Long Noncoding RNAs and Their Role in Oncogenesis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-11

AUTHORS

I. V. Bure, E. B. Kuznetsova, D. V. Zaletaev

ABSTRACT

The noncoding part of the human genome, which was previously considered nonfunctional or junk DNA, has been the subject of extensive research this decade. Nevertheless, long noncoding RNAs still represent one of the least investigated fields because of their complexity, multiplicity, and diversity. While some long noncoding RNAs have been characterized fairly well, the functions of many others remain poorly understood. Long noncoding RNAs play an essential role in the regulation of gene expression in all tissues and on all developmental stages. They are involved in a number of signaling pathways, and their aberrant functioning can be pathogenic. This review aims to summarize current state-of-the-art structures of these transcripts in this research field, their genomic localization, their functions, and underlying mechanisms. It also focuses on cancer-associated aberrations of long noncoding RNAs, as well as on prospects of their application in tumor diagnostics and therapy. Examples of decreasing the levels of oncogenic long noncoding RNAs via silencing with short interfering RNAs, antisense oligonucleotides, or low molecular-weight inhibitors are also described. More... »

PAGES

787-798

References to SciGraph publications

  • 2011-12. Non-coding RNAs in human disease in NATURE REVIEWS GENETICS
  • 2017-04. Perspectives of long non-coding RNAs in cancer in MOLECULAR BIOLOGY REPORTS
  • 2003-09. MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer in ONCOGENE
  • 2015-09. Long Noncoding RNA MALAT-1 Can Predict Metastasis and a Poor Prognosis: a Meta-Analysis in PATHOLOGY & ONCOLOGY RESEARCH
  • 1991-01. A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome in NATURE
  • 2014-12. The functional role of long non-coding RNAs and epigenetics in BIOLOGICAL PROCEDURES ONLINE
  • 2012-09. Landscape of transcription in human cells in NATURE
  • 2013-05. Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies in JOURNAL OF NEURO-ONCOLOGY
  • 2014-12. Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells in TUMOR BIOLOGY
  • 2013-06. New functions of small nucleolar RNAs in BIOCHEMISTRY (MOSCOW)
  • 2014-06. The rise of regulatory RNA in NATURE REVIEWS GENETICS
  • 2011-08. Xist regulation and function eXplored in HUMAN GENETICS
  • 2013-03. The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage in CELL RESEARCH
  • 2010-12. Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells in NATURE GENETICS
  • 2018-12. LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells in CANCER CELL INTERNATIONAL
  • 2013-03. Structure and function of long noncoding RNAs in epigenetic regulation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-03. HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer in ONCOGENE
  • 2015-03. The landscape of long noncoding RNAs in the human transcriptome in NATURE GENETICS
  • 2017-12. The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling in MOLECULAR CANCER
  • 2000-05. Genomic imprinting: Silence across the border in NATURE
  • 2012-02. Modular regulatory principles of large non-coding RNAs in NATURE
  • 2016-12. Long noncoding RNAs in cancer: mechanisms of action and technological advancements in MOLECULAR CANCER
  • 2018-02. Gene regulation of mammalian long non-coding RNA in MOLECULAR GENETICS AND GENOMICS
  • 2014-11. Cisplatin and paclitaxel target significant long noncoding RNAs in laryngeal squamous cell carcinoma in MEDICAL ONCOLOGY
  • 2015-01. Discovery and annotation of long noncoding RNAs in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2010-04-15. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis in NATURE
  • 2017-01. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide in NATURE
  • 2016-01. Unique features of long non-coding RNA biogenesis and function in NATURE REVIEWS GENETICS
  • 2016-02. Role of non-coding sequence variants in cancer in NATURE REVIEWS GENETICS
  • 2016-06. Roles for long non-coding RNAs in physiology and disease in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 2015-07. Control of mammalian gene expression by selective mRNA export in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2013-07. MALAT1 — a paradigm for long noncoding RNA function in cancer in JOURNAL OF MOLECULAR MEDICINE
  • 2007-11. Noncoding RNAs in BIOCHEMISTRY (MOSCOW)
  • 2015-07. A role of long noncoding RNAs in carcinogenesis in MOLECULAR BIOLOGY
  • 2017. History, Discovery, and Classification of lncRNAs in LONG NON CODING RNA BIOLOGY
  • 2015-12. Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution in GENOME BIOLOGY
  • 2013-03. Natural RNA circles function as efficient microRNA sponges in NATURE
  • 2013-01. Peptidomic discovery of short open reading frame–encoded peptides in human cells in NATURE CHEMICAL BIOLOGY
  • 2011-02. Genomewide characterization of non-polyadenylated RNAs in GENOME BIOLOGY
  • 2015-12. Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin in GENOME BIOLOGY
  • 2016-05. LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer in ONCOGENE
  • 2013-12. Divergent transcription is associated with promoters of transcriptional regulators in BMC GENOMICS
  • 2009-03. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals in NATURE
  • 2013-11. RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • Journal

