In vitro antifungal activity of metal complexes of a quaternized chitosan derivative with copper ions View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-09-23

AUTHORS

A. V. Il’ina, B. Ts. Shagdarova, A. P. Lun’kov, S. N. Kulikov, V. P. Varlamov

ABSTRACT

Antifungal activity of synthetic metal complexes of quaternized N-(propyl) chitosan derivatives with Сu(II) against yeastlike (Saccharomyces cereviseae, Rodothorula rubra, and Candida albicans) and mycelial fungi (Fusarium oxysporum, Alternaria alternata, Cladosporium herbarum) was studied. In vitro application (at 250‒500 μg/mL) of the metal complex of quaternized N-(propyl) derivative of low-molecular chitosan with 53% substitution and 1.3% copper ions proved efficient against F. оxysporum, one of ten most common fungal plant pathogens. Water-soluble quaternized N-(propyl) chitosan derivatives with 40−58% degree of substitution were synthesized using glycidyltrimethylammonium chloride under optimally adjusted conditions. Metal complexes of the chitosan derivative with 53% degree of substitution with Сu(II) ions were obtained by dialysis. The quantity of copper ions in the metal complexes was determined by atomic emission spectrometry. The structure of chitosan derivatives was confirmed by spectral analysis (IR, 1H NMR). More... »

PAGES

590-595

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s0026261717050101

DOI

http://dx.doi.org/10.1134/s0026261717050101

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091897366


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