Expression of the β1 Adrenergic Receptor Gene (ADRB1) in the Myocardium of Patients with Chronic Heart Failure View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-11-18

AUTHORS

E. F. Muslimova, T. Yu. Rebrova, D. S. Kondratieva, E. L. Sonduev, B. N. Kozlov, S. A. Afanasiev

ABSTRACT

An analysis of the level of relative expression of the β1 adrenergic receptor ADRB1 gene in the myocardium of 78 patients with chronic heart failure against the background of the combined development of ischemic heart disease and arterial hypertension was carried out. A significant decrease in the level of ADRB1 gene expression was revealed in patients with left ventricular hypertrophy. In the considered cohort, the expression level of the ADRB1 gene did not depend on the functional class of heart failure. The ADRB1 relative expression was higher in patients taking acetylsalicylic acid preparations, but did not show a significant association with the use of β blockers or ACE inhibitors. More... »

PAGES

1304-1311

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s1022795421110089

DOI

http://dx.doi.org/10.1134/s1022795421110089

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1142678916


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