    TITLE

    Molecular Biology

    ISSUE

    6

    VOLUME

    52

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1134/s0026893318060031

    DOI

    http://dx.doi.org/10.1134/s0026893318060031

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1110893834


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Sechenov University", 
              "id": "https://www.grid.ac/institutes/grid.448878.f", 
              "name": [
                "Institute of Molecular Medicine, Sechenov First Moscow State Medical University (Sechenov University), 119146, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bure", 
            "givenName": "I. V.", 
            "id": "sg:person.01030340530.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030340530.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Sechenov University", 
              "id": "https://www.grid.ac/institutes/grid.448878.f", 
              "name": [
                "Institute of Molecular Medicine, Sechenov First Moscow State Medical University (Sechenov University), 119146, Moscow, Russia", 
                "Research Center for Medical Genetics, 115522, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kuznetsova", 
            "givenName": "E. B.", 
            "id": "sg:person.014202764377.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014202764377.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Sechenov University", 
              "id": "https://www.grid.ac/institutes/grid.448878.f", 
              "name": [
                "Institute of Molecular Medicine, Sechenov First Moscow State Medical University (Sechenov University), 119146, Moscow, Russia", 
                "Research Center for Medical Genetics, 115522, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zaletaev", 
            "givenName": "D. V.", 
            "id": "sg:person.01371337133.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371337133.89"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1242/dev.048181", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000265707"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2014.06.031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001695700"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bies.20544", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002385421"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gks915", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002477416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1192002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002615413"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1192002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002615413"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-015-0586-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002714533", 
              "https://doi.org/10.1186/s13059-015-0586-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-015-0586-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002714533", 
              "https://doi.org/10.1186/s13059-015-0586-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tig.2011.04.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002752442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11233", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003047559", 
              "https://doi.org/10.1038/nature11233"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2008.05.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003133361"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2013.06.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004160308"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12032-014-0246-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004905362", 
              "https://doi.org/10.1007/s12032-014-0246-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12032-014-0246-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004905362", 
              "https://doi.org/10.1007/s12032-014-0246-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-016-0530-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007043269", 
              "https://doi.org/10.1186/s12943-016-0530-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-014-2453-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008007885", 
              "https://doi.org/10.1007/s13277-014-2453-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1410622111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008290206"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2015.04.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008627709"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gks1099", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008917836"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1003368", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009452377"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.6026/97320630011512", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009808477"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2015.09.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010021209"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1242/dev.057778", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010608362"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1134/s002689331504010x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010844750", 
              "https://doi.org/10.1134/s002689331504010x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg3074", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010854443", 
              "https://doi.org/10.1038/nrg3074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-014-0570-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013626227", 
              "https://doi.org/10.1186/s13059-014-0570-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-014-0570-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013626227", 
              "https://doi.org/10.1186/s13059-014-0570-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2013.12.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013778106"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gr.132159.111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013862605"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/cancers5020462", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015395997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg3722", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015493329", 
              "https://doi.org/10.1038/nrg3722"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2014.03.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015863305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1261/rna.053561.115", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016307390"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/147323001103900608", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016644921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/147323001103900608", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016644921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-11-1021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016692100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08975", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017276958", 
              "https://doi.org/10.1038/nature08975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08975", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017276958", 
              "https://doi.org/10.1038/nature08975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08975", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017276958", 
              "https://doi.org/10.1038/nature08975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pcbi.1003517", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017398150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2011.08.018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017411851"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1163802", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018805109"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.celrep.2014.12.026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019403338"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2014.07.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020140427"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2014.07.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020140427"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.aad4076", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021434601"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1221904110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021469401"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1261/rna.028639.111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021585985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1163853", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023538121"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1163853", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023538121"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2164-14-914", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023821911", 
              "https://doi.org/10.1186/1471-2164-14-914"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.81.17.5523", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025273632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tibs.2016.07.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025366230"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkv1252", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025742710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1134/s0006297913060096", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026340403", 
              "https://doi.org/10.1134/s0006297913060096"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2011.06.051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026593876"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm4010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026656029", 
              "https://doi.org/10.1038/nrm4010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fgene.2014.00193", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026982747"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2013.05.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027005696"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbagrm.2014.08.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027060341"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbagrm.2014.04.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027357450"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.c000409200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027431710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2016.01.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027468419"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2016.01.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027468419"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3192", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028060819", 
              "https://doi.org/10.1038/ng.3192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2013.05.101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028355516"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.01673-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029208024"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygeno.2016.07.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029221138"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb.2942", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029680698", 
              "https://doi.org/10.1038/nsmb.2942"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00109-013-1028-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030769572", 
              "https://doi.org/10.1007/s00109-013-1028-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature21034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031063077", 
              "https://doi.org/10.1038/nature21034"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkv1206", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031308449"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2012.06.027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031672630"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio.1120", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032287932", 
              "https://doi.org/10.1038/nchembio.1120"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1811209", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032388708"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2014.11.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033752240"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gku988", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033786032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1590/s1677-55382010000600003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033881991"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbagrm.2015.07.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033889442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1515/bmc-2012-0050", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034270004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/path.2638", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034572882"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/path.2638", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034572882"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0077468", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035406489"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2012.193", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035663321", 
              "https://doi.org/10.1038/onc.2012.193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/cancers7040884", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035876933"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2015.340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036542018", 
              "https://doi.org/10.1038/onc.2015.340"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-011-1008-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036972520", 
              "https://doi.org/10.1007/s00439-011-1008-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00439-011-1008-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036972520", 
