Application of Array-Based Oligonucleotides for Synthesis of Genetic Designs View Full Text


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Article Info

DATE

2021-07

AUTHORS

A. N. Sinyakov, V. A. Ryabinin, E. V. Kostina

ABSTRACT

The application of array-based oligonucleotides in biological studies is described. These oligonucleotides are mainly used to design large libraries of various nucleotide sequences, which are applied to study protein-nucleic acid interactions, splicing, transcription, translation, and other regulatory processes in mammalian, yeast, and bacterial systems. The application of gene libraries generated by array-based nucleotides along with advanced methods of the combination of DNA duplexes will make it possible to obtain complex genetic designs for synthetic biology. More... »

PAGES

487-500

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