Synthesis of New Functionalized 1,4-Dihydroquinolines and Pyrimido[4,5-b]quinolines View Full Text


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Article Info

DATE

2017-12

AUTHORS

F. Khoramdelan, A. Davoodnia, M. R. Bozorgmehr, M. Ebrahimi

ABSTRACT

The reaction of N-alkylisatoic anhydrides with malononitrile in pyridine led to formation of new 2-amino-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carbonitriles. Following treatment of these compounds with an excess of aliphatic carboxylic acids in the presence of POCl3 under reflux gave novel 2,10-dialkylpyrimido[4,5-b]quinoline-4,5(3H,10H)-diones with high yields. It is probable that synthesis of the latter products proceed via the tandem intramolecular Pinner–Dimroth rearrangement. All synthesized compounds were characterized by spectral and microanalytical data. More... »

PAGES

2961-2965

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s1070363217120386

DOI

http://dx.doi.org/10.1134/s1070363217120386

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101041441


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