              "https://doi.org/10.1007/s00439-011-1008-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fncel.2013.00168", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036979725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm3679", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037346264", 
              "https://doi.org/10.1038/nrm3679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkw162", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038178960"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35013178", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038369196", 
              "https://doi.org/10.1038/35013178"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35013178", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038369196", 
              "https://doi.org/10.1038/35013178"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.270959.115", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038440770"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12253-015-9960-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038444441", 
              "https://doi.org/10.1007/s12253-015-9960-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddq353", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038526980"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddq353", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038526980"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11060-013-1084-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038667462", 
              "https://doi.org/10.1007/s11060-013-1084-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1206928", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039234308", 
              "https://doi.org/10.1038/sj.onc.1206928"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1206928", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039234308", 
              "https://doi.org/10.1038/sj.onc.1206928"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cr.2012.164", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039241524", 
              "https://doi.org/10.1038/cr.2012.164"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ijc.29484", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039626061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fgene.2015.00145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039756367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gde.2007.08.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040814451"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg.2015.10", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041005829", 
              "https://doi.org/10.1038/nrg.2015.10"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2011-12-2-r16", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041437656", 
              "https://doi.org/10.1186/gb-2011-12-2-r16"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajpath.2012.08.042", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041552949"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2011.09.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041816546"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mrrev.2014.11.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042503749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbcan.2015.07.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043012974"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.234419.113", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043027672"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/ijms17050702", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043473987"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0583-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043740862", 
              "https://doi.org/10.1186/s12943-017-0583-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0583-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043740862", 
              "https://doi.org/10.1186/s12943-017-0583-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2014.09.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043923311"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1091/mbc.e13-04-0223", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044550026"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1134/s0006297907110016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044575410", 
              "https://doi.org/10.1134/s0006297907110016"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.10.1.28", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044746062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.710", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045439193", 
              "https://doi.org/10.1038/ng.710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00424-016-1804-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048289383", 
              "https://doi.org/10.1007/s00424-016-1804-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2013.01.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048619187"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/sqb.2004.69.55", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048917730"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/sqb.2004.69.55", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048917730"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature10887", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049083762", 
              "https://doi.org/10.1038/nature10887"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.semcdb.2011.01.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049292854"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1480-9222-16-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049820420", 
              "https://doi.org/10.1186/1480-9222-16-11"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1480-9222-16-11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049820420", 
              "https://doi.org/10.1186/1480-9222-16-11"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev-biochem-051410-092902", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050213498"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11993", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050833467", 
              "https://doi.org/10.1038/nature11993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tig.2014.01.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051025381"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07672", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051133532", 
              "https://doi.org/10.1038/nature07672"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000430387", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051143825"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb.2480", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051164459", 
              "https://doi.org/10.1038/nsmb.2480"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2007.05.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051644950"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.celrep.2015.04.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052379921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2016/9085195", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052580501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg.2015.17", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053266182", 
              "https://doi.org/10.1038/nrg.2015.17"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/349038a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053275082", 
              "https://doi.org/10.1038/349038a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/15476286.2015.1062960", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058403004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2741/4472", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070916655"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/ol.2016.4901", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071527663"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2012.2219", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532225"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2012.2219", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532225"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4161/rna.19985", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072309964"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075042868", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078565308", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078763310", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079087127", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bib/bbx042", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084178171"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7150/ijbs.16968", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084480835"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11033-017-4103-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084519037", 
              "https://doi.org/10.1007/s11033-017-4103-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11033-017-4103-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084519037", 
              "https://doi.org/10.1007/s11033-017-4103-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2741/4572", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084649861"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bies.201600264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085417232"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2017/7243968", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085705349"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bst20160376", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086052396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bst20160376", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086052396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-16-2634", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090692517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/cas.13342", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090996305"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-981-10-5203-3_1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091216765", 
              "https://doi.org/10.1007/978-981-10-5203-3_1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00438-017-1370-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091569925", 
              "https://doi.org/10.1007/s00438-017-1370-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/sciadv.aao2110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091975604"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gde.2017.10.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092243717"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.gde.2017.10.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092243717"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.semcdb.2017.11.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092685568"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12935-018-0540-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101621322", 
              "https://doi.org/10.1186/s12935-018-0540-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12935-018-0540-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101621322", 
              "https://doi.org/10.1186/s12935-018-0540-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12935-018-0540-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101621322", 
              "https://doi.org/10.1186/s12935-018-0540-0"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-11", 
        "datePublishedReg": "2018-11-01", 
        "description": "The noncoding part of the human genome, which was previously considered nonfunctional or junk DNA, has been the subject of extensive research this decade. Nevertheless, long noncoding RNAs still represent one of the least investigated fields because of their complexity, multiplicity, and diversity. While some long noncoding RNAs have been characterized fairly well, the functions of many others remain poorly understood. Long noncoding RNAs play an essential role in the regulation of gene expression in all tissues and on all developmental stages. They are involved in a number of signaling pathways, and their aberrant functioning can be pathogenic. This review aims to summarize current state-of-the-art structures of these transcripts in this research field, their genomic localization, their functions, and underlying mechanisms. It also focuses on cancer-associated aberrations of long noncoding RNAs, as well as on prospects of their application in tumor diagnostics and therapy. Examples of decreasing the levels of oncogenic long noncoding RNAs via silencing with short interfering RNAs, antisense oligonucleotides, or low molecular-weight inhibitors are also described.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1134/s0026893318060031", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1356887", 
            "issn": [
              "0026-8933", 
              "1608-3245"
            ], 
            "name": "Molecular Biology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "52"
          }
        ], 
        "name": "Long Noncoding RNAs and Their Role in Oncogenesis", 
        "pagination": "787-798", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "32b1a9a25b223b5b93b0326b25bd2c0e673cc37cfb2d271a1300552023c98272"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1134/s0026893318060031"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1110893834"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1134/s0026893318060031", 
          "https://app.dimensions.ai/details/publication/pub.1110893834"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T08:27", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000301_0000000301/records_32635_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1134%2FS0026893318060031"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1134/s0026893318060031'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1134/s0026893318060031'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1134/s0026893318060031'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1134/s0026893318060031'


     

    This table displays all metadata directly associated to this object as RDF triples.

