.grid.ac/institutes/grid.434999.a", 
          "name": [
            "Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gluschenko", 
        "givenName": "N. N.", 
        "id": "sg:person.011553707615.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011553707615.19"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1134/s1995078014010042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032646880", 
          "https://doi.org/10.1134/s1995078014010042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1134/s199507801003016x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014364668", 
          "https://doi.org/10.1134/s199507801003016x"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-01", 
    "datePublishedReg": "2015-01-01", 
    "description": "The wound-healing properties of organic and inorganic nanoparticles, i.e., chitosan and copper nanoparticles, cointroduced into an ointment preparation, were investigated. When used individually in the ointment, copper oxide nanoparticles at a concentration of 0.002% and a level of oxidation of up to 90% and nanoparticles of chitosan at a concentration of 0.002% prepared from chitosan with a molecular weight of 10 kDa demonstrated the most profound wound-healing effect. The simultaneous introduction of chitosan and copper nanoparticles into the ointment composition led to a synergistic effect. The most pronounced wound healing was observed for complex ointment preparations containing Cu1Ox sample 2 copper nanoparticles at a concentration of 0.002% and chitosan nanoparticles synthesized from low-molecularweight chitosan (Mw 10 kDa) with a degree of deacetylation (DD) of 89% at a concentration of 0.002%. An additive effect was observed for the complex ointment in comparison with ointment preparations based on individual components. Similar antibacterial effects were observed in ointment preparations based on organic and inorganic nanoparticles.", 
    "genre": "article", 
    "id": "sg:pub.10.1134/s1995078015010164", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1403979", 
        "issn": [
          "2635-1676", 
          "2635-1684"
        ], 
        "name": "Nanobiotechnology Reports", 
        "publisher": "Pleiades Publishing", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1-2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "keywords": [
      "copper nanoparticles", 
      "inorganic nanoparticles", 
      "degree of deacetylation", 
      "copper oxide nanoparticles", 
      "nanoparticles of chitosan", 
      "level of oxidation", 
      "oxide nanoparticles", 
      "nanoparticles", 
      "chitosan nanoparticles", 
      "molecular weight", 
      "chitosan", 
      "synergistic effect", 
      "preparation", 
      "simultaneous introduction", 
      "ointment compositions", 
      "antibacterial effect", 
      "ointment preparations", 
      "wound healing properties", 
      "oxidation", 
      "concentration", 
      "individual components", 
      "antibacterial resistance", 
      "similar antibacterial effect", 
      "properties", 
      "composition", 
      "wound healing effect", 
      "deacetylation", 
      "concomitant action", 
      "effect", 
      "introduction", 
      "ointment", 
      "weight", 
      "resistance", 
      "components", 
      "degree", 
      "wound healing", 
      "example", 
      "comparison", 
      "action", 
      "additive effect", 
      "levels", 
      "healing"
    ], 
    "name": "Concomitant action of organic and inorganic nanoparticles in wound healing and antibacterial resistance: Chitosan and copper nanoparticles in an ointment as an example", 
    "pagination": "149-157", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1044204765"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1134/s1995078015010164"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1134/s1995078015010164", 
      "https://app.dimensions.ai/details/publication/pub.1044204765"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:40", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_673.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1134/s1995078015010164"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1134/s1995078015010164'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1134/s1995078015010164'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1134/s1995078015010164'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1134/s1995078015010164'


 

This table displays all metadata directly associated to this object as RDF triples.

