Synthesis, Structure, and Antiproliferative Activity of trans-Palladium(II) Complexes with Tetrazol-2-ylacetic Acid Derivatives View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-11

AUTHORS

E. A. Popova, O. V. Mikolaichuk, A. V. Protas, A. V. Mukhametshina, G. K. Ovsepyan, G. L. Starova, R. V. Suezov, A. V. Fonin, R. E. Trifonov

ABSTRACT

A series of trans-palladium(II) complexes (trans-[PdCl2L2], L = ethyl 5-R-2H-tetrazol-2-ylacetate, 5-R-2H-tetrazol-2-ylacetamides, R = Me, Ph) has been synthesized, and their structure has been proved by 1H and 13C–{1H} NMR and high-resolution mass spectra and X-ray analysis. Antiproliferative activity of the synthesized complexes has been determined, and the mechanism of their interaction with DNA has been studied by UV and CD spectroscopy. More... »

PAGES

2354-2358

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s1070363218110178

DOI

http://dx.doi.org/10.1134/s1070363218110178

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110933776


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