    548 TRIPLES      21 PREDICATES      171 URIs      19 LITERALS      7 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1134/s0026893318060031 schema:about anzsrc-for:06
    2 anzsrc-for:0604
    3 schema:author Ndf672613b0cb4f47a15b398152cbe085
    4 schema:citation sg:pub.10.1007/978-981-10-5203-3_1
    5 sg:pub.10.1007/s00109-013-1028-y
    6 sg:pub.10.1007/s00424-016-1804-y
    7 sg:pub.10.1007/s00438-017-1370-9
    8 sg:pub.10.1007/s00439-011-1008-7
    9 sg:pub.10.1007/s11033-017-4103-6
    10 sg:pub.10.1007/s11060-013-1084-8
    11 sg:pub.10.1007/s12032-014-0246-7
    12 sg:pub.10.1007/s12253-015-9960-5
    13 sg:pub.10.1007/s13277-014-2453-4
    14 sg:pub.10.1038/349038a0
    15 sg:pub.10.1038/35013178
    16 sg:pub.10.1038/cr.2012.164
    17 sg:pub.10.1038/nature07672
    18 sg:pub.10.1038/nature08975
    19 sg:pub.10.1038/nature10887
    20 sg:pub.10.1038/nature11233
    21 sg:pub.10.1038/nature11993
    22 sg:pub.10.1038/nature21034
    23 sg:pub.10.1038/nchembio.1120
    24 sg:pub.10.1038/ng.3192
    25 sg:pub.10.1038/ng.710
    26 sg:pub.10.1038/nrg.2015.10
    27 sg:pub.10.1038/nrg.2015.17
    28 sg:pub.10.1038/nrg3074
    29 sg:pub.10.1038/nrg3722
    30 sg:pub.10.1038/nrm3679
    31 sg:pub.10.1038/nrm4010
    32 sg:pub.10.1038/nsmb.2480
    33 sg:pub.10.1038/nsmb.2942
    34 sg:pub.10.1038/onc.2012.193
    35 sg:pub.10.1038/onc.2015.340
    36 sg:pub.10.1038/sj.onc.1206928
    37 sg:pub.10.1134/s0006297907110016
    38 sg:pub.10.1134/s0006297913060096
    39 sg:pub.10.1134/s002689331504010x
    40 sg:pub.10.1186/1471-2164-14-914
    41 sg:pub.10.1186/1480-9222-16-11
    42 sg:pub.10.1186/gb-2011-12-2-r16
    43 sg:pub.10.1186/s12935-018-0540-0
    44 sg:pub.10.1186/s12943-016-0530-6
    45 sg:pub.10.1186/s12943-017-0583-1
    46 sg:pub.10.1186/s13059-014-0570-4
    47 sg:pub.10.1186/s13059-015-0586-4
    48 https://app.dimensions.ai/details/publication/pub.1075042868
    49 https://app.dimensions.ai/details/publication/pub.1078565308
    50 https://app.dimensions.ai/details/publication/pub.1078763310
    51 https://app.dimensions.ai/details/publication/pub.1079087127
    52 https://doi.org/10.1002/bies.201600264
    53 https://doi.org/10.1002/bies.20544
    54 https://doi.org/10.1002/ijc.29484
    55 https://doi.org/10.1002/path.2638
    56 https://doi.org/10.1016/j.ajpath.2012.08.042
    57 https://doi.org/10.1016/j.bbagrm.2014.04.009
    58 https://doi.org/10.1016/j.bbagrm.2014.08.012
    59 https://doi.org/10.1016/j.bbagrm.2015.07.017
    60 https://doi.org/10.1016/j.bbcan.2015.07.001
    61 https://doi.org/10.1016/j.bbrc.2013.05.101
    62 https://doi.org/10.1016/j.ccell.2014.09.014
    63 https://doi.org/10.1016/j.ccell.2015.09.006
    64 https://doi.org/10.1016/j.ccr.2014.07.009
    65 https://doi.org/10.1016/j.cell.2007.05.022
    66 https://doi.org/10.1016/j.cell.2011.06.051
    67 https://doi.org/10.1016/j.cell.2011.09.028
    68 https://doi.org/10.1016/j.cell.2013.01.003
    69 https://doi.org/10.1016/j.cell.2013.05.028
    70 https://doi.org/10.1016/j.cell.2013.06.020
    71 https://doi.org/10.1016/j.cell.2014.03.008
    72 https://doi.org/10.1016/j.cell.2014.11.010
    73 https://doi.org/10.1016/j.celrep.2014.12.026
    74 https://doi.org/10.1016/j.celrep.2015.04.023
    75 https://doi.org/10.1016/j.febslet.2008.05.012
    76 https://doi.org/10.1016/j.gde.2007.08.001
    77 https://doi.org/10.1016/j.gde.2017.10.004
    78 https://doi.org/10.1016/j.molcel.2011.08.018
    79 https://doi.org/10.1016/j.molcel.2012.06.027
    80 https://doi.org/10.1016/j.molcel.2013.12.012
    81 https://doi.org/10.1016/j.molcel.2014.06.031
    82 https://doi.org/10.1016/j.molcel.2015.04.006
    83 https://doi.org/10.1016/j.molcel.2016.01.015
    84 https://doi.org/10.1016/j.mrrev.2014.11.003
    85 https://doi.org/10.1016/j.semcdb.2011.01.001
    86 https://doi.org/10.1016/j.semcdb.2017.11.012
    87 https://doi.org/10.1016/j.tibs.2016.07.003
    88 https://doi.org/10.1016/j.tig.2011.04.002
    89 https://doi.org/10.1016/j.tig.2014.01.004
    90 https://doi.org/10.1016/j.ygeno.2016.07.003
    91 https://doi.org/10.1042/bst20160376
    92 https://doi.org/10.1073/pnas.1221904110
    93 https://doi.org/10.1073/pnas.1410622111
    94 https://doi.org/10.1073/pnas.81.17.5523
    95 https://doi.org/10.1074/jbc.c000409200
    96 https://doi.org/10.1080/15476286.2015.1062960
    97 https://doi.org/10.1091/mbc.e13-04-0223
    98 https://doi.org/10.1093/bib/bbx042
    99 https://doi.org/10.1093/hmg/ddq353
    100 https://doi.org/10.1093/nar/gks1099
    101 https://doi.org/10.1093/nar/gks915
    102 https://doi.org/10.1093/nar/gku988
    103 https://doi.org/10.1093/nar/gkv1206
    104 https://doi.org/10.1093/nar/gkv1252
    105 https://doi.org/10.1093/nar/gkw162
    106 https://doi.org/10.1101/gad.1811209
    107 https://doi.org/10.1101/gad.234419.113
    108 https://doi.org/10.1101/gad.270959.115
    109 https://doi.org/10.1101/gr.132159.111
    110 https://doi.org/10.1101/sqb.2004.69.55
    111 https://doi.org/10.1111/cas.13342
    112 https://doi.org/10.1126/sciadv.aao2110
    113 https://doi.org/10.1126/science.1163802
    114 https://doi.org/10.1126/science.1163853
    115 https://doi.org/10.1126/science.1192002
    116 https://doi.org/10.1126/science.aad4076
    117 https://doi.org/10.1128/mcb.01673-13
    118 https://doi.org/10.1128/mcb.10.1.28
    119 https://doi.org/10.1146/annurev-biochem-051410-092902
    120 https://doi.org/10.1155/2016/9085195
    121 https://doi.org/10.1155/2017/7243968
    122 https://doi.org/10.1158/0008-5472.can-11-1021
    123 https://doi.org/10.1158/0008-5472.can-16-2634
    124 https://doi.org/10.1159/000430387
    125 https://doi.org/10.1177/147323001103900608
    126 https://doi.org/10.1242/dev.048181
    127 https://doi.org/10.1242/dev.057778
    128 https://doi.org/10.1261/rna.028639.111
    129 https://doi.org/10.1261/rna.053561.115
    130 https://doi.org/10.1371/journal.pcbi.1003517
    131 https://doi.org/10.1371/journal.pgen.1003368
    132 https://doi.org/10.1371/journal.pone.0077468
    133 https://doi.org/10.1515/bmc-2012-0050
    134 https://doi.org/10.1590/s1677-55382010000600003
    135 https://doi.org/10.2741/4472
    136 https://doi.org/10.2741/4572
    137 https://doi.org/10.3389/fgene.2014.00193
    138 https://doi.org/10.3389/fgene.2015.00145
    139 https://doi.org/10.3389/fncel.2013.00168
    140 https://doi.org/10.3390/cancers5020462
    141 https://doi.org/10.3390/cancers7040884
    142 https://doi.org/10.3390/ijms17050702
    143 https://doi.org/10.3892/ol.2016.4901
    144 https://doi.org/10.3892/or.2012.2219
    145 https://doi.org/10.4161/rna.19985
    146 https://doi.org/10.6026/97320630011512
