Micro-RNA in Patients with Carotid Atherosclerosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-12

AUTHORS

A. A. Raskurazhev, M. M. Tanashyan, A. A. Shabalina, P. I. Kuznetsova, A. A. Kornilova, A. G. Burmak

ABSTRACT

Atherosclerosis is a multifactorial disease and one of the leading causes of ischaemic stroke. In recent years, microRNA has become an important factor to consider in the pathogenesis of atherosclerosis. MicroRNAs are non-coding RNA sequences that are divided into proatherogenic and atheroprotective. This study evaluated the leukocyte expression of certain microRNAs (miR-126-(5p/3p), miR-29a-(5p/3p), miR-33a-5p and miR-21-(5p/3p)) in patients with carotid atherosclerosis. Statistically significant differences were found between patient groups in regard to the molecular levels, as well as correlations between several microRNAs. This indicates the potential use of microRNA in diagnosis and treatment, and confirms the role of microRNAs as important regulators of carotid atherosclerosis. More... »

PAGES

880-885

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s0362119720080113

DOI

http://dx.doi.org/10.1134/s0362119720080113

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1135553970


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