152 TRIPLES      21 PREDICATES      69 URIs      59 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1134/s1995078015010164 schema:about anzsrc-for:03
2 anzsrc-for:0306
3 schema:author Na9eb24219bb14d7ea55b1a43b90f5231
4 schema:citation sg:pub.10.1134/s199507801003016x
5 sg:pub.10.1134/s1995078014010042
6 schema:datePublished 2015-01
7 schema:datePublishedReg 2015-01-01
8 schema:description The wound-healing properties of organic and inorganic nanoparticles, i.e., chitosan and copper nanoparticles, cointroduced into an ointment preparation, were investigated. When used individually in the ointment, copper oxide nanoparticles at a concentration of 0.002% and a level of oxidation of up to 90% and nanoparticles of chitosan at a concentration of 0.002% prepared from chitosan with a molecular weight of 10 kDa demonstrated the most profound wound-healing effect. The simultaneous introduction of chitosan and copper nanoparticles into the ointment composition led to a synergistic effect. The most pronounced wound healing was observed for complex ointment preparations containing Cu1Ox sample 2 copper nanoparticles at a concentration of 0.002% and chitosan nanoparticles synthesized from low-molecularweight chitosan (Mw 10 kDa) with a degree of deacetylation (DD) of 89% at a concentration of 0.002%. An additive effect was observed for the complex ointment in comparison with ointment preparations based on individual components. Similar antibacterial effects were observed in ointment preparations based on organic and inorganic nanoparticles.
9 schema:genre article
10 schema:isAccessibleForFree false
11 schema:isPartOf N3c34232ed1944c3b95369fb19ee42d77
12 N5931a5a32250457c8680aae2114855f3
13 sg:journal.1403979
14 schema:keywords action
15 additive effect
16 antibacterial effect
17 antibacterial resistance
18 chitosan
19 chitosan nanoparticles
20 comparison
21 components
22 composition
23 concentration
24 concomitant action
25 copper nanoparticles
26 copper oxide nanoparticles
27 deacetylation
28 degree
29 degree of deacetylation
30 effect
31 example
32 healing
33 individual components
34 inorganic nanoparticles
35 introduction
36 level of oxidation
37 levels
38 molecular weight
39 nanoparticles
40 nanoparticles of chitosan
41 ointment
42 ointment compositions
43 ointment preparations
44 oxidation
45 oxide nanoparticles
46 preparation
47 properties
48 resistance
49 similar antibacterial effect
50 simultaneous introduction
51 synergistic effect
52 weight
53 wound healing
54 wound healing effect
55 wound healing properties
56 schema:name Concomitant action of organic and inorganic nanoparticles in wound healing and antibacterial resistance: Chitosan and copper nanoparticles in an ointment as an example
57 schema:pagination 149-157
58 schema:productId N7fe7c055ad834b42bc498d124dc8900d
59 Nd447cd07dd5142109f0c80ac85898470
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044204765
61 https://doi.org/10.1134/s1995078015010164
62 schema:sdDatePublished 2022-10-01T06:40
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N0462b24831be4efc985c95bfd95bdb73
65 schema:url https://doi.org/10.1134/s1995078015010164
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N0462b24831be4efc985c95bfd95bdb73 schema:name Springer Nature - SN SciGraph project
70 rdf:type schema:Organization
71 N33cf51151c99409b8f1e2c2c0542773a rdf:first sg:person.01232732226.93
72 rdf:rest N55df5680f1474026a746d830455e3aef
73 N3c34232ed1944c3b95369fb19ee42d77 schema:issueNumber 1-2
74 rdf:type schema:PublicationIssue
75 N4981cb26e93847688f4bc908f5fce3dd rdf:first sg:person.011553707615.19
76 rdf:rest rdf:nil
77 N55df5680f1474026a746d830455e3aef rdf:first sg:person.0631556207.02
78 rdf:rest N4981cb26e93847688f4bc908f5fce3dd
79 N5931a5a32250457c8680aae2114855f3 schema:volumeNumber 10
80 rdf:type schema:PublicationVolume
81 N76c02958807d4b7bb33c853a38137c8b rdf:first sg:person.016062576315.53
82 rdf:rest Nc53f482cd20d40209ed90168570f2c0f
83 N7fe7c055ad834b42bc498d124dc8900d schema:name dimensions_id
84 schema:value pub.1044204765
85 rdf:type schema:PropertyValue
86 N9d8694d3b8874c7981e688a8e3d60e47 rdf:first sg:person.01257745366.40
87 rdf:rest N33cf51151c99409b8f1e2c2c0542773a
88 Na9eb24219bb14d7ea55b1a43b90f5231 rdf:first sg:person.015265215715.24
89 rdf:rest N76c02958807d4b7bb33c853a38137c8b
90 Nc53f482cd20d40209ed90168570f2c0f rdf:first sg:person.016660156715.09
91 rdf:rest N9d8694d3b8874c7981e688a8e3d60e47
92 Nd447cd07dd5142109f0c80ac85898470 schema:name doi
93 schema:value 10.1134/s1995078015010164
94 rdf:type schema:PropertyValue
95 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
96 schema:name Chemical Sciences
97 rdf:type schema:DefinedTerm
98 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
99 schema:name Physical Chemistry (incl. Structural)
100 rdf:type schema:DefinedTerm
101 sg:journal.1403979 schema:issn 2635-1676
102 2635-1684
103 schema:name Nanobiotechnology Reports
104 schema:publisher Pleiades Publishing
105 rdf:type schema:Periodical
106 sg:person.011553707615.19 schema:affiliation grid-institutes:grid.434999.a
107 schema:familyName Gluschenko
108 schema:givenName N. N.
109 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011553707615.19
110 rdf:type schema:Person
111 sg:person.01232732226.93 schema:affiliation grid-institutes:grid.4886.2
112 schema:familyName Ilyina
113 schema:givenName A. V.
114 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232732226.93
115 rdf:type schema:Person
116 sg:person.01257745366.40 schema:affiliation grid-institutes:grid.434999.a
117 schema:familyName Zhigach
118 schema:givenName A. N.
119 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257745366.40
120 rdf:type schema:Person
121 sg:person.015265215715.24 schema:affiliation grid-institutes:grid.434999.a
122 schema:familyName Rakhmetova
123 schema:givenName A. A.
124 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015265215715.24
125 rdf:type schema:Person
126 sg:person.016062576315.53 schema:affiliation grid-institutes:grid.434999.a
127 schema:familyName Bogoslovskaya
128 schema:givenName O. A.
129 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016062576315.53
130 rdf:type schema:Person
131 sg:person.016660156715.09 schema:affiliation grid-institutes:grid.434999.a
132 schema:familyName Olkhovskaya
133 schema:givenName I. P.
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016660156715.09
135 rdf:type schema:Person
136 sg:person.0631556207.02 schema:affiliation grid-institutes:grid.4886.2
137 schema:familyName Varlamov
138 schema:givenName V. P.
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631556207.02
140 rdf:type schema:Person
141 sg:pub.10.1134/s199507801003016x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014364668
142 https://doi.org/10.1134/s199507801003016x
143 rdf:type schema:CreativeWork
144 sg:pub.10.1134/s1995078014010042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032646880
145 https://doi.org/10.1134/s1995078014010042
146 rdf:type schema:CreativeWork
147 grid-institutes:grid.434999.a schema:alternateName Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia
148 schema:name Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Leninskii pr. 38 k. 2, 119334, Moscow, Russia
149 rdf:type schema:Organization
150 grid-institutes:grid.4886.2 schema:alternateName Bioengineering Centre, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7 k. 1, 117312, Moscow, Russia
151 schema:name Bioengineering Centre, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7 k. 1, 117312, Moscow, Russia
152 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...