    147 https://doi.org/10.7150/ijbs.16968
    148 schema:datePublished 2018-11
    149 schema:datePublishedReg 2018-11-01
    150 schema:description The noncoding part of the human genome, which was previously considered nonfunctional or junk DNA, has been the subject of extensive research this decade. Nevertheless, long noncoding RNAs still represent one of the least investigated fields because of their complexity, multiplicity, and diversity. While some long noncoding RNAs have been characterized fairly well, the functions of many others remain poorly understood. Long noncoding RNAs play an essential role in the regulation of gene expression in all tissues and on all developmental stages. They are involved in a number of signaling pathways, and their aberrant functioning can be pathogenic. This review aims to summarize current state-of-the-art structures of these transcripts in this research field, their genomic localization, their functions, and underlying mechanisms. It also focuses on cancer-associated aberrations of long noncoding RNAs, as well as on prospects of their application in tumor diagnostics and therapy. Examples of decreasing the levels of oncogenic long noncoding RNAs via silencing with short interfering RNAs, antisense oligonucleotides, or low molecular-weight inhibitors are also described.
    151 schema:genre research_article
    152 schema:inLanguage en
    153 schema:isAccessibleForFree false
    154 schema:isPartOf N2e832970568147f9a851e5f301dfd535
    155 N5864bc5c23e64070ba8f301db9bcad89
    156 sg:journal.1356887
    157 schema:name Long Noncoding RNAs and Their Role in Oncogenesis
    158 schema:pagination 787-798
    159 schema:productId N89f29c9315f2466e9f28731a9c1a4955
    160 Nd3c880b578864495874b96210a15bfc5
    161 Nffe55331be7140aebf30b254156b40b9
    162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110893834
    163 https://doi.org/10.1134/s0026893318060031
    164 schema:sdDatePublished 2019-04-11T08:27
    165 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    166 schema:sdPublisher N5e0aed1d2a9744478291f64fbb61a958
    167 schema:url https://link.springer.com/10.1134%2FS0026893318060031
    168 sgo:license sg:explorer/license/
    169 sgo:sdDataset articles
    170 rdf:type schema:ScholarlyArticle
    171 N2e832970568147f9a851e5f301dfd535 schema:volumeNumber 52
    172 rdf:type schema:PublicationVolume
    173 N2f2ed0d36c8241e0a2d39e14c735f0d1 rdf:first sg:person.014202764377.11
    174 rdf:rest Ncf75af36ef214c30b8f5cddc3170035f
    175 N5864bc5c23e64070ba8f301db9bcad89 schema:issueNumber 6
    176 rdf:type schema:PublicationIssue
    177 N5e0aed1d2a9744478291f64fbb61a958 schema:name Springer Nature - SN SciGraph project
    178 rdf:type schema:Organization
    179 N89f29c9315f2466e9f28731a9c1a4955 schema:name doi
    180 schema:value 10.1134/s0026893318060031
    181 rdf:type schema:PropertyValue
    182 Ncf75af36ef214c30b8f5cddc3170035f rdf:first sg:person.01371337133.89
    183 rdf:rest rdf:nil
    184 Nd3c880b578864495874b96210a15bfc5 schema:name dimensions_id
    185 schema:value pub.1110893834
    186 rdf:type schema:PropertyValue
    187 Ndf672613b0cb4f47a15b398152cbe085 rdf:first sg:person.01030340530.25
    188 rdf:rest N2f2ed0d36c8241e0a2d39e14c735f0d1
    189 Nffe55331be7140aebf30b254156b40b9 schema:name readcube_id
    190 schema:value 32b1a9a25b223b5b93b0326b25bd2c0e673cc37cfb2d271a1300552023c98272
    191 rdf:type schema:PropertyValue
    192 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    193 schema:name Biological Sciences
    194 rdf:type schema:DefinedTerm
    195 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    196 schema:name Genetics
    197 rdf:type schema:DefinedTerm
    198 sg:journal.1356887 schema:issn 0026-8933
    199 1608-3245
    200 schema:name Molecular Biology
    201 rdf:type schema:Periodical
    202 sg:person.01030340530.25 schema:affiliation https://www.grid.ac/institutes/grid.448878.f
    203 schema:familyName Bure
    204 schema:givenName I. V.
    205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030340530.25
    206 rdf:type schema:Person
    207 sg:person.01371337133.89 schema:affiliation https://www.grid.ac/institutes/grid.448878.f
    208 schema:familyName Zaletaev
    209 schema:givenName D. V.
    210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371337133.89
    211 rdf:type schema:Person
    212 sg:person.014202764377.11 schema:affiliation https://www.grid.ac/institutes/grid.448878.f
    213 schema:familyName Kuznetsova
    214 schema:givenName E. B.
    215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014202764377.11
    216 rdf:type schema:Person
    217 sg:pub.10.1007/978-981-10-5203-3_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091216765
    218 https://doi.org/10.1007/978-981-10-5203-3_1
    219 rdf:type schema:CreativeWork
    220 sg:pub.10.1007/s00109-013-1028-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1030769572
    221 https://doi.org/10.1007/s00109-013-1028-y
    222 rdf:type schema:CreativeWork
    223 sg:pub.10.1007/s00424-016-1804-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1048289383
    224 https://doi.org/10.1007/s00424-016-1804-y
    225 rdf:type schema:CreativeWork
    226 sg:pub.10.1007/s00438-017-1370-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091569925
    227 https://doi.org/10.1007/s00438-017-1370-9
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1007/s00439-011-1008-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036972520
    230 https://doi.org/10.1007/s00439-011-1008-7
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1007/s11033-017-4103-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084519037
    233 https://doi.org/10.1007/s11033-017-4103-6
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1007/s11060-013-1084-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038667462
    236 https://doi.org/10.1007/s11060-013-1084-8
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1007/s12032-014-0246-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004905362
    239 https://doi.org/10.1007/s12032-014-0246-7
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1007/s12253-015-9960-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038444441
    242 https://doi.org/10.1007/s12253-015-9960-5
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1007/s13277-014-2453-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008007885
    245 https://doi.org/10.1007/s13277-014-2453-4
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1038/349038a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053275082
    248 https://doi.org/10.1038/349038a0
