Immune complexes that contain HIV antigens activate peripheral blood T cells View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-07

AUTHORS

L. B. Korolevskaya, K. V. Shmagel, E. V. Saidakova, N. G. Shmagel, V. A. Chereshnev

ABSTRACT

Uninfected donor T cells were treated in vitro by model immune complexes that contained either HIV or hepatitis C virus (HCV) antigens. Unlike HCV antigen-containing complexes, the immune complexes that contained HIV antigens have been shown to activate peripheral blood T cells of uninfected donors under in vitro conditions. Both the antiviral antibodies and HIV antigen were involved in the activation process. The unique properties of the immune complexes formed by HIV antigens and antiviral antibodies are believed to result from the virus-specific antibody properties and molecular conformation of the antigen-antibody complex. More... »

PAGES

196-198

References to SciGraph publications

  • 2006-03. HIV disease: fallout from a mucosal catastrophe? in NATURE IMMUNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1134/s0012496616040062

    DOI

    http://dx.doi.org/10.1134/s0012496616040062

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1052544696

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27595830


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