Knoevenagel Reactions of Indole-3-carbaldehyde. Synthesis of 3-Substituted Indole Derivatives View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-12

AUTHORS

V. D. Dyachenko, I. O. Matusov, I. V. Dyachenko, V. G. Nenajdenko

ABSTRACT

The Knoevenagel condensations of 1H-indole-3-carbaldehyde with various CH acids gave a number of substituted 3-(1H-indol-3-yl)acrylonitriles and acrylamides which were alkylated to afford the corresponding N-alkyl derivatives. The latter were used as Michael acceptors in the synthesis of 4H-pyran, pyridine, 5,6,7,8-tetrahydroquinoline, and [1,3]thiazolo[3,2-a]pyridine derivatives containing an indole fragment.

PAGES

1777-1784

References to SciGraph publications

  • 2018-04. A New Approach to the Synthesis of Functional Derivatives of 3-(4-Pyridinyl)-1H-indole and 4-(1H-Indol-3-yl)thieno[2,3-b]pyridine in RUSSIAN JOURNAL OF GENERAL CHEMISTRY
  • 2006-01. New approach to the synthesis of substituted 5-arylcarbamoyl-3-cyano-6-methylpyridine-2(1h)-thiones. Molecular and crystal structure of 2-allylthio-3-cyano-5-(2-methoxyphenylcarbamoyl)-6-methyl-4-(5-methyl-2-furyl)-1,4-dihydropyridine in CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • 2001-09. Convenient Methods for Synthesis of Partially Hydrogenated Benzothiazol-2-ylpyridines in CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • 2006-07. Synthesis and unusual reaction of piperidinium 3-cyano-5-ethoxycarbonyl-4-(1H-indol-3-yl)-6-methyl-1,4-dihydropyridine-2-thiolate with glacial acetic acid in RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • 2008-07. Synthesis and alkylation of n(3)-aryl-n(5)-phenyl-6-amino-4-aryl(2-furyl)-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamide in CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • 2018-02. Modern Trends of Organic Chemistry in Russian Universities in RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • 2013-01. Synthesis of pyrido[2',3':3,4]cyclopenta-[1,2-c]isoquinoline, a new heterocyclic system in CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • 2007-01. N-hetaryl-2-cyanoacetamides in the synthesis of substituted (E)-N-hetaryl-2-cyanoacrylamides, (E)-N-alkyl-N-hetaryl-2-cyanoacrylamides, and 6-amino-2-oxo-4-phenyl-1-(pyridin-2-yl)-1,2-dihydropyridine-3,5-dicarbonitriles in RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • 2017-09. Organic chemistry. History and mutual relations of universities of Russia in RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • 2015-10. Microwave synthesis of 2-[(E)-2-(1H-indol-3-yl)vinyl]hetarenes in CHEMISTRY OF HETEROCYCLIC COMPOUNDS
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    http://scigraph.springernature.com/pub.10.1134/s1070428018120060

    DOI

    http://dx.doi.org/10.1134/s1070428018120060

    DIMENSIONS

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