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1038/35013178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038369196
    251 https://doi.org/10.1038/35013178
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1038/cr.2012.164 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039241524
    254 https://doi.org/10.1038/cr.2012.164
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1038/nature07672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051133532
    257 https://doi.org/10.1038/nature07672
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1038/nature08975 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017276958
    260 https://doi.org/10.1038/nature08975
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1038/nature10887 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049083762
    263 https://doi.org/10.1038/nature10887
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1038/nature11233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003047559
    266 https://doi.org/10.1038/nature11233
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1038/nature11993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050833467
    269 https://doi.org/10.1038/nature11993
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1038/nature21034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031063077
    272 https://doi.org/10.1038/nature21034
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1038/nchembio.1120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032287932
    275 https://doi.org/10.1038/nchembio.1120
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1038/ng.3192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028060819
    278 https://doi.org/10.1038/ng.3192
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1038/ng.710 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045439193
    281 https://doi.org/10.1038/ng.710
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1038/nrg.2015.10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041005829
    284 https://doi.org/10.1038/nrg.2015.10
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1038/nrg.2015.17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053266182
    287 https://doi.org/10.1038/nrg.2015.17
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1038/nrg3074 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010854443
    290 https://doi.org/10.1038/nrg3074
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1038/nrg3722 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015493329
    293 https://doi.org/10.1038/nrg3722
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1038/nrm3679 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037346264
    296 https://doi.org/10.1038/nrm3679
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1038/nrm4010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026656029
    299 https://doi.org/10.1038/nrm4010
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1038/nsmb.2480 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051164459
    302 https://doi.org/10.1038/nsmb.2480
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1038/nsmb.2942 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029680698
    305 https://doi.org/10.1038/nsmb.2942
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/onc.2012.193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035663321
    308 https://doi.org/10.1038/onc.2012.193
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/onc.2015.340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036542018
    311 https://doi.org/10.1038/onc.2015.340
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/sj.onc.1206928 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039234308
    314 https://doi.org/10.1038/sj.onc.1206928
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1134/s0006297907110016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044575410
    317 https://doi.org/10.1134/s0006297907110016
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1134/s0006297913060096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026340403
    320 https://doi.org/10.1134/s0006297913060096
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1134/s002689331504010x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010844750
    323 https://doi.org/10.1134/s002689331504010x
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1186/1471-2164-14-914 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023821911
    326 https://doi.org/10.1186/1471-2164-14-914
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1186/1480-9222-16-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049820420
    329 https://doi.org/10.1186/1480-9222-16-11
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1186/gb-2011-12-2-r16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041437656
    332 https://doi.org/10.1186/gb-2011-12-2-r16
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1186/s12935-018-0540-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101621322
    335 https://doi.org/10.1186/s12935-018-0540-0
    336 rdf:type schema:CreativeWork
    337 sg:pub.10.1186/s12943-016-0530-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007043269
    338 https://doi.org/10.1186/s12943-016-0530-6
    339 rdf:type schema:CreativeWork
    340 sg:pub.10.1186/s12943-017-0583-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043740862
    341 https://doi.org/10.1186/s12943-017-0583-1
    342 rdf:type schema:CreativeWork
    343 sg:pub.10.1186/s13059-014-0570-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013626227
    344 https://doi.org/10.1186/s13059-014-0570-4
    345 rdf:type schema:CreativeWork
    346 sg:pub.10.1186/s13059-015-0586-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002714533
    347 https://doi.org/10.1186/s13059-015-0586-4
    348 rdf:type schema:CreativeWork
    349 https://app.dimensions.ai/details/publication/pub.1075042868 schema:CreativeWork
    350 https://app.dimensions.ai/details/publication/pub.1078565308 schema:CreativeWork
    351 https://app.dimensions.ai/details/publication/pub.1078763310 schema:CreativeWork
    352 https://app.dimensions.ai/details/publication/pub.1079087127 schema:CreativeWork
    353 https://doi.org/10.1002/bies.201600264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085417232
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1002/bies.20544 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002385421
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1002/ijc.29484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039626061
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1002/path.2638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034572882
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1016/j.ajpath.2012.08.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041552949
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.1016/j.bbagrm.2014.04.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027357450
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.1016/j.bbagrm.2014.08.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027060341
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.1016/j.bbagrm.2015.07.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033889442
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1016/j.bbcan.2015.07.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043012974
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1016/j.bbrc.2013.05.101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028355516
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1016/j.ccell.2014.09.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043923311
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1016/j.ccell.2015.09.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010021209
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1016/j.ccr.2014.07.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020140427
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1016/j.cell.2007.05.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051644950
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1016/j.cell.2011.06.051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026593876
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1016/j.cell.2011.09.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041816546
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1016/j.cell.2013.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048619187
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1016/j.cell.2013.05.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027005696
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1016/j.cell.2013.06.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004160308
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1016/j.cell.2014.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015863305
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1016/j.cell.2014.11.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033752240
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1016/j.celrep.2014.12.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019403338
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1016/j.celrep.2015.04.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052379921
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1016/j.febslet.2008.05.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003133361
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1016/j.gde.2007.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040814451
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1016/j.gde.2017.10.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092243717
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1016/j.molcel.2011.08.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017411851
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1016/j.molcel.2012.06.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031672630
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1016/j.molcel.2013.12.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013778106
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1016/j.molcel.2014.06.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001695700
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1016/j.molcel.2015.04.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008627709
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1016/j.molcel.2016.01.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027468419
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1016/j.mrrev.2014.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042503749
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1016/j.semcdb.2011.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049292854
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1016/j.semcdb.2017.11.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092685568
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1016/j.tibs.2016.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025366230
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1016/j.tig.2011.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002752442
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1016/j.tig.2014.01.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051025381
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1016/j.ygeno.2016.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029221138
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1042/bst20160376 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086052396
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1073/pnas.1221904110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021469401
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1073/pnas.1410622111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008290206
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1073/pnas.81.17.5523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025273632
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1074/jbc.c000409200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027431710
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1080/15476286.2015.1062960 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058403004
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1091/mbc.e13-04-0223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044550026
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1093/bib/bbx042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084178171
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1093/hmg/ddq353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038526980
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1093/nar/gks1099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008917836
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1093/nar/gks915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002477416
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1093/nar/gku988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033786032
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.1093/nar/gkv1206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031308449
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.1093/nar/gkv1252 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025742710
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.1093/nar/gkw162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038178960
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.1101/gad.1811209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032388708
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.1101/gad.234419.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043027672
    464 rdf:type schema:CreativeWork
    465 https://doi.org/10.1101/gad.270959.115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038440770
    466 rdf:type schema:CreativeWork
    467 https://doi.org/10.1101/gr.132159.111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013862605
    468 rdf:type schema:CreativeWork
    469 https://doi.org/10.1101/sqb.2004.69.55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048917730
    470 rdf:type schema:CreativeWork
    471 https://doi.org/10.1111/cas.13342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090996305
    472 rdf:type schema:CreativeWork
    473 https://doi.org/10.1126/sciadv.aao2110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091975604
    474 rdf:type schema:CreativeWork
    475 https://doi.org/10.1126/science.1163802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018805109
    476 rdf:type schema:CreativeWork
    477 https://doi.org/10.1126/science.1163853 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023538121
    478 rdf:type schema:CreativeWork
    479 https://doi.org/10.1126/science.1192002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002615413
    480 rdf:type schema:CreativeWork
    481 https://doi.org/10.1126/science.aad4076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021434601
    482 rdf:type schema:CreativeWork
    483 https://doi.org/10.1128/mcb.01673-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029208024
    484 rdf:type schema:CreativeWork
    485 https://doi.org/10.1128/mcb.10.1.28 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044746062
    486 rdf:type schema:CreativeWork
    487 https://doi.org/10.1146/annurev-biochem-051410-092902 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050213498
    488 rdf:type schema:CreativeWork
    489 https://doi.org/10.1155/2016/9085195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052580501
    490 rdf:type schema:CreativeWork
    491 https://doi.org/10.1155/2017/7243968 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085705349
    492 rdf:type schema:CreativeWork
    493 https://doi.org/10.1158/0008-5472.can-11-1021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016692100
    494 rdf:type schema:CreativeWork
    495 https://doi.org/10.1158/0008-5472.can-16-2634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090692517
    496 rdf:type schema:CreativeWork
    497 https://doi.org/10.1159/000430387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051143825
    498 rdf:type schema:CreativeWork
    499 https://doi.org/10.1177/147323001103900608 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016644921
    500 rdf:type schema:CreativeWork
    501 https://doi.org/10.1242/dev.048181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000265707
    502 rdf:type schema:CreativeWork
    503 https://doi.org/10.1242/dev.057778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010608362
    504 rdf:type schema:CreativeWork
    505 https://doi.org/10.1261/rna.028639.111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021585985
    506 rdf:type schema:CreativeWork
    507 https://doi.org/10.1261/rna.053561.115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016307390
    508 rdf:type schema:CreativeWork
    509 https://doi.org/10.1371/journal.pcbi.1003517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017398150
    510 rdf:type schema:CreativeWork
    511 https://doi.org/10.1371/journal.pgen.1003368 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009452377
    512 rdf:type schema:CreativeWork
    513 https://doi.org/10.1371/journal.pone.0077468 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035406489
    514 rdf:type schema:CreativeWork
    515 https://doi.org/10.1515/bmc-2012-0050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034270004
    516 rdf:type schema:CreativeWork
    517 https://doi.org/10.1590/s1677-55382010000600003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033881991
    518 rdf:type schema:CreativeWork
    519 https://doi.org/10.2741/4472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070916655
    520 rdf:type schema:CreativeWork
    521 https://doi.org/10.2741/4572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084649861
    522 rdf:type schema:CreativeWork
    523 https://doi.org/10.3389/fgene.2014.00193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026982747
    524 rdf:type schema:CreativeWork
    525 https://doi.org/10.3389/fgene.2015.00145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039756367
    526 rdf:type schema:CreativeWork
    527 https://doi.org/10.3389/fncel.2013.00168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036979725
    528 rdf:type schema:CreativeWork
    529 https://doi.org/10.3390/cancers5020462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015395997
    530 rdf:type schema:CreativeWork
    531 https://doi.org/10.3390/cancers7040884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035876933
    532 rdf:type schema:CreativeWork
    533 https://doi.org/10.3390/ijms17050702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043473987
    534 rdf:type schema:CreativeWork
    535 https://doi.org/10.3892/ol.2016.4901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071527663
    536 rdf:type schema:CreativeWork
    537 https://doi.org/10.3892/or.2012.2219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071532225
    538 rdf:type schema:CreativeWork
    539 https://doi.org/10.4161/rna.19985 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072309964
    540 rdf:type schema:CreativeWork
    541 https://doi.org/10.6026/97320630011512 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009808477
    542 rdf:type schema:CreativeWork
    543 https://doi.org/10.7150/ijbs.16968 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084480835
    544 rdf:type schema:CreativeWork
    545 https://www.grid.ac/institutes/grid.448878.f schema:alternateName Sechenov University
    546 schema:name Institute of Molecular Medicine, Sechenov First Moscow State Medical University (Sechenov University), 119146, Moscow, Russia
    547 Research Center for Medical Genetics, 115522, Moscow, Russia
    548 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...